Antibody Therapies For Human Immunodeficiency Virus (Hiv) - EP3052132

The patent EP3052132 was granted to Beth Israel Deaconess Medical Center on Jul 29, 2020. The application was originally filed on Sep 30, 2014 under application number EP14847004A. The patent is currently recorded with a legal status of "Granted And Under Opposition".

EP3052132

BETH ISRAEL DEACONESS MEDICAL CENTER
Application Number
EP14847004A
Filing Date
Sep 30, 2014
Status
Granted And Under Opposition
Jun 26, 2020
Grant Date
Jul 29, 2020
External Links
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JAMES POOLEApr 29, 2021CARPMAELS & RANSFORDADMISSIBLE

Patent Citations (21) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

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DESCRIPTIONUS2012288502
DESCRIPTIONUS2013251726
DESCRIPTIONUS5500362
DESCRIPTIONUS5821337
DESCRIPTIONUS6737056
DESCRIPTIONWO0138332
DESCRIPTIONWO2012030904
DESCRIPTIONWO2013055908
DESCRIPTIONWO2016014484
INTERNATIONAL-SEARCH-REPORTUS2005130125
INTERNATIONAL-SEARCH-REPORTUS2011295365
INTERNATIONAL-SEARCH-REPORTUS2013071406
INTERNATIONAL-SEARCH-REPORTUS2013251726
OPPOSITIONUS2005130125
OPPOSITIONUS2011295365
OPPOSITIONUS2013071406
OPPOSITIONUS2013251726
OPPOSITIONWO2012030904
OPPOSITIONWO2016014484
SEARCHWO2012030904
SEARCHWO2016014484

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OPPOSITION- Liang Shan, Robert F. Siliciano, "From reactivation of latent HIV-1 to elimination of the latent reservoir: The presence of multiple barriers to viral eradication", BIOESSAYS, John Wiley & Sons Ltd., GB, GB , (20130601), vol. 35, no. 6, doi:10.1002/bies.201200170, ISSN 0265-9247, pages 544 - 552, XP055285817
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OPPOSITION- J. A. Horwitz, A. Halper-Stromberg, H. Mouquet, A. D. Gitlin, A. Tretiakova, T. R. Eisenreich, M. Malbec, S. Gravemann, E. Billerbeck, M. Dorner, H. Buning, O. Schwartz, E. Knops, R. Kaiser, M. S. Seaman, J. M. Wilson, C. M. Rice, A. Ploss, P. J. Bjorkman, F. Klein, M. C. Nussenzweig, "HIV-1 suppression and durable control by combining single broadly neutralizing antibodies and antiretroviral drugs in humanized mice", Proceedings of the National Academy of Sciences, National Academy of Sciences, (20131008), vol. 110, no. 41, doi:10.1073/pnas.1315295110, ISSN 0027-8424, pages 16538 - 16543, XP055634703
OPPOSITION- V. Le Douce, A. Janossy, H. Hallay, S. Ali, R. Riclet, O. Rohr, C. Schwartz, "Achieving a cure for HIV infection: do we have reasons to be optimistic?", Journal of antimicrobial chemotherapy, OXFORD UNIVERSITY PRESS, GB, GB , (20120501), vol. 67, no. 5, doi:10.1093/jac/dkr599, ISSN 0305-7453, pages 1063 - 1074, XP055438880
OPPOSITION- L. Shan, Xing S., Yang H.-C., Zhang H., Margolick J. B., Siliciano R. F., "Unique characteristics of histone deacetylase inhibitors in reactivation of latent HIV-1 in Bcl-2-transduced primary resting CD4+ T cells", Journal of antimicrobial chemotherapy, OXFORD UNIVERSITY PRESS, GB, GB , (20140101), vol. 69, no. 1, doi:10.1093/jac/dkt338, ISSN 0305-7453, pages 28 - 33, XP055240694
OPPOSITION- Stuart A. Sievers, Louise Scharf, Anthony P. West, Pamela J. Bjorkman, "Antibody engineering for increased potency, breadth and half-life", Current Opinion in HIV and AIDS, Lippincott Williams & Wilkins, US, US , (20150501), vol. 10, no. 3, doi:10.1097/COH.0000000000000148, ISSN 1746-630X, pages 151 - 159, XP055328829
OPPOSITION- Lucio Gama, Celina M. Abreu, Erin N. Shirk, Sarah L. Price, Ming Li, Greg M. Laird, Kelly A. Metcalf Pate, Stephen W. Wietgrefe, Shelby L. O’connor, Luiz Pianowski, Ashley T. Haase, Carine Van Lint, Robert F. Siliciano, Janice E. Clements, "Reactivation of simian immunodeficiency virus reservoirs in the brain of virally suppressed macaques :", AIDS, LONDON, GB, GB , (20170101), vol. 31, no. 1, doi:10.1097/QAD.0000000000001267, ISSN 0269-9370, pages 5 - 14, XP055541746
OPPOSITION- Robert F. Siliciano and Warner C. Greene, "HIV Latency", Cold Spring Harbor perspectives in medicine, Cold Spring Harbor, NY : Cold Spring Harbor Laboratory Press, US, US , (20110901), vol. 9, no. 8, doi:10.1101/cshperspect.a007096, ISSN 2157-1422, pages 554 - 567, XP002677137
OPPOSITION- F. Klein, Mouquet H., Dosenovic P., Scheid J. F., Scharf L., Nussenzweig M. C., "Antibodies in HIV-1 Vaccine Development and Therapy", Science, American Association for the Advancement of Science, (20130913), vol. 341, no. 6151, doi:10.1126/science.1241144, ISSN 00368075, pages 1199 - 1204, XP055079419
OPPOSITION- Barouch Dan H., Deeks Steven G., "Immunologic strategies for HIV-1 remission and eradication", Science, American Association for the Advancement of Science, US, US , (20140711), vol. 345, no. 6193, doi:10.1126/science.1255512, ISSN 0036-8075, pages 169 - 174, XP055957921
OPPOSITION- Wen-Han Yu, Su David, Torabi Julia, Fennessey Christine M., Shiakolas Andrea, Lynch Rebecca, Chun Tae-Wook, Doria-Rose Nicole, Alter Galit, Seaman Michael S., Keele Brandon F., Lauffenburger Douglas A., Julg Boris, "Predicting the broadly neutralizing antibody susceptibility of the HIV reservoir", JCI Insight, (20190905), vol. 4, no. 17, doi:10.1172/jci.insight.130153, page e130153, XP055634712
OPPOSITION- Ramesh Akkina, Bradford K. Berges, Brent E. Palmer, Leila Remling, C. Preston Neff, Jes Kuruvilla, Elizabeth Connick, Joy Folkvord, Kathy Gagliardi, Afework Kassu, Sarah R. Akkina, "Humanized Rag1−/−γc−/− Mice Support Multilineage Hematopoiesis and Are Susceptible to HIV-1 Infection via Systemic and Vaginal Routes", PLoS ONE, vol. 6, no. 6, doi:10.1371/journal.pone.0020169, page e20169, XP055166718
OPPOSITION- Jean-Philippe Julien, Devin Sok, Reza Khayat, Jeong Hyun Lee, Katie J. Doores, Laura M. Walker, Alejandra Ramos, Devan C. Diwanji, Robert Pejchal, Albert Cupo, Umesh Katpally, Rafael S. Depetris, Robyn L. Stanfield, Ryan Mcbride, Andre J. Marozsan, James C. Paulson, Rogier W. Sanders, John P. Moore, Dennis R. Burton, Pascal Poignard, Andrew B. Ward, Ian A. Wilson, "Broadly Neutralizing Antibody PGT121 Allosterically Modulates CD4 Binding via Recognition of the HIV-1 gp120 V3 Base and Multiple Surrounding Glycans", PLoS Pathogens, vol. 9, no. 5, doi:10.1371/journal.ppat.1003342, page e1003342, XP055328825
OPPOSITION- Devin Sok, Uri Laserson, Jonathan Laserson, Yi Liu, Francois Vigneault, Jean-Philippe Julien, Bryan Briney, Alejandra Ramos, Karen F. Saye, Khoa Le, Alison Mahan, Shenshen Wang, Mehran Kardar, Gur Yaari, Laura M. Walker, Birgitte B. Simen, Elizabeth P. St. John, Po-Ying Chan-Hui, Kristine Swiderek, Stephen H. Kleinstein, Galit Alter, Michael S. Seaman, Arup K. Chakraborty, Daphne Koller, Ian A. Wilson, George M. Church, Dennis R. Burton, Pascal Poignard, "The Effects of Somatic Hypermutation on Neutralization and Binding in the PGT121 Family of Broadly Neutralizing HIV Antibodies", PLoS Pathogens, vol. 9, no. 11, doi:10.1371/journal.ppat.1003754, page e1003754, XP055362599
OPPOSITION- Chen W; Ying T; Dimitrov D S, "Antibody-based candidate therapeutics against HIV-1: Implications for virus eradication and vaccine design", EXPERT OPINION ON BIOLOGICAL THERAPY, Informa Healthcare, (20130501), vol. 13, no. 5, doi:10.1517/14712598.2013.761969, ISSN 1471-2598, pages 657 - 671, XP009177070
OPPOSITION- Peter-Christian Klöhn, Wuellner Ulrich, Zizlsperger Nora, Zhou Yu, Tavares Daniel, Berger Sven, Zettlitz Kirstin A., Proetzel Gabriele, Yong May, Begent Richard H.J., Reichert Janice M., "IBC’s 23nd Annual Antibody Engineering, 10th Annual Antibody Therapeutics International Conferences and the 2012 Annual Meeting of The Antibody Society: December 3–6, 2012, San Diego, CA", mAbs, (20130301), vol. 5, no. 2, doi:10.4161/mabs.23655, ISSN 19420862, pages 178 - 201, XP055070468
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