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Modulation Of Cell Growth And Glycosylation In Recombinant Glycoprotein Production - EP3110961

The patent EP3110961 was granted to F Hoffmann LA Roche on Nov 27, 2019. The application was originally filed on Feb 24, 2015 under application number EP15709430A. The patent is currently recorded with a legal status of "Granted And Under Opposition".

EP3110961

F HOFFMANN LA ROCHE
Application Number
EP15709430A
Filing Date
Feb 24, 2015
Status
Granted And Under Opposition
Oct 25, 2019
Grant Date
Nov 27, 2019
External Links
Slate, Register, Google Patents

Patent Summary

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Patent Family

Patent Oppositions (2)

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ABG LAWAug 27, 2020ABG LAWADMISSIBLE
SCHULZ JUNGHANS PATENTANWALTE PARTGMBBAug 27, 2020SCHULZ JUNGHANS PATENTANWALTE PARTGMBBADMISSIBLE

Patent Citations (37) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication NumberPublication Link
DESCRIPTIONEP0307247
DESCRIPTIONUS2007161084
DESCRIPTIONUS2008081356
DESCRIPTIONUS2009068705
DESCRIPTIONWO2012149197
DESCRIPTIONWO9725428
DESCRIPTIONWO9808934
EXAMINATIONWO2011095596
INTERNATIONAL-SEARCH-REPORTEP1096017
INTERNATIONAL-SEARCH-REPORTUS2007161084
INTERNATIONAL-SEARCH-REPORTWO2008008360
INTERNATIONAL-SEARCH-REPORTWO2008109410
INTERNATIONAL-SEARCH-REPORTWO2011019622
INTERNATIONAL-SEARCH-REPORTWO2013114245
INTERNATIONAL-SEARCH-REPORTWO9961650
OPPOSITIONEP1096017
OPPOSITIONUS2005287666
OPPOSITIONUS2007161084
OPPOSITIONUS2007231895
OPPOSITIONUS2009068705
OPPOSITIONUS4767704
OPPOSITIONWO02066603
OPPOSITIONWO2006026445
OPPOSITIONWO2006108455
OPPOSITIONWO2007070315
OPPOSITIONWO2008008360
OPPOSITIONWO2008055260
OPPOSITIONWO2008109410
OPPOSITIONWO2011019622
OPPOSITIONWO2011095596
OPPOSITIONWO2011134919
OPPOSITIONWO2012147048
OPPOSITIONWO2012149197
OPPOSITIONWO2013114245
OPPOSITIONWO2015051293
OPPOSITIONWO9808934
OPPOSITIONWO9961650

Non-Patent Literature (NPL) Citations (15) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference TextLink
EXAMINATION- SAUER P W ET AL, "A high-yielding, generic fed-batch cell culture process for production of recombinant antibodies", BIOTECHNOLOGY AND BIOENGINEERING, WILEY, US, vol. 67, no. 5, doi:10.1002/(SICI)1097-0290(20000305)67:5<585::AID-BIT9>3.0.CO;2-H, ISSN 0006-3592, (20000305), pages 585 - 597, (20000326), XP002690472
OPPOSITION- A Burgener, M Butler, "3 Medium Development", CELL CULTURE TECHNOLOGY FOR PHARMACEUTICAL AND CELL-BASED THERAPIES, TAYLOR & FRANCIS , (20060101), pages 41 - 79, ISBN 978-0-8247-5334-4, XP055454641-
OPPOSITION- SHANTHA RAJU, "Glycosylation Variations with Expression Systems and Their Impact on Biological Activity of Therapeutic Immunoglobulins", Bio Process International, (20030000), pages 44 - 53, XP002738482-
OPPOSITION- CROWELL et al., "Amino Acid and Manganese Supplementation Modulates the Glycosylation State of Erythropoietin in a CHO Culture System", Biotechnology and Bioengineering, (20070215), vol. 96, no. 3, doi:10.1002/bit.21141, pages 538 - 549, XP002457773
OPPOSITION- PACIS et al., "Effects of Cell Culture Conditions on Antibody N-linked Glycosylation - What Affects High Mannose 5 Glycoform", Biotechnology and Bioengineering, (20110000), vol. 108, no. 10, doi:10.1002/bit.23200, pages 2348 - 58, XP055080567
OPPOSITION- Surve Tanaya, Gadgil Mugdha, "Manganese increases high mannose glycoform on monoclonal antibody expressed in CHO when glucose is absent or limiting: Implications for use of alternate sugars", Biotechnology Progress, American Chemical Society, (20150301), vol. 31, no. 2, doi:10.1002/btpr.2029, ISSN 8756-7938, pages 460 - 467, XP055927999
OPPOSITION- BAI et al., "Role of Iron and Sodium Citrate in Animal Protein-Free CHO Cell Culture Medium on Cell Growth and Monoclonal Antibody Production", Biotechnol. Prog., (20110000), vol. 27, no. 1, doi:10.1002/BTPR.513, pages 209 - 219, XP002678838
OPPOSITION- QIAN et al., "Cell Culture and Gene Transcription Effects of Copper Sulfate on Chinese Hamster Ovary Cells", Biotechnol. Prog., (20110000), vol. 27, no. 4, doi:10.1002/btpr.630, pages 1190 - 1194, XP055135700
OPPOSITION- SAUER P W et al., "A high-yielding, generic fed- batch cell culture process for production of recombinant antibodies", Biotechnology And Bioengineering, (20000305), vol. 67, doi:10.1002/(SICI)1097-0290(20000305)67:5<585::AID-BIT9>3.0.CO;2-H, pages 585 - 597, XP002690472
OPPOSITION- HOSSLER, "Protein Glycosylation Control in Mammalian Cell Culture: Past Precedents and Contemporary Prospects", Advances in Biochemical Engineering/Biotechnology, (20120000), vol. 127, doi:10.1007/10_2011_113, pages 187 - 219, XP055679442
OPPOSITION- RAYNER et al., "A simple and effective method for the removal of trace metal cations from a mammalian culture medium supported with 10% fetal calf serum", BioMetals, (19950000), vol. 8, doi:10.1007/BF00143374, pages 188 - 192, XP055378079
OPPOSITION- KIM SG et al., "Coexpression of folding accessory proteins for production of active cyclodextrin glycosyltransferase of Bacillus macerans in recombinant Escherichia coli", Protein Expr Purif., (20050601), vol. 41, doi:10.1016/j.pep.2005.01.017, pages 426 - 432, XP004875134
OPPOSITION- MUNRO, "What can yeast tell us about N-linked glycosylation in the Golgi apparatus?", FEBS Lett., (20010516), vol. 498, doi:10.1016/S0014-5793(01)02488-7, pages 223 - 227, XP004597910
OPPOSITION- WILDT et al., "The humanization of N- glycosylation pathways in yeast", Nature Review Microbiol., (20050200), vol. 3, doi:10.1038/nrmicro1087, pages 119 - 128, XP009064525
OPPOSITION- HAN Y et al., "Cultivation of recombinant Chinese hamster ovary cells grown as suspended aggregates in stirred vessels", J Biosci Bioeng., (20060000), vol. 102, no. 5, doi:10.1263/jbb.102.430, pages 430 - 435, XP028042354

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