Mnd Promoter Chimeric Antigen Receptors - EP3134432

The patent EP3134432 was granted to Bluebird BIO on Dec 25, 2019. The application was originally filed on Apr 24, 2015 under application number EP15782739A. The patent is currently recorded with a legal status of "Revoked".

EP3134432

BLUEBIRD BIO
Application Number
EP15782739A
Filing Date
Apr 24, 2015
Status
Revoked
Jul 2, 2025
Grant Date
Dec 25, 2019
External Links
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PATENT BOUTIQUESep 25, 2020BOULT WADE TENNANTADMISSIBLE

Patent Citations (8) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication NumberPublication Link
INTERNATIONAL-SEARCH-REPORTUS2013004471
INTERNATIONAL-SEARCH-REPORTWO2014055771
OPPOSITIONAU2013204923
OPPOSITIONWO2012079000
OPPOSITIONWO2014031687
OTHEREP3134432
SEARCHAU2013204923
SEARCHWO2014031687

Non-Patent Literature (NPL) Citations (14) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference TextLink
OPPOSITION- G J Avilés Mendoza, N E Seidel, M Otsu, S M Anderson, K Simon-Stoos, A Herrera, S Hoogstraten-Miller, H L Malech, F Candotti, J M Puck, D M Bodine, "Comparison of Five Retrovirus Vectors Containing the Human IL-2 Receptor gamma ChainGene for Their Ability to Restore T and B Lymphocytes in the X-Linked Severe Combined Immunodeficiency Mouse Model", Molecular Therapy, (20010400), vol. 3, no. 4, pages 565 - 573, XP055739336-
OPPOSITION- Sarah M. Larson, MD, AndyTu, Shanta Senadheera, Michelle Ho, BS, Donald B. Kohn, MD, Satire deOliveira, MD, "Anti-CD19 Chimeric Antigen Receptor Controlled By The Suicide Gene HSVsr39TK ln Hematopoietic Stem Cells For Immunotherapy Of B-Lineage Malignancies", Blood, (20131115), vol. 122, no. 21, page 1659-
OPPOSITION- Lin Liu; Meili Sun; Zhehai Wang, "Adoptive T-cell therapy of B-cell malignancies: Conventional and physiological chimeric antigen receptors", Cancer Letters, (20120000), vol. 316, no. 1, pages 1 - 5, XP028434062
OPPOSITION- Mingjie Li, Husic Nada, Lin Ying, Christensen Heather, Malik Ibrahim, Mciver Sally, Daniels Christine M. Lapash, Harris David A., Kotzbauer Paul T., Goldberg Mark P., Snider B. Joy, "Optimal promoter usage for lentiviral vector-mediated transduction of cultured central nervous system cells /NIH Author Manuscript/", J. Neurosci. Methods, (20100000), vol. 189, no. 1, pages 56 - 64, XP055739348
OPPOSITION- Blythe D Sather; Byoung Y Ryu; Brigid V Stirling; Mikhail Garibov; Hannah M Kerns; Stéphanie Humblet-Baron; Alexander Astrakhan; David J Rawlings, "Development of B-lineage Predominant Lentiviral Vectors for Use in Genetic Therapies for B Cell Disorders", Molecular Therapy, (20110000), vol. 19, no. 3, pages 515 - 525, XP055416833
OPPOSITION- Francesca Giannoni, Cinnamon L Hardee, Jennifer Wherley, Eric Gschweng, Shantha Senadheera, Michael L Kaufman, Rebecca Chan, Ingrid Bahner, Vivian Gersuk, Xiaoyan Wang, David Gjertson, David Baltimore, Owen N Witte, James S Economou, Antoni Ribas, Donald B Kohn, "Allelic Exclusion and Peripheral Reconstitution by TCR Transgenic T Cells Arising From Transduced Human Hematopoietic Stem/Progenitor Cells", Molecular Therapy, (20130000), vol. 21, no. 5, pages 1044 - 1054, XP055739372
OPPOSITION- Satiro Nakamura De Oliveira; Christine Ryan; Francesca Giannoni; Cinnamon L Hardee; Irena Tremcinska; Behrod Katebian; Jennifer Wherley; Arineh Sahaghian; Andy Tu; Tristan Grogan; David Elashoff; Laurence J N Cooper; Roger P Hollis; Donald B Kohn, "Modification of Hematopoietic Stem/Progenitor Cells with CD19-Specific Chimeric Antigen Receptors as a Novel Approach for Cancer Immunotherapy", Human Gene Therapy, (20130000), vol. 24, no. 10, pages 824 - 839, XP055244062
OPPOSITION- Rachel M. Koldej, Gael Carney, Matthew M. Wielgosz, Sheng Zhou, Jun Zhan, Brian P. Sorrentino, And Arthur W. Nienhuis, "Comparison of Insulators and Promoters for Expression of the Wiskott-Aldrich Syndrome Protein Using Lentiviral Vectors", Human Gene Therapy Clinical Development, (20130000), vol. 24, no. 2, pages 77 - 85, XP055739355
OPPOSITION- Alexander Astrakhan, Sather Blythe D, Ryu Byoung Y, Khim Socheath, Singh Swati, Humblet-Baron Stephanie, Ochs Hans D, Miao Carol H, Rawlings David J, "Ubiquitous high-level gene expression in hematopoietic lineages provides effective lentiviral gene therapy of murine Wiskott-Aldrich syndrome", Blood, (20120000), vol. 119, no. 19, pages 4395 - 4407, XP055739380
OPPOSITION- Ethan Q Han; Xiu-ling Li; Chun-rong Wang; Tian-fang Li; Shuang-yin Han, "Chimeric antigen receptor-engineered T cells for cancer immunotherapy: progress and challenges", Journal of Hematology & Oncology, (20130000), vol. 6, no. 1, page 47, XP021155859
SEARCH- LIN LIU ET AL, "Adoptive T-cell therapy of B-cell malignancies: Conventional and physiological chimeric antigen receptors", CANCER LETTERS, NEW YORK, NY, US, vol. 316, no. 1, doi:10.1016/J.CANLET.2011.10.027, ISSN 0304-3835, (20111019), pages 1 - 5, (20111029), XP028434062 [Y] 1-16 * the whole document *
SEARCH- W K CHAN ET AL, "Chimeric antigen receptor-redirected CD45RA-negative T cells have potent antileukemia and pathogen memory response without graft-versus-host activity", LEUKEMIA., US, (20150201), vol. 29, no. 2, doi:10.1038/leu.2014.174, ISSN 0887-6924, pages 387 - 395, XP055403336 [XP] 1-14 * the whole document *
SEARCH- BLYTHE D SATHER ET AL, "Development of B-lineage Predominant Lentiviral Vectors for Use in Genetic Therapies for B Cell Disorders", MOLECULAR THERAPY, US, (20110301), vol. 19, no. 3, doi:10.1038/mt.2010.259, ISSN 1525-0016, pages 515 - 525, XP055416833 [Y] 1-16 * the whole document *
SEARCH- SATIRO NAKAMURA DE OLIVEIRA ET AL, "Modification of Hematopoietic Stem/Progenitor Cells with CD19-Specific Chimeric Antigen Receptors as a Novel Approach for Cancer Immunotherapy", HUMAN GENE THERAPY, US, (20131001), vol. 24, no. 10, doi:10.1089/hum.2012.202, ISSN 1043-0342, pages 824 - 839, XP055244062 [X] 1-5,7,8,11-13 * figure 1 * [Y] 6,9,10,14,15

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