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Methods And Medicament For Inhibition The Expression Of A Defined Gene - EP1798285

The patent EP1798285 was granted to Alnylam Europe on Mar 15, 2017. The application was originally filed on Jan 29, 2000 under application number EP06025389A. The patent is currently recorded with a legal status of "Revoked".

EP1798285

ALNYLAM EUROPE
Application Number
EP06025389A
Filing Date
Jan 29, 2000
Status
Revoked
Jun 28, 2019
Grant Date
Mar 15, 2017
External Links
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SILENCE THERAPEUTICSDec 15, 2017CMS CAMERON MCKENNA NABARRO OLSWANGADMISSIBLE

Patent Citations (12) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication NumberPublication Link
EXAMINATIONWO0136646
OPPOSITIONEP1798285
OPPOSITIONWO0044914
OPPOSITIONWO2004015107
OPPOSITIONWO9932619
SEARCHWO0063364
SEARCHWO9219732
SEARCHWO9805770
SEARCHWO9932619
SEARCHWO9949029
SEARCHWO9953050
SEARCHWO9961631

Non-Patent Literature (NPL) Citations (15) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference TextLink
OPPOSITION- CZAUDERNA F. et al., "Structural variations and stabilising modifications of synthetic siRNAs in mammalian cells", Nucleic Acids Research, (20030000), vol. 31, no. 11, pages 1 - 12, XP055444252-
OPPOSITION- MANCHE, L. et al., "Interactions between Double-Stranded RNA Regulators andthe Protein Kinase DAI", Molecular and Cellular Biology, (19921100), vol. 12, no. 11, pages 5238 - 5248, XP001009924-
OPPOSITION- MONTGOMERY et al., "Double-stranded RNA as a mediator in sequence-specific genetic silencing and co-suppression", TRENDS IN GENETICS, (19980701), vol. 14, no. 7, pages 255 - 258, XP002939521
OPPOSITION- SCHWARZ DS et al., "Evidence that siRNAs Function as Guides, Not Primers, in the Drosophila and Human RNAi Pathways", Molecular Cell, (20020900), vol. 10, no. 3, pages 537 - 548, XP009019083
OPPOSITION- JUDGE et al., "Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA", Nature Biotechnology, (20050320), vol. 23, no. 4, pages 457 - 462, XP002371480
OPPOSITION- SLEDZ, C.A. et al., "Activation of the interferon system by short-interfering RNAs", Nature Cell Biology, (20030901), vol. 5, no. 9, pages 834 - 839, XP009043516
OPPOSITION- HORNUNG et al., "Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7", Nature Medicine, (20050220), vol. 11, no. 3, pages 263 - 270, XP002371477
OPPOSITION- WU et al., "Identification and partial purification of human double strand RNase activity. A novel terminating mechanism for oligoribonucleotide antisense drugs", J. Biol. Chem., (19980130), vol. 273, no. 5, pages 2532 - 2542, XP002234692
OPPOSITION- ELBASHIR SM et al., "Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate", The EMBO Journal, (20011203), vol. 20, no. 23, pages 6877 - 6888, XP002225998
OPPOSITION- ZHENG X. et al., "Activation of the protein kinase PKR by short double-stranded RNAs with single-stranded tails", RNA, (20041200), vol. 10, pages 1934 - 1945, XP055377706
SEARCH- GRYAZNOV S M ET AL, "Template controlled coupling and recombination of oligonucleotide blocks containing thiophosphoryl groups.", NUCLEIC ACIDS RESEARCH. 25 MAR 1993, (19930325), vol. 21, no. 6, ISSN 0305-1048, pages 1403 - 1408, XP002326215 [Y] 22 * the whole document *-
SEARCH- MONTGOMERY M K ET AL, "DOUBLE-STRANDED RNA AS A MEDIATOR IN SEQUENCE-SPECIFIC GENETIC SILENCING AND CO-SUPPRESSION", TRENDS IN GENETICS, ELSEVIER SCIENCE PUBLISHERS B.V. AMSTERDAM, NL, (199807), vol. 14, no. 7, ISSN 0168-9525, pages 255 - 258, XP002939521 [Y] 1-32 * the whole document *
SEARCH- UHLMANN E ET AL, "ANTISENSE OLIGONUCLEOTIDES: A NEW THERAPEUTIC PRINCIPLE", CHEMICAL REVIEWS,US,AMERICAN CHEMICAL SOCIETY. EASTON, (19900601), vol. 90, no. 4, ISSN 0009-2665, pages 543 - 584, XP000141412 [A] 1-32 * Seiten 558,565-566,574-575 *
SEARCH- FIRE ANDREW ET AL, "Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans", NATURE, MACMILLAN JOURNALS LTD. LONDON, GB, (19980219), vol. 391, no. 6669, ISSN 0028-0836, pages 806 - 811, XP002199982 [A] 1-32 * the whole document *
SEARCH- SKRIPKIN E ET AL, "Psoralen crosslinking between human immunodeficiency virus type 1 RNA and primer tRNA3(Lys).", NUCLEIC ACIDS RESEARCH. 1 FEB 1996, (19960201), vol. 24, no. 3, ISSN 0305-1048, pages 509 - 514, XP002326216 [Y] 21 * the whole document *

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