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Adrenomedullin Binder For Use In Therapy Of Cancer - EP3082858

The patent EP3082858 was granted to Angiobiomed on Jan 27, 2021. The application was originally filed on Dec 19, 2014 under application number EP14830958A. The patent is currently recorded with a legal status of "Revoked".

EP3082858

ANGIOBIOMED
Application Number
EP14830958A
Filing Date
Dec 19, 2014
Status
Revoked
Aug 4, 2023
Grant Date
Jan 27, 2021
External Links
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SCHIWECK WEINZIERL KOCH PATENTANWALTE PARTNERSCHAFT MBBOct 26, 2021SCHIWECK WEINZIERL KOCH PATENTANWALTE PARTNERSCHAFT MBBADMISSIBLE

Patent Citations (3) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication Number
EXAMINATIONWO2013072513
INTERNATIONAL-SEARCH-REPORTWO9707214
OPPOSITIONWO9707214

Non-Patent Literature (NPL) Citations (14) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference Text
EXAMINATION- TORRES ET AL, "The immunoglobulin constant region contributes to affinity and specificity", TRENDS IN IMMUNOLOGY, ELSEVIER LTD. * TRENDS JOURNALS, GB, (20080110), vol. 29, no. 2, doi:10.1016/J.IT.2007.11.004, ISSN 1471-4906, pages 91 - 97, XP022455732
EXAMINATION- XIA YUMIN ET AL, "The constant region affects antigen binding of antibodies to DNA by altering secondary structure", MOLECULAR IMMUNOLOGY, PERGAMON, GB, (20130508), vol. 56, no. 1, doi:10.1016/J.MOLIMM.2013.04.004, ISSN 0161-5890, pages 28 - 37, XP028566984
EXAMINATION- M. TORRES ET AL, "The Immunoglobulin Heavy Chain Constant Region Affects Kinetic and Thermodynamic Parameters of Antibody Variable Region Interactions with Antigen", JOURNAL OF BIOLOGICAL CHEMISTRY, (20070312), vol. 282, no. 18, doi:10.1074/jbc.M700661200, ISSN 0021-9258, pages 13917 - 13927, XP055108720
INTERNATIONAL-SEARCH-REPORT- OUAFIK L; SAUZE S; BOUDOURESQUE F; CHINOT 0; DELFINO C; FINA F; VUAROQUEAUX V; DUSSERT C; PALMARI J; DUFOUR H ET AL., "Neutralization of adrenomedullin inhibits the growth of human glioblastoma cell lines in vitro and suppresses tumor xenograft growth in vivo", THE AMERICAN JOURNAL OF PATHOLOGY, (2002), vol. 160, no. 4, pages 1279 - 1292, XP002421261 [ID] 1-13 * page 1282, column r, paragraph 2 * * page 1283, column l, paragraph 3 * * page 1288, column r, paragraph 2 * * page 1286, column r, paragraph l; table 2 *
INTERNATIONAL-SEARCH-REPORT- EMILIE NOUGUERÈDE ET AL, "Expression of adrenomedullin in human colorectal tumors and its role in cell growth and invasion in vitro and in xenograft growth in vivo", CANCER MEDICINE, (20130429), vol. 2, no. 2, doi:10.1002/cam4.51, ISSN 2045-7634, pages 196 - 207, XP055110951 [I] 1-13 * page 198, column l, paragraph 1 * * page 202, column l, paragraph 2 - page 203, column r, paragraph 1 *
INTERNATIONAL-SEARCH-REPORT- MILLER MAE JEAN ET AL, "Adrenomedullin expression in human tumor cell lines: Its potential role as an autocrine growth factor", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY, US, (19960901), vol. 271, no. 38, doi:10.1074/JBC.271.38.23345, ISSN 0021-9258, pages 23345 - 23351, XP002184272 [I] 1-13 * page 23346, column l, paragraph 4 * * page 23348, column r, paragraph 2; table 1 *
INTERNATIONAL-SEARCH-REPORT- Alfredo Martínez ET AL, "The effects of adrenomedullin overexpression in breast tumor cells", Journal of the National Cancer Institute, United States, doi:10.1093/jnci/94.16.1226, (20020821), pages 1226 - 1237, URL: http://www.ncbi.nlm.nih.gov/pubmed/12189226, (20140401), XP055110963 [A] 1-13 * the whole document *
INTERNATIONAL-SEARCH-REPORT- BERENGUER-DAIZÉ CAROLINE ET AL, "Adrenomedullin blockade suppresses growth of human hormone-independent prostate tumor xenograft in mice", CLINICAL CANCER RESEARCH, THE AMERICAN ASSOCIATION FOR CANCER RESEARCH, US, vol. 19, no. 22, doi:10.1158/1078-0432.CCR-13-0691, ISSN 1078-0432, (20131115), pages 6138 - 6150, (20131007), XP008168601 [I] 1-13 * page 6139, column r, line l; figure 3 * * page 6143, column r, paragraph l - page 6145, column r, paragraph 1 *
OPPOSITION- Roy Jefferis, "Isotype and glycoform selection for antibody therapeutics", ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, Academic Press, US, US , (20121001), vol. 526, no. 2, doi:10.1016/j.abb.2012.03.021, ISSN 0003-9861, pages 159 - 166, XP055292895
OPPOSITION- MILLER MAE JEAN ET AL, "Adrenomedullin expression in human tumor cell lines: Its potential role as an autocrine growth factor.", Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, US, US , (19960901), vol. 271, no. 38, doi:10.1074/jbc.271.38.23345, ISSN 0021-9258, pages 23345 - 23351, XP002184272
OPPOSITION- HA Watkins; M Au; R Bobby; JK Archbold; N Abdul‐Manan; JM Moore; MJ Middleditch; GM Williams; MA Brimble; AJ Dingley; DL Hay, "Identification of key residues involved in adrenomedullin binding to the AM1 receptor", BRITISH JOURNAL OF PHARMACOLOGY, Wiley-Blackwell, UK, UK , (20130412), vol. 169, no. 1, doi:10.1111/bph.12118, ISSN 0007-1188, pages 143 - 155, XP071123612
OPPOSITION- Joachim Struck, Frauke Hein, Siegmund Karasch, Andreas Bergmann, "Epitope specificity of anti-Adrenomedullin antibodies determines efficacy of mortality reduction in a cecal ligation and puncture mouse model", Intensive Care Medicine Experimental, (20130101), vol. 1, no. 1, doi:10.1186/2197-425X-1-3, ISSN 2197-425X, page 3, XP055460518
OPPOSITION- Baranello Cinzia, Mariani Marisa, Andreoli Mirko, Fanelli Mara, Martinelli Enrica, Ferrandina Gabriella, Scambia Giovanni, Shahabi Shohreh, Ferlini Cristiano, "Adrenomedullin in Ovarian Cancer: Foe In Vitro and Friend In Vivo?", PLoS ONE, (20120101), vol. 7, no. 7, doi:10.1371/journal.pone.0040678, page e40678, XP055859960
OPPOSITION- Kim Jee-Youn, Park Won-Do, Lee Sun, Park Jae-Hoon, "Adrenomedullin is involved in the progression of colonic adenocarcinoma", Molecular Medicine Reports, Spandidos Publications, GR, GR , (20121101), vol. 6, no. 5, doi:10.3892/mmr.2012.1045, ISSN 1791-2997, pages 1030 - 1034, XP055859954

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