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Differentiation Of Human Embryonic Stem Cells - EP2569419

The patent EP2569419 was granted to Janssen Biotech on Mar 20, 2019. The application was originally filed on May 11, 2011 under application number EP11781200A. The patent is currently recorded with a legal status of "Revoked".

EP2569419

JANSSEN BIOTECH
Application Number
EP11781200A
Filing Date
May 11, 2011
Status
Revoked
Jun 21, 2025
Grant Date
Mar 20, 2019
External Links
Slate, Register, Google Patents

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Patent Citations (8) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication Number
OPPOSITIONUS2009263896
OPPOSITIONWO2005116073
OPPOSITIONWO2006105152
OPPOSITIONWO2009132083
OPPOSITIONWO2011079017
OPPOSITIONWO2011143299
SEARCHUS2009263896
SEARCHWO2009132083

Non-Patent Literature (NPL) Citations (14) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference Text
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EXAMINATION- MING-KO CHIANG ET AL, "Single-Cell Transcript Analysis of Pancreas Development", DEVELOPMENTAL CELL, US, (20030301), vol. 4, no. 3, doi:10.1016/S1534-5807(03)00035-2, ISSN 1534-5807, pages 383 - 393, XP055408825
EXAMINATION- JUN CAI ET AL, "Generation of homogeneous PDX1+ pancreatic progenitors from human ES cell-derived endoderm Cells", THE JOURNAL OF CELL BIOLOGY : JCB, THE ROCKEFELLER UNIVERSITY PRESS, US, (20091112), vol. 2, ISSN 0021-9525, pages 50 - 60, XP008159565
EXAMINATION- ROSEN ET AL, "BMP and BMP inhibitors in bone", ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, NEW YORK ACADEMY OF SCIENCES, US, (20060101), vol. 1068, doi:10.1196/ANNALS.1346.005, ISSN 0077-8923, pages 19 - 25, XP009096200
OPPOSITION- MFOPOU et al., "- Noggin, Retinoids, and Fibroblast Growth Factor Regulate Hepatic or Pancreatic Fate of Human Embryonic Stem Cells", Gastroenterology, (20100600), vol. 138, no. 7, XP027094483
OPPOSITION- CHEN et al., "A small molecule that directs differentiation of human ESCs into the pancreatic lineage", Nature Chemical Biology, (20090000), vol. 5, no. 4, pages 258 - 265, XP008164145
OPPOSITION- IYPE et al., "The Transcriptional Repressor Nkx6.1 Also Functions as a Deoxyribonucleic Acid ContextDependent Transcriptional Activator during Pancreatic p-Cell Differentiation: Evidence for Feedback Activation of the nkx6.. 1 Gene by Nkx6.1", Molecular Endocrinology, (20040600), vol. 18, no. 6, pages 1363 - 1375, XP055666770
SEARCH- ALI A S ET AL, "Exploitation of protein kinase C: A useful target for cancer therapy", CANCER TREATMENT REVIEWS, SAUNDERS, US, vol. 35, no. 1, doi:10.1016/J.CTRV.2008.07.006, ISSN 0305-7372, (20090201), pages 1 - 8, (20080907), XP025891992 [A] 3-15 * abstract *
SEARCH- DONGHUI ZHANG ET AL, "Highly efficient differentiation of human ES cells and iPS cells into mature pancreatic insulin-producing cells", CELL RESEARCH, (20090401), vol. 19, no. 4, doi:10.1038/cr.2009.28, ISSN 1001-0602, pages 429 - 438, XP055074920 [A] 1-15 * abstract * * figure 1 *
SEARCH- D'AMOUR K A ET AL, "Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells", NATURE BIOTECHNOLOGY, NATURE PUBLISHING GROUP, NEW YORK, NY, US, (20060101), vol. 24, no. 11, doi:10.1038/NBT1259, ISSN 1087-0156, pages 1392 - 1401, XP002423119 [A] 1-15 * abstract * * figure 1 *
SEARCH- KROON EVERT ET AL, "Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo", NATURE BIOTECHNOLOGY, NATURE PUBLISHING GROUP, NEW YORK, NY, US, vol. 26, no. 4, doi:10.1038/NBT1393, ISSN 1087-0156, (20080401), pages 443 - 452, (20080220), XP002561975 [A] 1-15 * abstract * * figure 1 *
SEARCH- SHUIBING CHEN ET AL, "A small molecule that directs differentiation of human ESCs into the pancreatic lineage", NATURE CHEMICAL BIOLOGY, NATURE PUB. GROUP, vol. 5, no. 4, doi:10.1038/NCHEMBIO.154, ISSN 1552-4450, (20090401), pages 258 - 265, (20090315), XP008164145 [X] 1-6 * abstract * * "ILV functions by activating PKC signaling"; page 263 * [I] 7-15
SEARCH- JUN CAI ET AL, "Generation of homogeneous PDX1+ pancreatic progenitors from human ES cell-derived endoderm Cells", THE JOURNAL OF CELL BIOLOGY : JCB, THE ROCKEFELLER UNIVERSITY PRESS, US, (20091112), vol. 2, ISSN 0021-9525, pages 50 - 60, XP008159565 [A] 1-15 * abstract * * figure 7 *
SEARCH- HYO-JONG LEE ET AL, "PKC-[delta] inhibitors sustain self-renewal of mouse embryonic stem cells under hypoxia in vitro", EXPERIMENTAL AND MOLECULAR MEDICINE, (20100101), vol. 42, no. 4, doi:10.3858/emm.2010.42.4.028, ISSN 1226-3613, page 294, XP055102651 [A] 3-15 * abstract *

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