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Methods, Kits, And Systems For Scoring The Immune Response To Cancer By Simultaneous Detection Of Cd3, Cd8, Cd20 And Foxp3 - EP3111221

The patent EP3111221 was granted to Ventana Medical Systems on Jan 19, 2022. The application was originally filed on Feb 20, 2015 under application number EP15706450A. The patent is currently recorded with a legal status of "Patent Maintained As Amended".

EP3111221

VENTANA MEDICAL SYSTEMS
Application Number
EP15706450A
Filing Date
Feb 20, 2015
Status
Patent Maintained As Amended
Dec 17, 2021
Publication Date
Jan 19, 2022
External Links
Slate, Register, Google Patents

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CMS CAMERON MCKENNA NABARRO OLSWANGJul 10, 2019CMS CAMERON MCKENNA NABARRO OLSWANG -

Patent Citations (7) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication Number
INTERNATIONAL-SEARCH-REPORTUS2013330325
OPPOSITIONUS2013260379
OPPOSITIONUS2013330325
OPPOSITIONWO2007045996
OPPOSITIONWO2013107900
OPPOSITIONWO2013186374
OPPOSITIONWO2014005909

Non-Patent Literature (NPL) Citations (25) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference Text
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INTERNATIONAL-SEARCH-REPORT- CIMINO-MATHEWS ASHLEY ET AL, "Metastatic triple-negative breast cancers at first relapse have fewer tumor-infiltrating lymphocytes than their matched primary breast tumors: a pilot study", HUMAN PATHOLOGY, (20131001), vol. 44, no. 10, doi:10.1016/J.HUMPATH.2013.03.010, ISSN 0046-8177, pages 2055 - 2063, XP028719910 [A] 1-15 * the whole document *
INTERNATIONAL-SEARCH-REPORT- GANNON P O ET AL, "Characterization of the intra-prostatic immune cell infiltration in androgen-deprived prostate cancer patients", JOURNAL OF IMMUNOLOGICAL METHODS, ELSEVIER SCIENCE PUBLISHERS B.V.,AMSTERDAM, NL, vol. 348, no. 1-2, doi:10.1016/J.JIM.2009.06.004, ISSN 0022-1759, (20090831), pages 9 - 17, (20090622), XP026470608 [A] 1-15 * the whole document *
INTERNATIONAL-SEARCH-REPORT- C. M. VAN DER LOOS, "Multiple Immunoenzyme Staining: Methods and Visualizations for the Observation With Spectral Imaging", JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY, (20080401), vol. 56, no. 4, doi:10.1369/jhc.2007.950170, ISSN 0022-1554, pages 313 - 328, XP055026599 [A] 1-15 * the whole document *
OPPOSITION- Bindea et al, Immunity, (20130000), vol. 39, pages 792 - 795
OPPOSITION- "Chapter 5: Immunohistochemistry", DEBRA HAWES et al., Modern Surgical Pathology. 2nd ed., Saunders, (20090000), pages 48 - 70, ISBN 978-1-4160-3966-2, XP055624588
OPPOSITION- Grabenbauer Gerhard G. et al, "Tumor-Infiltrating Cytotoxic T Cells but not Regulatory T Cells Predict Outcome in Anal Squamous Cell Carcinoma", Clin Cancer Res, (20060601), vol. 12, no. 11, pages 3355 - 3360
OPPOSITION- HAAS et al., "Stromal regulatory T-cells are associated with a favourable prognosis in gastric cancer of the cardia", BMC Gastroenterology, (20090000), vol. 9, doi:10.1186/1471-230X-9-65, page 65
OPPOSITION- LENG et al., "ELISA and multiplex technology for cytokine measurement in inflammation and ageing research", Journal of Gerontology Series A: Biological Sciences and Medical Sciences, (20080800), vol. 63, no. 8, pages 879 - 884
OPPOSITION- NATTKEMPER et al., "A neural classifier enabling high-throughput topological analysis of lymphocytes in tissue sections", IEEE TRANS INF TECHNOL BIOMED ., (20010000), vol. 5, no. 2, pages 138 - 149, XP011028233
OPPOSITION- STUMPF et al., "Intraepithelial CD 8-positive T lymphocytes predict survival for patients with serous stage III ovarian carcinomas: relevance of clonal selection of T lymphocytes", British Journal of Cancer, (20091103), vol. 101, no. 9, pages 1513 - 1521
OPPOSITION- VAN DER LOOS, "Multiple Immunoenzyme Staining: Methods and Visualizations for the Observation With Spectral Imaging", Journal of Histochemistry & Cytochemistry, (20080000), vol. 56, no. 4, doi:10.1369/jhc.2007.950170, pages 313 - 28
OPPOSITION- ZINGG et al., "Tumour-infiltrating lymphocytes and survival in patients with adenocarcinoma of the oesophagus", European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, (2010526), vol. 36, no. 7, pages 670 - 677
OPPOSITION- ZINGG et al., "Tumour-infiltrating lymphocytes and survival in patients with adenocarcinoma of the oesophagus", European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, (2010526), vol. 36, no. 7, pages 670 - 677, XP027106630
OPPOSITION- CUALING et al., "Virtual flow cytometry' of immunostained lymphocytes on microscopic tissue slides: iHCFlow tissue cytometry", Cytometry. Part B, Clinical cytometry, (20070115), vol. 72B, no. 1, pages 63 - 76, XP055624582
OPPOSITION- KRÜGER et al., "Combat or surveillance? Evaluation of the heterogeneous inflammatory breast cancer microenvironment", The Journal of Pathology, (20130000), vol. 229, no. 4, doi:10.1002/path.4150, pages 569 - 578, XP055181126
OPPOSITION- STUMPF et al., "Intraepithelial CD 8-positive T lymphocytes predict survival for patients with serous stage III ovarian carcinomas: relevance of clonal selection of T lymphocytes", British Journal of Cancer, (20091103), vol. 101, no. 9, pages 1513 - 1521, XP055624581
OPPOSITION- ALYASSIN et al., "Rapid automated cell quantification on HIV microfluidic devices", Lab on a chip, (20091207), vol. 9, no. 23, pages 3364 - 9, XP055624580
OPPOSITION- LENG et al., "ELISA and multiplex technology for cytokine measurement in inflammation and ageing research", Journal of Gerontology Series A: Biological Sciences and Medical Sciences, (20080800), vol. 63, no. 8, pages 879 - 884, XP008154409
OPPOSITION- Jérôme Galon et al, "Type, Density, and Location of Immune Cells Within Human Colorectal Tumors Predict Clinical Outcome (Supporting Online Material)", Science, (20060929), vol. 313, no. 5795, XP055624604
OPPOSITION- GALON et al., "Type, Density, and Location of Immune Cells Within Human Colorectal Tumors Predict Clinical Outcome", Science, (20060929), vol. 313, no. 5795, doi:10.1126/SCIENCE.1129139, pages 1960 - 1964, XP002684010
OPPOSITION- HAAS et al., "Stromal regulatory T-cells are associated with a favourable prognosis in gastric cancer of the cardia", BMC Gastroenterology, (20090000), vol. 9, doi:10.1186/1471-230X-9-65, page 65, XP021057249
OPPOSITION- VAN DER LOOS, "Multiple Immunoenzyme Staining: Methods and Visualizations for the Observation With Spectral Imaging", Journal of Histochemistry & Cytochemistry, (20080000), vol. 56, no. 4, doi:10.1369/jhc.2007.950170, pages 313 - 28, XP055026599
OPPOSITION- PIRICI et al., "Antibody Elution Method for Multiple Immunohistochemistry on Primary Antibodies Raised in the Same Species and of the Same Subtype", The Journal of Histochemistry & Cytochemistry, (20090000), vol. 57, no. 6, doi:10.1369/jhc.2009.953240, pages 567 - 575, XP055014242
OPPOSITION- HALAMA et al., "Estimation of immune cell densities in immune cell conglomerates: an approach for high-throughput quantification", PloS one, (20091116), vol. 4, no. 11, pages e7847.1 - e7847.6, XP002691992

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