The patent EP2459555 was granted to Krka on Nov 3, 2021. The application was originally filed on Jul 30, 2010 under application number EP10740170A. The patent is currently recorded with a legal status of "Granted And Under Opposition".

Patent oppositions filed by competitors challenge the validity of a granted patent. These oppositions are typically based on claims of prior art, lack of novelty, or non-obviousness. They are a key part of the process for determining a patent's strength and enforceability.
Patent citations refer to prior patents cited during different phases such as opposition or international search.
| Citation Phase | Publication Number | 
|---|---|
| DESCRIPTION | DE10129725 | 
| DESCRIPTION | WO0147919 | 
| DESCRIPTION | WO2004060887 | 
| DESCRIPTION | WO2005068456 | 
| DESCRIPTION | WO2007039132 | 
| INTERNATIONAL-SEARCH-REPORT | WO0147919 | 
| INTERNATIONAL-SEARCH-REPORT | WO2004060887 | 
| INTERNATIONAL-SEARCH-REPORT | WO2007039132 | 
| INTERNATIONAL-SEARCH-REPORT | WO2009074249 | 
| OPPOSITION | US2005182055 | 
| OPPOSITION | US7351823 | 
| OPPOSITION | WO0147919 | 
| OPPOSITION | WO2007039132 | 
| OPPOSITION | WO2010075631 | 
| OPPOSITION | WO2014020458 | 
| OTHER | US2005182055 | 
| OTHER | US7157456 | 
| OTHER | US7351823 | 
| OTHER | US8188270 | 
| OTHER | WO0147919 | 
| OTHER | WO2007039132 | 
| OTHER | WO2010075631 | 
NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.
| Citation Phase | Reference Text | 
|---|---|
| DESCRIPTION | - JOURNAL OF MEDICINAL CHEMISTRY, (2005), vol. 48, pages 5900 - 5908 | 
| INTERNATIONAL-SEARCH-REPORT | - ROEHRIG S ET AL, "Discovery of the Novel Antithrombotic Agent 5-Chloro-N-(((5S)-2-oxo-3 [4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl)methyl)thiophene 2-carboxamide (BAY 59-7939): An Oral, Direct Factor Xa Inhibitor", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY, WASHINGTON, US LNKD- DOI:10.1021/JM050101D, (20050922), vol. 48, ISSN 0022-2623, pages 5900 - 5908, XP002418821 [XD] 1 * page 5903, paragraph 2 * | 
| OPPOSITION | - Falbe Jürgen, Manfred Regitz, "Waschen", RÖMPP CHEMIELEXIKON, T-Z, Thieme Verlag, (19920101), page 4990, XP093108201 | 
| OPPOSITION | - Furniss Brian, Et Al, Furniss Brian, Et Al, Vogel A. I.; Furniss B.S.; Hannaford A.J.; Smith P.W.G.; Tatchell A.R., Vogel's Textbook of Practical Organic Chemistry, Harlow , Addison Wesley Longman Limited , (19890101), pages 135 - 153, ISBN 978-0-582-46236-6, XP055950142 | 
| OTHER | - BRIAN S. FURNISS et al., Vogel's Textbook of Practical Organic Chemistry, (19890000), pages 135 - 153, XP055580749 | 
| OTHER | - Brian S Furniss; Et Al, Vogel's Textbook of Practical Organic Chemistry. 5th ed,, Longman Scientific & Technical, (19890000), pages 135 - 142, XP055580749 | 
| OTHER | - GIULIETTI M; SECKLER M M; DERENZO S; RÉ M I; CEKINSKI E, "INDUSTRIAL CRYSTALLIZATION AND PRECIPITATION FROM SOLUTIONS: STATE OF THE TECHNIQUE", BRAZILIAN JOURNAL OF CHEMICAL ENGINEERING,, (20011200), vol. 18, no. 4, pages 423 - 440, XP002563840 | 
| OTHER | - M.GIULIETTI, "INDUSTRIAL CRYSTALLIZATION AND PRECIPITATION FROM SOLUTIONS: STATE OF THE TECHNIQUE", Braz. J. Chem. Eng., (20011200), vol. 18, no. 4, XP002563840 | 
| OTHER | - "RECRYSTALLISATION TECHNIOUES", Brian S. Furniss et al, Vogel's Textbook of Practical Organic Chemistry. 5th ed., Longman Scientific & Technical, (19890000), pages 135 - 153, XP055580749 | 
| OTHER | - Morissette S, "High-throughput crystallization: polymorphs, salts, co-crystals and solvates of pharmaceutical solids", Advanced Drug Delivery Reviews, (20040000), vol. 56, pages 275 - 300, XP055531004 | 
| OTHER | - SHERRY L. MORISSETTEA, "High-throughput crystallization: polymorphs, salts, co-crystals and solvates of pharmaceutical solids", Advanced Drug Delivery Reviews, (20040000), vol. 56, pages 275 - 300, XP009072233 | 
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Oct 30, 2025
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Decision to grant a European patent
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Sep 22, 2021
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Sep 22, 2021
Filing of the translations of the claims
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Sep 22, 2021
French translation of claims
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Sep 22, 2021
German translation of the claims
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Sep 22, 2021
Letter accompanying subsequently filed items
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Intention to grant (signatures)
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May 19, 2021
Text intended for grant (clean copy)
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Amended description with annotations
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Description
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Patent document filed by a Third party
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Observations by third parties
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Annex to the communication
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Oct 15, 2020
Communication from the Examining Division
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Mar 20, 2020
Decision to allow further processing
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Mar 13, 2020
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Mar 13, 2020
Amended claims with annotations
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Mar 13, 2020
Claims
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Letter accompanying subsequently filed items
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Request for further processing
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Letter accompanying subsequently filed items
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Annex to the communication
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Communication from the Examining Division
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Letter accompanying subsequently filed items
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Amended claims with annotations
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Claims
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Letter accompanying subsequently filed items
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Letter accompanying subsequently filed items
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Annex to the communication
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Oct 5, 2015
Communication from the Examining Division
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Sep 23, 2015
Examination started
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Jul 13, 2015
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Submission concerning representation
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May 19, 2014
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Jul 22, 2013
Payment of fees and costs
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Jun 13, 2013
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Amendments received before examination
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Dec 24, 2012
Observations by third parties
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(Electronic) Receipt
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Nov 7, 2012
Letter accompanying subsequently filed items
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Nov 7, 2012
Request for a decision
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Oct 25, 2012
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Feb 22, 2012
(Electronic) Receipt
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Feb 22, 2012
Request for entry into the European phase
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Feb 14, 2012
Dec 7, 2011
Information on entry into European phase
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Feb 25, 2011
Feb 3, 2011
Copy of the international search report
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Feb 3, 2011
Published international application - A1
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Dec 23, 2010
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Jul 30, 2010
Abstract
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Jul 30, 2010
Claims
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Jul 30, 2010
Description
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