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Methods For Producing A Population Of Pancreatic Beta-Cells - EP2900820

The patent EP2900820 was granted to Centre National DE LA Recherche Scientifique Cnrs on Nov 18, 2020. The application was originally filed on Sep 16, 2013 under application number EP13763241A. The patent is currently recorded with a legal status of "Patent Maintained As Amended".

EP2900820

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
Application Number
EP13763241A
Filing Date
Sep 16, 2013
Status
Patent Maintained As Amended
Oct 16, 2020
Grant Date
Nov 18, 2020
External Links
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DIAMYD MEDICALOct 26, 2018ZACCO SWEDENWITHDRAWN

Patent Citations (4) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication Number
INTERNATIONAL-SEARCH-REPORTUS2010166675
INTERNATIONAL-SEARCH-REPORTWO2011012707
OPPOSITIONWO2011012707
OPPOSITIONWO2012050907

Non-Patent Literature (NPL) Citations (15) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference Text
INTERNATIONAL-SEARCH-REPORT- COURTNEY M ET AL, "In vivo conversion of adult [alpha]-cells into [beta]-like cells: a new research avenue in the context of type 1 diabetes.", DIABETES, OBESITY & METABOLISM, (201110), vol. 13 Suppl 1, ISSN 1463-1326, pages 47 - 52, XP055054730 [A] 1-20 * the whole document *
INTERNATIONAL-SEARCH-REPORT- KORDOWICH S ET AL, "Reprogramming into pancreatic endocrine cells based on developmental cues", MOLECULAR AND CELLULAR ENDOCRINOLOGY, (20100708), vol. 323, no. 1, ISSN 0303-7207, pages 62 - 69, XP027243538 [Y] 1-3,6-14,17,18 * the whole document *
INTERNATIONAL-SEARCH-REPORT- SHIN OKAZAKI ET AL, "Aristaless-related homeobox gene disruption leads to abnormal distribution of GABAergic interneurons in human neocortex: evidence based on a case of X-linked lissencephaly with abnormal genitalia (XLAG)", ACTA NEUROPATHOLOGICA, (20080506), vol. 116, no. 4, ISSN 1432-0533, pages 453 - 462, XP019628815 [A] 1-20 * the whole document *
INTERNATIONAL-SEARCH-REPORT- SANGEETA DHAWAN ET AL, "Pancreatic Cell Identity Is Maintained by DNA Methylation-Mediated Repression of Arx", DEVELOPMENTAL CELL, (20110318), vol. 20, no. 4, doi:10.1016/J.DEVCEL.2011.03.012, ISSN 1534-5807, pages 419 - 429, XP028210833 [X] 1,2,7-9,13 * the whole document *
INTERNATIONAL-SEARCH-REPORT- N. SOLTANI ET AL, "GABA exerts protective and regenerative effects on islet beta cells and reverses diabetes", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, (20110627), vol. 108, no. 28, doi:10.1073/pnas.1102715108, ISSN 0027-8424, pages 11692 - 11697, XP055091542 [AD] 1-20 * the whole document *
INTERNATIONAL-SEARCH-REPORT- PATRICK COLLOMBAT ET AL, "Embryonic endocrine pancreas and mature [beta] cells acquire [alpha] and PP cell phenotypes upon Arx misexpression", JOURNAL OF CLINICAL INVESTIGATION, (20070402), vol. 117, no. 4, doi:10.1172/JCI29115, ISSN 0021-9738, pages 961 - 970, XP055055049 [AD] 1-20 * the whole document *
INTERNATIONAL-SEARCH-REPORT- A. S. HANCOCK ET AL, "Glucagon Deficiency Reduces Hepatic Glucose Production and Improves Glucose Tolerance In Adult Mice", MOLECULAR ENDOCRINOLOGY, (20100801), vol. 24, no. 8, doi:10.1210/me.2010-0120, ISSN 0888-8809, pages 1605 - 1614, XP055055047 [XD] 8,9 * the whole document *
INTERNATIONAL-SEARCH-REPORT- COLLOMBAT PATRICK ET AL, "THE SIMULTANEOUS LOSS OF ARX AND PAX4 GENES PROMOTES A SOMATOSTATIN-PRODUCING CELL FATE SPECIFICATION AT THE EXPENSE OF THE .ALPHA.- AND .BETA.-CELL LINEAGES IN THE MOUSE ENDOCRINE PANCREAS", DEVELOPMENT, (20050701), vol. 132, no. 13, doi:10.1242/DEV.01870, ISSN 0950-1991, pages 2969 - 2980, XP002545030 [AD] 1-20 * the whole document *
INTERNATIONAL-SEARCH-REPORT- MONICA COURTNEY ET AL, "The Inactivation of Arx in Pancreatic Î -Cells Triggers Their Neogenesis and Conversion into Functional Î2-Like Cells", PLOS GENETICS, (20131031), vol. 9, no. 10, doi:10.1371/journal.pgen.1003934, page e1003934, XP055091435
INTERNATIONAL-SEARCH-REPORT- FRIOCOURT GAELLE ET AL, "Mutations in ARX result in several defects involving GABAergic neurons", FRONTIERS IN CELLULAR NEUROSCIENCE, (201003), vol. 4, pages 1 - 11, XP002717611 [A] 1-20 * the whole document *
OPPOSITION- ACKERMAN et al., Cell Metabolism, (20181106), vol. 28, pages 1 - 6
OPPOSITION- Ben-Othmann, N et al, "Long-Term GABA Administration Induces Alpha Cell-Mediated Beta-like Cell Neogenesis", Cell , (20170112), vol. 168, no. 1-2, pages 73 - 85
OPPOSITION- COLLOMBAT et al., "Reprogramming into pancreatic endocrine cells based on developmental cues", Mol Cell Endocrinol, (20100000), vol. 323, pages 62 - 69, XP027052839
OPPOSITION- ACKERMAN et al., Cell Metabolism, (20181106), vol. 28, pages 1 - 6, XP085527188
OPPOSITION- SOLTANI et al., "GABA exerts protective and regenerative effects on islet beta cells and reverses diabetes", Proc Natl Acad Sci, (20110000), vol. 108, pages 11692 - 11697, XP055091542

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