IP Verse

Treatment Of Wolfram Syndrome-Related Neurodegeneration - EP2900236

The patent EP2900236 was granted to The University OF Birmingham on Sep 29, 2021. The application was originally filed on Sep 27, 2013 under application number EP13771198A. The patent is currently recorded with a legal status of "Patent Maintained As Amended".

EP2900236

THE UNIVERSITY OF BIRMINGHAM
Application Number
EP13771198A
Filing Date
Sep 27, 2013
Status
Patent Maintained As Amended
Aug 27, 2021
Grant Date
Sep 29, 2021
External Links
Slate, Register, Google Patents

Patent Summary

Patent Family

Patent Family

Patent Oppositions

Patent oppositions filed by competitors challenge the validity of a granted patent. These oppositions are typically based on claims of prior art, lack of novelty, or non-obviousness. They are a key part of the process for determining a patent's strength and enforceability.

CompanyOpposition DateRepresentativeOpposition Status

Get instant alerts for new oppositions and patent status changes

NEUROFIX SLOct 15, 2019MANUEL ILLESCAS Y ASOCIADOSADMISSIBLE

Patent Citations (8) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication Number
EXAMINATIONUS2007162989
INTERNATIONAL-SEARCH-REPORTUS2009249501
INTERNATIONAL-SEARCH-REPORTWO2009089011
INTERNATIONAL-SEARCH-REPORTWO2009137795
INTERNATIONAL-SEARCH-REPORTWO2013055834
INTERNATIONAL-SEARCH-REPORTWO2013112602
OPPOSITIONEP1435235
OPPOSITIONWO2005034737

Non-Patent Literature (NPL) Citations (20) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference Text
INTERNATIONAL-SEARCH-REPORT- AKIYAMA M ET AL, "Increased insulin demand promotes while pioglitazone prevents pancreatic beta cell apoptosis in Wfs1 knockout mice", DIABETOLOGIA, (200904), vol. 52, no. 4, ISSN 0012-186X, pages 653 - 663, XP002718417 [A] 1-15 * abstract *
INTERNATIONAL-SEARCH-REPORT- TERASMAA ANTON ET AL, "Wfs1 mutation makes mice sensitive to insulin-like effect of acute valproic acid and resistant to streptozocin", JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY, (201109), vol. 67, no. 3, pages 381 - 390, XP002718416 [A] 1-15 * abstract *
INTERNATIONAL-SEARCH-REPORT- YAMADA TAKAHIRO ET AL, "WFS1-deficiency increases endoplasmic reticulum stress, impairs cell cycle progression and triggers the apoptotic pathway specifically in pancreatic beta-cells", HUMAN MOLECULAR GENETICS, (200605), vol. 15, no. 10, pages 1600 - 1609, XP002718405 [A] 1-15 * abstract *
INTERNATIONAL-SEARCH-REPORT- GHARANEI SELEY ET AL, "Vacuolar-type H+-ATPase V1A subunit is a molecular partner of Wolfram syndrome 1 (WFS1) protein, which regulates its expression and stability", HUMAN MOLECULAR GENETICS, (201301), vol. 22, no. 2, pages 203 - 217, XP002718406 [AP] 1-15 * the whole document *
INTERNATIONAL-SEARCH-REPORT- KAKIUCHI CHIHIRO ET AL, "Valproate, a Mood Stabilizer, Induces WFS1 Expression and Modulates Its Interaction with ER Stress Protein GRP94", PLOS ONE, (200901), vol. 4, no. 1, ISSN 1932-6203, XP002718415 [A] 1-15 * page 3, column 1, lines 3-5 *
OPPOSITION- FERDINANDO DI CUNTO, "Inhibitory Function of p21 Cip1/WAF1 in Differentiation of Primary Mouse Keratinocytes Independent of Cell Cycle Control", Science, (19980515), vol. 280, no. 5366, pages 1069 - 1072, XP055646782
OPPOSITION- G Ali Qureshi et al, "chapter 1", Oxidative Stress and Neurodegenerative Disorders, (20070000), page 1, XP055646770
OPPOSITION- Jeung-Whan Han ET AL, "Activation of p21 WAFI/Cipl Transcription through Spl Sites by Histone Deacetylase Inhibitor Apicidin", J. Biol. Chem, (20010910), vol. 276, no. 45, pages 42084 - 42090, XP055646778
OPPOSITION- Mathias Ocker et al, "THE SYNTHETIC RETINOID ADAPALENE INHIBITS PROLIFERATION AND INDUCES APOPTOSIS IN COLORECTAL CANCER CELLS JN VITRO", Int. J. Cancer, (20030917), vol. 107, no. 3, pages 453 - 459, XP055646783
OPPOSITION- SELEY GHARANEI, "Study of Wolfram Syndrome in Neuronal Cell Models", thesis, (20130100), XP055646761
OPPOSITION- Shamim I. et al, "preface", Neurodegenerative Diseases, (20120312), page vii, XP055646768
OPPOSITION- Kaname Yoshizawa et al, Cancer, (20021100), vol. 95, no. 10, pages 2243 - 2251, XP055646773
OPPOSITION- Maria Laura Martin et al, "the role of membrane fatty acid remodeling in the antitumor mechanism of action of 2-hydroxyoleic acid", Biochim. Biophys. Acta, (20130127), vol. 1828, pages 1405 - 1413, XP055646762
OPPOSITION- silvia Teres, "2-Hydroxyoleate, a nontoxic membrane binding anticancer drug, induces glioma cell differentiation and autophagy", Proc. Natl. Acad. Sci. USA, (20120529), vol. 109, no. 22, pages 8489 - 8494, XP055646765
OPPOSITION- Oras Mistafa et al, J. Biol. Chem, (20100903), vol. 285, no. 36, pages 27900 - 27910, XP055646776
OPPOSITION- Gharanei S et al, "Vacuolar-type H+-ATPase V1A subunit is a molecular partner of Wolfram syndrome 1 (WFS1) protein, which regulates its expression and stability", Human Molecular Genetics, (20121003), vol. 22, no. 2, pages 203 - 217, XP002718406
OPPOSITION- Jordi Martinez, "The repression of E2F-1 is critical for the activity of minerval against cancer", J. Pharmacol. Exp. Ther., (20050714), vol. 315, no. 1, pages 466 - 474, XP002673918
OPPOSITION- Martinez Jordi et al, "Membrane structure modulation, protein kinase Calpha activation, and anticancer activity of Minerval", Molecular Pharmacology, (20050201), vol. 67, no. 2, pages 531 - 540, XP002673916
OPPOSITION- QIAN ET AL, "THE HISTONE DEACETYLASE INHIBITOR NVP-LAQ824 INHIBITS ANGIOGENESIS AND HAS A GREATER ANTITUMOR EFFECT IN COMBINATION WITH THE VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR TYROSINE KINASE INHIBITOR PTK787/ZK222584", Cancer Res., (20040915), vol. 64, no. 18, pages 6626 - 6634, XP008075089
OPPOSITION- Chihiro Kalkiuchi et al, "Valproate, a Mood Stabilizer, Induces WFS1 Expression and Modulates Its Interaction with ER Stress Protein GRP94", PLoS ONE, (20090106), vol. 4, no. 1, pages 1 - 6, XP002718415

Download Citation Report

Get a free citation report including examiner, opposition, and international search citations.

Get Citation Report

Dossier Documents

The dossier documents provide a comprehensive record of the patent’s prosecution history - including filings, correspondence, and decisions made by patent offices - and are crucial for understanding the patent’s legal journey and any challenges it may have faced during examination.

  • Date

    Description

  • Get instant alerts for new documents