IP Verse

Delivery Of Mrna For The Augmentation Of Proteins And Enzymes In Human Genetic Diseases - EP2506857

The patent EP2506857 was granted to Shire Human Genetic Therapies on Feb 14, 2018. The application was originally filed on Nov 30, 2010 under application number EP10835016A. The patent is currently recorded with a legal status of "Revoked".

EP2506857

SHIRE HUMAN GENETIC THERAPIES
Application Number
EP10835016A
Filing Date
Nov 30, 2010
Status
Revoked
May 4, 2024
Grant Date
Feb 14, 2018
External Links
Slate, Register, Google Patents

Patent Summary

Patent Family

Patent Family

Patent Oppositions (2)

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BRADYNov 14, 2018EIPADMISSIBLE
WITHERS & ROGERSNov 14, 2018GRAF VON STOSCH PATENTANWALTSGESELLSCHAFTADMISSIBLE

Patent Citations (31) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication NumberPublication Link
INTERNATIONAL-SEARCH-REPORTUS2005054026
INTERNATIONAL-SEARCH-REPORTUS2006083780
INTERNATIONAL-SEARCH-REPORTUS2006172003
INTERNATIONAL-SEARCH-REPORTUS2006204566
INTERNATIONAL-SEARCH-REPORTUS2007252295
INTERNATIONAL-SEARCH-REPORTUS2008260706
INTERNATIONAL-SEARCH-REPORTUS6147055
INTERNATIONAL-SEARCH-REPORTUS6670178
INTERNATIONAL-SEARCH-REPORTUS6743823
OPPOSITIONEP1026253
OPPOSITIONUS5580859
OPPOSITIONUS5912159
OPPOSITIONUS6077835
OPPOSITIONUS6734171
OPPOSITIONWO2005120152
OPPOSITIONWO2007024708
OPPOSITIONWO2008052770
OPPOSITIONWO2009086558
OPPOSITIONWO9011092
OPPOSITIONWO9851278
OPPOSITIONWO9918933
OTHEREP1026253
OTHERUS5580859
OTHERUS5912159
OTHERUS6077835
OTHERUS6734171
OTHERWO2005120152
OTHERWO2007024708
OTHERWO2008052770
OTHERWO9851278
SEARCHWO9011092

Non-Patent Literature (NPL) Citations (21) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference TextLink
OPPOSITION- PATHAK et al., "Nano-vectors for efficient liver specific gene transfer", Int J Nanomed, (20080000), vol. 3, no. 1, pages 31 - 49, XP055422063-
OPPOSITION- SCHERPHOF et al., "Uptake of Liposomes by Rat and Mouse Hepatocytes and Kupffer Cells", Biol Cell, (19830000), vol. 47, pages 47 - 58, XP055530819-
OPPOSITION- Stanley T. Crooke, "Antisense Drug Technology: Principles, Strategies, and Applications, Second Edition", Liposomal Formulations for Nucleic Acid Delivery, (20070725), pages 237 - 270, XP055534618-
OPPOSITION- WILSON et al., "Ex Vivo Gene Therapy of Familial Hypercholesterolemia", Hum Gene Ther., (19920400), vol. 3, no. 2, pages 179 - 222, XP055422061-
OPPOSITION- DASSA et al., "Expression of the alternative oxidase complements cytochrome coxidase deficiency in human cells", EMBO Mol Med., (20090400), vol. 1, no. 1, page 306, XP055422071
OPPOSITION- MONCK et al., "Versatility in lipid compositions showing prolonged circulation with sterically stabilized liposomes", J Drug Target., (19920400), vol. 1105, no. 2, pages 193 - 200, XP055530843
OPPOSITION- WOODLE et al., "Versatility in lipid compositions showing prolonged circulation with sterically stabilized liposomes", Biochim Biophys Acta, (19920000), vol. 1105, no. 2, pages 193 - 200, XP023574846
OPPOSITION- Li S D et al, "Nanoparticles evading the reticuloendothelial system: Role of the supported bilayer", Biochim Biophys Acta, (20091000), vol. 1788, no. 10, pages 2259 - 2266, XP026684876
OPPOSITION- YAMAMOTO et al., "Current prospects for mRNA gene delivery", Eur. J. of Pharmaceutical and Biopharm, (20081010), vol. 71, pages 484 - 489, XP025992169
OPPOSITION- HEYES et al., "Cationic lipid saturation influences intracellular delivery of encapsulated nucleic acids", Journal of Controlled Release, (20050728), vol. 107, no. 2, pages 276 - 287, XP005076220
OPPOSITION- WISSE et al., "The size of endothelial fenestrae in human liver sinusoids: implications for hepatocyte-directed gene transfer", Gene Therapy (2008, (20080410), vol. 15, no. 17, pages 1193 - 1199, XP055534609
OPPOSITION- FELGNER et al., "LIPOFECTON: A HIGHLY EFFICIENT, LIPID-MEDIATED DNA-TRANSFECTION PROCEDURE", Proc Natl Acad Sci USA, (19870000), vol. 84, no. 21, pages 7413 - 7417, XP000602252
OPPOSITION- MALONE et al., "CATIONIC LIPOSOME-MEDIATED RNA TRANSFECTION", Proc Natl Acad Sci USA, (19890000), vol. 86, no. 16, pages 6077 - 6081, XP000604642
OPPOSITION- SAMEERSINGH et al., "The effect of circulation lifetime and drug-to-lipid ratio of intravenously administered lipid nanoparticles on the biodistribution and immunostimulatory activity of encapsulated CpG-ODN", Journal of Drug Targeting, (20080900), vol. 16, no. 7-8, pages 564 - 577, XP055534629
OPPOSITION- KUBO et al., "Mismatch Repair Protein Deficiency Is a Risk Factor for AberrantExpression of HLA Class I Molecules: A Putative 11AdaptiveImmune Escape11 Phenomenon", Anticancer Res., (20170300), vol. 37, no. 3, pages 1289 - 1295, XP055422058
OTHER- PATHAK et al., "Nano-vectors for efficient liver specific gene transfer", Int J Nanomed, (20080300), vol. 3, no. 1, pages 31 - 49, XP055422063-
OTHER- WILSON et al., "Ex Vivo Gene Therapy of Familial Hypercholesterolemia", Hum Gene Ther, (19920400), vol. 3, no. 2, pages 179 - 222, XP055422061-
OTHER- DASSA et al., "Expression of the alternative oxidase complements cytochrome coxidase deficiency in human cells", EMBO Mol Med., (20090400), vol. 1, no. 1, page 306, XP055422071
OTHER- "Li et al.", Biochim Biophys Acta, (20091000), vol. 1788, no. 10, pages 2259 - 2266, XP026684876
OTHER- KUBO et al., "Mismatch Repair Protein Deficiency Is a Risk Factor for AberrantExpression of HLA Class I Molecules: A Putative 11AdaptiveImmune Escape11 Phenomenon", Anticancer Res., (20170317), vol. 37, no. 3, pages 1289 - 1295, XP055422058
SEARCH- JIAN WU ET AL, "Modification of liposomes for liver targeting", JOURNAL OF HEPATOLOGY, (19960601), vol. 24, no. 6, doi:10.1016/S0168-8278(96)80274-1, ISSN 0168-8278, pages 757 - 763, XP055101270 [A] 1-17 * page 757, column l, paragraph l - column r, paragraph 1 * * page 758, column r, paragraph 2 - page 759, column l, paragraph 1 * * page 760, column l, paragraph l - page 761, column l, paragraph 1 * * page 761, column r, paragraph 3 * * page 761, column r, paragraph l - page 762 *

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Dossier Documents

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