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Methods For Controlling Blood Pharmacokinetics Of Antibodies - EP3056568

The patent EP3056568 was granted to Chugai Seiyaku Kabushiki Kaisha on Sep 15, 2021. The application was originally filed on Mar 30, 2007 under application number EP15196240A. The patent is currently recorded with a legal status of "Granted And Under Opposition".

EP3056568

CHUGAI SEIYAKU KABUSHIKI KAISHA
Application Number
EP15196240A
Filing Date
Mar 30, 2007
Status
Granted And Under Opposition
Aug 13, 2021
Publication Date
Sep 15, 2021
External Links
Slate, Register, Google Patents

Patent Summary

Methods for controlling the blood half-life of antibodies by modifying surface-exposed amino acid residues in the variable regions, without affecting antibody structure or function. The modification involves amino acid substitutions that shift the isoelectric point (pI) of the antibody, enabling control of pharmacokinetics in blood. The methods are applicable to humanized, chimeric, and human antibodies, and can be used to prolong or reduce the half-life of antibodies in blood.

Patent Family

Patent Family

Patent Oppositions (2)

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NOVO NORDISKJun 15, 2022J A KEMPADMISSIBLE
STRAWMANJun 14, 2022PLASSERAUDWITHDRAWN

Patent Citations (30) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication Number
DESCRIPTIONJP20050112514
DESCRIPTIONEP0125023
DESCRIPTIONEP0239400
DESCRIPTIONJPH0159878B
DESCRIPTIONJPH10504970
DESCRIPTIONWO2005035756
DESCRIPTIONWO9201047
DESCRIPTIONWO9203918
DESCRIPTIONWO9219759
DESCRIPTIONWO9220791
DESCRIPTIONWO9306213
DESCRIPTIONWO9311236
DESCRIPTIONWO9319172
DESCRIPTIONWO9402602
DESCRIPTIONWO9501438
DESCRIPTIONWO9515388
DESCRIPTIONWO9515393
DESCRIPTIONWO9602576
DESCRIPTIONWO9633735
DESCRIPTIONWO9634096
DESCRIPTIONWO9813388
DESCRIPTIONWO9846777
DESCRIPTIONWO9951743
EXAMINATIONUS2006057149
EXAMINATIONWO2005121180
OPPOSITIONEP0329185
OPPOSITIONEP2006381
OPPOSITIONEP3056568
OPPOSITIONUS2005244403
OPPOSITIONWO9803546

Dossier Documents

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    Description

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