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Materials And Methods To Enhance Hematopoietic Stem Cells Engraftment Procedures - EP3031907

The patent EP3031907 was granted to Indiana University Research And Technology on Jan 6, 2021. The application was originally filed on Nov 6, 2009 under application number EP16153526A. The patent is currently recorded with a legal status of "Revoked".

EP3031907

INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY
Application Number
EP16153526A
Filing Date
Nov 6, 2009
Status
Revoked
Oct 13, 2023
Grant Date
Jan 6, 2021
External Links
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JAMES POOLEOct 6, 2021CARPMAELS & RANSFORD -

Patent Citations (7) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication Number
DESCRIPTIONWO2010054271
EXAMINATIONWO2007112084
EXAMINATIONWO9748815
OPPOSITIONWO2007112084
OPPOSITIONWO9748815
OTHERWO2007112084
OTHERWO9748815

Non-Patent Literature (NPL) Citations (42) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference Text
DESCRIPTION- BREYER,R.M.; BAGDASSARIAN,C.K.; MYERS,S.A.; BREYER,M.D., "Prostanoid receptors: subtypes and signaling", ANNU. REV. PHARMACOL. TOXICOL., (2001), vol. 41, pages 661 - 690
DESCRIPTION- CHENG,T.; RODRIGUES,N.; SHEN,H.; YANG,Y.; DOMBKOWSKI,D.; SYKES,M.; SCADDEN,D.T., "Hematopoietic stem cell quiescence maintained by p21cipl/wafl", SCIENCE, (2000), vol. 287, pages 1804 - 1808
DESCRIPTION- "Cord Blood Hematopoietic Stem and Progenitor Cells", BROXMEYER,H.E, Essentials of Stem Cell Biology, ELSEVIER, (2006), pages 133 - 137
DESCRIPTION- FLEMING,H.E.; JANZEN,V.; LO,C.C.; GUO,J.; LEAHY,K.M.; KRONENBERG,H.M.; SCADDEN,D.T, "Wnt signaling in the niche enforces hematopoietic stem cell quiescence and is necessary to preserve self-renewal in vivo", CELL STEM CELL, (2008), vol. 2, pages 274 - 283
DESCRIPTION- FRUEHAUF,S; SEGGEWISS,R., "It's moving day: factors affecting peripheral blood stem cell mobilization and strategies for improvement [corrected", BR. J. HAEMATOL, (2003), vol. 122, pages 360 - 375
DESCRIPTION- FUKUDA,S.; MANTEL,C.R.; PELUS,L.M, "Survivin regulates hematopoietic progenitor cell proliferation through p21WAFl/Cipl-dependent and -independent pathways", BLOOD, (2004), vol. 103, pages 120 - 127
DESCRIPTION- FUKUDA,S; PELUS,L.M, "Regulation of the inhibitor-of-apoptosis family member survivin in normal cord blood and bone marrow CD34(+) cells by hematopoietic growth factors: implication of survivin expression in normal hematopoiesis", BLOOD, (2001), vol. 98, pages 2091 - 2100
DESCRIPTION- GOLDMAN,J.M.; HOROWITZ,M.M., "The international bone marrow transplant registry", INT. J. HEMATOL., (2002), vol. 76, no. 1, pages 393 - 397
DESCRIPTION- HALL,K.M.; HORVATH,T.L.; ABONOUR,R.; CORNETTA,K.; SROUR,E.F., "Decreased homing ofretrovirally transduced human bone marrow CD34+ cells in the NOD/SCID mouse model", EXP. HEMATOL., (2006), vol. 34, pages 433 - 442
DESCRIPTION- JANZEN,V.; FLEMING,H.E.; RIEDT,T.; KARLSSON,G.; RIESE,M.J.; LO,C.C.; REYNOLDS,G.; MILNE,C.D.; PAIGE,C.J.; KARLSSON,S, "Hematopoietic stem cell responsiveness to exogenous signals is limited by caspase-3", CELL STEM CELL, (2008), vol. 2, pages 584 - 594
DESCRIPTION- KHAN,N.I.; BENDALL,L.J., "Role of WNT signaling in normal and malignant hematopoiesis", HISTOL. HISTOPATHOL., (2006), vol. 21, pages 761 - 774
DESCRIPTION- LI,F; AMBROSINI,G.; CHU,E.Y.; PLESCIA,J.; TOGNIN,S.; MARCHISIO,P.C.; ALTIERI,D.C., "Control of apoptosis and mitotic spindle checkpoint by survivin", NATURE, (1998), vol. 396, pages 580 - 584
DESCRIPTION- LIU,X.H.; KIRSCHENBAUM,A.; LU,M.; YAO,S.; DOSORETZ,A.; HOLLAND,J.F.; LEVINE,A.C., "Prostaglandin E2 induces hypoxia-inducible factor- alpha stabilization and nuclear localization in a human prostate cancer cell line", J BIOL CHEM, (2002), vol. 277, pages 50081 - 50086
DESCRIPTION- MULLER-SIEBURG,C.E.; SIEBURG,H.B, "Clonal diversity of the stem cell compartment", CURR OPIN HEMATOL, (2006), vol. 13, pages 243 - 248
DESCRIPTION- NAMBA,T.; SUGIMOTO,Y.; NEGISHI,M.; IRIE,A.; USHIKUBI,F.; KAKIZUKA,A.; ITO,S.; ICHIKAWA,A.; NARUMIYA,S., "Alternative splicing of C-terminal tail of prostaglandin E receptor subtype EP3 determines G-protein specificity", NATURE, (1993), vol. 365, pages 166 - 170
DESCRIPTION- NORTH,T.E.; GOESSLING,W.; WALKLEY,C.R.; LENGERKE,C.; KOPANI,K.R.; LORD,A.M.; WEBER,G.J.; BOWMAN,T.V.; JANG,I.H.; GROSSER,T., "Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasis", NATURE, (2007), vol. 447, pages 1007 - 1011
DESCRIPTION- OKADA,S.; NAKAUCHI,H.; NAGAYOSHI,K.; NISHIKAWA,S.; MIURA,Y.; SUDA,T., "In vivo and in vitro stem cell function of c-kit- and Sca- I -positive murine hematopoietic cells", BLOOD, (1992), vol. 80, pages 3044 - 3050
DESCRIPTION- PELUS, EXPERIMENTAL HEMATOLOGY, (2005), vol. 33, pages 295 - 307
DESCRIPTION- PENG,X.H.; KARNA,P.; CAO,Z.; JIANG,B.H.; ZHOU,M.; YANG,L., "Cross-talk between epidermal growth factor receptor and hypoxia-inducible factor- alpha signal pathways increases resistance to apoptosis by up-regulating survivin gene expression", J BIOL CHEM, (2006), vol. 281, pages 25903 - 25914
DESCRIPTION- PICCOLI,C.; D'APRILE,A.; RIPOLI,M.; SCRIMA,R.; BOFFOLI,D.; TABILIO,A.; CAPITANIO,N., "The hypoxia-inducible factor is stabilized in circulating hematopoietic stem cells under normoxic conditions", FEBS LETT, (2007), vol. 581, pages 3111 - 3119
DESCRIPTION- PORECHA,N.K.; ENGLISH,K.; HANGOC,G.; BROXMEYER,H.E.; CHRISTOPHERSON,K.W, "Enhanced functional response to CXCL12/SDF-1 through retroviral overexpression of CXCR4 on M07e cells: implications for hematopoietic stem cell transplantation.", STEM CELLS DEV., (2006), vol. 15, pages 325 - 333
DESCRIPTION- PULSIPHER MA; CHITPHAKDITHAI P; LOGAN BR; LEITMAN SF; ANDERLINI P; KLEIN JP; HOROWITZ MM; MILLER JP; KING RJ; CONFER DL, "Donor, recipient, and transplant characteristics as risk factors after unrelated donor PBSC transplantation: beneficial effects of higher CD34+ cell dose", BLOOD, (20090716), vol. 114, no. 13, pages 2606 - 2616
DESCRIPTION- REGAN,J.W., "EP2 and EP4 prostanoid receptor signaling", LIFE SCI., (2003), vol. 74, pages 143 - 153
DESCRIPTION- SPANGRUDE,G.J.; SCOLLAY,R., "A simplified method for enrichment of mouse hematopoietic stem cells", EXP. HEMATOL., (1990), vol. 18, pages 920 - 926
DESCRIPTION- STALLER,P.; SULITKOVA,J.; LISZTWAN,J., MOCH,H.; OAKELEY,E.J.; KREK,W., "Chemokine receptor CXCR4 downregulated by von Hippel-Lindau tumour suppressor pVHL", NATURE, (2003), vol. 425, pages 307 - 311
DESCRIPTION- SUGIMOTO,Y.; NARUMIYA,S., "Prostaglandin E receptors", J. BIOL. CHEM., (2007), vol. 282, pages 11613 - 11617
DESCRIPTION- TAMM,I.; WANG,Y.; SAUSVILLE,E.; SCUDIERO,D.A.; VIGNA,N.; OLTERSDORF,T.; REED,J.C., "IAP-family protein survivin inhibits caspase activity and apoptosis induced by Fas (CD95), Bax, caspases, and anticancer drugs", CANCER RES., (1998), vol. 58, pages 5315 - 5320
DESCRIPTION- TSUBOI,K.; SUGIMOTO,Y.; ICHIKAWA,A, "Prostanoid receptor subtypes", PROSTAGLANDINS OTHER LIPID MEDIAT., (2002), vol. 68-69, pages 535 - 556
DESCRIPTION- ZAGZAG,D.; KRISHNAMACHARY,B.; YEE,H.; OKUYAMA,H.; CHIRIBOGA,L.; ALI,M.A; MELAMED,J.; SEMENZA,G.L., "Stromal cell-derived factor-lalpha and CXCR4 expression in hemangioblastoma and clear cell-renal cell carcinoma: von Hippel-Lindau loss-of-function induces expression of a ligand and its receptor", CANCER RES, (2005), vol. 65, pages 6178 - 6188
EXAMINATION- KRISTIN M. HALL ET AL, "Decreased homing of retrovirally transduced human bone marrow CD34+ cells in the NOD/SCID mouse model", EXPERIMENTAL HEMATOLOGY, US, (20060401), vol. 34, no. 4, doi:10.1016/j.exphem.2005.12.014, ISSN 0301-472X, pages 433 - 442, XP055534780
OPPOSITION- ANDRADE-ZALDIVAR et al., "Expansion of human hematopoietic stem cells for transplantation: trends and perspectives", Cytotechnology, (20080329), vol. 56, no. 3, pages 151 - 160, XP019602514
OPPOSITION- Zubler Rudolf H., "Ex vivo expansion of haematopoietic stem cells and gene therapy development", Swiss Med. Wkly, (20060101), vol. 136, pages 795 - 799, XP055864367
OPPOSITION- Kristin M. Hall, Tamara L. Horvath, Rafat Abonour, Kenneth Cornetta, Edward F. Srour, "Decreased homing of retrovirally transduced human bone marrow CD34+ cells in the NOD/SCID mouse model", Experimental hematalogy, Elsevier Inc., US, US , (20060401), vol. 34, no. 4, doi:10.1016/j.exphem.2005.12.014, ISSN 0301-472X, pages 433 - 442, XP055534780
OPPOSITION- Horn, P.A. Morris, J.C. Neff, T. Kiem, H.-P., "Stem cell gene transfer-efficacy and safety in large animal studies", Molecular Therapy, Elsevier Inc., US, US , (20040901), vol. 10, no. 3, doi:10.1016/j.ymthe.2004.05.017, ISSN 1525-0016, pages 417 - 431, XP004536752
OPPOSITION- Trista E. North, Wolfram Goessling, Carl R. Walkley, Claudia Lengerke, Kamden R. Kopani, Allegra M. Lord, Gerhard J. Weber, Teresa V. Bowman, Il-Ho Jang, Tilo Grosser, Garret A. FitzGerald, George Q. Daley, Stuart H. Orkin, Leonard I. Zon, "Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasis", Nature, ¬Macmillan Journals Ltd., etc.|, (20070621), vol. 447, no. 7147, doi:10.1038/nature05883, ISSN 00280836, pages 1007 - 1011, XP055002054
OPPOSITION- Arthur Bank, "Hematopoietic stem cell gene therapy: selecting only the best", The Journal of Clinical Investigation, B M J Group, GB, GB , (20031115), vol. 112, no. 10, doi:10.1172/JCI20336, ISSN 0021-9738, pages 1478 - 1480, XP055270573
OPPOSITION- LAPIDOT T, DAR A, KOLLET O, "How do stem cells find their way home?", Blood, American Society of Hematology, US, US , (20050915), vol. 106, no. 6, doi:10.1182/blood-2005-04-1417, ISSN 0006-4971, pages 1901 - 1910, XP003011680
OPPOSITION- Allegra M. Lord, Trista E. North, Leonard I. Zon, "Prostaglandin E2: Making More of Your Marrow", Cell Cycle, Landes Bioscience, (20071215), vol. 6, no. 24, doi:10.4161/cc.6.24.5129, ISSN 15384101, pages 3054 - 3057, XP055058145
SEARCH- HORN P A ET AL, "Stem cell gene transfer-efficacy and safety in large animal studies", MOLECULAR THERAPY, NATURE PUBLISHING GROUP, GB, (20040901), vol. 10, no. 3, doi:10.1016/J.YMTHE.2004.05.017, ISSN 1525-0016, pages 417 - 431, XP004660583 [X] 10-13 * the whole document * * "Conclusions"; page 427 * [A] 1-9
SEARCH- TRISTA E. NORTH ET AL, "Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasis", NATURE, (20070621), vol. 447, no. 7147, doi:10.1038/nature05883, ISSN 0028-0836, pages 1007 - 1011, XP055002054 [X] 9 * the whole document * [A] 1-8,10-13
SEARCH- ARTHUR BANK, "Hematopoietic stem cell gene therapy: selecting only the best", JOURNAL OF CLINICAL INVESTIGATION, US, (20031115), vol. 112, no. 10, doi:10.1172/JCI20336, ISSN 0021-9738, pages 1478 - 1480, XP055270573 [X] 10-13 * the whole document * * page 1479; figure 1 * [A] 1-9
SEARCH- ALLEGRA M. LORD ET AL, "Prostaglandin E2: Making More of Your Marrow", CELL CYCLE, (20071215), vol. 6, no. 24, doi:10.4161/cc.6.24.5129, ISSN 1538-4101, pages 3054 - 3057, XP055058145 [X] 9 * the whole document * * page 3055, column R, paragraph 4 - page 3057, column L, paragraph 2 * [A] 1-8,10-13

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