IP Verse

Animal Models And Therapeutic Molecules - EP2798950

The patent EP2798950 was granted to Kymab on Mar 22, 2023. The application was originally filed on Jul 7, 2010 under application number EP14170196A. The patent is currently recorded with a legal status of "Patent Maintained As Amended".

EP2798950

KYMAB
Application Number
EP14170196A
Filing Date
Jul 7, 2010
Status
Patent Maintained As Amended
Feb 17, 2023
Grant Date
Mar 22, 2023
External Links
Slate, Register, Google Patents

Patent Summary

Patent Family

Patent Family

Patent Oppositions

Patent oppositions filed by competitors challenge the validity of a granted patent. These oppositions are typically based on claims of prior art, lack of novelty, or non-obviousness. They are a key part of the process for determining a patent's strength and enforceability.

CompanyOpposition DateRepresentativeOpposition Status

Get instant alerts for new oppositions and patent status changes

REGENERON PHARMACEUTICALSJan 18, 2018J A KEMPADMISSIBLE

Patent Citations (15) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication NumberPublication Link
DESCRIPTIONUS5859307
DESCRIPTIONWO0104288
DESCRIPTIONWO2007117410
DESCRIPTIONWO2010039900
DESCRIPTIONWO9929837
OPPOSITIONEP2480676
OPPOSITIONUS6596541
OPPOSITIONUS7294754
OPPOSITIONWO02066630
OPPOSITIONWO2011163314
SEARCHUS2006015957
SEARCHWO02066630
SEARCHWO2007117410
SEARCHWO2008070367
SEARCHWO2011163311

Non-Patent Literature (NPL) Citations (33) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference TextLink
DESCRIPTION- CHAN, W.; COSTANTINO, N.; LI, R.; LEE, S.C.; SU, Q.; MELVIN, D.; COURT, D.L.; LIU, P., "A recombineering based approach for high-throughput conditional knockout targeting vector construction", NUCLEIC ACIDS RESEARCH, (2007), vol. 35, page E64-
DESCRIPTION- CHUNG, Y.J.; JONKERS, J.; KITSON, H.; FIEGLER, H.; HUMPHRAY, S.; SCOTT, C.; HUNT, S.; YU, Y.; NISHIJIMA, I.; VELDS, A. ET AL., "A whole-genome mouse BAC microarray with 1-Mb resolution for analysis of DNA copy number changes by array comparative genomic hybridization", GENOME RESEARCH, (2004), vol. 14, pages 188 - 196-
DESCRIPTION- JANEWAY; TRAVERS, Immunobiology-
DESCRIPTION- OSOEGAWA K ET AL., GENOME RESEARCH, (2001), vol. 11, pages 483 - 496-
DESCRIPTION- PASQUALINI; ARAP, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, (2004), vol. 101, pages 257 - 259-
DESCRIPTION- ZHENG ET AL., NAR, (1999), vol. 27, no. 11, pages 2354 - 2360-
DESCRIPTION- RAMIREZ-SOLIS, R.; DAVIS, A.C.; BRADLEY, A., "Gene targeting in embryonic stem cells", METHODS IN ENZYMOLOGY, (1993), vol. 225, doi:doi:10.1016/0076-6879(93)25054-6, pages 855 - 878, XP000918540
DESCRIPTION- WALLACE, H.A.C. ET AL., "Manipulating the mouse genome to engineering precise functional syntenic replacements with human sequence", CELL, (2007), vol. 128, doi:doi:10.1016/j.cell.2006.11.044, pages 197 - 209, XP002481713
DESCRIPTION- ADAMS DJ; QUAIL MA; COX T; VAN DER WEYDEN L; GORICK BD; SU Q; CHAN WI; DAVIES R; BONFIELD JK; LAW F, "A genome-wide, end-sequenced 129Sv BAC library resource for targeting vector construction", GENOMICS, (20051027), vol. 86, no. 6, doi:doi:10.1016/j.ygeno.2005.08.003, pages 753 - 8, XP005265840
DESCRIPTION- SCHLAKE, T.; J. BODE, "Use of mutated FLP-recognition-target-(FRT-)sites for the exchange of expression cassettes at defined chromosomal loci", BIOCHEMISTRY, (1994), vol. 33, doi:doi:10.1021/bi00209a003, pages 12746 - 12751, XP000616165
DESCRIPTION- RAMIREZ-SOLIS R; LIU P; BRADLEY A, "Chromosome engineering in mice", NATURE, (1995), vol. 378, no. 6558, doi:doi:10.1038/378720a0, pages 720 - 4, XP001026456
DESCRIPTION- BARRETT, M.T.; SCHEFFER, A.; BEN-DOR, A.; SAMPAS, N.; LIPSON, D.; KINCAID, R.; TSANG, P.; CURRY, B.; BAIRD, K.; MELTZER, P.S. ET A, "Comparative genomic hybridization using oligonucleotide microarrays and total genomic DNA", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, (2004), vol. 101, doi:doi:10.1073/pnas.0407979101, pages 17765 - 17770, XP002630628
DESCRIPTION- LIANG, Q.; CONTE, N.; SKARNES, W.C.; BRADLEY, A., "Extensive genomic copy number variation in embryonic stem cells", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, (2008), vol. 105, doi:doi:10.1073/pnas.0805638105, pages 17453 - 17456, XP055303731
DESCRIPTION- PROSSER, H.M. ET AL., "Mosaic complementation demonstrates a regulatory role for myosin V a in actin dynamics of Stereocilia", MOL. CELL. BIOL., (2008), vol. 28, doi:doi:10.1128/MCB.01282-07, pages 1702 - 12, XP003031390
DESCRIPTION- PROSSER, H.M.; RZADZINSKA, A.K.; STEEL, K.P.; BRADLEY, A., "Mosaic complementation demonstrates a regulatory role for myosin V a in actin dynamics of stereocilia", MOLECULAR AND CELLULAR BIOLOGY, (2008), vol. 28, doi:doi:10.1128/MCB.01282-07, pages 1702 - 1712, XP003031390
OPPOSITION- CARTER et al., "Standardized Nomenclature for Inbred Strains of Mice", Cancer Research, (19520000), vol. 12, no. 8, pages 602 - 613, XP055344294-
OPPOSITION- EPPIG et al., "Guidelines for Nomenclature of Mouse and Rat Strains", (20110000), URL: www.informatics.jax.org/mgihome/nomen/strains.shtml, XP055344298-
OPPOSITION- MACDONALD et al., "VELOCIGENE TECHNOLOGY EXTENDED TO HUMANIZATION OF SEVERAL MEGABASES OF COMPLEX GENE LOCI", Abstract 21 from 1st International MUGEN conference on Animal Models, Athens, Greece, (20060000), XP055304452-
OPPOSITION- MACDONALD et al., "VELOCIGENE TECHNOLOGY EXTENDED TO HUMANIZATION OF SEVERAL MEGABASES OF COMPLEX GENE LOCI", Abstract corresponding to the Poster of D8a, (20060000), XP055343742-
OPPOSITION- "Printout of PDF", University of California, URL: http://www.research.uci.edu/facilities-services/tmf/presentations/Mouse_ES_CellLine.pdf-
OPPOSITION- STEVENS et al., "Veloclmmune - A novel platform", Pharma Focus Asia, (20080000), vol. 8, pages 72 - 74, XP055455618-
OPPOSITION- STEVENS et al., "Veloclmmune: Humanization of immunoglobulin loci using VelociGene® technology", 1st International MUG EN conference on Animal Models, Athens, Greece, (20060000), XP055455647-
OPPOSITION- STEVENS et al., "Veloclmmune: Humanization of immunoglobulin loci using VelociGene® technology", Poster from 1st International MUGEN conference on Animal Models, Athens Greece, (20060910), XP055455639-
OPPOSITION- FESTING et al., "Revised nomenclature for strain 129 mice", Mammalian Genome, (19990000), vol. 10, page 836, XP055344303
OPPOSITION- MURPHY et al., "Veloclmmune: Immunoglobulin Variable Region Humanized Mice", MURPHY et al., Melvyn Little et al, Recombinant Antibodies for Immunotherapy, (20090000), pages 100 - 107, ISBN 9780521887328, XP055343725
OPPOSITION- BECK et al., "Genealogies of mouse inbred strains", Nature Genetics, (20000000), vol. 24, pages 23 - 25, XP055343752
OPPOSITION- SIMPSON et al., "Genetic variation among 129 substrains and its importance for targeted mutagenesis in mice", Nature Genetics, (19970000), vol. 16, pages 19 - 27, XP008033035
OPPOSITION- CHIA et al., "The origins and uses of mouse outbred stocks", Nature Genetics, (20050000), vol. 37, no. 11, pages 1181 - 1186, XP055344306
OPPOSITION- MACDONALD et al., "Precise and in situ genetic humanization of 6 Mb of mouse immunoglobulin genes", PNAS USA, (20140000), vol. 111, no. 14, pages 5147 - 5152, XP055126064
OPPOSITION- MURPHY et al., "Mice with megabase humanization of their immunoglobulin genes generate antibodies as efficiently as normal mice", PNAS USA, (20140000), vol. 111, no. 14, pages 5153 - 5158, XP055162338
OPPOSITION- MARTINEZ et al., "The Mouse (Mus musculus) Immunoglobulin Kappa Variable (IGKV) Genes and Joining (IGKJ) Segments", Exp. Clin. Immunogenet., (19980000), vol. 15, pages 184 - 193, XP055344312
OPPOSITION- RETTER et al., "Sequence and Characterization of the Ig Heavy Chain Constant and Partial Variable Region of the Mouse Strain 129S1", J. Immunol., (20070000), vol. 179, no. 4, pages 2419 - 2427, XP055268136
OTHER- SEAN STEVENS, "HUMAN ANTIBODY DISCOVERY VELOCIMMUNE-A NOVEL PLATFORM", PHARMA FOCUS ASIA, (2008), no. 8, pages 72 - 74, XP003035947-

Download Citation Report

Get a free citation report including examiner, opposition, and international search citations.

Get Citation Report

Dossier Documents

The dossier documents provide a comprehensive record of the patent’s prosecution history - including filings, correspondence, and decisions made by patent offices - and are crucial for understanding the patent’s legal journey and any challenges it may have faced during examination.

  • Date

    Description

  • Get instant alerts for new documents