Fgfr3 Fusion Gene And Pharmaceutical Drug Targeting Same - EP2902489

The patent EP2902489 was granted to Chugai Seiyaku Kabushiki Kaisha on Feb 7, 2018. The application was originally filed on Sep 27, 2013 under application number EP13842962A. The patent is currently recorded with a legal status of "Granted And Under Opposition".

EP2902489

CHUGAI SEIYAKU KABUSHIKI KAISHA
Application Number
EP13842962A
Filing Date
Sep 27, 2013
Status
Granted And Under Opposition
Aug 11, 2017
Grant Date
Feb 7, 2018
External Links
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MURPHYJun 13, 2018COOLEY UKADMISSIBLE

Patent Citations (42) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication NumberPublication Link
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OPPOSITIONEP2902489
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OPPOSITIONWO2013129369
SEARCHUS2010003258
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Non-Patent Literature (NPL) Citations (10) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference TextLink
OPPOSITION- AIKATERINI et al., "Morphological, Biological, and Biochemical Characteristics of HumanBladder Transitional Cell Carcinomas Grown in Tissue Culture andin Nude Mice", Cancer Research, (19840900), vol. 44, pages 3997 - 4005, XP055499855-
OPPOSITION- GUAGNANO et al., "Discovery of 3-(2,6-Dichloro-3,5-dimethoxy-phenyl)-1-{6-[4-(4-ethyl-piperazin-1-yl)-phenylamino]-pyrimidin-4-yl}-1-methyl-urea (NVP-BGJ398), A Potent and Selective Inhibitor of the Fibroblast Growth Factor Receptor Family of Receptor Tyrosine Kinase", J Med Chem., (20110921), vol. 54, no. 20, pages 7066 - 7083, XP002689272
OPPOSITION- LAMONT, "Small molecule FGF receptor inhibitors block FGFR-dependent urothelial carcinoma growth in vitro and in vivo", Brit J Cancer, (20101130), vol. 104, no. 1, pages 75 - 82, XP002683505
OPPOSITION- WILLIAMS et al., "Oncogenic FGFR3 gene fusions in bladder cancer", Hum Mol Genet, (20121121), vol. 22, no. 4, pages 795 - 803, XP055105338
OPPOSITION- WU et al., "Identification of Targetable FGFR Gene Fusions in Diverse Cancers", Cancer Discovery, (20130404), vol. 3, no. 6, pages 636 - 647, XP055123926
SEARCH[ ] - GUZMAN-ARANGUEZ ANA ET AL, "Fibroblast growth factor receptor 3 inhibition by small interfering RNAs in achondroplasia", ANALES DE LA REAL ACADEMIA NACIONAL DE FARMACIA, (2011), vol. 77, no. 1, ISSN 1697-4271(print), pages 4 - 11-
SEARCH- GUZMAN-ARANGUEZ ANA ET AL, "Fibroblast growth factor receptor 3 inhibition by small interfering RNAs in achondroplasia", BIOSIS, BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US, (2011), Database accession no. PREV201300548533, XP002743072 [X] 18 * abstract *-
SEARCH- WUECHNER CHRISTIANE ET AL, "Human fibroblast growth factor receptor 3 gene (IGFR3): Genomic sequence and primer set information for gene analysis", HUMAN GENETICS, SPRINGER, BERLIN, DE, (199701), vol. 100, no. 2, doi:10.1007/S004390050493, ISSN 0340-6717, pages 215 - 219, XP002452730 [X] 17,20 * abstract *
SEARCH- YU KATAOKA ET AL, "Foretinib (GSK1363089), a multi-kinase inhibitor of MET and VEGFRs, inhibits growth of gastric cancer cell lines by blocking inter-receptor tyrosine kinase networks", INVESTIGATIONAL NEW DRUGS ; THE JOURNAL OF NEW ANTICANCER AGENTS, KLUWER ACADEMIC PUBLISHERS, BO, (20110608), vol. 30, no. 4, doi:10.1007/S10637-011-9699-0, ISSN 1573-0646, pages 1352 - 1360, XP035079560 [X] 18 * abstract *
SEARCH- PRINOS PANAGIOTIS ET AL, "A common FGFR3 gene mutation in hypochondroplasia", HUMAN MOLECULAR GENETICS, (1995), vol. 4, no. 11, ISSN 0964-6906, pages 2097 - 2101, XP002743071 [X] 17,20 * abstract *

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