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Prodrugs Of Phosphonate Nucleotide Analogues And Methods For Selecting And Making Same - EP2682397

The patent EP2682397 was granted to Gilead Sciences on Apr 19, 2017. The application was originally filed on Jul 20, 2001 under application number EP13164300A. The patent is currently recorded with a legal status of "Revoked".

EP2682397

GILEAD SCIENCES
Application Number
EP13164300A
Filing Date
Jul 20, 2001
Status
Revoked
Jan 17, 2025
Grant Date
Apr 19, 2017
External Links
Slate, Register, Google Patents

Patent Summary

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Patent Family

Patent Oppositions (3)

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GEORG KALHAMMERSTEPHAN TEIPELJan 19, 2018-ADMISSIBLE
AECHTERJan 17, 2018TER MEER STEINMEISTER & PARTNERADMISSIBLE
COOKEJan 17, 2018ELKINGTON AND FIFEADMISSIBLE

Patent Citations (33) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication NumberPublication Link
DESCRIPTIONEP0654037
DESCRIPTIONEP0821690
DESCRIPTIONUS4659825
DESCRIPTIONUS4724233
DESCRIPTIONUS4808716
DESCRIPTIONUS5130427
DESCRIPTIONUS5142051
DESCRIPTIONUS5202433
DESCRIPTIONUS5302585
DESCRIPTIONUS5352786
DESCRIPTIONUS5386030
DESCRIPTIONUS5434298
DESCRIPTIONUS5434299
DESCRIPTIONUS5476938
DESCRIPTIONUS5498752
DESCRIPTIONUS5650510
DESCRIPTIONUS5663159
DESCRIPTIONUS5688778
DESCRIPTIONUS5696263
DESCRIPTIONUS5733896
DESCRIPTIONUS5744600
DESCRIPTIONUS5798340
DESCRIPTIONUS5977061
DESCRIPTIONUSRE35919E
OPPOSITIONUS5476938
OPPOSITIONUS5739314
OPPOSITIONUS5977089
OPPOSITIONWO0035460
OPPOSITIONWO9804569
OPPOSITIONWO9904774
OTHERUS5739314
SEARCHUS5977089
SEARCHWO0035460

Non-Patent Literature (NPL) Citations (36) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference TextLink
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OPPOSITION- BARREIRA TERESA et al., "Standard molar enthalpies of formation of Mg and Ca alkoxides", Eur. J. Inorg. Chem., (20000000), pages 987 - 991, XP003029300-
OPPOSITION- BARREIRA TERESA et al., "Standard molar enthalpies of formation of Mg and Ca alkoxides", EUROPEAN JOURNAL OF INORGANIC CHEMISTRY, WEINHEIM, DE, (20000101), ISSN 1434-1948, pages 987 - 991, XP003029300-
OPPOSITION- Collier's Encyclopedia, (19660000), vol. 9, pages 35 - 40, XP055456188-
OPPOSITION- Hiromitsu Masada; Doi Y Et Al, "A New Heterogeneous Williamson Synthesis of Ethers Using t-Alkyl Substrates", J. Chem. Soc. Jap., (19960000), no. 3, pages 275 - 282, XP055456185-
OPPOSITION- MASADA et al., "A New Heterogeneous Williamson Synthesis of Ethers Using t-Alkyl Substrates", J. Chem. Soc. Jap., (19960000), no. 3, pages 275 - 282, XP055456185-
OPPOSITION- JI-MAO LIN et al., "Synthesis of Benzyl/Allyl Alkyl Ethers from Corresponding Magnesium Alkoxides", Tetrahedron Letters, (19960000), vol. 37, no. 29, pages 5159 - 5160, XP004029615
OPPOSITION- LIN J. M. et al., "Synthesis of Benzyl/Allyl Alkyl Ethers from Corresponding Magnesium Alkoxides", Tetrahedron Letters, (19960715), vol. 37, no. 29, pages 5159 - 5160, XP004029615
OPPOSITION- L. M. SCHULTZE et al., "Practical Synthesis of the anti-HIV Drug, PMPA", Tetrahedron Letters, (19980402), vol. 39, pages 1853 - 1856, XP004109567
OPPOSITION- SCHULTZE et al., "Practical Synthesis of the anti-HIV Drug, PMPA", Tetrahedron Letters, (19980000), vol. 39, pages 1853 - 1856, XP004109567
OPPOSITION- D. L. RILEY et al., "An Improved Process for the Preparation of Tenofovir Disoproxil Fumarate", Org Process Res Dev, (20160000), vol. 20, pages 742 - 750, XP055596964
OPPOSITION- MASCARENHAS C M et al., "Simple metal alkoxides as effective catalysts for the Hetero-Aidol-Tishchenko reaction", ORGANIC LETTERS, (19990101), vol. 1, no. 9, ISSN 1523-7060, pages 1427 - 1429, XP003029301
OPPOSITION- RICHARD H. YU et al., "PROCESS OPTIMIZATION IN THE SYNTHESIS OF 9- not 2-(DIETHYLPHOSPHONOMETHOXY)ETHYL 3/4 ADENINE: REPLACEMENT OF SODIUM HYDRIDE WITH SODIUM TERT-BUTOXIDE AS THE BASE FOR OXYGEN ALKYLATION", Organic Process Research & Development, (19990000), vol. 3, no. 1, pages 53 - 55, XP001097187
OPPOSITION- YU R. et al., "Process Optimization in the Synthesis of 9-[2- (Diethylphosphonomethoxy)ethyl]adenine: Replacement of Sodium Hydride with Sodium tert-Butoxide as the Base for Oxygen Alkylation", Org Proc Res Dev, (19990000), vol. 3, no. 1, pages 53 - 55, XP001097187
OPPOSITION- NISHIYAMA T. et al., "Ether Synthesis Using Trifluoromethanesulfonic Anhydride or Triflates Under Mild Reaction Conditions", Canadian Journal Of Chemistry, (19990000), vol. 77, pages 258 - 262, XP003035268
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OTHER- NISHIYAMA T. ET AL., "ETHER SYNTHESIS USING TRIFLUOROMETHANESULFONIC ANHYDRIDE OR TRIFLATES UNDER MILD REACTION CONDITIONS", CANADIAN JOURNAL OF CHEMISTRY, (1999), vol. 77, pages 258 - 262, XP003035268
SEARCH- BARREIRA TERESA ET AL, "Standard molar enthalpies of formation of Mg and Ca alkoxides", EUROPEAN JOURNAL OF INORGANIC CHEMISTRY, WILEY-VCH VERLAG, WEINHEIM, DE, (20000101), ISSN 1434-1948, pages 987 - 991, XP003029300 [A] 1 * the whole document *-
SEARCH- MASCARENHAS C M ET AL, "Simple metal alkoxides as effective catalysts for the Hetero-Aldol-Tishchenko reaction", ORGANIC LETTERS, AMERICAN CHEMICAL SOCIETY, US, (19990101), vol. 1, no. 9, ISSN 1523-7060, pages 1427 - 1429, XP003029301 [A] 1 * the whole document *

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