IP Verse

Brip1 Variants Associated With Risk For Cancer - EP2681337

The patent EP2681337 was granted to Decode Genetics EHF on Apr 25, 2018. The application was originally filed on Mar 1, 2012 under application number EP12752998A. The patent is currently recorded with a legal status of "Granted And Under Opposition".

EP2681337

DECODE GENETICS EHF
Application Number
EP12752998A
Filing Date
Mar 1, 2012
Status
Granted And Under Opposition
Mar 23, 2018
Grant Date
Apr 25, 2018
External Links
Slate, Register, Google Patents

Patent Summary

Patent Family

Patent Family

Patent Oppositions

Patent oppositions filed by competitors challenge the validity of a granted patent. These oppositions are typically based on claims of prior art, lack of novelty, or non-obviousness. They are a key part of the process for determining a patent's strength and enforceability.

CompanyOpposition DateRepresentativeOpposition Status

Get instant alerts for new oppositions and patent status changes

KILGERJan 23, 2019CH KILGER ANWALTSPARTNERSCHAFT MBBWITHDRAWN

Patent Citations (4) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication NumberPublication Link
OPPOSITIONEP1716227
OPPOSITIONWO2007130534
OPPOSITIONWO2008035102
SEARCHWO2008035102

Non-Patent Literature (NPL) Citations (38) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference TextLink
DESCRIPTION- ALTSCHUL, S. ET AL., NUCLEIC ACIDS RES., (1997), vol. 25, pages 3389 - 3402-
DESCRIPTION- AMARZGUIOUI ET AL., FEBS LETT, (2005), vol. 579, pages 5974 - 81-
DESCRIPTION- BRUMMELKAMP ET AL., SCIENCE, (2002), vol. 296, pages 550 - 553-
DESCRIPTION- FIRE ET AL., NATURE, (1998), vol. 391, pages 806 - 11-
DESCRIPTION- KENT, W.J., GENOME RES., (2002), vol. 12, pages 656 - 64-
DESCRIPTION- KIM ET AL., NATURE BIOTECHNOL., (2005), vol. 23, pages 222 - 226-
DESCRIPTION- KIM; ROSSI, NATURE REV. GENET, (2007), vol. 8, pages 173 - 204-
DESCRIPTION- KIM; ROSSI, NATURE REV. GENET., (2007), vol. 8, pages 173 - 204-
DESCRIPTION- KRAUS, M.; AARONSON, S., METHODS ENZYMOL., (1991), vol. 200, pages 546 - 556-
DESCRIPTION- MARQUES ET AL., NATURE BIOTECHNOL., (2006), vol. 23, pages 559 - 565-
DESCRIPTION- NIELSEN, P. ET AL., SCIENCE, (1991), vol. 254, pages 1497 - 1500-
DESCRIPTION- SIOLAS ET AL., NATURE BIOTECHNOL., (2005), vol. 23, pages 227 - 231-
DESCRIPTION- THOMPSON, DRUG DISCOVERY TODAY, (2002), vol. 7, pages 912 - 917-
INTERNATIONAL-SEARCH-REPORT- BRADBURY AR ET AL., "Genetic susceptibility to breast cancer", REV ENDOCR METAB DISORD., (200709), vol. 8, no. 3, pages 255 - 267, XP027106316-
INTERNATIONAL-SEARCH-REPORT- JOHNATTY SE ET AL., "The BARD Cys557Ser polymorphism and breast cancer risk: an Australian case-control and family analysis", BREAST CANCER RES TREAT., (200905), vol. 115, no. 1, pages 145 - 150, XP019671243-
INTERNATIONAL-SEARCH-REPORT- RUTTER JL ET AL., "Mutational analysis of the BRCA1-interacting genes ZNF350/ZBRK1 and BRIP1/BACH1 among BRCA1 and BRCA2-negative probands from breast-ovarian cancer families and among early-onset breast cancer cases and reference individuals", HUM MUTAT., (200308), vol. 22, no. 2, pages 121 - 128, XP002467675
INTERNATIONAL-SEARCH-REPORT- BARROSO E ET AL., "The Fanconi anemia family of genes and its correlation with breast cancer susceptibility and breast cancer features", BREAST CANCER RES TREAT., (200912), vol. 118, no. 3, pages 655 - 660, XP019746629
INTERNATIONAL-SEARCH-REPORT- WONG MW ET AL., "BRIP1, PALB2, and RAD51C mutation analysis reveals their relative importance as genetic susceptibility factors for breast cancer", BREAST CANCER RES TREAT., (201106), vol. 127, no. 3, pages 853 - 859, XP055120608
INTERNATIONAL-SEARCH-REPORT- WALSH T ET AL., "Ten genes for inherited breast cancer", CANCER CELL., (200702), vol. 11, no. 2, pages 103 - 105, XP055120600
INTERNATIONAL-SEARCH-REPORT- PENNINGTON KP ET AL., "Hereditary ovarian cancer: beyond the usual suspects", GYNECOL ONCOL., (201202), vol. 124, no. 2, pages 347 - 353, XP028445105
INTERNATIONAL-SEARCH-REPORT- RAFNAR T ET AL., "Mutations-in BRIP1 confer high risk of ovarian cancer", NAT GENET., (20111002), vol. 43, no. 11, pages 1104 - 1107, XP055120607
INTERNATIONAL-SEARCH-REPORT- RAY AM ET AL., "Absence of truncating BRIP1 mutations in chromosome 17q-linked hereditary prostate cancer families", BR J CANCER., (20091215), vol. 101, no. 12, pages 2043 - 2047, XP055120612
INTERNATIONAL-SEARCH-REPORT- KARPPINEN SM ET AL., "Nordic collaborative study of the BARD1 Cys557Ser allele in 3956 patients with cancer: enrichment in familial BRCA1/BRCA2 mutation-negative breast cancer but not in other malignancies", J MED GENET., (200611), vol. 43, no. 11, pages 856 - 862, XP055120597
INTERNATIONAL-SEARCH-REPORT- REBBECK TR ET AL., "Modification of BRCA1-Associated Breast and Ovarian Cancer Risk by BRCA1-Interacting Genes", CANCER RES., (20110901), vol. 71, no. 17, pages 5792 - 5805, XP055120603
INTERNATIONAL-SEARCH-REPORT- DE NICOLO A ET AL., "A novel breast cancer-associated BRIP1 (FANCJ/BACH1) germ-line mutation impairs protein stability and function", CLIN CANCER RES., (20080715), vol. 14, no. 14, pages 4672 - 4680, XP055120596
INTERNATIONAL-SEARCH-REPORT- VAHTERISTO P ET AL., "BACH1 Ser919Pro variant and breast cancer risk", BMC CANCER., (20060124), vol. 6, page 19, XP021004869
INTERNATIONAL-SEARCH-REPORT- KUUSISTO KM ET AL., "Screening for BRCA1, BRCA2, CHEK2, PALB2, BRIP1, RAD50, and CDH1 mutations in high-risk Finnish BRCA1/2-founder mutation-negative breast and/or ovarian cancer individuals", BREAST CANCER RES., (20110228), vol. 13, no. 1, page R20, XP021099291
INTERNATIONAL-SEARCH-REPORT- SONG H ET AL., "Tagging single nucleotide polymorphisms in the BRIP1 gene and susceptibility to breast and ovarian cancer", PLOS ONE., (20070307), vol. 2, no. 3, page E268, XP055120599
OPPOSITION- WALSH et al., "Detection of inherited mutations for breast and ovarian cancer using genomic capture and massively parallel sequencing", PNAS, (20100713), vol. 107, no. 28, pages 12629 - 12633, XP055128035
OPPOSITION- REBBECK et al., "Modification of ovarian cancer risk by BRCA1/2-interacting genes in a multicenter cohort of BRCA1/2 mutation carriers", Cancer Research, (20090715), vol. 69, no. 14, pages 5801 - 5810, XP055163986
OPPOSITION- TAN et al., "PPM1D is a potential therapeutic target in ovarian clear cell carcinomas", Clin. Cancer Res., (20090401), vol. 15, no. 7, pages 2269 - 2280, XP055409324
OPPOSITION- DIMOVA et al., "Genomic markers for ovarian cancer at chromosomes 1, 8 and 17 revealed by array CGH analysis", Tumori, (20090000), vol. 95, pages 357 - 366, XP055553541
OPPOSITION- SONG et al., "Tagging single nucleotide polymorphisms in the BRIP1 gene and susceptibility to breast and ovarian cancer", PLoS One, (20070300), vol. 2, no. 3, pages 1 - 7, XP055120599
OPPOSITION- SCHILDKRAUT et al., "Association between DNA damage response and repair genes and risk of invasive serous ovarian cancer", PLoS One, (20100400), vol. 5, no. 4, pages 1 - 9, XP055230252
SEARCH- THORUNN RAFNAR ET AL, "Mutations in BRIP1 confer high risk of ovarian cancer", NATURE GENETICS, (20111002), vol. 43, no. 11, doi:10.1038/ng.955, ISSN 1061-4036, pages 1104 - 1107, XP055120607 [XP] 1-15 * the whole document *
SEARCH- MIKI Y ET AL, "A STRONG CANDIDATE FOR THE BREAST AND OVARIAN CANCER SUSCEPTIBILITY GENE BRCA1", SCIENCE, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE, US, (19941007), vol. 266, doi:10.1126/SCIENCE.7545954, ISSN 0036-8075, pages 66 - 71, XP000202410 [I] 1,2,4-9,11-15 * abstract *
SEARCH- T. R. REBBECK ET AL, "Modification of Ovarian Cancer Risk by BRCA1/2-Interacting Genes in a Multicenter Cohort of BRCA1/2 Mutation Carriers", CANCER RESEARCH, (20090707), vol. 69, no. 14, doi:10.1158/0008-5472.CAN-09-0625, ISSN 0008-5472, pages 5801 - 5810, XP055163986 [I] 1,2,4-9,11-15 * abstract *
SEARCH- A. DE NICOLO ET AL, "A Novel Breast Cancer-Associated BRIP1 (FANCJ/BACH1) Germ-line Mutation Impairs Protein Stability and Function", CLINICAL CANCER RESEARCH, (20080715), vol. 14, no. 14, doi:10.1158/1078-0432.CCR-08-0087, ISSN 1078-0432, pages 4672 - 4680, XP055120596 [A] 1-15 * the whole document *

Download Citation Report

Get a free citation report including examiner, opposition, and international search citations.

Get Citation Report

Dossier Documents

The dossier documents provide a comprehensive record of the patent’s prosecution history - including filings, correspondence, and decisions made by patent offices - and are crucial for understanding the patent’s legal journey and any challenges it may have faced during examination.

  • Date

    Description

  • Get instant alerts for new documents