IP Verse

Composition And Methods Related To Modification Of 5-Methylcytosine (5Mc) - EP2694686

The patent EP2694686 was granted to The University OF Chicago on Jul 19, 2023. The application was originally filed on Apr 6, 2012 under application number EP12768638A. The patent is currently recorded with a legal status of "Patent Maintained As Amended".

EP2694686

THE UNIVERSITY OF CHICAGO
Application Number
EP12768638A
Filing Date
Apr 6, 2012
Status
Patent Maintained As Amended
Jun 16, 2023
Grant Date
Jul 19, 2023
External Links
Slate, Register, Google Patents

Patent Summary

Patent Family

Patent Family

Patent Oppositions

Patent oppositions filed by competitors challenge the validity of a granted patent. These oppositions are typically based on claims of prior art, lack of novelty, or non-obviousness. They are a key part of the process for determining a patent's strength and enforceability.

CompanyOpposition DateRepresentativeOpposition Status

Get instant alerts for new oppositions and patent status changes

AVIDITYAug 22, 2018AVIDITY -

Patent Citations (6) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication NumberPublication Link
DESCRIPTIONWO2011US31370-
DESCRIPTIONWO2010037001
DESCRIPTIONWO2011127136
INTERNATIONAL-SEARCH-REPORTWO2011025819
OPPOSITIONWO2010037001
SEARCHWO2010037001

Non-Patent Literature (NPL) Citations (122) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference TextLink
DESCRIPTION- BECK, NAT. BIOTECHNOL., (2010), vol. 28, pages 1026 - 1028-
DESCRIPTION- BECK; RAKYAN, TRENDS GENET., (2008), vol. 24, pages 231 - 237-
DESCRIPTION- BERMAN ET AL., NAT. GENET., (2012), vol. 44, pages 40 - 46-
DESCRIPTION- BERNSTEIN ET AL., CELL, (2007), vol. 128, pages 669 - 681-
DESCRIPTION- BIRD, GENES DEV., (2002), vol. 16, pages 6 - 21-
DESCRIPTION- BIRD, J. MOL. BIOL., (2011), vol. 409, pages 47 - 53-
DESCRIPTION- BOCK, EPIGENOMICS, (2009), vol. 1, pages 99 - 110-
DESCRIPTION- BOCK ET AL., NAT. BIOTECHNOL., (2010), vol. 28, pages 1106 - 1114-
DESCRIPTION- BOYSEN ET AL., J. CHROMATOGR. B ANALYT. TECHNOL. BIOMED. LIFE SCI., (2010), vol. 878, page 375-
DESCRIPTION- CHAVEZ ET AL., GENOME RES., (2010), vol. 20, pages 1441 - 1450-
DESCRIPTION- CHEN; RIGGS, J. BIOL. CHEM., (2011), vol. 286, pages 18347 - 18353-
DESCRIPTION- CLARK ET AL., NUCLEIC ACIDS RES., (1994), vol. 22, pages 2990 - 2997-
DESCRIPTION- COKUS ET AL., NATURE, (2008), vol. 452, pages 215 - 219-
DESCRIPTION- CORTELLINO ET AL., CELL, (2011), vol. 146, pages 67 - 79-
DESCRIPTION- DAI; HE, ORG. LETT., (2011), vol. 13, pages 3446 - 3449-
DESCRIPTION- DAWLATY ET AL., CELL. STEM CELL, (2011), vol. 9, pages 166 - 175-
DESCRIPTION- DEATON; BIRD, GENES DEV., (2011), vol. 25, pages 1010 - 1022-
DESCRIPTION- DE CARVALHO ET AL., TRENDS CELL BIOL., (2010), vol. 20, pages 609 - 617-
DESCRIPTION- DONNELLY ET AL., PROTEIN EXPR. PURIF., (2006), vol. 47, no. 2, pages 446 - 454-
DESCRIPTION- DOWN ET AL., NAT. BIOTECHNOL., (2008), vol. 26, pages 779 - 785-
DESCRIPTION- ESTELLER; ABERRANT, ANNU. REV. PHARMACOL. TOXICOL., (2005), vol. 45, pages 629 - 656-
DESCRIPTION- ESTELLER, NAT. REV. GENET., (2007), vol. 8, pages 286 - 298-
DESCRIPTION- EVANS, AUSTRAL. J. CHEM., (2007), vol. 60, no. 6, pages 384 - 395-
DESCRIPTION- FEINBERG; TYCKO, NAT. REV. CANCER, (2004), vol. 4, pages 143 - 153-
DESCRIPTION- FEINBERG; VOGELSTEIN, NATURE, (1983), vol. 301, pages 89 - 92-
DESCRIPTION- FICZ ET AL., NATURE, (2011), vol. 473, pages 398 - 402-
DESCRIPTION- FRAUER ET AL., PLOS ONE, (2011), vol. 6, page E21306-
DESCRIPTION- FROMMER ET AL., PROC. NATL. ACAD. SCI. USA, (1992), vol. 89, pages 1827 - 1831-
DESCRIPTION- GEIER; MODRICH, J. BIOL. CHEM., (1979), vol. 254, pages 1408 - 1413-
DESCRIPTION- GLOBISCH ET AL., PLOS ONE, (2010), vol. 5, page E15367-
DESCRIPTION- GOLL; BESTOR, ANNU. REV. BIOCHEM., (2005), vol. 74, pages 481 - 514-
DESCRIPTION- GU ET AL., NATURE, (2011), vol. 477, pages 606 - 610-
DESCRIPTION- GUO ET AL., CELL, (2011), vol. 145, pages 423 - 434-
DESCRIPTION- HARRIS ET AL., NAT. BIOTECHNOL., (2010), vol. 28, pages 1097 - 1105-
DESCRIPTION- HAWKINS ET AL., CELL. STEM CELL, (2010), vol. 6, pages 479 - 491-
DESCRIPTION- HE ET AL., SCIENCE, (2011), vol. 333, pages 1303 - 1307-
DESCRIPTION- HEIN ET AL., PHARMACEUT. RES., (2008), vol. 25, no. 10, pages 2216 - 2230-
DESCRIPTION- HON ET AL., GENOME RES., (2012), vol. 22, pages 246 - 258-
DESCRIPTION- HSU ET AL., BIOINFORMATICS, (2006), vol. 22, pages 1036 - 1046-
DESCRIPTION- HUANG ET AL., NUCLEIC ACIDS RES., (1982), vol. 10, page 1579-
DESCRIPTION- HUANG ET AL., PLOS ONE, (2010), vol. 5, page E8888-
DESCRIPTION- INOUE; ZHANG, SCIENCE, (2011), vol. 334, page 194-
DESCRIPTION- IQBAL ET AL., PROC. NATL. ACAD. SCI. USA, (2011), vol. 108, pages 3642 - 3647-
DESCRIPTION- ITO ET AL., NATURE, (2010), vol. 466, pages 1129 - 1133-
DESCRIPTION- ITO ET AL., NATURE LETTERS, (2010), vol. 266, no. 7310, pages 1129 - 1133-
DESCRIPTION- ITO ET AL., SCIENCE, (2011), vol. 333, pages 1300 - 1303-
DESCRIPTION- JACINTO ET AL., BIOTECHNIQUES, (2008), vol. 44, page 35,37,39-
DESCRIPTION- JAENISCH; BIRD, NAT. GENET., (2003), vol. 33, pages 245 - 254-
DESCRIPTION- JIN ET AL., NUCLEIC ACIDS RES., (2010), vol. 38, page E125-
DESCRIPTION- JONES; BAYLIN, NAT. REV. GENET., (2002), vol. 3, pages 415 - 428-
DESCRIPTION- JOSSE; KORNBERG, BIOL. CHEM., (1962), vol. 237, pages 1968 - 1976-
DESCRIPTION- KENT ET AL., GENOME RES., (2002), vol. 12, pages 996 - 1006-
DESCRIPTION- KO ET AL., NATURE, (2010), vol. 468, pages 839 - 843-
DESCRIPTION- KOH ET AL., CELL. STEM CELL, (2011), vol. 8, pages 200 - 213-
DESCRIPTION- KOLB ET AL., ANGEW. CHEM. INT. ED., (2001), vol. 40, pages 2004 - 2021-
DESCRIPTION- KRIAUCIONIS; HEINTZ, SCIENCE, (2009), vol. 324, pages 929 - 930-
DESCRIPTION- KUKUSHKIN ET AL., COORD. CHEM. REV., (1999), vol. 181, page 147-
DESCRIPTION- LANGMEAD ET AL., GENOME BIOL., (2009), vol. 10, page R25-
DESCRIPTION- LAW; JACOBSEN, NAT. REV. GENET., (2010), vol. 11, pages 204 - 220-
DESCRIPTION- LI ET AL., BIOINFORMATICS, (2009), vol. 25, pages 2078 - 2079-
DESCRIPTION- LISTER ET AL., CELL, (2008), vol. 133, pages 523 - 536-
DESCRIPTION- LISTER ET AL., NATURE, (2009), vol. 462, pages 315 - 322-
DESCRIPTION- LISTER ET AL., NATURE, (2011), vol. 471, pages 68 - 73-
DESCRIPTION- LORSBACH ET AL., LEUKEMIA, (2003), vol. 17, pages 637 - 641-
DESCRIPTION- MAITI; DROHAT, J. BIOL. CHEM., (2011), vol. 286, pages 35334 - 35338-
DESCRIPTION- MARGULIES ET AL., NATURE, (2005), vol. 437, pages 376 - 380-
DESCRIPTION- MARINUS; MORRIS, J. BACTERIOL., (1973), vol. 114, pages 1143 - 1150-
DESCRIPTION- MAY; HATTMAN, J. BACTERIOL., (1975), vol. 123, pages 768 - 770-
DESCRIPTION- MEISSNER ET AL., NATURE, (2008), vol. 454, pages 766 - 770-
DESCRIPTION- MEISSNER, NAT. BIOTECHNOL., (2010), vol. 28, pages 1079 - 1088-
DESCRIPTION- MEYER ET AL., CHEM, BIO. CHEM., (2003), vol. 4, pages 610 - 614-
DESCRIPTION- MISHINA; HE, J. AM. CHEM. SOC., (2003), vol. 125, pages 8730 - 8731-
DESCRIPTION- MOSES; MOORHOUSE, CHEM. SOC. REV., (2007), pages 1249 - 1262-
DESCRIPTION- MUNZEL ET AL., ANGEW CHEM. INT. ED. ENGL., (2010), vol. 49, pages 5375 - 5377-
DESCRIPTION- MYERS ET AL., PLOS BIOL., (2011), vol. 9, page E1001046-
DESCRIPTION- ONO ET AL., CANCER RES., (2002), vol. 62, pages 4075 - 4080-
DESCRIPTION- PASTOR ET AL., NATURE, (2011), vol. 473, pages 394 - 397-
DESCRIPTION- PELIZZOLA; ECKER, FEBS LTRS., (2011), vol. 585, pages 1994 - 2000-
DESCRIPTION- PFAFFENEDER ET AL., ANGEW CHEM. INT. ED ENGL., (2011), vol. 50, pages 7008 - 7012-
DESCRIPTION- QUENNEVILLE ET AL., MOL. CELL, (2011), vol. 44, pages 361 - 372-
DESCRIPTION- ROBERTSON ET AL., NAT. PROTOC., (2012), vol. 7, pages 340 - 350-
DESCRIPTION- ROBERTSON ET AL., NUCLEIC ACIDS RES., (2011), vol. 39, page E55-
DESCRIPTION- SCHUEBEL ET AL., PLOS GENET., (2007), vol. 3, pages 1709 - 1723-
DESCRIPTION- SIEGFRIED; CEDAR, CURR. BIOL., (1997), vol. 7, pages 305 - 307-
DESCRIPTION- SIEPEL ET AL., GENOME RES., (2005), vol. 15, pages 1034 - 1050-
DESCRIPTION- SONG ET AL., NAT. BIOTECHNOL., (2011), vol. 29, pages 68 - 72-
DESCRIPTION- SONG ET AL., NAT. METHODS, (2012), vol. 9, pages 75 - 77-
DESCRIPTION- SONG ET AL., NATURE BIOTECHNOLOGY, (2011), vol. 29, no. 1, pages 68 - 72-
DESCRIPTION- STADLER ET AL., NATURE, (2011), vol. 480, pages 490 - 495-
DESCRIPTION- STROUD ET AL., GENOME BIOL., (2011), vol. 12, page R54-
DESCRIPTION- SZULWACH ET AL., NAT. NEUROSCI., (2011), vol. 14, pages 1607 - 1616-
DESCRIPTION- SZULWACH ET AL., PLOS GENET., (2011), vol. 7, page E1002154-
DESCRIPTION- SZWAGIERCZAK ET AL., NUCLEIC ACIDS RES., (2010), vol. 38, page E181-
DESCRIPTION- TAHILIANI ET AL., SCIENCE, (2009), vol. 324, pages 930 - 935-
DESCRIPTION- TANABE ET AL., J. AM. CHEM. SOC., (2007), vol. 129, pages 8034 - 8040-
DESCRIPTION- TORNOE ET AL., J. ORGANIC CHEM., (2002), vol. 67, no. 9, pages 3057 - 3064-
DESCRIPTION- VALINLUCK ET AL., NUCLEIC ACIDS RES., (2004), vol. 32, pages 4100 - 4108-
DESCRIPTION- WEBER ET AL., NATURE GENETICS, (2005), vol. 37, pages 853 - 862-
DESCRIPTION- WIGLER ET AL., CELL, (1981), vol. 24, pages 33 - 40-
DESCRIPTION- WILLIAMS ET AL., ANAL. BIOCHEM., (1981), vol. 114, page 73-
DESCRIPTION- WILLIAMS ET AL., NATURE, (2011), vol. 473, pages 343 - 348-
DESCRIPTION- WOSSIDLO ET AL., NAT. COMMUN., (2011), vol. 2, page 241-
DESCRIPTION- WU ET AL., GENES DEV., (2011), vol. 25, pages 679 - 684-
DESCRIPTION- WU; ZHANG, GENES DEV., (2011), vol. 25, pages 2436 - 2452-
DESCRIPTION- XU ET AL., MOL. CELL, (2011), vol. 42, pages 451 - 464-
DESCRIPTION- YILDIRIM ET AL., CELL, (2011), vol. 147, pages 1498 - 1510-
DESCRIPTION- ZESCHNIGK ET AL., HUM. MOL. GENET., (1997), vol. 6, pages 387 - 395-
DESCRIPTION- ZHANG ET AL., GENOME BIOL., (2008), vol. 9, page R137-
DESCRIPTION- ZHANG ET AL., NATURE CHEM. BIOL., (2012), vol. 8, pages 328 - 330-
INTERNATIONAL-SEARCH-REPORT- SONG ET AL., "Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine.", NATURE-BIOTECHNOLOGY., (201101), vol. 29, no. 1, pages 68 - 72, XP055012325
INTERNATIONAL-SEARCH-REPORT- OKAZAKI ET AL., "Prediction of the Coding Sequences of Mouse Homologues of KIAA Gene: III.", THE COMPLETE NUCLEOTIDE SEQUENCES OF 500 MOUSE KIAA-HOMOLOGOUS CDNAS IDENTIFIED BY SCREENING OF TERMINAL SEQUENCES OF CDNA CLONES RANDOMLY SAMPLED FROM SIZE-FRACTIONATED LIBRARIES. DNA RESEARCH., (200308), vol. 10, no. 4, pages 167 - 180, XP002983736
INTERNATIONAL-SEARCH-REPORT- TAHILIANI ET AL., "Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by the MLL Partner TET1.", SCIENCE., (20090515), vol. 324, no. 5929, pages 1 - 24, XP002545640
OPPOSITION- GLOBISCH et al., "Tissue Distribution of 5-Hydroxymethylcytosine and Search for Active Demethylation Intermediates", PloS One, (20100000), vol. 5, no. 12, page e15367-
OPPOSITION- PRIVAT et al., "Photochemical Deamination and Dcmethylation of 5-Methykytosine", Chem. Res. Toxicol, (19960000), vol. 9, pages 745 - 750, XP055516216-
OPPOSITION- SHINSUKE et al., "Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification", Nature, (20100000), vol. 466, no. 7310, pages 1129 - 1133, XP055092131
OPPOSITION- SONG et al., "Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine", Nature Biotechnology, (20110000), vol. 29, no. 1, pages 68 - 72, XP055012325
OPPOSITION- WU et al., "Active DNA demethylation: many roads lead to Rome", Nat. Rev. Mol. Cell, (20100000), vol. 11, no. 9, pages 607 - 620, XP009162759
OPPOSITION- SIMMONS et al., "Fe11/a-ketoglutarate hydroxylases involved in nucleobase,nucleoside, nucleotide, and chromatin metabolism", Dalton Trans., (20080000), vol. 14, no. 38, pages 5132 - 5142, XP055516205
OPPOSITION- ITO et al., "Tet Proteins Can Convert 5-Methylcytosine to 5-Formylcytosine and 5-Carboxylcytosine", Science, (20110000), vol. 333, no. 6047, pages 1300 - 1303, XP055101432
OPPOSITION- GLOBISCH et al., "Tissue Distribution of 5-Hydroxymethylcytosine and Search for Active Demethylation Intermediates", PloS One, (20100000), vol. 5, no. 12, page e15367, XP055094345
SEARCH- SHINSUKE ITO ET AL, "Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification", NATURE, (20100718), vol. 466, no. 7310, doi:10.1038/nature09303, ISSN 0028-0836, pages 1129 - 1133, XP055092131 [A] 1-10 * the whole document *
SEARCH- SONG ET AL., "Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine.", NATURE-BIOTECHNOLOGY., (201101), vol. 29, no. 1, pages 68 - 72, XP055012325 [A] 6-9 * the whole document *

Download Citation Report

Get a free citation report including examiner, opposition, and international search citations.

Get Citation Report

Dossier Documents

The dossier documents provide a comprehensive record of the patent’s prosecution history - including filings, correspondence, and decisions made by patent offices - and are crucial for understanding the patent’s legal journey and any challenges it may have faced during examination.

  • Date

    Description

  • Get instant alerts for new documents