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Method For Purification Of Retinal Pigment Epithelial Cells - EP3056564

The patent EP3056564 was granted to Healios KK on Sep 11, 2024. The application was originally filed on Oct 9, 2014 under application number EP14852053A. The patent is currently recorded with a legal status of "Patent Maintained As Amended".

EP3056564

HEALIOS KK
Application Number
EP14852053A
Filing Date
Oct 9, 2014
Status
Patent Maintained As Amended
Aug 8, 2024
Grant Date
Sep 11, 2024
External Links
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STRAWMANApr 20, 2022POTTER CLARKSON -

Patent Citations (15) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication NumberPublication Link
DESCRIPTIONUS2013224156
DESCRIPTIONWO2005123902
DESCRIPTIONWO2011043405
INTERNATIONAL-SEARCH-REPORTJP2012080821
INTERNATIONAL-SEARCH-REPORTWO2008129554
INTERNATIONAL-SEARCH-REPORTWO2011043405
INTERNATIONAL-SEARCH-REPORTWO2012115244
INTERNATIONAL-SEARCH-REPORTWO2013069503
OPPOSITIONEP3056563
OPPOSITIONJP2013212345
OPPOSITIONUS2013196369
SEARCHEP1947170
SEARCHSG192878
SEARCHUS2013196369
SEARCHWO2008129554

Non-Patent Literature (NPL) Citations (30) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference TextLink
OPPOSITION- Anni Sorkio, Heidi Hongisto, Kai Kaarniranta, Hannu Uusitalo, Kati Juuti-Uusitalo, Heli Skottman, "Structure and Barrier Properties of Human Embryonic Stem Cell–Derived Retinal Pigment Epithelial Cells Are Affected by Extracellular Matrix Protein Coating", Tissue Engineering Part A, Mary Ann Liebert, Inc., (20140120), doi:10.1089/ten.tea.2013.0049, ISSN 19373341, page 140120073644000-
OPPOSITION- Curriculum vitae of Dr Radeke-
OPPOSITION- Declaration of Dr Radeke-
OPPOSITION- Declaration of I.Klimanskaya-
OPPOSITION- Declaration of Masanori Sawada Ph.D.-
OPPOSITION- English translation of the application as filed -
OPPOSITION- KLIMANSKAYA IRINA, ET AL, "Derivation and comparative assessment of retinal pigment epithelium from human embryonic stem cells using transcriptomics", CLONING AND STEM CELLS, MARY ANN LIEBERT, LARCHMONT, US, US , (20041001), vol. 6, no. 3, ISSN 1536-2302, pages 217 - 245-
OPPOSITION- KLIMANSKAYA IRINA, ET AL, "Derivation and comparative assessment of retinal pigment epithelium from human embryonic stem cells using transcriptomics", CLONING AND STEM CELLS, MARY ANN LIEBERT, LARCHMONT, US, US , (20041001), vol. 6, no. 3, ISSN 1536-2302, pages 217 - 245, XP002528297-
OPPOSITION- Mandai et al. (2017) New England Journal of Medicine 376:1038-1046 (referred to in D13)-
OPPOSITION- Miyazaki et al. (2012), Nature Communications, 3:1236, Supplementary Material-
OPPOSITION- Miyazaki et al. Nature Communications. 2012-
OPPOSITION- OSAKADA FUMITAKA, ET AL, "In vitro differentiation of retinal cells from human pluripotent stem cells by small-molecule induction", JOURNAL OF CELL SCIENCE, Company of Biologists Limited, Cambridge, Cambridge , (20090901), vol. 122, no. 17, doi:10.1242/JCS.050393, ISSN 0021-9533, pages 3169 - 3179-
OPPOSITION- Rowland Teisha J., Blaschke Alison J., Buchholz David E., Hikita Sherry T., Johnson Lincoln V., Clegg Dennis O., "Differentiation of human pluripotent stem cells to retinal pigmented epithelium in defined conditions using purified extracellular matrix proteins : Effects of substrates on RPE differentiation from human pluripotent stem cells", JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, John Wiley & Sons, US, US , (20130801), vol. 7, no. 8, doi:10.1002/term.1458, ISSN 1932-6254, pages 642 - 653-
OPPOSITION- Second Declaration of Dr Klimanskaya-
OPPOSITION- Second Declaration of Dr Monte Radeke-
OPPOSITION- Supplementary material protocol to Mandai et al. (2017) New England Journal of Medicine 376:1038-1046 (referred to in D13)-
OPPOSITION- Rowland Teisha J., Blaschke Alison J., Buchholz David E., Hikita Sherry T., Johnson Lincoln V., Clegg Dennis O., "Differentiation of human pluripotent stem cells to retinal pigmented epithelium in defined conditions using purified extracellular matrix proteins : Effects of substrates on RPE differentiation from human pluripotent stem cells", JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, John Wiley & Sons, US, US , (20130801), vol. 7, no. 8, doi:10.1002/term.1458, ISSN 1932-6254, pages 642 - 653, XP055918017
OPPOSITION- Takamichi Miyazaki, Futaki Sugiko, Suemori Hirofumi, Taniguchi Yukimasa, Yamada Masashi, Kawasaki Miwa, Hayashi Maria, Kumagai Hideaki, Nakatsuji Norio, Sekiguchi Kiyotoshi, Kawase Eihachiro, "Laminin E8 fragments support efficient adhesion and expansion of dissociated human pluripotent stem cells", Nature Communications, (20121204), vol. 3, no. 1236, doi:10.1038/ncomms2231, pages 1 - 10, XP055055638
OPPOSITION- Mandai Michiko, Watanabe Akira, Kurimoto Yasuo, Hirami Yasuhiko, Morinaga Chikako, Daimon Takashi, Fujihara Masashi, Akimaru Hiroshi, Sakai Noriko, Shibata Yumiko, Terada Motoki, Nomiya Yui, Tanishima Shigeki, Nakamura Masahiro, Kamao Hiroyuki, Sugita Sunao, Onishi Akishi, Ito Tomoko, Fujita Kanako, Kawamata Shin, Go Masahiro J., Shinohara Chikara, Hata Ken-Ichiro, Sawada Masanori, Yamamoto Midori, Ohta Sachiko, Ohara Yasuo, Yoshida Kenichi, Kuwahara Junko, Kitano Yuko, Amano Naoki, Umekage Masafumi, Kitaoka Fumiyo, Tanaka Azusa, Okada Chihiro, Takasu Naoko, Ogawa Seishi, Yamanaka Shinya, Takahashi Masayo, "Autologous Induced Stem-Cell-Derived Retinal Cells for Macular Degeneration", The New England journal of medicine, Massachusetts Medical Society, US, US , (20170316), vol. 376, no. 11, doi:10.1056/NEJMoa1608368, ISSN 0028-4793, pages 1038 - 1046, XP055782260
OPPOSITION- Michiko Mandai, "Protocol. Autologous Induced Stem-Cell-Derived Retinal Cells for Macular Degeneration", The New England journal of medicine, Massachusetts Medical Society, US, US , (20170316), vol. 376, no. 11, doi:10.1056/NEJMoa1608368, ISSN 0028-4793, XP093154096
OPPOSITION- Anni Sorkio, Heidi Hongisto, Kai Kaarniranta, Hannu Uusitalo, Kati Juuti-Uusitalo, Heli Skottman, "Structure and Barrier Properties of Human Embryonic Stem Cell–Derived Retinal Pigment Epithelial Cells Are Affected by Extracellular Matrix Protein Coating", Tissue Engineering Part A, Mary Ann Liebert, Inc., (20140120), doi:10.1089/ten.tea.2013.0049, ISSN 19373341, page 140120073644000, XP055108412
OPPOSITION- OSAKADA FUMITAKA, ET AL, "In vitro differentiation of retinal cells from human pluripotent stem cells by small-molecule induction", JOURNAL OF CELL SCIENCE, Company of Biologists Limited, Cambridge, Cambridge , (20090901), vol. 122, no. 17, doi:10.1242/JCS.050393, ISSN 0021-9533, pages 3169 - 3179, XP002604161
SEARCH- HIGUCHI A ET AL, "Differentiation ability of adipose-derived stem cells separated from adipose tissue by a membrane filtration method", JOURNAL OF MEMBRANE SCIENCE, ELSEVIER BV, NL, vol. 366, no. 1-2, ISSN 0376-7388, (20110101), pages 286 - 294, (20101014), XP027525109 [A] 1-10 * the whole document *-
SEARCH- PENG SHAOMIN; QIU CAIHONG; LI LINA; ADELMAN RON A; RIZZOLO LAWRENCE J, "Tight Junctions of RPE Derived from Human Embryonic Stem Cells", ARVO ANNUAL MEETING ABSTRACT SEARCH AND PROGRAM PLANNER, (20110502), XP055197442 [X] 11,12 * abstract * [A] 1-10-
SEARCH- RODIN SERGEY ET AL, "Long-term self-renewal of human pluripotent stem cells on human recombinant laminin-511", NATURE BIOTECHNOLOGY, GALE GROUP INC, US, (20100601), vol. 28, no. 6, ISSN 1087-0156, pages 611 - 615, XP009135150 [A] 1-9 * page 611 - page 612 * * page 614 *-
SEARCH- TEISHA J. ROWLAND ET AL, "Differentiation of human pluripotent stem cells to retinal pigmented epithelium in defined conditions using purified extracellular matrix proteins", JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, (20130818), vol. 7, no. 8, doi:10.1002/term.1458, ISSN 1932-6254, pages 642 - 653, XP055121216 [XD] 11,12 * page 643, column l, paragraph 4 - page 644, column l, paragraph 1 * * page 645; table 1 * * page 646, column l * * page 651 * [A] 1-10
SEARCH- TAKAMICHI MIYAZAKI ET AL, "Laminin E8 fragments support efficient adhesion and expansion of dissociated human pluripotent stem cells", NATURE COMMUNICATIONS, (20121204), vol. 3, doi:10.1038/ncomms2231, page 1236, XP055055638 [Y] 7 * page 2, column r * * page 8, column r - page 9, column l * [A] 2
SEARCH- YANG ZHENGLIN ET AL, "Toll-like receptor 3 and geographic atrophy in age-related macular degeneration", NEW ENGLAND JOURNAL OF MEDICINE, THE - NEJM, MASSACHUSETTS MEDICAL SOCIETY, US, vol. 359, no. 14, doi:10.1056/NEJMOA0802437, ISSN 1533-4406, (20081002), pages 1456 - 1463, (20080827), XP002584685 [A] 1-12 * the whole document *
SEARCH- TAKUYA KURODA ET AL, "Highly Sensitive In Vitro Methods for Detection of Residual Undifferentiated Cells in Retinal Pigment Epithelial Cells Derived from Human iPS Cells", PLOS ONE, (20120517), vol. 7, no. 5, doi:10.1371/journal.pone.0037342, page e37342, XP055382467 [X] 11,12 * page 2 * * page 8; table 1 * [A] 1-10
SEARCH- YU ZHU ET AL, "Three-Dimensional Neuroepithelial Culture from Human Embryonic Stem Cells and Its Use for Quantitative Conversion to Retinal Pigment Epithelium", PLOS ONE, (20130124), vol. 8, no. 1, doi:10.1371/journal.pone.0054552, page e54552, XP055332448 [X] 11,12 * page 10 * [A] 1-10

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