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Agents For Use In The Treatment Of Retinal Inflammation - EP3096781

The patent EP3096781 was granted to Centre National DE LA Recherche Scientifique Cnrs on Nov 2, 2022. The application was originally filed on Jan 22, 2015 under application number EP15701194A. The patent is currently recorded with a legal status of "Granted And Under Opposition".

EP3096781

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
Application Number
EP15701194A
Filing Date
Jan 22, 2015
Status
Granted And Under Opposition
Sep 30, 2022
Grant Date
Nov 2, 2022
External Links
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Patent Citations (8) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication NumberPublication Link
EXAMINATIONEP1990060
EXAMINATIONUS2013195806
INTERNATIONAL-SEARCH-REPORTEP2116530
INTERNATIONAL-SEARCH-REPORTWO2004045507
OPPOSITIONWO2004045507
OPPOSITIONWO2007086490
OPPOSITIONWO2009014263
OPPOSITIONWO2009042677

Non-Patent Literature (NPL) Citations (22) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference TextLink
EXAMINATION- Haruta H ET AL, "Blockade of interleukin-6 signaling suppresses not only th17 but also interphotoreceptor retinoid binding protein-specific Th1 by promoting regulat... - PubMed - NCBI", (20110501), URL: https://www.ncbi.nlm.nih.gov/pubmed/21330657, (20200407), XP055683596-
EXAMINATION- Modesto A. Rojas ET AL, "Interleukin 6 has a Critical Role in Diabetes-induced Retinal Vascular Inflammation and Permeability | IOVS | ARVO Journals", (20110401), URL: https://iovs.arvojournals.org/article.aspx?articleid=2350761, (20200407), XP055683563-
EXAMINATION- MODESTO A. ROJAS; WENBO ZHANG; ZHIMIN XU; DOAN T. NGUYEN; ROBERT W. CALDWELL; RUTH B. CALDWELL, "Interleukin 6 has a Critical Role in Diabetes-induced Retinal Vascular Inflammation and Permeability FRE", INVEST. OPHTHALMOL. VIS. SCI., (20110401), vol. 52, no. 14, doi:https://iovs.arvojournals.org/article.aspx?articleid=2350761-
EXAMINATION- RAMKUMAR H L ET AL, "Retinal ultrastructure of murine models of dry age-related macular degeneration (AMD)", PROGRESS IN RETINAL AND EYE RESEARCH, OXFORD, GB, vol. 29, no. 3, doi:10.1016/J.PRETEYERES.2010.02.002, ISSN 1350-9462, (20100501), pages 169 - 190, (20100303), XP002690745
EXAMINATION- HARUTA H, OHGURO N, FUJIMOTO M, HOHKI S, TERABE F, SERADA S, NOMURA S, NISHIDA K, KISHIMOTO T, NAKA T, "Blockade of interleukin-6 signaling suppresses not only th17 but also interphotoreceptor retinoid binding protein-specific Th1 by promoting regulatory T cells in experimental autoimmune uveoretinitis", INVEST OPHTHALMOL VIS SCI, (20110501), vol. 52, no. 6, doi: 10.1167/iovs.10-6272, pages 3264 - 3271, XP055863955
OPPOSITION- Anonymous, "FDA Approves SYFOVRE™ (pegcetacoplan injection) as the First and Only Treatment for Geographic Atrophy (GA), a Leading Cause of Blindness", (20230217), URL: https://investors.apellis.com/news-releases/news-release-details/fda-approves-syfovretm-pegcetacoplan-injection-first-and-only, XP093182256-
OPPOSITION- Anonymous, "Geographic Atrophy", EyeWiki, (20230725), EyeWiki, URL: https://eyewiki.org/w/index.php?title=Geographic_Atrophy&oldid=96120, XP093182225-
OPPOSITION- Klein Ronald; Knudtson Michael D; Klein Barbara E K; Wong Tien Y; Cotch Mary Frances; Liu Kiang; Cheng Ching Y; Burke Gregory L; Saad Mohammed F; Jacobs David R Jr; Sharrett A Richey, "Inflammation, complement factor h, and age-related macular degeneration: the Multi-ethnic Study of Atherosclerosis.", Ophthalmology, ELSEVIER, AMSTERDAM, NL, AMSTERDAM, NL, (20081001), vol. 115, no. 10, ISSN 0161-6420, pages 1742 - 1749, XP009113836-
OPPOSITION- NOWAK JERZY Z, "Age-related macular degeneration (AMD): pathogenesis and therapy", PHARMACOLOGICAL REPORTS, POLSKA AKADEMIA NAUK, INSTYTUT FARMAKOLOGII, KRAKOW, PL, PL , (20060501), vol. 58, no. 3, ISSN 1734-1140, pages 353 - 363, XP002476990-
OPPOSITION- SEDDON J M, ET AL., "PROGRESSION OF AGE-RELATED MACULAR DEGENERATION", Archives of Ophthalmology, American Medical Association, United States, United States , (20050601), vol. 123, doi:10.1001/archopht.123.6.774, ISSN 0003-9950, pages 774 - 782, XP009068012
OPPOSITION- Rein David B, Wittenborn John S, Zhang Xinzhi, Honeycutt Amanda A, Lesesne Sarah B, Saaddine Jinan, "Forecasting Age-Related Macular Degeneration Through the Year 2050: The Potential Impact of New Treatments", Archives of Ophthalmology, American Medical Association, United States, United States , (20090401), vol. 127, no. 4, doi:10.1001/archophthalmol.2009.58, ISSN 0003-9950, pages 533 - 540, XP009555415
OPPOSITION- Sennlaub Florian, Auvynet Constance, Calippe Bertrand, Lavalette Sophie, Poupel Lucie, Hu Shulong J., Dominguez Elisa, Camelo Serge, Levy Olivier, Guyon Elodie, Saederup Noah, Charo Israel F., Rooijen Nico Van, Nandrot Emeline, Bourges Jean‐louis, Behar‐cohen Francine, Sahel José‐alain, Guillonneau Xavier, Raoul William, Combadiere Christophe, "CCR2+ monocytes infiltrate atrophic lesions in age-related macular disease and mediate photoreceptor degeneration in experimental subretinal inflammation in Cx3crl deficient mice", EMBO Molecular Medicine, Wiley-Blackwell, US, US , (20131101), vol. 5, no. 11, doi:10.1002/emmm.201302692, ISSN 1757-4676, pages 1775 - 1793, XP093182254
OPPOSITION- Yiming Huang; Volker Enzmann; Suzanne T. Ildstad, "Stem Cell-Based Therapeutic Applications in Retinal Degenerative Diseases", Stem Cell Reviews and Reports, Humana Press Inc, New York, New York , (20100922), vol. 7, no. 2, doi:10.1007/s12015-010-9192-8, ISSN 1558-6804, pages 434 - 445, XP019895297
OPPOSITION- Raoul, W. ; Keller, N. ; Rodero, M. ; Behar-Cohen, F. ; Sennlaub, F. ; Combadiere, C., "Role of the chemokine receptor CX3CR1 in the mobilization of phagocytic retinal microglial cells", Journal of Neuroimmunology, ELSEVIER SCIENCE PUBLISHERS BV., NL, NL , (20080731), vol. 198, no. 1-2, doi:10.1016/j.jneuroim.2008.04.014, ISSN 0165-5728, pages 56 - 61, XP022939345
OPPOSITION- Mark E. Pennesi; Martha Neuringer; Robert J. Courtney;, "Animal models of age related macular degeneration", Molecular aspects of medicine, PERGAMON PRESS, OXFORD., GB, GB , vol. 33, no. 4, doi:10.1016/j.mam.2012.06.003, ISSN 0098-2997, pages 487 - 509, XP028400783
OPPOSITION- Leung, K.W. ; Barnstable, C.J. ; Tombran-Tink, J., "Bacterial endotoxin activates retinal pigment epithelial cells and induces their degeneration through IL-6 and IL-8 autocrine signaling", Molecular Immunology, PERGAMON, GB, GB , (20090401), vol. 46, no. 7, doi:10.1016/j.molimm.2008.12.001, ISSN 0161-5890, pages 1374 - 1386, XP026028960
OPPOSITION- Spaide Richard F.; Jaffe Glenn J.; Sarraf David; Freund K. Bailey; Sadda Srinivas R.; Staurenghi Giovanni; Waheed Nadia K.; Chakravarthy Usha; Rosenfeld Philip J.; Holz Frank G.; Souied Eric H.; Cohen Salomon Y.; Querques Giuseppe; Ohno-Matsui Kyoko; Boyer David; Gaudric Alain; Blodi Barbara; Baumal Caroline R.; Li Xiaoxin; Coscas Gabriel J.; Brucker Alexander; Singerman Lawrence; Luthert Phil; Schmitz-Valckenberg Steffen; Schmidt-Erfurth Ursula; Grossniklaus Hans E.; Wilson David J.; Guymer Robyn; Yannuzzi Lawrence A.; Chew Emily Y.; Csaky Karl; Monés Jordi M.; Pauleikhoff Daniel; Tadayoni Ramin; Fujimoto James, "Consensus Nomenclature for Reporting Neovascular Age-Related Macular Degeneration Data Consensus on Neovascular Age-Related Macular Degeneration Nomenclature Study Group", Ophthalmology, ELSEVIER, AMSTERDAM, NL, AMSTERDAM, NL, (20191114), vol. 127, no. 5, doi:10.1016/j.ophtha.2019.11.004, ISSN 0161-6420, pages 616 - 636, XP086141446
OPPOSITION- Jayakrishna Ambati, John P. Atkinson, Bradley D. Gelfand, "Immunology of age-related macular degeneration", Nature Reviews Immunology, Nature Pub. Group, vol. 13, no. 6, doi:10.1038/nri3459, ISSN 14741733, pages 438 - 451, XP055135749
OPPOSITION- SWAROOP ANAND ET AL, "Unraveling a multifactorial late-onset disease: from genetic susceptibility to disease mechanisms for age-related macular degeneration.", ANNUAL REVIEW OF GENOMICS AND HUMAN GENETICS, ANNUAL REVIEWS, US, US , (20090901), vol. 10, doi:10.1146/ANNUREV.GENOM.9.081307.164350, ISSN 1527-8204, pages 19 - 43, XP002584686
OPPOSITION- Rodrigues Eduardo B., "Inflammation in Dry Age-Related Macular Degeneration", OPHTHALMOLOGICA, KARGER, BASEL, CH, CH , (20070401), vol. 221, no. 3, doi:10.1159/000099293, ISSN 0030-3755, pages 143 - 152, XP009555418
OPPOSITION- Combadiere Christophe; Feumi Charles; Raoul William; Keller Nicole; Rodero Mathieu; Pezard Adeline; Lavalette Sophie; Houssier Marianne; Jonet Laurent; Picard Emilie; Debre Patrice; Sirinyan Mirna; Deterre Philippe; Ferroukhi Tania; Cohen Salomon-Yves; Chauvaud Dominique; Jeanny Jean-Claude; Chemtob Sylvain; Behar-Cohen Francine; Sennlaub Florian, "CX3CR1-dependent subretinal microglia cell accumulation is associated with cardinal features of age-related macular degeneration", The Journal of Clinical Investigation, B M J Group, (20071001), vol. 117, no. 10, doi:10.1172/JCI31692, pages 2920 - 2928, XP009122956
OPPOSITION- Levy Olivier, Calippe Bertrand, Lavalette Sophie, Hu Shulong J, Raoul William, Dominguez Elisa, Housset Michael, Paques Michel, Sahel José‐alain, Bemelmans Alexis‐pierre, Combadiere Christophe, Guillonneau Xavier, Sennlaub Florian, "Apolipoprotein E promotes subretinal mononuclear phagocyte survival and chronic inflammation in age‐related macular degeneration", EMBO Molecular Medicine, Wiley-Blackwell, US, US , (20150201), vol. 7, no. 2, doi:10.15252/emmm.201404524, ISSN 1757-4676, pages 211 - 226, XP093182210

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