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Pharmaceutical Composition Against Chronic Bacterial Infections - EP3129044

The patent EP3129044 was granted to Lysando on Sep 7, 2022. The application was originally filed on Apr 8, 2015 under application number EP15715243A. The patent is currently recorded with a legal status of "Granted And Under Opposition".

EP3129044

LYSANDO
Application Number
EP15715243A
Filing Date
Apr 8, 2015
Status
Granted And Under Opposition
Aug 5, 2022
Grant Date
Sep 7, 2022
External Links
Slate, Register, Google Patents

Patent Summary

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Patent Family

Patent Oppositions (3)

Patent oppositions filed by competitors challenge the validity of a granted patent. These oppositions are typically based on claims of prior art, lack of novelty, or non-obviousness. They are a key part of the process for determining a patent's strength and enforceability.

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STRAWMANJun 7, 2023LEONARDADMISSIBLE
STRAWMANJun 7, 2023VOSSIUS & PARTNER PATENTANWALTE RECHTSANWALTE MBBADMISSIBLE
GLEISS GROSSE SCHRELL UND PARTNER MBBJun 5, 2023SCHRELLADMISSIBLE

Patent Citations (11) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication NumberPublication Link
INTERNATIONAL-SEARCH-REPORTEP2468856
INTERNATIONAL-SEARCH-REPORTUS2011243915
INTERNATIONAL-SEARCH-REPORTUS2012189606
INTERNATIONAL-SEARCH-REPORTUS2013052182
INTERNATIONAL-SEARCH-REPORTWO2011023702
OPPOSITIONEP2468856
OPPOSITIONUS2010254950
OPPOSITIONWO2010141135
OPPOSITIONWO2015005787
OPPOSITIONWO2015155244
OTHERUS2010254950

Non-Patent Literature (NPL) Citations (23) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference TextLink
OPPOSITION- Anonymous, "Persister cells", Wikipedia, (20240703), Wikipedia, URL: https://en.wikipedia.org/w/index.php?title=Persister cells&oldid=1232325763, XP093211526-
OPPOSITION- BORYSOWSKI J, WEBER-DABROWSKA B, GORSKI A, "Bacteriophage endolysins as a novel class of antibacterial agents", Experimental Biology and Medicine, Sage Publications Ltd., GB, GB , (20060401), vol. 231, no. 4, ISSN 1535-3702, pages 366 - 377, XP002513942-
OPPOSITION- Saß Peter, "Antibacterial treatment of Staphylococcus aureus: Response and resistance to the lantibiotic mersacidin and evaluation of endolysins as a biofilm treatment strategy", Dissertation, (20090101), pages 1 - 133, XP093193961-
OPPOSITION- Vincent A. Fischetti, "Bacteriophage endolysins: A novel anti-infective to control Gram-positive pathogens", International Journal of Medical Microbiology, (2010), vol. 300, XP027207245-
OPPOSITION- Daniel C. Nelson, Mathias Schmelcher, Lorena Rodriguez-Rubio, Jochen Klumpp, David G. Pritchard, Shengli Dong, David M. Donovan, "Endolysins as Antimicrobials", Daniel C. Nelson, Mathias Schmelcher, Lorena Rodriguez-Rubio, Jochen Klumpp, David G. Pritchard, Shengli Dong, David M. Donovan, Gerard Meurant, Karl Maramorosch, Frederick A. Murphy, and Aaron J. Shatkin, Advances in Virus Research, US , Academic Press , (20120101), vol. 83, pages 299 - 365, doi:10.1016/B978-0-12-394438-2.00007-4, ISSN 0065-3527, XP055220045
OPPOSITION- Yves Briers et al., "The high-affinity peptidoglycan binding domain of Pseudomonas phage endolysin KZ144", Biochemical and Biophysical Research Communications, (2009), vol. 383, doi:10.1016/j.bbrc.2009.03.161, XP026057388
OPPOSITION- Loessner, M.J., "Bacteriophage endolysins - current state of research and applications", CURRENT OPINION IN MICROBIOLOGY, CURRENT BIOLOGY LTD, GB, GB , (20050801), vol. 8, no. 4, doi:10.1016/j.mib.2005.06.002, ISSN 1369-5274, pages 480 - 487, XP004989436
OPPOSITION- Fischetti, V.A., "Bacteriophage lysins as effective antibacterials", CURRENT OPINION IN MICROBIOLOGY, CURRENT BIOLOGY LTD, GB, GB , (20081001), vol. 11, no. 5, doi:10.1016/j.mib.2008.09.012, ISSN 1369-5274, pages 393 - 400, XP025744750
OPPOSITION- Kim Lewis null, "Persister cells, dormancy and infectious disease", Nat Rev Micro, (2007), vol. 5, doi:10.1038/nrmicro1557, XP009164216
OPPOSITION- Stewart, P.S., "Mechanisms of antibiotic resistance in bacterial biofilms", INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY, URBAN UND FISCHER, DE, DE , (20020101), vol. 292, no. 2, doi:10.1078/1438-4221-00196, ISSN 1438-4221, pages 107 - 113, XP004960049
OPPOSITION- Vesga O., Groeschel M. C., Otten M. F., Brar D. W., Vann J. M., Proctor R. A., "Staphylococcus aureus Small Colony Variants Are Induced by the Endothelial Cell Intracellular Milieu", Journal of Infectious Diseases, University of Chicago Press, US, US , (19960301), vol. 173, no. 3, doi:10.1093/infdis/173.3.739, ISSN 0022-1899, pages 739 - 742, XP093112339
OPPOSITION- Y. Briers et al., "Use of bacteriophage endolysin EL188 and outer membrane permeabilizers against Pseudomonas aeruginosa", Journal of Applied Microbiology, (2011), vol. 110, doi:10.1111/j.1365-2672.2010.04931.x, XP055330833
OPPOSITION- C. C. Teneback, T. C. Scanlon, M. J. Wargo, J. L. Bement, K. E. Griswold, L. W. Leclair, "Bioengineered Lysozyme Reduces Bacterial Burden and Inflammation in a Murine Model of Mucoid Pseudomonas aeruginosa Lung Infection", Antimicrobial agents and chemotherapy, American Society for Microbiology., (20131101), vol. 57, no. 11, doi:10.1128/AAC.00500-13, ISSN 00664804, pages 5559 - 5564, XP055123713
OPPOSITION- Y. Briers, M. Walmagh, B. Grymonprez, M. Biebl, J.-P. Pirnay, V. Defraine, J. Michiels, W. Cenens, A. Aertsen, S. Miller, R. Lavigne, "Art-175 Is a Highly Efficient Antibacterial against Multidrug-Resistant Strains and Persisters of Pseudomonas aeruginosa", Antimicrobial agents and chemotherapy, American Society for Microbiology., (20140701), vol. 58, no. 7, doi:10.1128/AAC.02668-14, ISSN 00664804, pages 3774 - 3784, XP055194736
OPPOSITION- Yves Briers et al., "Art-175 Is a Highly Efficient Antibacterial against Multidrug -Resistant Strains and Persisters of Pseudomonas aeruginosa", Antimicrobial Agents and Chemotherapy, (2014), vol. 58, doi:10.1128/AAC.02668-14, XP055194736
OPPOSITION- SASS PETER, BIERBAUM G, "Lytic activity of recombinant bacteriophage phi11 and phi12 endolysins on whole cells and biofilms of Staphylococcus aureus.", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, American Society for Microbiology, US, US , (20070101), vol. 73, no. 1, doi:10.1128/AEM.01616-06, ISSN 0099-2240, pages 347 - 352, XP002499603
OPPOSITION- Quickel Kenneth E., Selden Richard, Caldwell Jacques R., Nora Nedo F., Schaffner William, "Efficacy and Safety of Topical Lysostaphin Treatment of Persistent Nasal Carriage of Staphylococcus aureus", APPLIED MICROBIOLOGY, American Society for Microbiology, US, US , (19710901), vol. 22, no. 3, doi:10.1128/am.22.3.446-450.1971, ISSN 0003-6919, pages 446 - 450, XP093112338
OPPOSITION- Y. Briers, M. Walmagh, V. Van Puyenbroeck, A. Cornelissen, W. Cenens, A. Aertsen, H. Oliveira, J. Azeredo, G. Verween, J.-P. Pirnay, S. Miller, G. Volckaert, R. Lavigne, "Engineered Endolysin-Based "Artilysins" To Combat Multidrug-Resistant Gram-Negative Pathogens", mBio, American Society for Microbiology, US, US , (20140701), vol. 5, no. 4, doi:10.1128/mBio.01379-14, ISSN 2150-7511, page e01379, XP055307172
OPPOSITION- Hurley Matthew N., Cámara Miguel, Smyth Alan R., "Novel approaches to the treatment of Pseudomonas aeruginosa infections in cystic fibrosis", EUROPEAN RESPIRATORY JOURNAL, European Respiratory Society, GB, GB , (20121001), vol. 40, no. 4, doi:10.1183/09031936.00042012, ISSN 0903-1936, pages 1014 - 1023, XP093122457
OPPOSITION- Maarten Walmagh et al., "Characterization of Modular Bacteriophage Endolysins from Myoviridae Phages OBP, 201Phi2-1 and PVP-SE1", PLoS ONE, (2012), vol. 7, doi:10.1371/journal.pone.0036991, XP055041652
OPPOSITION- Gutiérrez Diana, Ruas-Madiedo Patricia, Martínez Beatriz, Rodríguez Ana, García Pilar, "Effective Removal of Staphylococcal Biofilms by the Endolysin LysH5", PLOS ONE, Public Library of Science, US, US , vol. 9, no. 9, doi:10.1371/journal.pone.0107307, ISSN 1932-6203, page e107307, XP093112345
OPPOSITION- Drulis-Kawa Zuzanna, Majkowska-Skrobek Grazyna, Maciejewska Barbara, Delattre Anne-Sophie, Lavigne Rob, "Learning from Bacteriophages - Advantages and Limitations of Phage and Phage-Encoded Protein Applications", CURRENT PROTEIN AND PEPTIDE SCIENCE, BENTHAM SCIENCE PULBISHERS, NL, NL , (20121201), vol. 13, no. 8, doi:10.2174/138920312804871193, ISSN 1389-2037, pages 699 - 722, XP093232730
OPPOSITION- Mathias Schmelcher, David M Donovan, Martin J Loessner, "Bacteriophage endolysins as novel antimicrobials", Future Microbiology, (20121001), vol. 7, no. 10, doi:10.2217/fmb.12.97, ISSN 17460913, pages 1147 - 1171, XP055180173

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