Means And Methods For The Prediction Of Treatment Response Of A Cancer Patient - EP2619576

The patent EP2619576 was granted to Grabe on Jun 10, 2020. The application was originally filed on Sep 20, 2011 under application number EP11773381A. The patent is currently recorded with a legal status of "Granted And Under Opposition".

EP2619576

GRABE
Application Number
EP11773381A
Filing Date
Sep 20, 2011
Status
Granted And Under Opposition
May 8, 2020
Grant Date
Jun 10, 2020
External Links
Slate, Register, Google Patents

Patent Summary

Patent Family

Patent Family

Patent Oppositions

Patent oppositions filed by competitors challenge the validity of a granted patent. These oppositions are typically based on claims of prior art, lack of novelty, or non-obviousness. They are a key part of the process for determining a patent's strength and enforceability.

CompanyOpposition DateRepresentativeOpposition Status

Get instant alerts for new oppositions and patent status changes

PLOUGMANN VINGTOFTMar 9, 2021PLOUGMANN VINGTOFTADMISSIBLE

Patent Citations (4) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication NumberPublication Link
DESCRIPTIONUS7871769
INTERNATIONAL-SEARCH-REPORTUS2005260646
INTERNATIONAL-SEARCH-REPORTWO2007045996
OPPOSITIONWO2007045996

Non-Patent Literature (NPL) Citations (49) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference TextLink
DESCRIPTION- AJCC Cancer Staging Manual, LIPPINCOTT, (1997), pages 171 - 180-
DESCRIPTION- BENVENUTI ET AL., CANCER RES, (2007), vol. 67, pages 2643 - 2648-
DESCRIPTION- DENKERT ET AL., J. CLIN. ONCOL., (2009), pages 105 - 113-
DESCRIPTION- DIEDERICHSEN ET AL., CANCER IMMUNOL, IMMUNOTHER., (2003), vol. 52, pages 423 - 428-
DESCRIPTION- FARMER ET AL., NAT MED, (2009), vol. 15, pages 68 - 74-
DESCRIPTION- FARMER ET AL., NATURE MEDICINE, (2009), vol. 15, pages 68 - 74-
DESCRIPTION- GALON ET AL., SCIENCE, (2006), vol. 313, pages 1960 - 1964-
DESCRIPTION- GRUJIL ET AL., BRITISH JOURNAL OF CANCER, (1999), vol. 79, pages 1127 - 1132-
DESCRIPTION- HALAMA ET AL., ANAL QUANT CYTOL HISTOL., (2010), vol. 32, pages 333 - 340-
DESCRIPTION- HALAMA ET AL., ANAL QUANT CYTOL HISTOL, (2010), vol. 32, pages 333 - 40-
DESCRIPTION- ISHIGAMI ET AL., CANCER, (2002), vol. 94, no. 5, pages 1437 - 1442-
DESCRIPTION- KUSS ET AL., BRITISH JOURNAL OF CANCER, (2003), vol. 88, pages 223 - 230-
DESCRIPTION- MAKI ET AL., J. GASTROENTEROLGY AND HEPATOLOGY, (2004), vol. 19, pages 1348 - 1356-
DESCRIPTION- MENON ET AL., LAB INVEST., (2002), vol. 82, pages 1725 - 33-
DESCRIPTION- MENON ET AL., LAB INVEST., (2004), vol. 84, pages 493 - 501-
DESCRIPTION- MORONI ET AL., LANCET ONCOL, (2005), vol. 6, pages 279 - 86-
DESCRIPTION- MORONI, M ET AL., LANCET ONCOL, (2005), vol. 6, pages 279 - 286-
DESCRIPTION- MORRIS ET AL., CLIN CANCER RES., (2008), vol. 14, pages 1413 - 1417-
DESCRIPTION- NISTICO ET AL., INT. J. CANCER, (1999), vol. 84, pages 598 - 603-
DESCRIPTION- OSHOKIRI ET AL., JOURNAL OF SURGICAL ONCOLOGY, (2003), vol. 84, pages 224 - 228-
DESCRIPTION- PAGES ET AL., NEW ENGLAND JOURNAL OF MEDICINE, (2005), vol. 353, pages 2654 - 2666-
DESCRIPTION- PHILIPS ET AL., BRITISH JOURNAL OF SURGERY, (2004), vol. 91, pages 469 - 475-
DESCRIPTION- PRADO-GARCIA ET AL., LUNG CANCER, (2005), vol. 47, pages 361 - 371-
DESCRIPTION- REICHERT ET AL., CLINICAL CANCER RESEARCH, (2002), vol. 8, pages 3137 - 3145-
DESCRIPTION- VALMORI ET AL., CANCER RESEARCH, (2002), vol. 62, pages 1743 - 1750-
DESCRIPTION- ZHANG ET AL., NEW ENGLAND JOURNAL OF MEDICINE, (2003), vol. 348, no. 3, pages 203 - 213-
EXAMINATION- GRANETTO CRISTINA ET AL, "Correlation between the prognostic value of tumor-infiltrating lymphocytes (TILS) and sidedness in colorectal cancer (CC) patients (pts)", ANNALS OF ONCOLOGY, (20170628), page iii94, XP055465224-
EXAMINATION- BERGHOFF ANNA SOPHIE ET AL, "Tumor infiltrating lymphocytes and PD-L1 expression in brain metastases of small cell lung cancer (SCLC)", JOURNAL OF NEURO-ONCOLOGY, KLUWER, BOSTON, US, vol. 130, no. 1, doi:10.1007/S11060-016-2216-8, ISSN 0167-594X, (20160719), pages 19 - 29, (20160719), XP036080079
EXAMINATION- N. Halama ET AL, "Localization and Density of Immune Cells in the Invasive Margin of Human Colorectal Cancer Liver Metastases Are Prognostic for Response to Chemotherapy", Cancer research, (20110816), vol. 71, no. 17, doi:10.1158/0008-5472.CAN-11-0268, ISSN 0008-5472, pages 5670 - 5677, XP055015732
EXAMINATION- DIRK JÄGER ET AL, "Immunotherapy of Colorectal Cancer", ONCOLOGY RESEARCH AND TREATMENT, CH, (20160601), vol. 39, no. 6, doi:10.1159/000446713, ISSN 2296-5270, pages 346 - 350, XP055389446
EXAMINATION- NIELS HALAMA ET AL, "Hepatic metastases of colorectal cancer are rather homogeneous but differ from primary lesions in terms of immune cell infiltration", ONCOIMMUNOLOGY, (20130401), vol. 2, no. 4, doi:10.4161/onci.24116, page e24116, XP055465117
INTERNATIONAL-SEARCH-REPORT- N. HALAMA ET AL, "The localization and density of immune cells in primary tumors of human metastatic colorectal cancer shows an association with response to chemotherapy.", CANCER IMMUNITY, Academy of Cancer Immunology. Exchange Plaza 55 Broadway, Suite 1802 New York, NY 10006 USA, (20080218), vol. 9, no. 1, pages 1 - 6, XP055015805 [I] 1-5,7-22 * page 1, abstract, last two lines; page 2, Table 1. * [A] 6,23-31-
INTERNATIONAL-SEARCH-REPORT- M. MORRIS ET AL, "Tumor-Infiltrating Lymphocytes and Perforation in Colon Cancer Predict Positive Response to 5-Fluorouracil Chemotherapy", CLINICAL CANCER RESEARCH, American Association for Cancer Research | 615 Chestnut St. 17th Floor, Philadelphia, PA 19106 USA, (20080301), vol. 14, no. 5, doi:10.1158/1078-0432.CCR-07-1994, ISSN 1078-0432, pages 1413 - 1417, XP055015814 [A] 1-31 * page 1416, column 2, paragraph 1 *
OPPOSITION- "Carboplatin", Wikipedia, (20210113), URL: https://en.wikipedia.org/wiki/Carboplatin, XP055790163-
OPPOSITION- HALAMA et al., "Immunological tumor maps: a landscape of infiltrating immune cells in colorectal cancer based on complete tissue section analyses", Proceedings of the American Association for Cancer Research, (20100400), vol. 51, page 465, XP055790146-
OPPOSITION- HALAMA et al., "Quantification of prognostic immune cell markers in colorectal cancer using whole slide imaging tumor maps", Anal Quant Cytol Histol, (20101200), vol. 32, no. 6, pages 333 - 340, XP009167037-
OPPOSITION- HALAMA et al., "The localization and density of immune cells in primary tumors of human metastatic colorectal cancer shows an association with response to chemotherapy", Cancer Immunity, (20090200), vol. 9, pages 1 - 6, XP055440022-
OPPOSITION- "Paclitaxel", Wikipedia, (20210212), URL: https://en.wikipedia.org/wiki/Paclitaxel, XP055790166-
OPPOSITION- "Sorafenib", Wikipedia, (20210106), URL: https://en.wikipedia.org/wiki/Sorafenib, XP055790168-
OPPOSITION- YAGI et al., "The importance of optical optimization in whole slide imaging (WSI) and digital pathology imaging", Diagnostic Pathology, (20080000), vol. 3, pages 1 - 3, XP021039283-
OPPOSITION- GANNON et al., "Characterization of the intra-prostatic immune cell infiltration in androgen-deprived prostate cancer patients", J Immunol Methods, (20090831), vol. 348, no. 1-2, pages 9 - 17, XP026470608
OPPOSITION- GALON et al., "Type, density, and location of immune cells within human colorectal tumors predict clinical outcome", Science, (20060929), vol. 313, no. 5795, pages 1960 - 1964, XP002684010
OPPOSITION- HALAMA et al., "Localization and Density of Immune Cells in the Invasive Margin of Human Colorectal Cancer Liver Metastases Are Prognostic for Response to Chemotherapy", Cancer Res., (20110816), vol. 71, no. 17, pages 5670 - 5677, XP055015732
OPPOSITION- GARCIA ROJO et al., "Critical comparison of 31 commercially available digital slide systems in pathology", Int J Surg Pathol., (20060000), vol. 14, no. 4, pages 285 - 305, XP002664839
OPPOSITION- DENKERT et al., "Tumor-Associated Lymphocytes As an Independent Predictor of Response to Neoadjuvant Chemotherapy in Breast Cancer", J Clin Oncol, (20100101), vol. 28, no. 1, pages 105 - 113, XP055160521
OPPOSITION- HALAMA et al., "Estimation of Immune Cell Densities in Immune Cell Conglomerates: An Approach for High-Throughput Quantification", PLoS One, (20090000), vol. 4, no. 11, XP002691992
OPPOSITION- GARCIA ROJO et al., "Review of imaging solutions for integrated quantitative immunohistochemistry in the Pathology daily practice", Folia Histochem Cytobiol, (20090100), vol. 47, no. 3, pages 349 - 354, XP055247918
OPPOSITION- HALAMA et al., "The local immunological microenvironment in colorectal cancer as a prognostic factor for treatment decisions in the clinic: The way ahead", Oncoimmunology, (20120000), vol. 1, no. 1, pages 62 - 66, XP009167023
OPPOSITION- HALAMA et al., "Hepatic metastases of colorectal cancer are rather homogeneous but differ from primary lesions in terms of immune cell infiltration", Oncoimmunology, (20130000), vol. 2, no. 4, pages 1 - 10, XP055465117

Download Citation Report

Get a free citation report including examiner, opposition, and international search citations.

Get Citation Report

Dossier Documents

The dossier documents provide a comprehensive record of the patent’s prosecution history - including filings, correspondence, and decisions made by patent offices - and are crucial for understanding the patent’s legal journey and any challenges it may have faced during examination.

  • Date

    Description

  • Get instant alerts for new documents