IP Verse

Improved Process For The Culturing Of Cells - EP2634250

The patent EP2634250 was granted to DPX on Apr 5, 2017. The application was originally filed on Jul 4, 2007 under application number EP13169694A. The patent is currently recorded with a legal status of "Revoked".

EP2634250

DPX
Application Number
EP13169694A
Filing Date
Jul 4, 2007
Status
Revoked
Nov 6, 2020
Grant Date
Apr 5, 2017
External Links
Slate, Register, Google Patents

Patent Summary

Patent Family

Patent Family

Patent Oppositions (3)

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REPLIGENJan 5, 2018CONROYWITHDRAWN
BOEHRINGER INGELHEIM PHARMA BOEHRINGER INGELHEIMJan 4, 2018HOFERADMISSIBLE
BAXALTADec 21, 2017HOFFMANN EITLEADMISSIBLE

Patent Citations (26) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication NumberPublication Link
DESCRIPTIONEP0833934
DESCRIPTIONUS5994128
DESCRIPTIONUS6544424
DESCRIPTIONUS6855544
DESCRIPTIONUS6994128
DESCRIPTIONWO0138362
DESCRIPTIONWO2004099396
DESCRIPTIONWO2005095578
OPPOSITIONDE10120835
OPPOSITIONEP2041259
OPPOSITIONEP2308958
OPPOSITIONEP2343362
OPPOSITIONEP2634242
OPPOSITIONEP2634243
OPPOSITIONUS4806484
OPPOSITIONUS5286646
OPPOSITIONUS6544424
OPPOSITIONUS6855544
OPPOSITIONWO2004099396
OPPOSITIONWO2005095578
OPPOSITIONWO2008006494
OPPOSITIONWO2008152075
SEARCHUS4806484
SEARCHUS5286646
SEARCHWO2004099396
SEARCHWO2005095578

Non-Patent Literature (NPL) Citations (46) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference TextLink
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OPPOSITION- "Batch culture", Medical dictionary, (20160000), URL: http://medical-dictionary.thefreedictionary.com/batch+culture, XP055447415-
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OPPOSITION- "Cross-flow filtration", Wikipedia, the free encyclopedia, (20130909), page 5, URL: https://en.wikipedia.org/wiki/Cross-flow_filtration, XP055450513-
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OPPOSITION- "Fed-batch culture", Wikipedia, the free encyclopedia, (20160222), pages 1 - 5, URL: https://en.wikipedia.org/wiki/Fed-batch culture, XP055447440-
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OPPOSITION- FUREY, "Scale-up of a Cell Culture Perfusion Process", Genetic engineering News, (20020401), vol. 22, no. 7, pages 62 - 63, XP055296597-
OPPOSITION- GRIFFITHS B., "Scale-Up of Suspension and Anchorage-Dependent Animal Cells", Molecular Biotechnology, (20010300), vol. 17, no. 3, pages 225 - 238, XP055450509-
OPPOSITION- HOPKINSON, J, "Hollow Fiber Cell Culture Systems For Economical Cell -Product Manufacturing", BIO/TECHNOLOGY, (19850300), vol. 3, no. 3, pages 225 - 230, XP055450409-
OPPOSITION- J. BONHAM-CARTER et al., "Developments in cell culture perfusion processes and their scale-up to manufacturing", ESACT UK annual meeting, (20050107), pages 1 - 28, XP055341192-
OPPOSITION- KOROS W.J. et al., "Terminology for membranes and membrane proc- esses", Pure & Applied Chem., (19960000), vol. 68, no. 7, pages 1479 - 1489, XP000918963-
OPPOSITION- MATSUMURA et al., "Effects of ainmonium ion removal on growth and MAb production of hybridoma cells", Cytotechnology, (19950100), vol. 18, no. 1-2, pages 35 - 50, XP055341206-
OPPOSITION- Millipore, "Protein concentration and diafiltration by Tangential flow Filtration", Technical Brief, (20030000), pages 1 - 24, XP002376847-
OPPOSITION- Millipore, "Protein Concentration and Diafiltration by Tangen- tial Flow Filtration", Technical Brief, Billerica, (20030603), pages 1 - 24, XP002376847-
OPPOSITION- Millipore, "Scale-up quickly and realiably with Pellicon Tangetial flow filtration cassettes", Broschüre, (19990300), pages 1 - 8, XP055450550-
OPPOSITION- Pieter de Geus, "The human PER.C6® manufacturing platform", 1st Annual PER.C6® Technology Conference, (20070510), XP055341233-
OPPOSITION- Refine Technology, "The ATFâ„¢ System. Low shear separation", Product presentation, (20000000), pages 1 - 33, XP055341209-
OPPOSITION- GRAMER M.J. et al., "Antibody Production by a Hybridoma Cell Line at High Cell Density Is Limited by Two Independent Mechanisms", Biotechnology and Bio- engineering, (20020805), vol. 79, no. 3, pages 277 - 283, XP055450511
OPPOSITION- VOISARD D. et al., "Potential of Cell Retention Techniques for Large-Scale High- Density Perfusion Culture of Suspended Mammalian Cells", Biotechnology and Bioengineering, (20030630), vol. 82, no. 7, pages 751 - 765, XP002317548
OPPOSITION- PIRET et al., "Mammalian cell and protein distributions in ultrafiltration hollow fiber bioreactors", Biotech and Bioeng, (19901101), vol. 36, no. 9, pages 902 - 910, XP055039117
OPPOSITION- PIRET J. M. et al., "Mammalian Cell and Protein Distributions in Ultrafiltration Hollow Fiber Bioreactors", Biotechnology and Bioengineering, (19901101), vol. 36, no. 9, pages 902 - 910, XP055039117
OPPOSITION- GRAMER M. J. et al., "Effect of Harvesting Protocol on Performance of a Hollow Fiber Bioreactor", Biotechnology and Bioengineering, (19991105), vol. 65, no. 3, pages 334 - 340, XP055450512
OPPOSITION- TAKAZAWA et al., "High cell density perfusion culture of hybridoma cells recycling high molecular weight components", Cytotechnology, (19880200), vol. 1, no. 2, pages 171 - 178, XP008071522
OPPOSITION- TAKAZAWA Y. et al., "High cell density perfusion culture of hybridoma cells re- cycling high molecular weight components", Cytotechnology, (19880000), vol. 1, no. 2, pages 171 - 178, XP008071522
OPPOSITION- TAKAZAWA, Y. et al., "High cell density perfusion culture of hybridoma cells recycling high molecular weight components", Cytotechnology, (19880000), vol. 1, no. 2, pages 171 - 178, XP008071522
OPPOSITION- FLICKINGER et al., "Determination of specific monoclonal antibody secretion rateduring very slow hybridoma growth", Bioprocess Engineering, (19900000), vol. 5, no. 4, pages 155 - 164, XP055299549
OPPOSITION- FLICKINGER M. C. et al., "Determination of specific monoclonal antibody secre- tion rate during very slow hybridoma growth", Bioprocess Engineering, (19900000), vol. 5, no. 4, pages 155 - 164, XP055299549
OPPOSITION- FLICKINGER, MC et al., "Determination of specific monoclonal antibody secretion rate during very slow hybridoma growth", Bioprocess Engineering, (19900000), vol. 5, no. 4, pages 155 - 164, XP055299549
OPPOSITION- FRAHM et al., "Improvement of a mammalian cell culture process by adaptive,model-based dialysis fed-batch cultivation and suppression of apoptosis", Bioprocess Biosyst Eng, (20031100), vol. 26, no. 1, pages 1 - 10, XP002997132
OPPOSITION- FALKENBERG F. W. et al., "In vitro production of monoclonal antibodies in high concentration in a new and easy to handle modular minifermenter", Journal of Immunological Methods, Amsterdam, NL, (19950213), vol. 179, no. 1, pages 13 - 29, XP004021096
OPPOSITION- JACKSON L. R . et al., "Evaluation of hollow fiber bioreactors as an alternative to murine ascites production for small scale monoclonal antibody production", J ournal of Immunological Methods, Amster- dam, NL, (19960205), vol. 189, no. 2, pages 217 - 231, XP004020904
OPPOSITION- JACKSON L. R., "Evaluation of hollow fiber bioreactors as an alternative to murine ascites production for small scale monoclonal antibody production", Journal of Immunological Methods, (19960205), vol. 189, no. 2, pages 217 - 231, XP004020904
OPPOSITION- GRAMER M.J. et al., "Use of hollow fiber systems for rapid and direct scale up of antibody production from hybridoma cell lines cultured in CL-1000 flasks using BD Cell MAb medium", Cytotechnology, (20030700), vol. 42, no. 3, pages 155 - 162, XP019236798
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SEARCH- JAMES M. PIRET ET AL, "Mammalian cell and protein distributions in ultrafiltration hollow fiber bioreactors", BIOTECHNOLOGY AND BIOENGINEERING, (19901101), vol. 36, no. 9, doi:10.1002/bit.260360905, ISSN 0006-3592, pages 902 - 910, XP055039117 [A] 1-9 * the whole document *
SEARCH- FALKENBERG F W ET AL, "In vitro production of monoclonal antibodies in high concentration in a new and easy to handle modular minifermenter", JOURNAL OF IMMUNOLOGICAL METHODS, ELSEVIER SCIENCE PUBLISHERS B.V.,AMSTERDAM, NL, (19950213), vol. 179, no. 1, doi:10.1016/0022-1759(94)00266-Y, ISSN 0022-1759, pages 13 - 29, XP004021096 [A] 1-9 * the whole document *
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