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Sub-Diffraction Limit Image Resolution And Other Imaging Techniques - EP2049933

The patent EP2049933 was granted to The President And Fellows OF Harvard College on Mar 2, 2022. The application was originally filed on Aug 7, 2007 under application number EP07872605A. The patent is currently recorded with a legal status of "Patent Maintained As Amended".

EP2049933

THE PRESIDENT AND FELLOWS OF HARVARD COLLEGE
Application Number
EP07872605A
Filing Date
Aug 7, 2007
Status
Patent Maintained As Amended
Jan 28, 2022
Publication Date
Mar 2, 2022
External Links
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CARL ZEISSAug 22, 2018LORITZ -

Patent Citations (6) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication Number
EXAMINATIONWO2006127692
INTERNATIONAL-SEARCH-REPORTUS2002064789
INTERNATIONAL-SEARCH-REPORTUS2006038993
OPPOSITIONUS2002064789
OPPOSITIONWO2006127692
OPPOSITIONWO2007128434

Non-Patent Literature (NPL) Citations (18) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference Text
EXAMINATION- BETZIG E ET AL, "Imaging Intracellular Fluorescent Proteins at Nanometer Resolution", SCIENCE, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE, WASHINGTON, DC; US, vol. 313, no. 5793, doi:10.1126/SCIENCE.1127344, ISSN 0036-8075, (20060915), pages 1642 - 1645, (20060810), XP002523342
INTERNATIONAL-SEARCH-REPORT- M. BATES ET AL., "Short-Range Spectroscopic Ruler Based on a Single-Molucule Optical Switch", PHYSICAL REVIEW LETTERS, (20050318), vol. 94, no. 108101, pages 108101-1 - 108101-4, XP002492583 [X] 1-187,200-211 * the whole document *
INTERNATIONAL-SEARCH-REPORT- METTHEW ANTONIK ET AL., "Separating Structural Heterogeneities from Stochastic Variations in Fluorescence Resonance Energy Transfer Distributions via Photon Distribution Analysis", J. PHYS. CHEM. B, (20060315), vol. 110, no. 13, pages 6970 - 6978, XP002492586 [A] * the whole document *
INTERNATIONAL-SEARCH-REPORT- MICHAEL J. RUST ET AL., "Sub-diffraction-limit imaging by stochastic optical reconstruction microscopy (STORM)", NATURE METHODS, (20060809), vol. 3, no. 10, pages 793 - 795, XP002492582 [PXD] 1 * the whole document *
INTERNATIONAL-SEARCH-REPORT- SATOSHI HABUCHI ET AL., "Reversible single-molecule photoswitching in the GFP-like fluorescent protein Dronpa", PNAS, (20050705), vol. 102, no. 27, pages 9511 - 9516, XP002492584 [A] * the whole document *
INTERNATIONAL-SEARCH-REPORT- HOFMANN M ET AL, "Breaking the diffraction barrier in fluorescence microscopy at low light intensities by using reversibly photoswitchable proteins", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE, WASHINGTON, DC, (20051206), vol. 102, no. 49, ISSN 0027-8424, pages 17565 - 17569, XP002448241 [X] 1,78,79,124,125,153,177-179,187,200 * the whole document *
INTERNATIONAL-SEARCH-REPORT- LARRY J. FRIEDMAN ET AL., "Viewing Dynamic Assembly of Molucular Complexes by Muti-Wavelength Single-Molecule Fluorescence", BIOPHYSICAL JOURNAL, (20060512), vol. 91, pages 1023 - 1031, XP002492585 [A] * the whole document *
OPPOSITION- Anonymous, "NIH VideoCast - Frontiers in Live Cell Imaging (Day 3)", (20060421), URL: https://videocast.nih.gov/summary.asp?Live=4926&bhcp=1, XP055517283
OPPOSITION- BATES et al., "Short-range spectroscopic ruler based on a single-molecule optical switch", PHYSICAL REVIEW LETTERS, (20050318), vol. 94, no. 10, pages 108101-1 - 108101-4, XP002492583
OPPOSITION- Galperin Emilia, Et Al, "Three-chromophore FRET microscopy to analyze multiprotein interactions in living cells", Nature Methods, (20041201), vol. 1, no. 3, pages 209 - 217, XP055790951
OPPOSITION- Hohng Sungchul, Et Al, "Single-Molecule Three-Color FRET", Biophysical Journal, Biophysical Society, (20040801), vol. 87, pages 1328 - 1337, XP055790943
OPPOSITION- Chudakov, D.M. Lukyanov, S. Lukyanov, K.A., "Fluorescent proteins as a toolkit for in vivo imaging", TRENDS IN BIOTECHNOLOGY, GB, (20051201), vol. 23, no. 12, doi:10.1016/j.tibtech.2005.10.005, ISSN 0167-7799, pages 605 - 613, XP005182978
OPPOSITION- HEILEMANN et al., "Carbocyanine Dyes as Efficient Reversible Single-Molecule Optical Switch", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY,, (20050222), vol. 127, no. 11, pages 3801 - 3806, XP002505791
OPPOSITION- Lukyanov Konstantin A; Chudakov Dmitry M; Lukyanov Sergey; Verkhusha Vladislav V, "Photoactivatable fluorescent proteins", Nat Rev Mol Cell Biology, London, (20051101), vol. 6, no. 11, doi:10.1038/nrm1741, ISSN 1471-0072, pages 885 - 891, XP009107283
OPPOSITION- T. LACOSTE, X. MICHALET, F. PINAUD, D. CHEMLA, P. ALIVISATOS, S. WEISS, "ultrahigh-resolution multicolor colocalization of single fluorescent probes", Proceedings of the National Academy of Sciences, US, (20000815), vol. 97, no. 17, doi:10.1073/pnas.170286097, ISSN 0027-8424, pages 9461 - 9466, XP002458687
OPPOSITION- PATTERSON et al., "A Photoactivatable GFP for Selective Photolabeling of Proteins and Cells", Science, (20020913), vol. 297, pages 1873 - 1877, XP055087031
OPPOSITION- BETZIG E., ET AL, "Imaging Intracellular Fluorescent Proteins at Nanometer Resolution", Science, American Association for the Advancement of Science, US, (20060915), vol. 313, no. 5793, doi:10.1126/SCIENCE.1127344, ISSN 0036-8075, pages 1642 - 1645, XP002523342
OPPOSITION- HESS S T, GIRIRAJAN T P K, MASON M D, "Ultra-High Resolution Imaging by Fluorescence Photoactivation Localization Microscopy", BIOPHYSICAL JOURNAL, AMSTERDAM, NL, (20061201), vol. 91, no. 11, doi:10.1529/BIOPHYSJ.106.091116, ISSN 0006-3495, pages 4258 - 4272, XP002523343

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