The patent EP2858679 was granted to Ethris on Jun 5, 2024. The application was originally filed on Jun 7, 2013 under application number EP13800103A. The patent is currently recorded with a legal status of "Patent Maintained As Amended".

Patent oppositions filed by competitors challenge the validity of a granted patent. These oppositions are typically based on claims of prior art, lack of novelty, or non-obviousness. They are a key part of the process for determining a patent's strength and enforceability.
Patent citations refer to prior patents cited during different phases such as opposition or international search.
| Citation Phase | Publication Number | 
|---|---|
| DESCRIPTION | EP20100742089 | 
| DESCRIPTION | EP2459231 | 
| DESCRIPTION | US2008286834 | 
| DESCRIPTION | US2009286852 | 
| DESCRIPTION | US2012027803 | 
| DESCRIPTION | US4373071 | 
| DESCRIPTION | US4401796 | 
| DESCRIPTION | US4415732 | 
| DESCRIPTION | US4458066 | 
| DESCRIPTION | US4500707 | 
| DESCRIPTION | US4668777 | 
| DESCRIPTION | US4897355 | 
| DESCRIPTION | US4973679 | 
| DESCRIPTION | US5047524 | 
| DESCRIPTION | US5132418 | 
| DESCRIPTION | US5153319 | 
| DESCRIPTION | US5171678 | 
| DESCRIPTION | US5262530 | 
| DESCRIPTION | US5334761 | 
| DESCRIPTION | US5700642 | 
| DESCRIPTION | US5744335 | 
| DESCRIPTION | US5780014 | 
| DESCRIPTION | US5885613 | 
| DESCRIPTION | WO2005121348 | 
| DESCRIPTION | WO2008052770 | 
| DESCRIPTION | WO2010042877 | 
| DESCRIPTION | WO2010053572 | 
| DESCRIPTION | WO2011068810 | 
| DESCRIPTION | WO2012170889 | 
| DESCRIPTION | WO2012170930 | 
| INTERNATIONAL-SEARCH-REPORT | US2002192651 | 
| INTERNATIONAL-SEARCH-REPORT | US2004224912 | 
| INTERNATIONAL-SEARCH-REPORT | US2005158302 | 
| INTERNATIONAL-SEARCH-REPORT | US2009286852 | 
| INTERNATIONAL-SEARCH-REPORT | US2011244026 | 
| INTERNATIONAL-SEARCH-REPORT | WO2006016097 | 
| INTERNATIONAL-SEARCH-REPORT | WO2010056403 | 
| INTERNATIONAL-SEARCH-REPORT | WO9810748 | 
| OPPOSITION | WO2012006376 | 
| OPPOSITION | WO2012006377 | 
| OPPOSITION | WO2012006378 | 
| OPPOSITION | WO2012170930 | 
| SEARCH | WO9312756 | 
NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.
| Citation Phase | Reference Text | 
|---|---|
| OPPOSITION | - Andries Oliwia, Marina De Filette, Joanna Reiman, Stefaan C. De Smedt, Jo Demeester, Mario Van Poucke, Luc Peelman, Cindy Peleman, Tony Lahoutte, Niek N. Sanders, "Comparison of the Gene Transfer Efficiency of mRNA/GL67 and pDNA/GL67 Complexes in Respiratory Cells", Molecular Pharmaceutics, (20120607), pages 2136 - 2145, XP055883653 | 
| OPPOSITION | - Anonymous, "Cystic Fibrosis", National Institute of Health, (19951101), pages 1 - 6, XP055883645 | 
| OPPOSITION | - Anonymous, "UniProtKB - P07988 (PSPB_HUMAN)", Database Uniprot KB, (20210929), pages 1 - 1, Database Uniprot KB, URL: https://www.uniprot.org/uniprot/P07988, (20220125), XP055883553 | 
| OPPOSITION | - Anonymous, "Uniprot KB Q16637", Database Uniprot KB, (20210929), pages 1 - 1, Database Uniprot KB, URL: https:/ /www.uniprot.org/uniprot/Q16637, (20220125), XP055883662 | 
| OPPOSITION | - Ma Feihe, Liu Yang, Zhuorui Sun, Jinjin Chen, Xuehui Rui, Zachary Glass, Qiaobing Xu, "Neurotransmitter-derived lipidoids (NT-iipidoids)for enhanced brain delivery through intravenous injection", Science Advances, (20200701), vol. 6, no. 30, page eabb4429, XP055883656 | 
| OPPOSITION | - Mays L. E., Leon Gustafsson, Renate Koch, Eva Muellerhermelink, Markus Mezger, Rupert Handgretinger, Dominik Hartl, Michael S. D. Kormann., "Chemically Modified mRNA Encoding mFoxp3 Protects Against Airway Inflammation in a Murine Model of Allergic Asthma", Molecular Therapy, (20120501), vol. 20, no. 102, pages S42 - S43, XP055883620 | 
| OPPOSITION | - Rubin, Staddon, "THE CELL BIOLOGY OF THE BLOOD-BRAIN BARRIER", Annu Rev Neurosci, (19990101), vol. 22, pages 11 - 28, XP055883658 | 
| OPPOSITION | - Vieira W. A., Pretorius E., "The impact of asthma on the gastrointestinal tract (GIT)", Journal of Astham and Allergy, (20100101), vol. 3, pages 123 - 130, XP055883556 | 
| OPPOSITION | - Wilder M. A., Msn, Rng, C-Nnp, "Surfactant Protein B Deficiency in Infants With Respiratory Failure", J Permat Neonat Nurs, (20040101), vol. 18, no. 1, pages 61 - 67, XP055883639 | 
| OPPOSITION | - Amir K. Varkouhi; Marije Scholte; Gert Storm; Hidde J. Haisma;, "Endosomal escape pathways for delivery of biologicals", Journal of Controlled Release, Elsevier, AMSTERDAM, NL, AMSTERDAM, NL , (20101019), vol. 151, no. 3, doi:10.1016/j.jconrel.2010.11.004, ISSN 0168-3659, pages 220 - 228, XP028215423 | 
| OPPOSITION | - Michael S D Kormann, Günther Hasenpusch, Manish K Aneja, Gabriela Nica, Andreas W Flemmer, Susanne Herber-Jonat, Marceline Huppmann, Lauren E Mays, Marta Illenyi, Andrea Schams, Matthias Griese, Iris Bittmann, Rupert Handgretinger, Dominik Hartl, Joseph Rosenecker, Carsten Rudolph, "Expression of therapeutic proteins after delivery of chemically modified mRNA in mice", Nature Biotechnology, Gale Group Inc., (20110201), vol. 29, no. 2, doi:10.1038/nbt.1733, ISSN 10870156, pages 154 - 157, XP055040839 | 
| OPPOSITION | - Lorenzi Julio CC; Trombone Ana PF; Rocha Carolina D; Almeida Luciana P; Lousada Ricardo L; Malardo Thiago; Fontoura Isabela C; Rossetti Renata AM; Gembre Ana F; Silva Aristóbolo M; Silva Celio L; Coelho-Castelo Arlete AM, "Intranasal vaccination with messenger RNA as a new approach in gene therapy: Use against tuberculosis", BMC Biotechnology, BioMed Central Ltd, (20101020), vol. 10, no. 1, doi:10.1186/1472-6750-10-77, ISSN 1472-6750, page 77, XP021076472 | 
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French translation of claims
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German translation of the claims
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Letter accompanying subsequently filed items
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Reply to Written Opinion prepared by the EPO
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European search opinion
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Supplementary European search report
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Search started
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Communication to designated inventor
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Information on entry into European phase
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Converted Sequence Listing
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Copy of the international search report
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Dec 12, 2013
Published international application - A1
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