IP Verse

Method For The Production Of Immunoglobulin Single Variable Domains - EP2632946

The patent EP2632946 was granted to Ablynx on Dec 6, 2017. The application was originally filed on Oct 28, 2011 under application number EP11775994A. The patent is currently recorded with a legal status of "Opposition Rejected".

EP2632946

ABLYNX
Application Number
EP11775994A
Filing Date
Oct 28, 2011
Status
Opposition Rejected
Jul 5, 2024
Grant Date
Dec 6, 2017
External Links
Slate, Register, Google Patents

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Patent Citations (55) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication NumberPublication Link
DESCRIPTIONWO2011EP60738-
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DESCRIPTIONWO03025020
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DESCRIPTIONWO2004062551
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DESCRIPTIONWO2006040153
DESCRIPTIONWO2006079372
DESCRIPTIONWO2006122786
DESCRIPTIONWO2006122787
DESCRIPTIONWO2006122825
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DESCRIPTIONWO9425591
DESCRIPTIONWO9504079
DESCRIPTIONWO9634103
DESCRIPTIONWO9749805
DESCRIPTIONWO9923221
DESCRIPTIONWO9937681
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INTERNATIONAL-SEARCH-REPORTWO2008142164
INTERNATIONAL-SEARCH-REPORTWO2010125187
OPPOSITIONUS2008274101
OPPOSITIONUS7459425
OPPOSITIONWO2006030220
OPPOSITIONWO2008142164
OPPOSITIONWO2010056550
OPPOSITIONWO2010125187

Non-Patent Literature (NPL) Citations (22) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference TextLink
OPPOSITION- AHN et al., "BiopharmaLynx: A new bioinformatics tool for automated LC/MS peptide mapping assignment", Waters - the science of what is possible, (20080900), pages 1 - 6, XP055731028-
OPPOSITION- ANONYMOUS, "EasySelect (TM) Pichia Expression Kit", Invitrogen - Life technologies, (20100000), pages I-VIII,1 - 87, URL: http://tools.invitrogen.com/content/sfs/manuals/easyselect_man.pdf, XP055015858-
OPPOSITION- ANONYMOUS, "Pichia Fermentation Process Guidelines", Invitrogen - Life technologies, (20020000), pages 1 - 11, URL: http://tools.invitrogen.com/content/sfs/manuals/pichiaferm_prot.pdf, XP055015860-
OPPOSITION- Boerner, Kathleen Clouse, "Defining Your Product Profile and Maintaining Control Over It Part 3", BioProcess Technical, (20051000), pages 51 - 56, XP055731022-
OPPOSITION- "Carbamylation", Vincent Lee, Peptide and Protein Drug Discovery, CRC press, (19900000), page 189, XP055519505-
OPPOSITION- "Chapter 5", GÜNTER JAGSCHIES et al., Handbook of Process Chromatography: Development, Manufacturing, Validation and Economics, Elsevier, (20080000), pages 127 - 135, XP055519484-
OPPOSITION- "chapter 6", CREGG et al., Methods in Molecular Biology. Pichia protocols, 2nd ed., Humana Press, (20070000), pages 77-79,94 - 95, XP055519500-
OPPOSITION- J. Richard Dickinson, Michael Schweizer, J. Richard Dickinson, Michael Schweizer, J. Richard Dickinson, Michael Schweizer, THE METABOLISM AND MOLECULAR PHYSIOLOGY OF SACCHAROMYCES CEREVISIAE, CRC PRESS, (20040000), pages 1 - 476-
OPPOSITION- König Helmut, Unden Gottfried, Fröhlich Jürgen, Biology of Microorganisms on Grapes in Must and in Wine, Springer, (20090000), pages 1 - 521-
OPPOSITION- Marc Carnicer, Kristin Baumann, Isabelle Töplitz, Francesc Sánchez-Ferrando, Diethard Mattanovich, Pau Ferrer & Joan Albiol, "Macromolecular and Elemental Composition Analysis and Extracellular Metabolite Balances of Pichia pastoris growing at different oxygen levels", Microbial Cell Factories, (20091200), page 14, XP021067674-
OPPOSITION- O. Boué, O. Farnós, A. González, R. Fernández, J.A. Acosta, R. Valdés, L.J. González, Y. Guanche, G. Izquierdo, M. Suárez, I. Domínguez, H. Machado, M. Rodríguez & R. Lleonart, "Production and biochemical characterization of the recombinant Boophilus microplus Bm95 antigen from Pichia pastoris", Experimental and Applied Acarology, (20040000), vol. 32, pages 119 - 128, XP055731099-
OPPOSITION- Paul Rainville, Kefei Zheng, Claude Mallet, Reb Russell II, Detecting Carbamylation of Intact Proteins and Peptides by LC/MS(/MS, (20020000), page 1, XP055731108-
OPPOSITION- STARK et al., "The use of cyanate for the determination of NH2-terminal residues in proteins", J. Biol. Chem., (19630000), vol. 238, no. 1, pages 214 - 226, XP055519482-
OPPOSITION- STARK G. R. et al., "Reactions of the cyanate present in aqueous urea with amino acids and proteins", J. Biol. Chem., (19601100), vol. 235, no. 11, pages 3177 - 3181, XP055519480-
OPPOSITION- "The Gold Sheet", Pharmaceutical & Biotechnology Quality Control, (20040900), vol. 38, no. 9, pages 1 - 32, XP055731017-
OPPOSITION- Zolodz M D; Herberg J T; Narepekha H E; Raleigh E; Farber M R; Dufield R L; Boyle D M, "Separation by hydrophobic interaction chromatography and structural determination by mass spectrometry of mannosylated glycoforms of a recombinant transferrin-extendin-4 fusion protein from yeast", Journal of Chromatography A, (20091000), pages 225 - 234, XP026817105-
OPPOSITION- HARMSEN et al., "Properties, production, and applications of camelid single-domain antibody fragments", Appl Microbiol Biotechnol, (20071100), vol. 77, no. 1, pages 13 - 22, XP055519503
OPPOSITION- MIDDELHOVEN, "The pathway of arginine breakdown in Saccharomyces cerevisiae", Biochim. Biophys. Acta, (19640000), vol. 93, doi:10.1016/0304-4165(64)90349-6, pages 650 - 652, XP025792842
OPPOSITION- LIN et al., "Ion chromatographic quantification of cyanate in urea solutions: estimation of the efficiency of cyanate scavengers for use in recombinant protein manufacturing", Journal of Chromatography, (20040425), vol. 803, no. 2, pages 353 - 362, XP004500042
OPPOSITION- RAHBARIZADEH et al., "Over expression of anti-MUC1 single-domain antibody fragments in the yeast Pichia pastoris", MOLECULAR IMMUNOLOGY, (20060201), vol. 43, no. 5, pages 426 - 435, XP025037145
OPPOSITION- RAHBARIZADEH et al., "High expression and purification of the recombinant camelid anti-MUC1 single domain antibodies in Escherichia coli", PROTEIN EXPRESSION AND PURIFICATION, (20051101), pages 32 - 38, XP027390195
OPPOSITION- K Kitamoto, K Oda, K Gomi, K Takahashi, "Genetic Engineering of a Sake Yeast Producing No Urea by Successive Disruption of Arginase Gene", Applied and Environmental Microbiology, (19910000), vol. 57, pages 301 - 306, XP055731032

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