| DESCRIPTION | - AL-LAZIKANI ET AL., J. MOLEC. BIOL., (1997), vol. 273, pages 927 - 948 | - |
| DESCRIPTION | - "A model of evolutionary change in proteins - Matrices for detecting distant relationships", DAYHOFF, M.O., Atlas of Protein Sequence and Structure, NATIONAL BIOMEDICAL RESEARCH FOUNDATION, (1978), vol. 5, pages 345 - 358 | - |
| DESCRIPTION | - ARULMANI ET AL., CEPHALALGIA, (2005), vol. 25, pages 1082 - 1090 | - |
| DESCRIPTION | - ARULMANI ET AL., EUR. J. PHARMACOL., (2004), vol. 500, pages 315 - 330 | - |
| DESCRIPTION | - BALINT ET AL., GENE, (1993), vol. 137, no. L, pages 109 - 18 | - |
| DESCRIPTION | - BARBAS ET AL., PROC NAT. ACAD. SCI, USA, (1994), vol. 91, pages 3809 - 3813 | - |
| DESCRIPTION | - BARBAS, Phage display: a laboratory manual, COLD SPRING HARBOR LABORATORY PRESS, (2001), page 2.10 | - |
| DESCRIPTION | - BERENDSEN ET AL., EUROPEAN JOURNAL OF PHARMACOLOGY, (2001), vol. 419, no. 1, pages 47 - 54 | - |
| DESCRIPTION | - BIRD ET AL., SCIENCE, (1988), vol. 242, pages 423 - 426 | - |
| DESCRIPTION | - BOERNER ET AL., J. IMMUNOL., (1991), vol. 147, no. 1, pages 86 - 95 | - |
| DESCRIPTION | - BOYD ET AL., MOL. LMMUNOL., (1996), vol. 32, pages 1311 - 1318 | - |
| DESCRIPTION | - BRAIN, S. ET AL., TRENDS IN PHARMACOLOGICAL SCIENCES, (2002), vol. 23, pages 51 - 53 | - |
| DESCRIPTION | - BROWN ET AL., CANCER RES., (1987), vol. 47, pages 3577 - 3583 | - |
| DESCRIPTION | - BUCK, D. W. ET AL., IN VITRO, (1982), vol. 18, pages 377 - 381 | - |
| DESCRIPTION | - CAPEL ET AL., IMMUNOMETHODS, (1994), vol. 4, pages 25 - 34 | - |
| DESCRIPTION | - CLACKSON ET AL., NATURE, (1991), vol. 352, pages 624 - 628 | - |
| DESCRIPTION | - CLYNES ET AL., PNAS (USA, (1998), vol. 95, pages 652 - 656 | - |
| DESCRIPTION | - COLE ET AL., Monoclonal Antibodies and Cancer Therapy, ALAN R. LISS, (1985), page 77 | - |
| DESCRIPTION | - CONNELLY, HUMAN GENE THERAPY, (1995), vol. 1, page 185 | - |
| DESCRIPTION | - CURIEL, HUM. GENE THER., (1992), vol. 3, page 147 | - |
| DESCRIPTION | - DAUGHERTY ET AL., NUCL. ACIDS RES., (1991), vol. 19, pages 2471 - 2476 | - |
| DESCRIPTION | - DURHAM, N. ENGL. J. MED., (2004), vol. 350, pages 1073 - 1075 | - |
| DESCRIPTION | - EPSTEIN ET AL., PROC. NATL. ACAD. SCI. USA, (1985), vol. 82, page 3688 | - |
| DESCRIPTION | - ESCOTT ET AL., BR. J. PHARMACOL., (1993), vol. 110, pages 772 - 776 | - |
| DESCRIPTION | - EUR. J. IMMUNOL, (1999), vol. 29, pages 2613 - 2624 | - |
| DESCRIPTION | - EUR. J. IMMUNOL., (1999), vol. 29, pages 2613 - 2624 | - |
| DESCRIPTION | - EUR. J. LMMUNOL., (1999), vol. 29, pages 2613 - 2624 | - |
| DESCRIPTION | - FINDEIS ET AL., TRENDS BIOTECHNOL., (1993), vol. 11, page 202 | - |
| DESCRIPTION | - FREEDMAN, AM. J. HUMAN BIOL., (2001), vol. 13, pages 453 - 464 | - |
| DESCRIPTION | - GAZZANO-SANTORO ET AL., J. IMMUNOL. METHODS, (1996), vol. 202, page 163 | - |
| DESCRIPTION | - GEERLIGS HJ ET AL., J. IMMUNOL. METHODS, (1989), vol. 124, pages 95 - 102 | - |
| DESCRIPTION | - GIFFIN ET AL., CEPHALALGIA, (2003), vol. 23, pages 287 - 292 | - |
| DESCRIPTION | - GOADSBY ET AL., ANN. NEUROL., (1990), vol. 28, pages 183 - 7 | - |
| DESCRIPTION | - GOADSBY ET AL., BRAIN, (2002), vol. 125, pages 1392 - 401 | - |
| DESCRIPTION | - GOADSBY ET AL., N. ENGL. J. MED., (2002), vol. 346, pages 257 - 270 | - |
| DESCRIPTION | - GOADSBY ET AL., NEW ENGL. J. MED., (2002), vol. 346, no. 4, pages 257 - 275 | - |
| DESCRIPTION | - GOADSBY, P.J. ET AL., NEW ENGL. J. MED., (2002), vol. 346, no. 4, pages 257 - 275 | - |
| DESCRIPTION | - GRIFFITH ET AL., EMBO J., (1993), vol. 12, pages 725 - 734 | - |
| DESCRIPTION | - GUYER ET AL., J. IMMUNOL., (1976), vol. 117, page 587 | - |
| DESCRIPTION | - HAAS ET AL., J. LAB. CLIN. MED., (1995), vol. 126, pages 330 - 41 | - |
| DESCRIPTION | - Handbook of Experimental Immunology | - |
| DESCRIPTION | - HAWKINS ET AL., J. MOL. BIOL., (1992), vol. 226, pages 889 - 896 | - |
| DESCRIPTION | - HIGGINS, D.G.; SHARP, P.M., CABIOS, (1989), vol. 5, pages 151 - 153 | - |
| DESCRIPTION | - HOLLIGER, P. ET AL., PROC. NATL. ACAD SCI. USA, (1993), vol. 90, pages 6444 - 6448 | - |
| DESCRIPTION | - HOOGENBOOM; WINTER, J. MOL. BIOL., (1991), vol. 227, page 381 | - |
| DESCRIPTION | - HSE ET AL., J. BIOL. CHEM., (1997), vol. 272, pages 9062 - 9070 | - |
| DESCRIPTION | - HWANG ET AL., PROC. NATL ACAD. SCI. USA, (1980), vol. 77, page 4030 | - |
| DESCRIPTION | - JACKSON ET AL., J. IMMUNOL., (1995), vol. 154, no. 7, pages 3310 - 9 | - |
| DESCRIPTION | - JEFFERIS ET AL., IMMUNOLOGICAL REVIEWS, (1998), vol. 163, pages 59 - 76 | - |
| DESCRIPTION | - JEFFERIS; LUND, CHEM. IMMUNOL., (1997), vol. 65, pages 111 - 128 | - |
| DESCRIPTION | - JOHNSON, KEVIN S.; CHISWELL, DAVID J., CURRENT OPINION IN STRUCTURAL BIOLOGY, (1993), vol. 3, pages 564 - 571 | - |
| DESCRIPTION | - JOLLY, CANCER GENE THERAPY, (1994), vol. 1, page 51 | - |
| DESCRIPTION | - JONES ET AL., NATURE, (1986), vol. 321, pages 522 - 525 | - |
| DESCRIPTION | - KAPLITT, NATURE GENETICS, (1994), vol. 6, page 148 | - |
| DESCRIPTION | - KARLSSON, R.; ROOS, H.; FAGERSTAM, L.; PETERSSON, B., METHODS ENZYMOLOGY, (1994), vol. 6, pages 99 - 110 | - |
| DESCRIPTION | - KATOVICH ET AL., BRAIN RES., (1989), vol. 494, pages 85 - 94 | - |
| DESCRIPTION | - KATOVICH ET AL., PROCEEDINGS OF THE SOCIETY FOR EXPERIMENTAL BIOLOGY & MEDICINE, (1990), vol. 193, no. 2, pages 129 - 35 | - |
| DESCRIPTION | - KENNEY JS ET AL., J. IMMUNOL. METHODS, (1989), vol. 121, pages 157 - 166 | - |
| DESCRIPTION | - KIM ET AL., J. IMMUNOL., (1994), vol. 24, page 249 | - |
| DESCRIPTION | - KIMURA, HUMAN GENE THERAPY, (1994), vol. 5, page 845 | - |
| DESCRIPTION | - KOHLER, B.; MILSTEIN, C., NATURE, (1975), vol. 256, pages 495 - 497 | - |
| DESCRIPTION | - KOHLER; MILSTEIN, NATURE, (1975), vol. 256, page 495 | - |
| DESCRIPTION | - KRAMER; MURPHY ET AL., Int'I Symposium on Recent Advances in Urological Cancer Diagnosis and Treatment-Proceedings, PARIS, FRANCE: SCI, (1992), pages 3 - 7 | - |
| DESCRIPTION | - LASSEN ET AL., CEPHALALGIA, (2002), vol. 22, pages 54 - 61 | - |
| DESCRIPTION | - LDUSOGIE ET AL., J. IMMUNOLOGY, (2000), vol. 164, pages 4178 - 4184 | - |
| DESCRIPTION | - LOBUGLIO ET AL., PROC. NAT. ACAD. SCI. USA, (1989), vol. 86, pages 4220 - 4224 | - |
| DESCRIPTION | - LONBERG, N.; D. HUSZAR, LNT.REV.LMMUNOL, (1995), vol. 13, page 65 | - |
| DESCRIPTION | - LUND ET AL., J. IMMUNOLOGY, (1996), vol. 157, pages 4963 - 9 | - |
| DESCRIPTION | - MALLEE ET AL., J. BIOL. CHEM., (2002), vol. 277, pages 14294 - 8 | - |
| DESCRIPTION | - MARK ET AL., J. MOL. BIOL., (1991), vol. 222, pages 581 - 597 | - |
| DESCRIPTION | - MARKS ET AL., BIO/TECHNOL., (1992), vol. 10, pages 779 - 783 | - |
| DESCRIPTION | - MARKS ET AL., BIO/TECHNOLOGY, (1992), vol. 10, pages 779 - 783 | - |
| DESCRIPTION | - MARKS ET AL., J. MOL. BIOL., (1991), vol. 222, page 581 | - |
| DESCRIPTION | - MCCAFFERTY ET AL., NATURE, (1990), vol. 348, pages 552 - 553 | - |
| DESCRIPTION | - MCCAFFERTY ET AL., NATURE, (1990), vol. 348, pages 552 - 554 | - |
| DESCRIPTION | - MERCHENTHALER ET AL., MATURITAS, (1998), vol. 30, pages 307 - 316 | - |
| DESCRIPTION | - Methods in Enzymology, ACADEMIC PRESS, INC. | - |
| DESCRIPTION | - Methods in Molecular Biology, HUMANA PRESS | - |
| DESCRIPTION | - MILLSTEIN; CUELLO, NATURE, (1983), vol. 305, pages 537 - 539 | - |
| DESCRIPTION | - MORGAN ET AL., IMMUNOLOGY, (1995), vol. 86, pages 319 - 324 | - |
| DESCRIPTION | - MORRISON ET AL., PROC. NAT. ACAD. SCI., (1984), vol. 81, page 6851 | - |
| DESCRIPTION | - MYERS, E.W.; MULLER W., CABIOS, (1988), vol. 4, pages 11 - 17 | - |
| DESCRIPTION | - PEETERS ET AL., VACCINE, (2001), vol. 19, page 2756 | - |
| DESCRIPTION | - PHILIP, MOL. CELL BIOL., (1994), vol. 14, page 2411 | - |
| DESCRIPTION | - PLOURDE ET AL., PEPTIDES, (1993), vol. 14, pages 1225 - 1229 | - |
| DESCRIPTION | - POLJAK, R. J. ET AL., STRUCTURE, (1994), vol. 2, pages 1121 - 1123 | - |
| DESCRIPTION | - POLLOCK ET AL., J IMMUNOL METHODS, (1999), vol. 231, page 147 | - |
| DESCRIPTION | - RAVETCH; KINET, ANN. REV. IMMUNOL., (1991), vol. 9, pages 457 - 92 | - |
| DESCRIPTION | - REUTER ET AL., FUNCTIONAL NEUROLOGY, (2000), vol. 3, no. 15 | - |
| DESCRIPTION | - RIECHMANN ET AL., NATURE, (1988), vol. 332, pages 323 - 327 | - |
| DESCRIPTION | - ROBINSON, E.D., COMB. THEOR., (1971), vol. 11, page 105 | - |
| DESCRIPTION | - SANTOU, N.; NES, M., MOL. BIOL. EVOL., (1987), vol. 4, pages 406 - 425 | - |
| DESCRIPTION | - SCHIER ET AL., GENE, (1995), vol. 169, pages 147 - 155 | - |
| DESCRIPTION | - SHAW ET AL., J LMMUNOL., (1987), vol. 138, pages 4534 - 4538 | - |
| DESCRIPTION | - SHEETS ET AL., PNAS, (USA, (1998), vol. 95, pages 6157 - 6162 | - |
| DESCRIPTION | - SIMPKINS ET AL., LIFE SCIENCES, (1983), vol. 32, pages 1957 - 1966 | - |
| DESCRIPTION | - SIPE ET AL., BRAIN RES., (2004), vol. 1028, no. 2, pages 191 - 202 | - |
| DESCRIPTION | - SURESH ET AL., METHODS IN ENZYMOLOGY, (1986), vol. 121, page 210 | - |
| DESCRIPTION | - TAN ET AL., CLIN. SCI., (1995), vol. 89, pages 656 - 73 | - |
| DESCRIPTION | - TAN ET AL., CLIN. SCI. (LOND)., (1995), vol. 89, pages 565 - 73 | - |
| DESCRIPTION | - TAO ET AL., J. IMMUNOLOGY, (1989), vol. 143, pages 2595 - 2601 | - |
| DESCRIPTION | - UMANA ET AL., MATURE BIOTECH., (1999), vol. 17, pages 176 - 180 | - |
| DESCRIPTION | - "Unified Approach to Alignment and Phylogenes", HEIN J., Methods in Enzymology, ACADEMIC PRESS, INC., (1990), vol. 183, pages 626 - 645 | - |
| DESCRIPTION | - VAUGHAN ET AL., NATURE BIOTECHNOLOGY, (1996), vol. 14, pages 309 - 314 | - |
| DESCRIPTION | - VERHOEYEN ET AL., SCIENCE, (1988), vol. 239, pages 1534 - 1536 | - |
| DESCRIPTION | - WATERHOUSE ET AL., NUCL. ACIDS RES., (1993), vol. 21, pages 2265 - 2266 | - |
| DESCRIPTION | - WICHER K ET AL., INT. ARCH. ALLERGY APPL. IMMUNOL., (1989), vol. 89, pages 128 - 135 | - |
| DESCRIPTION | - WILBUR, W.J.; LIPMAN, D.J., PROC. NATL. ACAD. SCI. USA, (1983), vol. 80, pages 726 - 730 | - |
| DESCRIPTION | - WILLIAMSON ET AL., CEPHALALGIA, (1997), vol. 17, no. 4, pages 518 - 24 | - |
| DESCRIPTION | - WINTER ET AL., ANNU. REV. IMMUNOL., (1994), vol. 12, pages 433 - 455 | - |
| DESCRIPTION | - WINTER ET AL., NATURE, (1991), vol. 349, pages 293 - 299 | - |
| DESCRIPTION | - WITTWE; HOWARD, BIOCHEM., (1990), vol. 29, pages 4175 - 4180 | - |
| DESCRIPTION | - WOFFENDIN, PROC. NATL. ACAD. SCI., (1994), vol. 91, page 1581 | - |
| DESCRIPTION | - WRIGHT; MORRISON, TIBTECH, (1997), vol. 15, pages 26 - 32 | - |
| DESCRIPTION | - WU ET AL., J. BIOL. CHEM., (1988), vol. 263, page 621 | - |
| DESCRIPTION | - WU ET AL., J. BIOL. CHEM., (1991), vol. 266, page 338 | - |
| DESCRIPTION | - WU, J. BIOL. CHEM., (1989), vol. 264, page 16985 | - |
| DESCRIPTION | - WU, J. BIOL. CHEM., (1994), vol. 269, page 542 | - |
| DESCRIPTION | - WYON ET AL., MENOPAUSE, (2000), vol. 7, no. 1, pages 25 - 30 | - |
| DESCRIPTION | - WYON ET AL., SCAND. J. UROL. NEPHROL., (2001), vol. 35, pages 92 - 96 | - |
| DESCRIPTION | - WYSS; WAGNER, CURRENT OPIN. BIOTECH., (1996), vol. 7, pages 409 - 416 | - |
| DESCRIPTION | - YELTON ET AL., J. IMMUNOL., (1995), vol. 155, pages 1994 - 2004 | - |
| DESCRIPTION | - ZENKE ET AL., PROC. NATL. ACAD. SCI. USA, (1990), vol. 87, page 3655 | - |
| DESCRIPTION | - ZIMMERMANN ET AL., PEPTIDES, (1995), vol. 16, pages 421 - 4 | - |
| EXAMINATION | - Max Reinshagen ET AL, "Calcitonin Gene-Related Peptide Mediates the Protective Effect of Sensory Nerves in a Model of Colonic Injury 1", (19980101), URL: http://jpet.aspetjournals.org/content/jpet/286/2/657.full.pdf, (20170418), XP055365033 | - |
| EXAMINATION | - WONG H C ET AL, "MONOCLONAL ANTIBODY TO RAT ALPHA-CGRP: PRODUCTION, CHARACTERIZATION, AND IN VIVO IMMUNONEUTRALIZATION ACTIVITY", HYBRI, LIEBERT, NEW YORK, NY, US, (19930101), vol. 12, no. 1, ISSN 0272-457X, pages 93 - 106, XP009082532 | - |
| EXAMINATION | - PESKAR B M ET AL, "A monoclonal antibody to calcitonin gene-related peptide abolishes capsaicin-induced gastroprotection", EUROPEAN JOURNAL OF PHARMACOLOGY, ELSEVIER SCIENCE, NL, vol. 250, no. 1, doi:10.1016/0014-2999(93)90645-X, ISSN 0014-2999, (19931130), pages 201 - 203, (19931130), XP025569068 | |
| EXAMINATION | - LOUIS S M ET AL, "The role of substance P and calcitonin gene-related peptide in neurogenic plasma extravasation and vasodilatation in the rat", NEUROSCIENCE, NEW YORK, NY, US, vol. 32, no. 3, doi:10.1016/0306-4522(89)90281-9, ISSN 0306-4522, (19890101), pages 581 - 586, (19890101), XP024383568 | |
| EXAMINATION | - BUCKLEY T L ET AL, "THE PARTIAL INHINITION OF INFLAMMATORY RESPONSES INDUCED BY CAPSAICIN USING THE FAB FRAGMENT OF A SELECTIVE CALCITONIN GENE-RELATED PEPTIDE ANTISERUM IN RABBIT SKIN", NEUROSCIENCE, NEW YORK, NY, US, (19920101), vol. 48, no. 4, doi:10.1016/0306-4522(92)90284-9, ISSN 0306-4522, pages 963 - 968, XP000563679 | |
| EXAMINATION | - DURHAM PAUL L, "CGRP-RECEPTOR ANTAGONISTS--A FRESH APPROACH TO MIGRAINE THERAPY?", NEW ENGLAND JOURNAL OF MEDICINE, THE -, MASSACHUSETTS MEDICAL SOCIETY, US, (20040311), vol. 350, no. 11, doi:10.1056/NEJMP048016, ISSN 1533-4406, pages 1073 - 1075, XP009082423 | |
| EXAMINATION | - VATER AXEL ET AL, "Short bioactive Spiegelmers to migraine-associated calcitonin gene-related peptide rapidly identified by a novel approach: tailored-SELEX", NUCLEIC ACIDS RESEARCH, OXFORD UNIVERSITY PRESS, GB, (20031101), vol. 31, no. 21, doi:10.1093/NAR/GNG130, ISSN 1362-4962, pages e130 - 1, XP002524779 | |
| OPPOSITION | - DOCKRAY G J et al., "lmmunoneutralization Studies with Calcitonin Gene-Related Peptide", Annals of NY Acad of Sci, (19920600), vol. 657, pages 258 - 267, XP055542288 | - |
| OPPOSITION | - DOODS H et al., "Pharmacological profile of BIBN4096BS, the first selective small molecule CGRP antagonist", British J of Pharmacol., (20000200), vol. 129, no. 3, pages 420 - 423, XP002613418 | - |
| OPPOSITION | - Edvinsson et al., "CGRP Involvement in Migraines", Edvinsson et al., Oleson et al., The Headaches Third Edition, Lippincott Williams & Wilkins, vol. 31, pages 289 - 299, ISBN 978-0-7817-5400-2, XP055542266 | - |
| OPPOSITION | - Extracts of International Classification of Headache 2004 Disorders | - |
| OPPOSITION | - "International Nonproprietary Names for Pharmaceutical Substances (INN)", Extract from WHO Drug Information, (20160000), vol. 30, no. 2, pages 241 - 242,280-281 | - |
| OPPOSITION | - MESSLINGER et al., "Abstracts of the XII Congress", International Headache Society 2005, (20051009), page 923 | - |
| OPPOSITION | - REINSHAGEN et al., "Calcitonin Gene-Related Peptide Mediates the Protective Effect of Sensory Nerves in a Model of Colonic Injury", J Pharmacol Exp Ther., (19980800), vol. 286, no. 2, pages 657 - 661, XP055365033 | - |
| OPPOSITION | - "Transcript of Teva Q3 Earning Call of", teva pharmaceutical industries, (20171102), URL: https://seekingalpha.com/article/4119613-teva- pharmaceutical-industries-teva-q3-2017-results-earnings-call- transcript? part=si ngle#question-answer -session, XP055536885 | - |
| OPPOSITION | - WONG H C et al., "Monoclonal antibody to rat alpha-CGRP: Production, characterization, and in vivo immunoneutralization activity", Hybridoma, (19930200), vol. 12, no. 1, pages 93 - 106, XP009082532 | - |
| OPPOSITION | - AN, ZHIQIANG, "Chapter 31 Therapeutic Antibodies in Clinical Use and Leading Clinical Candidates", AN, ZHIQIANG, Zhiqiang An, Therapeutic Monoclonal Antibodies From Bench to Clinic, John Wiley & Sons, (20090000), pages 711 - 762, XP055542663 | |
| OPPOSITION | - PESKAR B M et al., "A monoclonal antibody to calcitonin gene-related peptide abolishes capsaicin-induced gastroprotection", European Journal Pharmacology, (19931130), vol. 250, pages 201 - 203, XP025569068 | |
| OPPOSITION | - ROVERO P et al., "CGRP antagonist activity of short C-terminal fragments of human alphaCGRP, CGRP(23-37) and CGRP(19-37)", Peptides, (19920000), vol. 13, no. 5, pages 1025 - 1027, XP023982032 | |
| OPPOSITION | - LOUIS S M et al., "Antibodies to calcitonin-gene related peptide reduce inflammation induced by topical mustard oil but not that due to carrageenin in the rat", Neuroscience Letters, (19890731), vol. 102, no. 2-3, pages 257 - 260, XP024344553 | |
| OPPOSITION | - LOUIS S M et al., "The role of substance P and calcitonin gene-related peptide in neurogenic plasma extravasation and vasodilatation in the rat", Neuroscience, (19890000), vol. 32, no. 3, pages 581 - 586, XP024383568 | |
| OPPOSITION | - BUCKLEY T L et al., "The partial inhibition of inflammatory responses induced by capsaicin using the fab fragment of a selective calcitonin gene-related peptide antiserum in rabbit skin", Neuroscience, (19920600), vol. 48, no. 4, pages 963 - 968, XP024385805 | |
| OPPOSITION | - ARULMANI U et al., "Calcitonin gene-related peptide and its role in migraine pathophysiology", Eur J of Pharmacol, (20040814), vol. 500, pages 315 - 330, XP055542073 | |
| OPPOSITION | - HERSHEY et al., "Investigation of the species selectivity of a nonpeptide CGRP receptor antagonist using a novel pharmacodynamic assay", Regulatory Peptides, (20050000), vol. 127, pages 71 - 77, XP004744983 | |
| OPPOSITION | - LITTLE M et al., "Of mice and men: hybridoma and recombinant antibodies", Immunology Today, (20000802), vol. 8, no. 21, pages 364 - 370, XP004215163 | |
| OPPOSITION | - ZELLER J et al., "CGRP function-blocking antibodies inhibit neurogenic vasodilatation without affecting heart rate or arterial blood pressure in the rat", British Journal of Pharmacology, (20080908), vol. 155, no. 7, pages 1093 - 1103, XP002536469 | |
| OPPOSITION | - REICHERT et al., "Monoclonal antibody successes in the clinic", Nat Biotechnol., (20050900), vol. 23, no. 9, pages 1073 - 1078, XP002555770 | |
| OPPOSITION | - CARTER P J, "Potent antibody therapeutics by design", Nature Reviews Immunology, (20060500), vol. 6, no. 5, pages 343 - 357, XP007901440 | |
| OPPOSITION | - PETERSEN K A, "Inhibitory effect of BIBN4096BS on cephalic vasodilatation induced by CGRP or transcranial electrical stimulation in the rat", Br J Pharmacol., (20041100), vol. 143, no. 6, pages 697 - 704, XP055355211 | |
| OPPOSITION | - DENEKAS T et al., "Inhibition of stimulated meningeal blood flow by a calcitonin gene-related peptide binding mirror-image RNA oligonucleotide", British Journal of Pharmacology, (20060600), vol. 148, no. 4, pages 536 - 543, XP055057955 | |
| OPPOSITION | - TAN K K C et al., "Calcitonin generelated peptide as an endogenous vasodilator: immunoblockade studies in vivo with an anti-calcitonin generelated peptide monoclonal anti bodyand its Fab‘ fragment", Clinical Science, (19951200), vol. 89, no. 6, pages 565 - 573, XP009082539 | |
| OPPOSITION | - EDVINSSON L et al., "Neuropeptides in migraine luster headache", Cephalalgia, (19940000), vol. 14, pages 320 - 327, XP055542226 | |
| OPPOSITION | - LASSEN L H et al., "CGRP may play a causative role in migraine", Cephalalgia, (20020200), vol. 22, pages 54 - 61, XP009083987 | |
| OPPOSITION | - OLESEN J et al., "Calcitonin gene-related peptide receptor antagonist BIBN 4096 BS for the acute treatment of migraine", NEJM, (20040311), vol. 350, no. 11, pages 1104 - 1110, XP009181314 | |
| OPPOSITION | - DURHAM, "CGRP-Receptor Antagonists — A Fresh Approach to Migraine Therapy?", NEJM, (20040300), vol. 350, no. 11, pages 1073 - 1075, XP009082423 | |
| OPPOSITION | - GOADSBY P J et al., "Migraine - Current Understanding and Treatment", NEJM, (20020100), vol. 346, pages 257 - 270, XP055542054 | |
| OPPOSITION | - GOADSBY PJ et al., "Human in vivo evidence for trigeminovascular activation in cluster headache Neuropeptide changes and effects of acute attacks therapies", Brain, (19940600), vol. 117, page 427, XP055542113 | |
| OPPOSITION | - GOADSBY PJ., "New targets in the acute treatment of headache", Curr Opin Neurol, (20050600), vol. 18, no. 3, pages 283 - 288, XP055536888 | |
| OPPOSITION | - P.J. GOADSBY, "New targets in the acute treatment of headache", Current opinion in neurology, (20050000), vol. 18, no. 3, pages 283 - 288, XP055536888 | |
| OPPOSITION | - TAN K K C et al., "Demonstration of the neurotransmitter role of calcitonin gene-related peptides (CGRP) by immunoblockade with anti-CGRP monoclonal antibodies", Br. J. Pharmacol., (19940000), vol. 111, pages 703 - 710, XP055542346 | |
| OPPOSITION | - L. EDVINSSON, "New therapeutic target in primary headaches- blocking the CGRP receptor", Expert opinion on therapeutic tar- gets, (20030000), vol. 7, no. 3, pages 377 - 383, XP055536886 | |
| OPPOSITION | - CORREIA I R, "Stability of IgG isotypes in serum", mAbs, (20100500), vol. 2, no. 3, pages 221 - 232, XP055125978 | |
| SEARCH | - ROVERO P ET AL, "CGRP antagonist activity of short C-terminal fragments of human alphaCGRP, CGRP(23-37) and CGRP(19-37)", PEPTIDES, ELSEVIER, AMSTERDAM, NL, vol. 13, no. 5, doi:10.1016/0196-9781(92)90067-D, ISSN 0196-9781, (19920901), pages 1025 - 1027, (19920901), XP023982032 [Y] 1-15 * the whole document * | |
| SEARCH | - LITTLE M ET AL, "Of mice and men: hybridoma and recombinant antibodies", IMMUNOLOGY TODAY, ELSEVIER PUBLICATIONS, CAMBRIDGE, GB, (20000801), vol. 21, no. 8, doi:10.1016/S0167-5699(00)01668-6, ISSN 0167-5699, pages 364 - 370, XP004215163 [Y] 1-15 * page 366 * | |
| SEARCH | - ZELLER J ET AL, "CGRP function-blocking antibodies inhibit neurogenic vasodilatation without affecting heart rate or arterial blood pressure in the rat", BRITISH JOURNAL OF PHARMACOLOGY, NATURE PUBLISHING GROUP, BASINGSTOKE, HANTS; GB, (20081201), vol. 155, no. 7, doi:10.1038/BJP.2008.334, ISSN 0007-1188, pages 1093 - 1103, XP002536469 [T] * abstract; discussion * | |
| SEARCH | - TAN K K ET AL, "Calcitonin gene-related peptide as an endogenous vasodilator: immunoblockade studies in vivo with an anti-calcitonin gene-related peptide monoclonal antibody and its Fab' fragment.", CLINICAL SCIENCE (LONDON, ENGLAND : 1979) DEC 1995, (199512), vol. 89, no. 6, ISSN 0143-5221, pages 565 - 573, XP009082539 [Y] 1-15 * the whole document * | |
