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Botulinum Toxin Assay With Improved Sensitivity - EP3030905

The patent EP3030905 was granted to Biomadison on Apr 3, 2024. The application was originally filed on Aug 8, 2014 under application number EP14761444A. The patent is currently recorded with a legal status of "Patent Maintained As Amended".

EP3030905

BIOMADISON
Application Number
EP14761444A
Filing Date
Aug 8, 2014
Status
Patent Maintained As Amended
Dec 8, 2023
Publication Date
Apr 3, 2024
External Links
Slate, Register, Google Patents

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MERZ PHARMAJun 28, 2018ALTMANN STOSSEL DICK PATENTANWALTE PARTG MBB -

Patent Citations (19) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication Number
DESCRIPTIONUS2004191887
DESCRIPTIONUS2006134722
DESCRIPTIONUS2011033866
DESCRIPTIONUS7183066
DESCRIPTIONUS7208285
DESCRIPTIONWO2014060373
INTERNATIONAL-SEARCH-REPORTWO2009014854
INTERNATIONAL-SEARCH-REPORTWO2009035476
INTERNATIONAL-SEARCH-REPORTWO2013103737
OPPOSITIONUS2006134722
OPPOSITIONUS2008064054
OPPOSITIONUS2010209955
OPPOSITIONWO2007001358
OPPOSITIONWO2009035476
OPPOSITIONWO2009114748
OPPOSITIONWO2012166943
OPPOSITIONWO2013103737
OPPOSITIONWO2013131991
OPPOSITIONWO2014060373

Non-Patent Literature (NPL) Citations (11) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference Text
DESCRIPTION- FOSTER; STRINGER, GENETIC REGULATORY ELEMENTS INTRODUCED INTO NEURAL STEM AND PROGENITOR CELL POPULATIONS, BRAIN PATHOLOGY, (1999), vol. 9, pages 547 - 567
INTERNATIONAL-SEARCH-REPORT- F. M. DUNNING ET AL, "Detection of Botulinum Neurotoxin Serotype A, B, and F Proteolytic Activity in Complex Matrices with Picomolar to Femtomolar Sensitivity", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, (20120824), vol. 78, no. 21, doi:10.1128/AEM.01664-12, ISSN 0099-2240, pages 7687 - 7697, XP055151398 [A] 1-21 * page 7689, figure 1 and column 1, last paragraph *
INTERNATIONAL-SEARCH-REPORT- NUSS JONATHAN E ET AL, "Development of cell-based assays to measure botulinum neurotoxin serotype A activity using cleavage-sensitive antibodies", JOURNAL OF BIOMOLECULAR SCREENING, SAGE; LIEBERT, US, (20100101), vol. 15, no. 1, doi:10.1177/1087057109354779, ISSN 1087-0571, pages 42 - 51, XP008124093 [A] 1-21 * page 43, column 2 first line; page 44 first passage. *
OPPOSITION- BLACK et al., "Interaction of 125I-labeled botulinum neurotoxins with nerve terminals. II. Autoradiographic evidence for its uptake into motor nerves by acceptor-mediated endocytosis.", The Journal of Cell Biology, (19860000), vol. 103, pages 535 - 544, XP055514881
OPPOSITION- "Media formulation Neurobasal medium", Technical Resources , thermo fisher scientific, URL: https://www.thermofisher.com/us/en/home/technical-resources/media-formulation.251.html
OPPOSITION- PELLET, "Progress in cell based assays for botulinum neurotoxin detection", Curr. Top. Microbiol. Immunol., (20130000), vol. 364, pages 257 - 285, XP055111189
OPPOSITION- POULAIN et al., "Differences in the temperature dependencies of uptake of botulinum and tetanus toxins in Aplysia neurons.", Neuroscience Letters, (19920000), vol. 139, pages 289 - 292, XP024162799
OPPOSITION- RUGE et al., Anal. Biochem., (20110000), vol. 411, pages 200 - 209, XP028171767
OPPOSITION- PIRAZZINI et al., Biochemical and Biophysical Research Com- munications, (20130000), vol. 430, pages 38 - 42, XP028962880
OPPOSITION- PIER et al., FEBS Lett., (20110000), vol. 585, pages 199 - 206, XP055012305
OPPOSITION- DONG et al., "Using fluorescent sensors to detect botulinium neurotoxin activity in vitro and in living cells", PNAS, (20040000), vol. 101, pages 14701 - 14706, XP008156528

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