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Methods For The Treatment Of Breast Cancer - EP2751267

The patent EP2751267 was granted to Syndax Pharmaceuticals on Jan 24, 2018. The application was originally filed on Aug 31, 2012 under application number EP12827061A. The patent is currently recorded with a legal status of "Revoked".

EP2751267

SYNDAX PHARMACEUTICALS
Application Number
EP12827061A
Filing Date
Aug 31, 2012
Status
Revoked
Jul 3, 2020
Publication Date
Jan 24, 2018
External Links
Slate, Register, Google Patents

Patent Summary

Combination therapy for treating breast cancer that combines an HDAC inhibitor (entinostat) with an aromatase inhibitor (exemestane) to enhance treatment efficacy and overcome resistance. The therapy involves monitoring protein lysine acetylation levels in patients, with continued treatment recommended if acetylation levels increase after 15 days of therapy. The combination is particularly effective in patients with hormone receptor-positive breast cancer that has progressed on prior aromatase inhibitor therapy.

Patent Family

Patent Family

Patent Oppositions (2)

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CompanyOpposition DateRepresentativeOpposition Status

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HEXALOct 24, 2018ELKINGTON AND FIFE -
GENERICS UKOct 23, 2018TER MEER STEINMEISTER & PARTNER -

Patent Citations (8) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication Number
DESCRIPTIONUS2009048156
DESCRIPTIONWO2008154382
INTERNATIONAL-SEARCH-REPORTUS2009048156
INTERNATIONAL-SEARCH-REPORTUS2010092992
INTERNATIONAL-SEARCH-REPORTUS2010305167
OPPOSITIONUS2009048156
OPPOSITIONWO2008154382
SEARCHWO2008154382

Dossier Documents

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    Description

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