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Circulating Mutant Dna To Assess Tumor Dynamics - EP2315849

The patent EP2315849 was granted to The Johns Hopkins University on Nov 8, 2017. The application was originally filed on Jul 31, 2009 under application number EP09803662A. The patent is currently recorded with a legal status of "Revoked".

EP2315849

THE JOHNS HOPKINS UNIVERSITY
Application Number
EP09803662A
Filing Date
Jul 31, 2009
Status
Revoked
May 29, 2020
Grant Date
Nov 8, 2017
External Links
Slate, Register, Google Patents

Patent Summary

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Patent Family

Patent Oppositions (2)

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ROCHEAug 8, 2018ADMISSIBLE
JAMES POOLEAug 7, 2018ADMISSIBLE

Patent Citations (5) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication NumberPublication Link
DESCRIPTIONUS20040562840-
INTERNATIONAL-SEARCH-REPORTUS2003143600
OPPOSITIONUS2003143600
OPPOSITIONUS2008161420
OPPOSITIONWO2007050465

Non-Patent Literature (NPL) Citations (50) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference TextLink
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DESCRIPTION- CRISTOFANILLI, M. ET AL., "Circulating tumor cells, disease progression and survival in metastatic breast cancer", N. ENGL. J. MED., (2004), vol. 351, doi:doi:10.1056/NEJMoa040766, pages 781 - 791, XP002458149
DESCRIPTION- DIEHL, F. ET AL., "Detection and quantification of mutations in the plasma of patients with colorectal tumors", PROC. NATL. ACAD. SCI. USA, (2005), vol. 102, doi:doi:10.1073/pnas.0507904102, pages 16368 - 16373, XP002518285
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INTERNATIONAL-SEARCH-REPORT- DIEHL ET AL., "Analysis of Mutations in DNA Isolated From Plasma and Stool of Colorectal Cancer Patients.", GASTROENTEROLOGY., (20080515), vol. 135, no. 2, pages 489 - 498, XP023901355
OPPOSITION- Frank Diehl et al, "Supplementary Information Circulating Mutant DNA to Assess Tumor Dynamics", Nature Medicine, (20070731), pages 1 - 22, XP055394399-
OPPOSITION- Frank Diehl et al., "Supplementary Information Circulating Mutant DNA to Assess Tumor Dynamics", Nature Medicine, (20070731), pages 1 - 22, XP055394399-
OPPOSITION- "Supplemantary Appendix to Detection of Mutations in EGFR in Circulating Lung-Cancer Cells", New England Journal of Medicine, (20080000), page 6pp, XP055509751-
OPPOSITION- YAMADA et al., "Detection of K-ras gene mutations in plasma DNA of patients with pancreatic adenocarcinoma: correlation with clinicopathological features", Clin Cancer Res, (19980000), vol. 4, pages 1527 - 1532, XP055509785-
OPPOSITION- SCHMID et al., "Tumor burden index as a prognostic tool for cutaneous T-cell lymphoma", Archives In Dermatology, (19990000), vol. 135, pages 1204 - 1208, XP002666724
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OPPOSITION- DIEHL, F. et al., "Circulating mutant DNA to assess tumor dynamics", Nat Med., (20080731), vol. 14, no. 9, pages 985 - 990, XP002666722
OPPOSITION- MENG et al., "BEAMing up for detection and quantification of rare sequence variants", Nature Methods, (20060000), vol. 3, pages 95 - 97, XP008126872
OPPOSITION- DIEHL et al., "Analysis of Mutations in DNA Isolated From Plasma and Stool of Colorectal Cancer Patients", Gastroenterology, (20080000), vol. 135, pages 489 - 498, XP023610068
OPPOSITION- DIEHL, F. et al., "Analysis of Mutations in DNA Isolated From Plasma and Stool of Colorectal Cancer Patients", Gastroenterology, (20080800), vol. 135, no. 2, pages 489 - 498, 498e1-498e7, XP023610068
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OPPOSITION- DIEHL et al., "Detection and quantification of mutations in the plasma of patients with colorectal tumors", PNAS USA, (20051108), vol. 102, no. 45, pages 16368 - 16373, XP007809665
OPPOSITION- DIEHL, F. et al., "Detection and quantification of mutations in the plasma of patients with colorectal tumors", PNAS, (20051108), vol. 102, no. 45, pages 16368 - 16373, XP007809665
OPPOSITION- RYAN, B. M. et al., "A prospective study of circulating mutant KRAS2 in the serum of patients with colorectal neoplasia: string prognostic indicator in postoperative follow up", Gut, (20030000), vol. 52, pages 101 - 108, XP002666723
OPPOSITION- RYAN et al., "A prospective study of circulating mutant KRAS2 in the serum of patients with colorectal neoplasia: string prognostic indicator in postoperative follow up", Gut, (20030000), vol. 52, pages 101 - 108, XP002666723
OPPOSITION- RAGO, C. et al., "Serial Assessment of Human Tumor Burdens in Mice by the Analysis of Circulating DNA", Cancer Res, (20070000), vol. 67, no. 19, pages 9364 - 9370, XP055288572
OPPOSITION- RAGO et al., "Serial Assessment of Human Tumor Burdens in Mice by the Analysis of Circulating DNA", Cancer Research, (20070000), vol. 67, pages 9364 - 9370, XP055288572
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SEARCH- DIEHL F ET AL., "Circulating mutant DNA to assess tumor dynamics", NATURE MEDICINE, (20080731), vol. 14, no. 9, pages 985 - 990, XP002666722 [XP] 1-13 * the whole document * * published online 31 July 2008 *
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SEARCH- DIEHL FRANK ET AL, "Detection and quantification of mutations in the plasma of patients with colorectal tumors", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE, WASHINGTON, DC; US, vol. 102, no. 45, doi:10.1073/PNAS.0507904102, ISSN 0027-8424, (20051108), pages 16368 - 16373, URL: 10.1073/pnas.0507904102, XP002518285 [Y] 1-13 * the whole document *
SEARCH- RYAN B M ET AL., "A prospective study of circulating mutant KRAS2 in the serum of patients with colorectal neoplasia: string prognostic indicator in postoperative follow up", GUT, (200301), vol. 52, no. 1, pages 101 - 108, XP002666723 [Y] 1-4,7-13 * the whole document *

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