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The patent EP3131582 was granted to Vertex Pharmaceuticals Incorporated on May 23, 2018. The application was filed on Apr 14, 2015 under application number EP15721912A. The patent is currently recorded with a legal status of "Granted And Under Opposition".
Pharmaceutical compositions for treating CFTR-mediated diseases with improved properties. The compositions contain a mixture of therapeutic agents, including a CFTR corrector and a CFTR potentiator, in spray dried dispersion form. The dispersions are substantially free of polymer. The spray drying process helps to improve the properties of the therapeutic agents when combined in this way. The compositions can be used to treat cystic fibrosis by providing enhanced CFTR function.

Patent oppositions filed by competitors challenge the validity of a granted patent. These oppositions are typically based on claims of prior art, lack of novelty, or non-obviousness. They are a key part of the process for determining a patent's strength and enforceability.
| Company | Opposition Date | Representative | Opposition Status |
|---|---|---|---|
| GENERICS UK | Feb 22, 2019 | TER MEER STEINMEISTER & PARTNER | ADMISSIBLE |
Patent citations refer to prior patents cited during different phases such as opposition or international search.
| Citation Phase | Publication Number |
|---|---|
| DESCRIPTION | US2003144257 |
| DESCRIPTION | US2004006237 |
| DESCRIPTION | US2004105820 |
| DESCRIPTION | US2005164973 |
| DESCRIPTION | US2006035943 |
| DESCRIPTION | US2006148863 |
| DESCRIPTION | US2006148864 |
| DESCRIPTION | US2009131492 |
| DESCRIPTION | US2013316981 |
| DESCRIPTION | US6992096 |
| DESCRIPTION | US7202262 |
| DESCRIPTION | US8247436 |
| DESCRIPTION | WO0152902 |
| DESCRIPTION | WO2004028480 |
| DESCRIPTION | WO2004080972 |
| DESCRIPTION | WO2004091502 |
| DESCRIPTION | WO2004110352 |
| DESCRIPTION | WO2004111014 |
| DESCRIPTION | WO2005035514 |
| DESCRIPTION | WO2005049018 |
| DESCRIPTION | WO2005094374 |
| DESCRIPTION | WO2005120497 |
| DESCRIPTION | WO2006044456 |
| DESCRIPTION | WO2006044502 |
| DESCRIPTION | WO2006044503 |
| DESCRIPTION | WO2006044505 |
| DESCRIPTION | WO2006044682 |
| DESCRIPTION | WO2006099256 |
| DESCRIPTION | WO2006101740 |
| DESCRIPTION | WO2006110483 |
| DESCRIPTION | WO2006127588 |
| DESCRIPTION | WO2007044560 |
| DESCRIPTION | WO2011113894 |
| INTERNATIONAL-SEARCH-REPORT | WO2011119984 |
| INTERNATIONAL-SEARCH-REPORT | WO2013185112 |
| INTERNATIONAL-SEARCH-REPORT | WO2014014841 |
| OPPOSITION | WO2011119984 |
| OPPOSITION | WO2013185112 |
| OPPOSITION | WO2014014841 |
The dossier documents provide a comprehensive record of the patent's prosecution history - including filings, correspondence, and decisions made by patent offices - and are crucial for understanding the patent's legal journey and any challenges it may have faced during examination.
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Decision to grant a European patent
Search/Exam
Mar 6, 2018
(Electronic) Receipt
Search/Exam
Mar 6, 2018
Filing of the translations of the claims
Search/Exam
Mar 6, 2018
French translation of claims
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Mar 6, 2018
German translation of the claims
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Mar 6, 2018
Letter accompanying subsequently filed items
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Dec 15, 2017
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Communication to designated inventor
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(Electronic) Receipt
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Dec 6, 2017
Letter accompanying subsequently filed items
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Dec 6, 2017
Letter concerning the inventor
Search/Exam
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Intention to grant (signatures)
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Oct 27, 2017
Text intended for grant (clean copy)
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Sep 26, 2017
Examination started
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Jun 5, 2017
(Electronic) Receipt
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Jun 5, 2017
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Amendments received before examination
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Jun 5, 2017
Letter accompanying subsequently filed items
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May 17, 2017
Refund of fees
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Letter which had not been notified
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Letter which had not been notified
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(Electronic) Receipt
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Dec 16, 2016
Letter accompanying subsequently filed items
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Letter which had not been notified
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Communication to designated inventor
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Communication to designated inventor
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Communication to designated inventor
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Communication to designated inventor
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Communication to designated inventor
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Communication to designated inventor
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Communication to designated inventor
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Communication to designated inventor
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Communication to designated inventor
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Communication to designated inventor
Search/Exam
Nov 9, 2016
(Electronic) Receipt
Search/Exam
Nov 9, 2016
Request for entry into the European phase
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Oct 31, 2016
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Notification of the recording of a change
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Aug 26, 2016
Information on entry into European phase
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Copy of the international search report
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Oct 22, 2015
Published international application - A1
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Abstract
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Annex
PCTISA
May 4, 2015
Claims
PCTISA
May 4, 2015
Description
PCTISA
May 4, 2015
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PCTISA
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