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Method For The Expression Of Polypeptides Using Modified Nucleic Acids - EP3138917

The patent EP3138917 was granted to F Hoffmann LA Roche on Oct 23, 2024. The application was originally filed on Apr 15, 2013 under application number EP16188552A. The patent is currently recorded with a legal status of "Patent Maintained As Amended".

EP3138917

F HOFFMANN LA ROCHE
Application Number
EP16188552A
Filing Date
Apr 15, 2013
Status
Patent Maintained As Amended
Sep 19, 2024
Grant Date
Oct 23, 2024
External Links
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SCORPIOMay 21, 2020SAGITTARIUSADMISSIBLE

Patent Citations (3) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication Number
OPPOSITIONUS7479543
OPPOSITIONUS8128938
OPPOSITIONWO2013156443

Non-Patent Literature (NPL) Citations (15) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference Text
OPPOSITION- A Hénaut, Danchin A, "Analysis and Predictions from Escherichia coli Sequences, or E. coli In Silico", ASM Press, (19960101), URL: https://www.asmscience.org/files/Chapter_114_Analysis_and_Predictions_from_Escherichia_coli_Sequences_or_E._coli_In_Silico.pdf, (20200828), XP055725848
OPPOSITION- Anonymous, "Technologies for Monoclonal Antibody Production", GIBCO- Invitrogen Brochure, Thermo Fisher Scientifique, (20010101), pages 1 - 7, GIBCO- Invitrogen Brochure, URL: https://assets.thermofisher.com/TFS-Assets/LSG/brochures/B_08A00_745_monoantibdy_bro.pdf, XP055626357
OPPOSITION- David Raab, Marcus Graf, Frank Notka, Thomas Schodl, Ralf Wagner, "The GeneOptimizer Algorithm: using a sliding window approach to cope with the vast sequence space in multiparameter DNA sequence optimization", Systems and Synthetic Biology, Springer Netherlands, (20100901), vol. 4, no. 3, doi:10.1007/s11693-010-9062-3, ISSN 18725325, pages 215 - 225, XP055065511
OPPOSITION- Li, A. Kato, Z. Ohnishi, H. Hashimoto, K. Matsukuma, E. Omoya, K. Yamamoto, Y. Kondo, N., "Optimized gene synthesis and high expression of human interleukin-18", PROTEIN EXPRESSION AND PURIFICATION., ACADEMIC PRESS, SAN DIEGO, CA., SAN DIEGO, CA., (20031101), vol. 32, no. 1, doi:10.1016/j.pep.2003.08.003, ISSN 1046-5928, pages 110 - 118, XP004469392
OPPOSITION- Gustafsson, C. Govindarajan, S. Minshull, J., "Codon bias and heterologous protein expression", TRENDS IN BIOTECHNOLOGY., ELSEVIER PUBLICATIONS, CAMBRIDGE., GB, GB, (20040701), vol. 22, no. 7, doi:10.1016/j.tibtech.2004.04.006, ISSN 0167-7799, pages 346 - 353, XP004520507
OPPOSITION- Gary Walsh, "Biopharmaceutical benchmarks 2006", Nature Biotechnology, Gale Group Inc., New York, us, us, (20060701), vol. 24, no. 7, doi:10.1038/nbt0706-769, ISSN 1087-0156, pages 769 - 776, XP055725857
OPPOSITION- Plotkin Joshua B.; Kudla Grzegorz, "Synonymous but not the same: the causes and consequences of codon bias", NATURE REVIEWS GENETICS, Nature Publishing Group, GB, GB, (20101123), vol. 12, no. 1, doi:10.1038/nrg2899, ISSN 1471-0056, pages 32 - 42, XP037115078
OPPOSITION- Graziano Pesole, Attimonelli Marcella, Liuni Sabino, "A backtranslation method based on codon usage strategy", Nucleic Acids Research, Information Retrieval Ltd., (19880311), vol. 16, no. 5, doi:10.1093/nar/16.5.1715, ISSN 0305-1048, pages 1715 - 1728, XP055725859
OPPOSITION- R Grantham, Gautier C, Gouy M, Mercier R, Pavé A, "Codon catalog usage and the genome hypothesis", Nucleic Acids Research, (19800111), vol. 8, no. 1, pages r49 - r62, XP055725317
OPPOSITION- Villalobos Alan; Ness Jon E; Gustafsson Claes; Minshull Jeremy; Govindarajan Sridhar, "Gene Designer: a synthetic biology tool for constructing artificial DNA segments", BMC BIOINFORMATICS, BIOMED CENTRAL, LONDON, GB, GB, (20060606), vol. 7, no. 1, doi:10.1186/1471-2105-7-285, ISSN 1471-2105, pages 1 - 8, XP021013796
OPPOSITION- Stephan Fath, Et Al., "Multiparameter RNA and Codon Optimization: A Standardized Tool to Assess and Enhance Autologous Mammalian Gene Expression", PLoS ONE, (20110303), vol. 6, no. 3, doi:10.1371/journal.pone.0017596, pages 1 - 14, XP055531212
SEARCH- CANNAROZZI GINA ET AL, "A Role for Codon Order in Translation Dynamics", CELL, (20100416), vol. 141, no. 4, ISSN 0092-8674, pages 355 - 367, XP002676934 [A] 1-12 * the whole document *
SEARCH- GUSTAFSSON CLAES ET AL, "Codon bias and heterologous protein expression", TRENDS IN BIOTECHNOLOGY, (200407), vol. 22, no. 7, ISSN 0167-7799, pages 346 - 353, XP002676933 [A] 1-12 * the whole document *
SEARCH- PLOTKIN JOSHUA B ET AL, "Synonymous but not the same: the causes and consequences of codon bias", NATURE REVIEWS GENETICS, (201101), vol. 12, no. 1, ISSN 1471-0056, pages 32 - 42, XP002676932 [A] 1-12 * the whole document *
SEARCH- WATKINS NORMAN E JR ET AL, "Nearest-neighbor thermodynamics of deoxyinosine pairs in DNA duplexes", NUCLEIC ACIDS RESEARCH, (2005), vol. 33, no. 19, ISSN 0305-1048, pages 6258 - 6267, XP002676931 [A] 1-12 * table 6 *

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