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Antitumor T Cell Response Enhancer - EP2578231

The patent EP2578231 was granted to Chugai Seiyaku Kabushiki Kaisha on Oct 26, 2022. The application was originally filed on May 27, 2011 under application number EP11786748A. The patent is currently recorded with a legal status of "Revoked".

EP2578231

CHUGAI SEIYAKU KABUSHIKI KAISHA
Application Number
EP11786748A
Filing Date
May 27, 2011
Status
Revoked
Feb 14, 2025
Grant Date
Oct 26, 2022
External Links
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GEDEON RICHTER PHARMAJul 25, 2023MAIWALDADMISSIBLE

Patent Citations (52) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication NumberPublication Link
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Non-Patent Literature (NPL) Citations (57) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference TextLink
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OPPOSITION- Satoru Shinriki, Hirofumi Jono, Kazutoshi Ota, Mitsuharu Ueda, Mareina Kudo, Tomoko Ota, Yuichi Oike, Motoyoshi Endo, Mutsuko Ibusuki, Akimitsu Hiraki, Hideki Nakayama, Yoshihiro Yoshitake, Masanori Shinohara and Yukio Ando, "Humanized Anti-Interleukin-6 Receptor Antibody Suppresses Tumor Angiogenesis and In vivo Growth of Human Oral Squamous Cell Carcinoma", Clinical Cancer Research, US, (20090901), vol. 15, no. 17, doi:10.1158/1078-0432.CCR-09-0287, ISSN 1078-0432, pages 5426 - 5434, XP002628465
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OPPOSITION- Kuna Mareina, Jono Hirofumi, Shinriki Satoru, Yano Shigetoshi, Nakamura Hideo, Makino Keishi, Hide Takuichiro, Muta Daisuke, Ueda Mitsuharu, 0ta Kazutoshi, Ando Yukio, Kuratsu Jun-Ichi, "Anti tumor effect of humanized anti-interleukin-6 receptor antibody {tocilizumab) on glioma cell proliferation Laboratory investigation", J Neurosurg ., (20090801), vol. 111, no. 2, doi:10.3171/2008.12.JNS081284, pages 219 - 225, XP093090642
OPPOSITION- OSTRAND-ROSENBERG SUZANNE, SINHA PRATIMA, "Myeloid-Derived Suppressor Cells: Linking Inflammation and Cancer", The Journal of Immunology, Williams & Wilkins Co., US, US , (20090415), vol. 182, no. 8, doi:10.4049/JIMMUNOL.0802740, ISSN 0022-1767, pages 4499 - 4506, XP002588069
OPPOSITION- Almand Bond, Clark Joseph I., Nikitina Ekaterina, Van Beynen James, English Nicholas R., Knight Stella C., Carbone David P., Gabrilovich Dmitry I., "Increased Production of Immature Myeloid Cells in Cancer Patients: A Mechanism of Immunosuppression in Cancer", The Journal of Immunology, Williams & Wilkins Co., US, US , (20010101), vol. 166, no. 1, doi:10.4049/jimmunol.166.1.678, ISSN 0022-1767, pages 678 - 689, XP093147220
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SEARCH- J. VINCENT ET AL, "5-Fluorouracil Selectively Kills Tumor-Associated Myeloid-Derived Suppressor Cells Resulting in Enhanced T Cell-Dependent Antitumor Immunity", CANCER RESEARCH, (20100415), vol. 70, no. 8, doi:10.1158/0008-5472.CAN-09-3690, ISSN 0008-5472, pages 3052 - 3061, XP055080069 [X] 1,7 * abstract * * page 3052, column r, paragraph 1 * [Y] 2-6,8-12
SEARCH- E. SUZUKI, "Gemcitabine Selectively Eliminates Splenic Gr-1+/CD11b+ Myeloid Suppressor Cells in Tumor-Bearing Animals and Enhances Antitumor Immune Activity", CLINICAL CANCER RESEARCH, (20050915), vol. 11, no. 18, doi:10.1158/1078-0432.CCR-05-0883, ISSN 1078-0432, pages 6713 - 6721, XP055080337 [X] 1,7 * abstract * * page 6713, column r - page 6714, column l, paragraph 1 * * page 6715, column l, paragraph 4 * * page 6715, column r, paragraph 2 - paragraph 4 * * page 6718 - page 6719, column l, paragraph 1 * * page 6719, column l, paragraph 2 - paragraph 3 * * page 6719, column r, paragraph 2 - page 6720, column l, paragraph 1 * * page 6720, column r, paragraph 2 * * page 6721, column r, paragraph 2 * [Y] 2-6,8-12
SEARCH- DULUC DOROTH�E ET AL, "Tumor-associated leukemia inhibitory factor and IL-6 skew monocyte differentiation into tumor-associated macrophage-like cells.", MEDLINE, US NATIONAL LIBRARY OF MEDICINE (NLM), BETHESDA, MD, US, (20071215), Database accession no. NLM17848619, XP002713350 [X] 1,3-5,7 * abstract * [Y] 2-5,8-12
SEARCH- ZANGARI MAURIZIO ET AL, "Immunomodulatory drugs in multiple myeloma.", EXPERT OPINION ON INVESTIGATIONAL DRUGS NOV 2005, (200511), vol. 14, no. 11, ISSN 1744-7658, pages 1411 - 1418, XP002713351 [X] 1,7 * abstract * [I] 3-5 [Y] 2-5,8-12
SEARCH- SEBBA ANTHONY, "Tocilizumab: the first interleukin-6-receptor inhibitor.", MEDLINE, US NATIONAL LIBRARY OF MEDICINE (NLM), BETHESDA, MD, US, (20080801), Database accession no. NLM18653811, XP002713356 [A] 1-12 * abstract *

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