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Method Of Increasing Bone Toughness And Stiffness And Reducing Fractures - EP2907522

The patent EP2907522 was granted to ELI Lilly on Aug 2, 2017. The application was originally filed on Aug 19, 1999 under application number EP15152726A. The patent is currently recorded with a legal status of "Revoked".

EP2907522

ELI LILLY
Application Number
EP15152726A
Filing Date
Aug 19, 1999
Status
Revoked
Oct 11, 2019
Grant Date
Aug 2, 2017
External Links
Slate, Register, Google Patents

Patent Summary

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Patent Family

Patent Oppositions (3)

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GEDEON RICHTER RICHTER HELM BIOLOGICS RICHTER HELM BIOTECApr 27, 2018HAMM & WITTKOPPADMISSIBLE
STADA ARZNEIMITTELApr 27, 2018HAMM & WITTKOPPADMISSIBLE
TEVA PHARMACEUTICALSApr 27, 2018D YOUNGADMISSIBLE

Patent Citations (9) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication NumberPublication Link
DESCRIPTIONUS19970069075-
DESCRIPTIONUS19970069875-
DESCRIPTIONUS4086196
DESCRIPTIONUS5208041
DESCRIPTIONUS5556940
OPPOSITIONEP0920873
OPPOSITIONUS4698328
OTHEREP0920873
SEARCHUS4698328

Non-Patent Literature (NPL) Citations (41) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference TextLink
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OPPOSITION- li et al, "Parathyroid Hormone Stimulates Cancellous Bone Formationat Skeletal Sites Regardless of Marrow Composition inOvariectomized Rats", Bone, (19990000), vol. 24, no. 2, pages 95 - 100, XP055400090-
OPPOSITION- Li et al, "Parathyroid Hormone Stimulates Cancellous Bone Formation at Skeletal Sites Regardless of Marrow Composition in Ovariectomized Rats", Bone, (19990000), vol. 24, no. 2, pages 95 - 100, XP055400090-
OPPOSITION- NEER RM et al., "The use of parathyroid hormone plus 1,25-dihydroxyvitamin D to increase trabecular bone in osteoporotic men and postmenopausal women", Osteoporosis, (19870900), pages 829 - 835, XP002549387-
OPPOSITION- REID IR, "THE ROLES OF CALCIUM AND VITAMIN D IN THE PREVENTION OF OSTEOPOROSIS", Endocrinology and Metabolism Clinics, (19980600), vol. 27, no. 2, pages 389 - 398, XP055437974-
OPPOSITION- simmons et al, "Parathyroid Hormone (1-34) Increased Total Body Bone Mass in Aged Female Rats", The Journal of Pharmacology and Experimental Therapeutics, (19980000), vol. 286, no. 341, pages 341 - 344, XP055400093-
OPPOSITION- Simmons H A Et Al, "Parathyroid Hormone (1-34) Increased Total Body Bone Mass in Aged Female Rats", The Journal of Pharmacology and Experimental Therapeutics, (19980000), vol. 286, no. 341, pages 341 - 344, XP055400093-
OPPOSITION- WALKER-BONE K et al., "Is screening for osteoporosis worthwhile?", British Medial Bulletin, (19980000), vol. 54, no. 4, pages 915 - 927, XP055437969-
OPPOSITION- FINKELSTEIN J et al., "The use of parathyroid hormone plus 1,25-dihydroxyvitamin D to increase trabecular bone in osteoporotic men and postmenopausal women", JAMA, (19980923), vol. 280, no. 12, pages 1067 - 1073, XP000982932
OPPOSITION- SLOVIK DM et al., "Restoration of spinal bone in osteoporotic men by treatment with human parathyroid hormone (1-34) and 1,25-dihydroxyvitamin D", J Bone Miner Res, (19860000), vol. 1, pages 377 - 381, XP000981712
OPPOSITION- Reginster Et Al, "Treatment of Osteoporosis: Role of Bone-Forming Agents", Osteoporos. Int., (19990000), pages S91 - S96, XP055400070
OPPOSITION- Treatment of Osteoporosis: Role of Bone-Forming Agents, "Reginster et al", Osteoporos. Int., (19990000), pages S91 - S96, XP055400070
OPPOSITION- cosman et al, "Is Parathyroid Hormone a Therapeutic Option for Osteoporosis? A Review of the Clinical Evidence", Calcif Tissue Int., (19980000), vol. 62, pages 475 - 480, XP055400073
OPPOSITION- Peck, "Consensus Development Conference: Diagnosis, Prophylaxis, and Treatment of Osteoporosis", The American Journal of Medicine, (19930000), vol. 94, no. 6, pages 646 - 650, XP008017481
OPPOSITION- LINDSAY et al., "Randomised controlled study of effect of parathyroid hormone on vertebral-bone mass and fracture incidence among postmenopausal women on oestrogen with osteoporosis", The Lancet, (19970823), vol. 350, pages 550 - 555, XP002133428
OPPOSITION- NEER RM et al., "EFFECT OF PARATHYROID HORMONE (1-34) ON FRACTURES AND BONE MINERAL DENSITY IN POSTMENOPAUSAL WOMEN WITH OSTEOPOROSIS", NEJM, (20010000), vol. 344, no. 19, pages 1434 - 1441, XP009060029
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OPPOSITION- lane et al, "Parathyroid hormone treatment can reverse corticosteroid-induced osteoporosis. Results of a randomized controlled clinical trial", J. Clin. Invest., (19980000), vol. 102, no. 8, pages 1627 - 1633, XP055378485
OPPOSITION- cosman et al, "- ALENDRONATE DOES NOT BLOCK THE ANABOLIC EFFECT OF PTH IN POSTMENOPAUSAL OSTEOPOROTIC WOMEN", Journal of Bone and Mineral Research, (19980000), vol. 13, no. 6, pages 1051 - 1055, XP000982943
OPPOSITION- COSMAN F; ET AL, "ALENDRONATE DOES NOT BLOCK THE ANABOLIC EFFECT OF PTH IN POSTMENOPAUSAL OSTEOPOROTIC WOMEN", Journal of Bone and Mineral Research, (19980000), vol. 13, no. 6, pages 1051 - 1055, XP000982943
OTHER- R. LINDSAY et al., "Randomised controlled study of effect of parathyroid hormone on vertebral-bone mass and fracture incidence among postmenopausal women on oestrogen with osteoporosis", The Lancet, (19970823), vol. 350, pages 550 - 555, XP002127205
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SEARCH- MASAO FUKUNAGA ET AL., "Effect of small dose of human parathyroid hormone (1-34) on bone mass in the lumbar vertebrae in Patients with senile osteoporosis", JOURNAL OF CLINICAL THERAPEUTICS AND MEDICINE, Tokyo, (1997), vol. 13, no. 13, pages 3371 - 3382, XP002739050 [Y] 1-4 * the whole document * * table 2 *-
SEARCH- REEVE J ET AL, "Anabolic effect of human parathyroid hormone fragment on trabecular bone in involutional osteoporosis: a multicentre trial.", BRITISH MEDICAL JOURNAL 7 JUN 1980, (19800607), vol. 280, no. 6228, ISSN 0007-1447, pages 1340 - 1344, XP009082560 [Y] 1-4 * the whole document * * Table; page 1341 *-
SEARCH- R.M. NEER ET AL., "The use of parathyroid hormone plus 1,25-dihydroxyvitamin D to increase trabecular bone in osteoporotic men and postmenopausal women", OSTEOPOROSIS, (1987), vol. 2, pages 829 - 835, XP002549387 [Y] 1-4 * the whole document *-
SEARCH- SLOVIK ET AL, "JOIJWNAI. OF BONE A N D MINERAL RESEARCH Volume I . Number 4, 1986 Mary Restoration of Spinal Bone in Osteoporotic Men by Treatment With Human Parathyroid Hormone (1 -34) and 1,25-Dihydroxyvitamin D", JOURNAL OF BONE AND MINERAL RESEARCH, (1986), vol. 1, no. 4, pages 377 - 381, XP002739054 [X] 1,2,4 * the whole document * * page 377, column r, paragraph 2 * * page 378, column l, paragraphs 2, 3 * [Y] 1-4
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