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Assays For Determining Plasma Kallikrein System Biomarkers - EP3060582

The patent EP3060582 was granted to Dyax on Sep 23, 2020. The application was originally filed on Oct 17, 2014 under application number EP14856778A. The patent is currently recorded with a legal status of "Opposition Rejected".

EP3060582

DYAX
Application Number
EP14856778A
Filing Date
Oct 17, 2014
Status
Opposition Rejected
May 19, 2023
Grant Date
Sep 23, 2020
External Links
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LEDERER & KELLER PATENTANWALTE PARTNERSCHAFT MBBJun 23, 2021 -

Patent Citations (33) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication NumberPublication Link
DESCRIPTIONEP0210029
DESCRIPTIONUS2011086801
DESCRIPTIONUS2011154517
DESCRIPTIONUS2011200611
DESCRIPTIONUS2012201756
DESCRIPTIONUS4985354
DESCRIPTIONUS5795865
DESCRIPTIONUS5994125
DESCRIPTIONUS6057287
DESCRIPTIONUS6242210
DESCRIPTIONUS6333402
DESCRIPTIONUS6913900
DESCRIPTIONUS7064107
DESCRIPTIONUS7276480
DESCRIPTIONUS7628983
DESCRIPTIONUS7811991
DESCRIPTIONUS7851442
DESCRIPTIONUS8124586
DESCRIPTIONUS8283321
DESCRIPTIONWO2012170945
INTERNATIONAL-SEARCH-REPORTUS2005223416
INTERNATIONAL-SEARCH-REPORTUS2008299549
INTERNATIONAL-SEARCH-REPORTUS2011318359
INTERNATIONAL-SEARCH-REPORTWO2006101387
OPPOSITIONEP0210029
OPPOSITIONUS2011154517
OPPOSITIONUS4985354
SEARCHEP0210029
SEARCHUS2011154517
SEARCHUS4985354
SEARCHUS6242210
SEARCHUS6913900
SEARCHWO2012170945

Non-Patent Literature (NPL) Citations (20) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference TextLink
OPPOSITION- Berrettini M; Et Al, "Detection of In Vitro and In Vivo Cleavage of High Molecular Weight Kininogen in Human Plasma by Immunoblotting With Monoclonal Antibodies", Blood, (19860000), vol. 68, no. 2, pages 455 - 462, XP055335425-
OPPOSITION- Dr. Y.S. Babu Ms. Ramanda Wilson Dr. Jianwen Zhang Dr. Melanie Cornpropst Dr. Phil Collis Dr. William Sheridan, "A Simple, Sensitive and Selective Fluorogenic Assay To Monitor Plasma Kallikrein Inhibitory Activity Of BCX4161 In Activated Plasma", J Allergy Clin Immunol, vol. 133, no. 2, (20140201), URL: https://www.jacionline.org/article/S0091-6749(13)02071-X/fulltext#relatedArticles-
OPPOSITION- Faucette Ryan R; Cicardi Marco; Suffritti Chiara; Kenniston Jon A; Sexton Daniel J; Adelman Burt, "A Biomarker Assay For The Detection Of Contact System Activation", Blood, (20131115), vol. 122, no. 21, page 2347, XP055335424-
OPPOSITION- Jianwen Zhang, Debra Kellogg, Ramanda Wilson, Leigh Harman, Shanta Bantia, Y. S. Babu, "750 / A Simple, Sensitive and Selective Fluorogenic Assay to Monitor Kallikrein Activity in Activated Plasma", J Allergy Clin Immunol, (20130200), vol. 131, no. 2, XP055824535-
OPPOSITION- Joseph K; Tuscano T B; Kaplan A P, "Studies of the mechanisms of bradykinin generation in hereditary angioedema plasma", Annals of Allergy, Asthma & immunology, (20080900), vol. 101, pages 279 - 286, XP026960155-
OPPOSITION- Reddigari S R; Kaplan A P, "Monoclonal antibody to human high-molecular-weight kininogen recognizes its prekallikrein binding site and inhibits its coagulant activity", Blood, (19890000), vol. 74, no. 2, pages 695 - 702, XP055346722-
OPPOSITION- Sesha Reddigari and Allen P. Kaplan, "Cleavage of Human High-Molecular Weight Kininogen by Purified Kallikreinsand Upon Contact Activation of Plasma", Blood, (19880000), vol. 71, no. 5, pages 1334 - 1340, XP055824534-
OPPOSITION- SHANTA BANTIA et al., "756/ BCX-4161, a Small Molecule and Orally Bioavailable Plasma Kallikrein Inhibitor for the Treatment of Hereditary Angioedema", J Allergy Clin Immunol, (20130200), vol. 131, no. 2, XP055824536-
OPPOSITION- Veloso; Silver; Hahn; Colman, "A monoclonal anti-human plasma prekallikrein antibody that inhibits activation of prekallikrein by factor XIIa on a surface", Blood, (19870000), vol. 70, no. 4, pages 1053 - 1062, XP055036344-
OPPOSITION- Reddigari S; Kaplan A P, "Quantification of human high molecular weight kininogen by immunoblotting with a monoclonal anti-light chain antibody", Journal of Immunological Methods, (19890000), vol. 119, pages 19 - 25, XP023656916
OPPOSITION- CUGNO M. et al., "Activation of factor XII and cleavage of high molecular weight kininogen during acute attacks in hereditary and acquired C1-inhibitor deficiencies", Immunopharmacology, (19960000), vol. 33, no. 1-3, pages 361 - 364, XP002302326
OPPOSITION- Page J D; Dela Cadena R A; Humphries J E; Colman R W, "An autoantibody to human plasma prekallikrein blocks activation of the contact system", British Journal of Haemotology, (19940000), vol. 87, pages 81 - 86, XP055347009
OPPOSITION- Federica Defendi; Delphine Charignon; Arije Ghannam; Remi Baroso; Françoise Csopaki; Marion Allegret-Cadet; Denise Ponard; Bertrand Favier; Sven Cichon; Brigitte Nicolie; Olivier Fain; Ludovic Martin; Christian Drouet, "Enzymatic Assays for the Diagnosis of Bradykinin-Dependent Angioedema", PLOS ONE, (20130800), vol. 8, no. 8, page e70140, XP055346505
SEARCH- JOSEPH K ET AL, "Studies of the mechanisms of bradykinin generation in hereditary angioedema plasma", ANNALS OF ALLERGY, ASTHMA & IMMUNOLOGY, ARLINGTON HEIGHTS, IL, US, vol. 101, no. 3, ISSN 1081-1206, (20080901), pages 279 - 286, (20080901), XP026960155 [X] 1,3,6-8,11,12,14 * the whole document, in particular abstract; figure 2 *-
SEARCH- M. BERRETTINI ET AL, "Detection of In Vitro and In Vivo Cleavage of High Molecular Weight Kininogen in Human Plasma by Immunoblotting With Monoclonal Antibodies Address reprint requests to", BLOOD, (19860801), vol. 68, no. 2, pages 455 - 462, XP055335425 [X] 1,3,6-8,11,12,14 * the whole document, in particular abstract; figures 4-6 *-
SEARCH- M Cugno ET AL, "Activation of the coagulation cascade in C1-inhibitor deficiencies", Blood, UNITED STATES, vol. 89, no. 9, (19970501), pages 3213 - 3218, URL: http://www.bloodjournal.org/content/bloodjournal/89/9/3213.full.pdf, XP055346366 [X] 1,3,6-8,11,12,14 * the whole document, in particular abstract; page 3214, paragraph spanning columns; page 3215, first full paragraph; figure 2 *-
SEARCH- S R Reddigari ET AL, "Monoclonal antibody to human high-molecular-weight kininogen recognizes its prekallikrein binding site and inhibits its coagulant activity", Blood, UNITED STATES, (19890801), pages 695 - 702, URL: http://www.bloodjournal.org/content/bloodjournal/74/2/695.full.pdf, XP055346722 [X] 1,2,11-13 * the whole document, in particular abstract; page 696, column 1, section "activation of plasma" to column 2, section "immunoblotting"; page 698, paragraph spanning columns to page 699, column 2, line 3; figures 6-8 *-
SEARCH- REDDIGARI S ET AL, "Quantification of human high molecular weight kininogen by immunoblotting with a monoclonal anti-light chain antibody", JOURNAL OF IMMUNOLOGICAL METHODS, ELSEVIER SCIENCE PUBLISHERS B.V.,AMSTERDAM, NL, vol. 119, no. 1, doi:10.1016/0022-1759(89)90376-1, ISSN 0022-1759, (19890421), pages 19 - 25, (19890421), XP023973489 [X] 1,6,11,12 * the whole document, in particular abstract; page 20, section "activation of plasma"; page 21, column 2, line 1 to page 23, column 1, line 2; figures 3, 4 *
SEARCH- J. D. PAGE ET AL, "An autoantibody to human plasma prekallikrein blocks activation of the contact system", BRITISH JOURNAL OF HAEMATOLOGY, GB, (19940501), vol. 87, no. 1, doi:10.1111/j.1365-2141.1994.tb04874.x, ISSN 0007-1048, pages 81 - 86, XP055347009 [X] 1,2,11-13 * the whole document, in particular abstract; page 85, column 1, last paragraph; figures 3, 4 *
SEARCH- FEDERICA DEFENDI ET AL, "Enzymatic Assays for the Diagnosis of Bradykinin-Dependent Angioedema", PLOS ONE, (20130805), vol. 8, no. 8, doi:10.1371/journal.pone.0070140, page e70140, XP055346505 [X] 1,3,6-8,11,12,14,15 * the whole document, in particular abstract; sections 1.3, 3, 5, 7; page 6, last four lines of "discussion"; figures 2, 4, 6 * [I] 4,5,9,10,13

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