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Oligopeptide-Free Cell Culture Media - EP1974014

The patent EP1974014 was granted to Baxalta on Apr 19, 2017. The application was originally filed on Jan 3, 2007 under application number EP07702574A. The patent is currently recorded with a legal status of "Revoked".

EP1974014

BAXALTA
Application Number
EP07702574A
Filing Date
Jan 3, 2007
Status
Revoked
Jul 3, 2020
Grant Date
Apr 19, 2017
External Links
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Patent Summary

Patent Family

Patent Family

Patent Oppositions (6)

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ALCONADA RODRIGUEZJan 19, 2018ABG LAWADMISSIBLE
MATHYS & SQUIREJan 19, 2018ZWICKERADMISSIBLE
STORZJan 19, 2018-ADMISSIBLE
THOMAEJan 19, 2018WOHLFAHRTADMISSIBLE
CSL BEHRINGJan 18, 2018WISEADMISSIBLE
STRAWMANJan 17, 2018MEWBURN ELLISADMISSIBLE

Patent Citations (29) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication NumberPublication Link
EXAMINATIONWO9808934
INTERNATIONAL-SEARCH-REPORTEP0659880
INTERNATIONAL-SEARCH-REPORTWO2006045438
OPPOSITIONAU2003252890B
OPPOSITIONEP0481791
OPPOSITIONEP0653487
OPPOSITIONEP0659880
OPPOSITIONEP1035212
OPPOSITIONEP1413625
OPPOSITIONEP1482031
OPPOSITIONEP1805298
OPPOSITIONUS2003096366
OPPOSITIONUS2005272124
OPPOSITIONUS4767704
OPPOSITIONUS4786599
OPPOSITIONUS5316938
OPPOSITIONWO0111021
OPPOSITIONWO0123527
OPPOSITIONWO02077202
OPPOSITIONWO03050296
OPPOSITIONWO2004005493
OPPOSITIONWO2006026445
OPPOSITIONWO2006045438
OPPOSITIONWO2006050050
OPPOSITIONWO2007077217
OPPOSITIONWO9808934
OPPOSITIONWO9926470
OPPOSITIONWO9935242
OTHERWO9808934

Non-Patent Literature (NPL) Citations (68) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference TextLink
EXAMINATION- PASTORIAN KIRK E ET AL, "Tolerance to putrescine toxicity in Chinese hamster ovary cells is associated with altered uptake and export", EXPERIMENTAL CELL RESEARCH, (1997), vol. 231, no. 2, ISSN 0014-4827, pages 284 - 295, XP009163335
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EXAMINATION- FRASLON C ET AL, "CULTURE OF FETAL ALVEOLAR EPITHELIAL TYPE II CELLS IN SERUM-FREE MEDIUM", IN VITRO CELLULAR AND DEVELOPMENTAL BIOLOGY, THE ASSOCIATION, GAITHERSBURG, MD, US, (19910101), vol. 27A, no. 11, ISSN 0883-8364, pages 843 - 852, XP009082641
EXAMINATION- ZANG M ET AL, "PRODUCTION OF RECOMBINANT PROTEINS IN CHINESE HAMSTER OVARY CELLS USING A PROTEIN-FREE CELL CULTURE MEDIUM", BIO/TECHNOLOGY, NATURE PUBLISHING CO. NEW YORK, US, (19950401), vol. 13, doi:10.1038/NBT0495-389, ISSN 0733-222X, pages 389 - 392, XP002032677
INTERNATIONAL-SEARCH-REPORT- KATSUTA H ET AL, "EFFECTS OF POLYAMINES ON THE PROLIFERATION OF MAMMALIAN CELLS IN TISSUE CULTURE", JAPANESE JOURNAL OF EXPERIMENTAL MEDICINE, INSTITUTE OF MEDICAL SCIENCE, TOKYO, JP, (197510), vol. 45, no. 5, ISSN 0021-5031, pages 345 - 354, XP009058915 [X] 1-10 * the whole document *-
OPPOSITION- Anonymous, "''31150'' Medium 199", ThermoFisher, (20180117), URL: http://www.thermofisher.com/uk/en/home/technical-resources/media- formulation.294.html, XP055454157-
OPPOSITION- Anonymous, "'32500' DMEM-F12, powder", Thermo Fisher, (20180117), URL: https://www.thermofisher.com/u k/en/home/tech nical-resou rces/media-formulation.218.html, XP055454154-
OPPOSITION- Anonymous, "Dulbecco's Modified Eale's Medium (DME)", DME DATASHEET (SIGMA@), URL: https://www.siqmaaldrich.com/content/dam/siqma-ald rich/docs/Siqma/Formulation/d5546for.pdf-
OPPOSITION- Anonymous, "Minimum Essential Medium Eagle (MEM) Alpha Modifications", SIGMA-ALDRICH, URL: https://www.siqmaaldrich.com/content/dam/siq ma- aldrich/docs/Siqma/Formulation/m0644for.pdf-
OPPOSITION- Anonymous, "Nutrient Mixture F-12 Ham", F-12 DATASHEET (SIGMA®, URL: https://www.siqmaaldrich.com/content/dam/siq ma- aldrich/docs/Siqma/Formulation/1/51651 cfor.pdf-
OPPOSITION- Anonymous, "RPMI-1640 Media Product Information", (SIGMA®), URL: https://www.siqmaaldrich.com/content/dam/siq ma- ald rich/docs/Siq ma/Form u lation/r8758for. pdf-
OPPOSITION- BREITMAIER E. et al., "CHAPTER 12: PEPTIDE UND PROTEINE", ORGANISCHE CHEMIE II, XP055454129-
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OPPOSITION- Froud et al., "Polyamine enhanced product espression from transformed and recombinant cell lines", Froud et al., Spier et al., PRODUCTION OF BIOLOGICALS FROM ANIMAL CELLS IN CULTURE, OXFORD : BUTTERWORTH- HEINEMANN, ESACT, (19910000), pages 107 - 109, XP055454149-
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OPPOSITION- HOLLIDAY, R., "31 Ustilago maydis", HOLLIDAY, R., Robert C King, Handbook of Genetics, (19740000), vol. 1, pages 575 - 595, XP055454609-
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OPPOSITION- KATSUTA et al., "Effects of polyamines on the proliferation of mammalian cells in tissue culture", Japan J Exp Med, (19750000), vol. 45, no. 5, pages 345 - 354, XP009058915-
OPPOSITION- KATSUTA H et al., "EFFECTS OF POLYAMINES ON THE PROLIFERATION OF MAMMALIAN CELLS IN TISSUE CULTURE", JAPANESE JOURNAL OF EXPERIMENTAL MEDICINE , INSTITUTE OF MEDICAL SCIENCE, TOKYO, JP, (19751001), vol. 45, no. 5, pages 345 - 354, XP002359297-
OPPOSITION- LEE et al., "The effects of various hormones and growth factors on the growth of human insulin-producing cell line in serum-free medium", Experimental and Molecular Medicine, (19971200), vol. 29, no. 4, pages 209 - 216, XP055454144-
OPPOSITION- LEE J et al., "THE EFFECTS OF VARIOUS HORMONES AND GROWTH FACTORS ON THE GROWTH OF HUMAN INSULIN-PRODUCING CELL LINE IN SERUM-FREE MEDIUM", EXPERIMENTAL AND MOLECULAR MEDICINE, (19971200), vol. 29, no. 4, pages 209 - 216, XP055454144-
OPPOSITION- LEE, JJ et al., "The effects of various hormones and growth factors on the growth of human insulin-producing cell line in serum-free medium", Exp. Mo. Med., vol. 29, no. 4, pages 209 - 216, XP055454144-
OPPOSITION- LERY, X. et al., "A new serum-free medium for lepidopteran cell culture", J. Inv. Path., (19900000), vol. 55, pages 342 - 349, XP055454533-
OPPOSITION- MORRIS,D.R. et al., "Growth and Macromolecular composition of a mu- tant od Escherichica coli during polyamine limitation", J. Bacteriol., (19730101), vol. 113, no. 1, pages 271 - 277, XP055454165-
OPPOSITION- MURAKAMI H et al., "HORMONAL CONTROL OF HUMAN COLON CARCINOMA CELL GROWTH IN SERUM-FREE MEDIUM", PROC. NATL. ADAC. SCI. USA, (19800600), vol. 77, no. 6, pages 3464 - 3468, XP055454141-
OPPOSITION- Nina Irwin, "Bacterial Media, Antibiotics, and Bacterial Strains", Nina Irwin, Nancy For, Chris Nolan, Michele Ferguson, Molecular Cloning: A Laboratory Manual 2nd ed., Cold Spring Harbor Laboratory Press, (19890000), page A3, XP055454626-
OPPOSITION- Product Information of the protein-free CHO medium -- (WelGENE catalogue no. PF 486-
OPPOSITION- Product leaflet of Ham's F12 medium Post published-
OPPOSITION- R. E. SPIER et al., "Polyamine enhanced product espression from transformed and recombinant cell lines", Production of biologicals from animal cells in culture, Oxford : Butterworth-Heinemann, (19910000), pages 107 - 109, XP055454149-
OPPOSITION- SPIER et al., "Polyamine enhanced product espression from transformed and recombinant cell lines", Production of biologicals from animal cells in culture, Oxford, (19910000), pages 107 - 109, XP055454149-
OPPOSITION- SUGAHARA et al., "Effects of polyamines on proliferation and IgM productivity of human-human hybridoma, HB4C5 cells", Cytotechnology, (20080000), vol. 57, pages 115 - 122, XP019602494-
OPPOSITION- "Technologies for Monoclonal Antibody Production", GIBCO, (20010000), pages 1 - 7, XP055626357-
OPPOSITION- TKACHENKO et al., "Putrescine as a modulator of the level of RNA polymerase [sigma]S subunit in Escherichia coli cells under acid stress", Biochemistry, (20060200), vol. 71, no. 2, pages 185 - 193, XP019294709-
OPPOSITION- ZHOU, W. et al., "Effect of Insulin on a serum-free hybridoma culture", Biotechnol. Bioeng., (19950000), vol. 47, pages 181 - 185, XP055454547
OPPOSITION- PASTORIAN et al., "Tolerance to putrescine toxicity in Chinese hamster ovary cells is associated with altered uptake and export", Exp Cell Res, (19970000), vol. 231, pages 284 - 295, XP009163335
OPPOSITION- PASTORIAN et al., "Tolerance to putrescine toxicity in Chinese hamster ovary cells is associated with altered uptake and export", Experimental Cell Research, (19970000), vol. 231, no. 2, pages 284 - 295, XP009163335
OPPOSITION- PASTORIAN et al., "Tolerance to putrescine toxicity in Chinese hamster ovary cells is associated with altered uptake and export", Expt. Cell res., (19970000), vol. 231, pages 284 - 295, XP009163335
OPPOSITION- PASTOR IAN KIRK E et al., "Tolerance to putrescine toxicity in Chinese hamster ovary cells is associated with altered uptake and export", EXPERIMENTAL CELL RESEARCH, (19970000), vol. 231, no. 2, pages 284 - 295, XP009163335
OPPOSITION- GORFIEN et al., "RECOMBINANT PROTEIN PRODUCTION BY CHO CELLS CULTURED IN A CHEMICALLY DEFINED MEDIUM", Animal Cell Technology: Basic & Applied Aspects, (19970000), vol. 9, pages 247 - 252, XP055626363
OPPOSITION- GANNE et al., "APPLICATINO OF STATISTICAL DESIGN OF EXPERIMENTS TO THE OPTIMIZATION OF FACTOR VIII EXPRESSION BY CHO CELLS", CYTOTECHNOLOGY, (19910000), vol. 6, pages 233 - 240, XP055314449
OPPOSITION- GANNE et al., "Application of statistical design of experiments to the optimization of factor VIII expression by CHO cells", Cytotechnology, (19910000), vol. 6, pages 233 - 240, XP055314449
OPPOSITION- WILSON H C et al., "THE EFFECTS OF VARIOUS NUTRITIONAL SUPPLEMENTS ON THE GROWTH, MIGRATION AND DIFFERENTIATION OF XENOPUS LAEVIS NEURAL CREST CELLS IN VITRO", IN VITRO CELLULAR AND DEVELOPMENTAL BIOLOGY, MD , US, (19870500), vol. 23, no. 5, pages 323 - 331, XP009082638
OPPOSITION- FRASLON C et al., "CULTURE OF FETAL ALVEOLAR EPITHELIAL TYPE II CELLS IN SERUM-FREE MEDIUM", IN VITRO CELLULAR AND DEVELOPMENTAL BIOLOGY, MD , US, (19910000), vol. 27 A, no. 11, pages 843 - 852, XP009082641
OPPOSITION- KIM D et al., "EFFECTS OF SUPPLEMENTATION OF VARIOUS MEDIUM COMPONENTS ON CHINESE HAMSTER OVARY CELL CULTURES PRODUCING RECOMBINANT ANTIBODY", CYTOTECHNOLOGY, (20050000), vol. 47, pages 37 - 49, XP019236882
OPPOSITION- KIM et al., "Effects of Supplementation of Various Medium Components on Chinese Hamster Ovary Cell Cultures Producing Recombinant Antibody", Cytotechnology, (20050000), vol. 47, no. 1-3, pages 37 - 49, XP019236882
OPPOSITION- KIM et al., "DEVELOPMENT OF A SERUM-FREE MEDIUM FOR THE PRODUCTION OF HUMANIZED ANTIBODY FROM CHINESE HAMSTER OVARY CELLS USING A STATISTICAL DESIGN", IN VITRO CELL DEV BIOL ANIMAL, (19980000), vol. 34, pages 757 - 761, XP055314431
OPPOSITION- KIM et al., "Development of a Serum-Free Medium for the Production of Humanized Antibody from Chinese Hamster Ovary Cells Using a Statistical Design", In Vitro Cell . Dev. Biol. - Animal, (19981200), vol. 34, pages 757 - 761, XP055314431
OPPOSITION- KIM et al., "Development of a Serum-Free Medium for the Production of Humanized Antibody from Chinese Hamster Ovary Cells Using a Statistical Design", IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY. ANIMAL, (19980000), vol. 34, pages 757 - 761, XP055314431
OPPOSITION- HAM R, "Putrescine and related amines as growth factors for a mammalian cell line", Biochem Biophys Res Commun., (19640000), vol. 14, no. 1, pages 34 - 38, XP024838961
OPPOSITION- MIYAZAKI et al., "Spermine enhances IgM productivity of human-human hybridoma HB4C5 cells and human peripheral blood lymphocytes", Cytotechnology, (19980000), vol. 26, pages 111 - 118, XP019236524
OPPOSITION- MIYAZAKI et al., "SPERMINE ENHANCES IGM PRODUCTIVITY OF HUMAN-HUMAN HYBRIDOMA HB4C5 CELLS AND HUMAN PERIPHERAL BLOOD LYMPHOCYTES", CYTOTECHNOLOGY, (19980300), vol. 26, no. 2, pages 111 - 8, XP019236524
OPPOSITION- ZANG et al., "Production of recombinant proteins in Chinese hamster ovary cells using a protein free cell culture medium", Biotechnology, (19950000), vol. 13, pages 389 - 392, XP001344740
OPPOSITION- ZANG et al., "Production of Recombinant Proteins in Chinese Hamster Ovary Cells Using A Protein-Free Cell Culture Medium", Biotechnology, (19950400), vol. 13, pages 389 - 392, XP001344740
OPPOSITION- ZANG M et al., "PRODUCTION OF RECOMBINANT PROTEINS IN CHINESE HAMSTER OVARY CELLS USING A PROTEIN-FREE CELL CULTURE MEDIUM", BIO/TECHNOLOGY, NEW YORK, US, (19950413), pages 389 - 392, XP002032677
OPPOSITION- LEE, K.C. et al., "S100A7 (Psoriasin) - Mechanism of Antibacterial Actions in Wounds", J Invest Derm., (20070000), vol. 127, pages 945 - 957, XP055649002
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OPPOSITION- FUSI et al., "Effects of putrescine, cadaverine, spermine, spermidine and β-phenylethylamine on cultured bovine mammary epithelial cells", Ital. J. Anim. Sci, (20080000), vol. 7, pages 131 - 140, XP055314462
OTHER- "CHAPTER 12: PEPTIDE UND PROTEINE", BREITMAIER E. ET AL, ORGANISCHE CHEMIE II, GEORG THIEME VERLAG, (1983), page 391, XP003035089-
OTHER- FALBE J. ET AL, RÖMPP CHEMIE LEXIKON, ED.9, GEORG THIEME VERLAG, (1995), pages 3268 - 3269, XP003035090-

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