Wash Solution And Method For Affinity Chromatography - EP2513134

The patent EP2513134 was granted to Novartis on Sep 6, 2017. The application was originally filed on Dec 17, 2010 under application number EP10790452A. The patent is currently recorded with a legal status of "Revoked".

EP2513134

NOVARTIS
Application Number
EP10790452A
Filing Date
Dec 17, 2010
Status
Revoked
Sep 3, 2024
Grant Date
Sep 6, 2017
External Links
Slate, Register, Google Patents

Patent Summary

Patent Family

Patent Family

Patent Oppositions (4)

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MORPHOSYSJun 6, 2018SPILLERADMISSIBLE
WEINZIERLJun 6, 2018SCHIWECK WEINZIERL KOCH PATENTANWALTE PARTNERSCHAFT MBBADMISSIBLE
HOFFMANN EITLEJun 5, 2018HOFFMANN EITLEADMISSIBLE
OETKEJun 4, 2018WALLINGERADMISSIBLE

Patent Citations (24) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication NumberPublication Link
DESCRIPTIONUS2003050450
DESCRIPTIONUS2005176109
DESCRIPTIONUS2008064860
DESCRIPTIONUS2008064861
DESCRIPTIONUS6127526
DESCRIPTIONUS6333398
DESCRIPTIONUS6870034
DESCRIPTIONUS7501495
DESCRIPTIONWO2008031020
INTERNATIONAL-SEARCH-REPORTEP0333474
INTERNATIONAL-SEARCH-REPORTUS2007060741
INTERNATIONAL-SEARCH-REPORTUS2008051340
INTERNATIONAL-SEARCH-REPORTWO2008031020
OPPOSITIONEP0333474
OPPOSITIONUS2005107594
OPPOSITIONUS2007060741
OPPOSITIONUS2008051340
OPPOSITIONUS4704366
OPPOSITIONUS6870034
OPPOSITIONWO2007081851
OPPOSITIONWO2007109163
OPPOSITIONWO2007143161
OPPOSITIONWO2008031020
OPPOSITIONWO2011073389

Non-Patent Literature (NPL) Citations (23) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference TextLink
EXAMINATION- "Affi-Prep - Protein A Matrix Instruction Manual LIT-230 Rev B", (20000101), URL: http://www.bio-rad.com/webroot/web/pdf/lsr/literature/LIT230.pdf, (20131128), XP055090731-
EXAMINATION- "GE Healthcare Data File 18-1149-94 AE Affinity chromatography: MabSelect", Uppsala, (20080401), URL: http://www.gelifesciences.co.jp/catalog/pdf/18114994.pdf, (20131128), XP055090722-
EXAMINATION- "Protein A Antibody Purification Handbook", Littleton, MA, USA, (20050101), URL: http://www.protein-chem.com/Resources/proteus A.3.pdf, (20131128), XP055090724-
OPPOSITION- "AE Affinity chromatography: MabSelect", GE Healthcare Data File - 18-1149-94, (20080401), XP055496051-
OPPOSITION- Affi-Prep - Protein A Matrix Instruction Manual, (20000101), URL: http://www.bio- rad.com/webroot/web/pdf/Isr/literature/LIT230.pdf, XP055090731-
OPPOSITION- "Affi-Prep - Protein A Matrix Instruction Manual LIT-230 Rev B", Bio-Rad, (20000101), URL: http://www.bio-rad.com/webroot/web/pdf/Isr/literature/LIT230.pdf, XP055090731-
OPPOSITION- BARRON et al., "Improving Purity on Protein A Affinity Chromatography Media throughuse of an Arginine Intermediate Wash Step", IPCOM000127319D, (20050822), XP055495111-
OPPOSITION- EJIMA, D. et al., "Arginine as an effective additive in gel permeation chromatography", Journal of Chromatography A, (20050000), vol. 1094, no. 1-2, pages 49 - 55, XP027722902-
OPPOSITION- ELIN MONIE, "Evaluation of the 96-well format for screening of chromatographicbuffer conditions", Master's degree Project, (20061000), ISSN 1401-2138, XP055495100-
OPPOSITION- "GE Healthcare Data File 18-1149-94 AE Affinity chromatography: MabSelect", GE Healthcare, Uppsala, (20080401), URL: http://www.gelifesciences.co.jp/catalog/pdf/18114994.pdf, XP055090722-
OPPOSITION- GE, "High-throughput screening and optimization of a Protein A capture step in a monoclonal antibody purification", GE Healthcare Application Note 28-9468-58 AB High-throughput process development, (20090900), pages 1 - 8, XP055496058-
OPPOSITION- GRÖNBERG et al., "A Strategy for Developing a Monoclonal Antibody Purification Platform", BioProcess Int., (20070000), vol. 5, no. 1, pages 48 - 55, XP055495108-
OPPOSITION- "High-throughput screening and optimization of a Protein A capture step in a monoclonal antibody purification process", Application note 28-9468-58 AB High-throughput process development, (20090900), pages 1 - 8, XP055496058-
OPPOSITION- "Improving Purity on Protein A Affinity Chromatography Media through use of an Arginine Intermediate Wash Step", Millipore Technical Brief, (20050000), XP055495111-
OPPOSITION- "Increasing Purity on ProSep@-vA Affinity Chromatography Media using an Intermediate Wash Step", Millipore Technical Brief, (20060000), XP055496517-
OPPOSITION- "Protein A Antibody Purification Handbook", (20050101), XP055090724-
OPPOSITION- "Screening od effective column rinse solvent for Protein-A chromatography", PROTEIN EXPRESSION AND PURIFICATION, (20100000), vol. 70, pages 218 - 223-
OPPOSITION- The Protein Protocols Handbook, New Jersey, (20020000), pages 993 - 994 , 999-1001 and 1121-1128, XP055496077-
OPPOSITION- GHOSE et al., "Binding capacity differences for antibodies and Fc-fusion proteins on protein A chromatographic materials", Biotechnology and Bioengineering, (20070000), vol. 96, no. 4, pages 768 - 779, XP055087495
OPPOSITION- GHOSE, S. et al., "Binding Capacity Differences for Antibodies and Fc-Fusion Protein on A Chromatographic Materials", Biotechnology and Bioengineering, vol. 96, no. 4, (20070000), pages 768 - 779, (20070301), XP055087495
OPPOSITION- YUMIOKA et al., "Screening of effective column rinse solvent for Protein-A chromatography", Protein Expression and Purification, (20100000), vol. 70, no. 2, pages 218 - 223, XP026915656
OPPOSITION- YUMIOKA, R. et al., "Screening of effective column rinse solvent for Protein-A chromatography", Protein Expression and Purification, vol. 70, no. 2, (20100000), pages 218 - 223, (20091006), XP026915656
OPPOSITION- TSUMOTO et al., "Review - Why is Arginine Effective in Suppressing Aggregation?", Protein & Peptide Letters, (20051000), vol. 12, no. 7, pages 613 - 619, XP009090675

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