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Rapid Method For Cloning And Expression Of Cognate Antibody Variable Region Gene Segments - EP2794652

The patent EP2794652 was granted to F Hoffmann LA Roche on Nov 15, 2017. The application was originally filed on Dec 19, 2012 under application number EP12812945A. The patent is currently recorded with a legal status of "Opposition Rejected".

EP2794652

F HOFFMANN LA ROCHE
Application Number
EP12812945A
Filing Date
Dec 19, 2012
Status
Opposition Rejected
Apr 3, 2020
Grant Date
Nov 15, 2017
External Links
Slate, Register, Google Patents

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UCB BIOPHARMAAug 15, 2018J A KEMPADMISSIBLE

Patent Citations (8) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication Number
DESCRIPTIONUS2006051348
DESCRIPTIONUS2007269868
DESCRIPTIONWO2007031550
DESCRIPTIONWO2008045140
DESCRIPTIONWO2008144763
DESCRIPTIONWO2010056898
INTERNATIONAL-SEARCH-REPORTWO2010056898
OPPOSITIONWO2011147903

Non-Patent Literature (NPL) Citations (7) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference Text
OPPOSITION- Leila FARAHMAND et al., "Ligation Independent Cloning of Polycistronic, Genetically Modified, HuMAb4DS-8 F (ab') 2, in Bacterial Plasmid", Avicenna Journal of Medical Biotechnology, (20120101), vol. 4, no. 1, pages 15 - 22, XP055514418
OPPOSITION- Liao H X et al., "High-throughput isolation of immunoglobulin genes from single human B cells and expression as monoclonal antibodies", Journal of Virological Methods, (20090601), vol. 158, no. 1-2, pages 171 - 179, XP026022553
OPPOSITION- Thomas Tiller, "Single B cell antibody technologies", New Biotechnology, (20110901), vol. 28, no. 5, pages 453 - 457, XP028290739
OPPOSITION- LI MAMIE Z; ELEDGE STEPHEN J, "Harnessing homologous recombination in vitro to generate recombinant DNA via SLIC", Nature Methods, (20070211), vol. 4, no. 3, pages 251 - 256, XP002564746
OPPOSITION- Nobuyuki Kurosawa; Megumi Yoshioka; Masaharu Isobe, "Target-selective homologous recombination cloning for high-throughput generation of monoclonal antibodies from single plasma cells", BMC Biotechnology, (20110413), vol. 11, no. 1, pages 1 - 8, XP021097757
OPPOSITION- Frank Thieme, Carola Engler, Romy Kandzia, Sylvestre Marillonnet, "Quick and Clean Cloning: A Ligation-Independent Cloning Strategy for Selective Cloning of Specific PCR Products from Non-Specific Mixes", PLOS ONE, (20110601), vol. 6, no. 6, pages e20556-1 - e20556-12, XP055514402
OPPOSITION- Stefan Seeber et al.,, "A Robust High Throughput Platform to Generate Functional Recombinant Monoclonal Antibodies Using Rabbit B Cells from Peripheral Blood", PLOS ONE, (20140201), vol. 9, no. 2, pages e86184-1 - e86184-14, XP055128871

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