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Combinations Comprising Brexpiprazole Or A Salt Thereof And A Second Drug For Use In The Treatment Of A Cns Disorder - EP2694043

The patent EP2694043 was granted to Otsuka Pharmaceutical on Nov 1, 2017. The application was originally filed on Apr 4, 2012 under application number EP12719460A. The patent is currently recorded with a legal status of "Revoked".

EP2694043

OTSUKA PHARMACEUTICAL
Application Number
EP12719460A
Filing Date
Apr 4, 2012
Status
Revoked
Feb 21, 2020
Publication Date
Nov 1, 2017
External Links
Slate, Register, Google Patents

Patent Summary

Combining the drug 7-[4-(4-benzo[b]thiophen-4-yl-piperazin-1-yl)butoxy]-1H-quinolin-2-one (Compound (I)) with selective serotonin reuptake inhibitors (SSRIs) or serotonin and norepinephrine reuptake inhibitors (SNRIs) to improve antidepressant efficacy and reduce side effects compared to monotherapy with either drug. The combination targets multiple neurotransmitter systems for more comprehensive antidepressant action. It also enables lower dosing frequency due to sustained release properties of Compound (I).

Patent Family

Patent Family

Patent Oppositions (2)

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CompanyOpposition DateRepresentativeOpposition Status

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GENERICS UKAug 1, 2018ELKINGTON AND FIFEADMISSIBLE
ALFRED E TIEFENBACHERJul 31, 2018HAMM & WITTKOPPADMISSIBLE

Patent Citations (13) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication Number
DESCRIPTIONJP2008115172
DESCRIPTIONUS5178878
DESCRIPTIONUS6221392
DESCRIPTIONWO2006112464
INTERNATIONAL-SEARCH-REPORTJP2008115172
INTERNATIONAL-SEARCH-REPORTWO2004060374
INTERNATIONAL-SEARCH-REPORTWO2006112464
INTERNATIONAL-SEARCH-REPORTWO2009128537
OPPOSITIONEP1575590
OPPOSITIONJP2008115172
OPPOSITIONWO2004060374
OPPOSITIONWO2006112464
OPPOSITIONWO2009128537

Dossier Documents

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    Description

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