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Methods, Cells And Organisms - EP2877571

The patent EP2877571 was granted to Kymab on May 30, 2018. The application was originally filed on Sep 18, 2014 under application number EP14772198A. The patent is currently recorded with a legal status of "Revoked".

EP2877571

KYMAB
Application Number
EP14772198A
Filing Date
Sep 18, 2014
Status
Revoked
Oct 29, 2021
Grant Date
May 30, 2018
External Links
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REGENERON PHARMACEUTICALSFeb 27, 2019WITTHOFF JAEKEL STEINECKE PATENTANWALTE PARTG MBBADMISSIBLE

Patent Citations (14) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication NumberPublication Link
EXAMINATIONWO2013061078
EXAMINATIONWO2013176772
EXAMINATIONWO2014093622
OPPOSITIONUS2011119779
OPPOSITIONUS2012204278
OPPOSITIONUS2013095565
OPPOSITIONWO2011146121
OPPOSITIONWO2013061078
OPPOSITIONWO2013176772
OPPOSITIONWO2014093622
OPPOSITIONWO2014191518
OTHERWO2011146121
OTHERWO2013176772
OTHERWO2014093622

Non-Patent Literature (NPL) Citations (46) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference TextLink
EXAMINATION- DANIEL J DICKINSON ET AL, "Engineering the Caenorhabditis elegans genome using Cas9-triggered homologous recombination", HHS PUBLIC ACCESS AUTHOR MANUSCRIPT, GB, (20130901), vol. 10, no. 10, doi:10.1038/nmeth.2641, ISSN 1548-7091, pages 1028 - 1034, XP055340980
EXAMINATION- DANIEL J DICKINSON ET AL, "Engineering the Caenorhabditis elegans genome using Cas9-triggered homologous recombination", HHS PUBLIC ACCESS AUTHOR MANUSCRIPT, GB, (20130901), vol. 10, no. 10, doi:10.1038/nmeth.2641, ISSN 1548-7091, pages 1028 - 1034, XP055340984
EXAMINATION- YOU-TZUNG CHEN ET AL, "PiggyBac Transposon-Mediated, Reversible Gene Transfer in Human Embryonic Stem Cells", STEM CELLS AND DEVELOPMENT, NL, (20100601), vol. 19, no. 6, doi:10.1089/scd.2009.0118, ISSN 1547-3287, pages 763 - 771, XP055248208
EXAMINATION- W. FUJII ET AL, "Efficient generation of large-scale genome-modified mice using gRNA and CAS9 endonuclease", NUCLEIC ACIDS RESEARCH, GB, (20130830), vol. 41, no. 20, doi:10.1093/nar/gkt772, ISSN 0305-1048, pages e187 - e187, XP055270998
EXAMINATION- S. KONDO ET AL, "Highly Improved Gene Targeting by Germline-Specific Cas9 Expression in Drosophila", GENETICS, US, (20130903), vol. 195, no. 3, doi:10.1534/genetics.113.156737, ISSN 0016-6731, pages 715 - 721, XP055248203
EXAMINATION- HAGEN RICHTER ET AL, "Exploiting CRISPR/Cas: Interference Mechanisms and Applications", INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, (20130712), vol. 14, no. 7, doi:10.3390/ijms140714518, pages 14518 - 14531, XP055153313
INTERNATIONAL-SEARCH-REPORT- ANN RAN F ET AL, "Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity", CELL, CELL PRESS, US, vol. 154, no. 6, doi:10.1016/J.CELL.2013.08.021, ISSN 0092-8674, (20130912), pages 1380 - 1389, (20130829), XP002718603 [X] 1-22,24-28,34-40,70 * the whole document * [I] 23,29-33
INTERNATIONAL-SEARCH-REPORT- GAJ THOMAS ET AL, "ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering", TRENDS IN BIOTECHNOLOGY, ELSEVIER PUBLICATIONS, CAMBRIDGE, GB, (20130509), vol. 31, no. 7, doi:10.1016/J.TIBTECH.2013.04.004, ISSN 0167-7799, pages 397 - 405, XP028571313 [AD] 1-40,70 * the whole document *
INTERNATIONAL-SEARCH-REPORT- WOONG Y HWANG ET AL, "Efficient genome editing in zebrafish using a CRISPR-Cas system", NATURE BIOTECHNOLOGY, (20130129), vol. 31, no. 3, doi:10.1038/nbt.2501, ISSN 1087-0156, pages 227 - 229, XP055086625 [A] 1-40,70 * the whole document *
INTERNATIONAL-SEARCH-REPORT- PATRICK D HSU ET AL, "DNA targeting specificity of RNA-guided Cas9 nucleases", NATURE BIOTECHNOLOGY, NATURE PUBLISHING GROUP, UNITED STATES, vol. 31, no. 9, doi:10.1038/NBT.2647, ISSN 1546-1696, (20130901), pages 827 - 832, (20130721), XP002718604 [X] 1-5,7,9-22,24-27,35-40,70 * the whole document *
INTERNATIONAL-SEARCH-REPORT[ ] - PATRICK D HSU ET AL, "Supplementary Information: DNA targeting specificity of RNA-guided Cas9 nuclease, Supplementary Methods", NATURE BIOTECHNOLOGY, NATURE PUBLISHING GROUP, UNITED STATES, vol. 31, no. 9, doi:10.1038/NBT.2647, ISSN 1546-1696, (20130901), pages 1 - 26, (20130721), XP002718605 [ ] * the whole document *
INTERNATIONAL-SEARCH-REPORT[ ] - CONG L ET AL, "Supplementary Material to : Multiplex Genome Engineering Using CRISPR/Cas Systems", SCIENCE, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE, US, (20130103), vol. 339, no. 6121, doi:10.1126/SCIENCE.1231143, ISSN 0036-8075, pages 819 - 823, XP002730884 [ ] * the whole document *
INTERNATIONAL-SEARCH-REPORT- L. CONG ET AL, "Multiplex Genome Engineering Using CRISPR/Cas Systems", SCIENCE, (20130215), vol. 339, no. 6121, doi:10.1126/science.1231143, ISSN 0036-8075, pages 819 - 823, XP055067741 [XD] 1-7,9-22,24-27,35-40,70 * the whole document *
INTERNATIONAL-SEARCH-REPORT- HAGEN RICHTER ET AL, "Exploiting CRISPR/Cas: Interference Mechanisms and Applications", INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, (20130712), vol. 14, no. 7, doi:10.3390/ijms140714518, pages 14518 - 14531, XP055153313 [A] 1-40,70 * the whole document *
OPPOSITION- HARALD VON MELCHNER et al., "Engineering of ES cell genomes with recombinase systems", (20040101), vol. 1, pages 609 - 622, XP001206845-
OPPOSITION- Leslie A Pray et al, "Transposons: the jumping genes", Scitable by nature education, (20080000), pages 1 - 5, XP055575674-
OPPOSITION- MELCHNER et al., "Engineering of ES Cell Genomes with Recombinase Systems", Handbook of Stem Cells, (20040000), pages 609 - 622, XP001206845-
OPPOSITION- PRAY et al., "Transposons: The Jumping Genes", Nature Education, (20080000), vol. 1, no. 1, page 204, XP055575674-
OPPOSITION- TOUCHMAN, J., "Comparative Genomics", Nature Education Knowledge, vol. 3, no. 10, (20100000), page 13, URL: https://www.nature.com/scitable/knowledqe/library/comparative-qenomics-13239404, XP055624467-
OPPOSITION- BIRLING et al., "Site-Specific Recombinases for Manipulation of the Mouse Genome", Transgenesis Techniques, Methods in Molecular Biology, (20090000), vol. 561, pages 245 - 263, XP009121653
OPPOSITION- Marie-Christine Birling et al., "Chapter 16 - Site-Specific Recombinases for Manipulation of the Mouse Genome", DNA Repair Protocols. Methods in Molecular Biology, (20090101), pages 245 - 263, doi:10.1007/978-1-60327-019-9_16, XP009121653
OPPOSITION- Ann Ran F et al., "Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity", CELL,, (20130912), vol. 154, no. 6, doi:10.1016/j.cell.2013.08.021, pages 1380 - 1389, XP055299681
OPPOSITION- RAN et al., "Double Nicking by RNA-Guided CRISPR Cas9 for Enhanced Genome Editing Specificity", HHS Public Access Author Manuscript, (20130912), vol. 154, no. 6, pages 1 - 19, XP055575646
OPPOSITION- WIRTH et al., "Road to Precision: Recombinase-Based Targeting Technologies for Genome Engineering", Current Opinion in Biotechnology, (20070000), vol. 18, pages 411 - 419, XP022350911
OPPOSITION- Wirth et al., "Road to precision: recombinase-based targeting technologies for genome engineering", CURRENT OPINION IN BIOTECHNOLOGY, (20071001), vol. 18, no. 5, pages 411 - 419, XP022350911
OPPOSITION- TURAN et al., "Recombinase-Mediated Cassette Exchange (RMCE) _ A Rapidly- Expanding Toolbox for Targeted Genomic Modifications", Gene, (20120127), vol. 515, no. 1, pages 1 - 27, XP055383251
OPPOSITION- Soeren Turan et al., "Recombinase-Mediated Cassette Exchange (RMCE): Traditional Concepts and Current Challenges Recombinase-mediated cassette exchange (RMCE) — A rapidly-expanding toolbox for targeted genomic mo", Journal of Molecular Biology, (20110000), vol. 407, doi:10.1016/j.jmb.2011.01.004, pages 193 - 221, XP055575689
OPPOSITION- TURAN et al., "Recombinase-Mediated Cassette Exchange (RMCE): Traditional Concepts and Current Challenges", Journal of Molecular Biology, (20110000), vol. 407, pages 193 - 221, XP055575689
OPPOSITION- DICKINSON et al., "Engineering the Caenorhabditis Elegans Genome using Cas9-Triggered Homologous Recombination", HHS Public Access Author Manuscript, (20130901), vol. 10, no. 10, pages 1 - 18, XP055575643
OPPOSITION- DICKINSON et al., "Engineering the Caenorhabditis elegans Genome Using Cas9-Triggered Homologous Recombination", Nature Methods, (20130000), vol. 10, no. 10, doi:10.1038/nmeth.2641, XP055340980
OPPOSITION- MALEKI et al., "Application of phiC31 integrase system in stem cells biology and technology: a review", Frontiers in Life Science, (20180000), vol. 11, no. 1, pages 1 - 10, XP055624434
OPPOSITION- CHEN et al., "PiggyBac Transposon-Mediated , Reversible Gene Transfer in Human Embryonic Stem Cells", Stem Cell and Development, (20100601), vol. 19, no. 6, pages 763 - 771, XP055248208
OPPOSITION- You-Tzung Chen ET AL., "PiggyBac Transposon-Mediated, Reversible Gene Transfer in Human Embryonic Stem Cells", Stem Cells and Development, (20100601), vol. 19, no. 6, pages 763 - 771, XP055248208
OPPOSITION- FUJII et al., "Efficient Generation of Large-Scale Genome-Modified Mice using gRNA and Cas9 Endonuclease", Nucleic Acids Research, (20130830), vol. 41, no. 20, pages 1 - 9, XP055270998
OPPOSITION- Fujii W ET AL., "Efficient generation of large-scale genome-modified mice using gRNA and CAS9 endonuclease", Nucleic Acids Research, (20131101), vol. 41, no. 20, pages 1 - 9, XP055270998
OPPOSITION- CONG et al., "Multiplex Genome Engineering Using CRISPR/Cas systems", HHS Public Access Author Manuscript, (20130215), vol. 339, no. 6121, pages 1 - 9, XP055426395
OPPOSITION- Cong et al., "Supplementary Material to Multiplex Genome Engineering Using CRISPR/Cas systems", Science, (20130103), vol. 339, no. 6121, pages 1 - 28, XP002730884
OPPOSITION- Cong L et al., "Multiplex Genome Engineering Using CRISPR/Cas Systems", Science, (20130215), vol. 339, no. 6121, pages 819 - 823, XP055067741
OPPOSITION- GRATZ et al., "Genome Engineering of Drosophila with CRISPR RNA-Guided Cas9 Nuclease", Genetics, (20130800), vol. 194, pages 1029 - 1035, XP055102690
OPPOSITION- Gratz S J et al., "Genome Engineering of Drosophila with the CRISPR RNA-Guided Cas9 Nuclease", Genetics, (20130801), vol. 194, no. 4, pages 1029 - 1035, XP055102690
OPPOSITION- KONDO et al., "Highly Improved Gene Targeting by Germline-Specific Cas9 Expression in Drosophila", Genetics, (20130903), vol. 195, no. 3, pages 715 - 721, XP055248203
OPPOSITION- Kondo S et al., "Highly Improved Gene Targeting by Germline-Specific Cas9 Expression in Drosophila", GENETICS, (20131101), vol. 195, no. 3, pages 715 - 721, XP055248203
OPPOSITION- Hagen Richter et al., "Exploiting CRISPR/Cas: Interference Mechanisms and Applications", International Journal of Molecular Sciences, (20130712), vol. 14, no. 7, pages 14518 - 14531, XP055153313
OPPOSITION- RICHTER et al., "Exploiting CRISPR/Cas: Interference Mechanisms and Applications", International Journal of Molecular Sciences, (20130712), vol. 14, no. 7, pages 14518 - 14531, XP055153313
OTHER- CHEN, Y.T. et al., "PiggyBac Transposon-Mediated, Reversible Gene Transfer in Human Embryonic Stem Cells", Stem Cells Dev., (20100000), vol. 19, no. 6, pages 763 - 771, XP055248208
OTHER- KONDO, S.; UEDA, R., "Highly Improved Gene Targeting by Germline-Specific Cas9 Expression in Drosophila", Genetics, (20130903), vol. 195, no. 3, pages 715 - 721, XP055248203

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