Affinity Chromatography Media For Removal Of Anti-A And/Or Anti-B Antibodies - EP3141558

The patent EP3141558 was granted to Merck Patent on Feb 16, 2022. The application was originally filed on Sep 8, 2016 under application number EP16187838A. The patent is currently recorded with a legal status of "Patent Maintained As Amended".

EP3141558

MERCK PATENT
Application Number
EP16187838A
Filing Date
Sep 8, 2016
Status
Patent Maintained As Amended
Jan 14, 2022
Grant Date
Feb 16, 2022
External Links
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KIPAFeb 24, 2020KIPAADMISSIBLE
CABINET LAURENT & CHARRASFeb 20, 2020-ADMISSIBLE

Patent Citations (13) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication Number
DESCRIPTIONWO2015001277
OPPOSITIONFR1554084
OPPOSITIONUS2015133636
OPPOSITIONUS8153382
OPPOSITIONWO2007077365
OPPOSITIONWO2013062479
OPPOSITIONWO2015001277
OPPOSITIONWO2016177966
OPPOSITIONWO9513861
SEARCHFR3008097
SEARCHFR3008098
SEARCHWO0127623
SEARCHWO2013062479

Non-Patent Literature (NPL) Citations (48) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference Text
DESCRIPTION- CHEMICAL SOC. REV., (1978), vol. 7, pages 423 - 452
DESCRIPTION- CHRISTENSSON ET AL., TRANSFUSION, (1996), vol. 36, pages 50 - 505
DESCRIPTION- CHRISTENSSON, M., I, TRANSFUSION, (1996), vol. 36, pages 500 - 505
DESCRIPTION- REV. FR. TRANSFUS. IMMUNOHEMATOL., (1981), vol. 24, no. 3, pages 281 - 287
DESCRIPTION- THORPE SJ ET AL., VOX SANGUINIS, (2009), vol. 97, pages 160 - 168
DESCRIPTION- TRANSFUSION, (1972), vol. 12, pages 98 - 102
DESCRIPTION- VOX SANG., (1967), vol. 12, pages 75 - 77
DESCRIPTION- VOX SANG., (1991), vol. 61, pages 53 - 58
OPPOSITION- anonymous, "ProSepĀ® Ultra Plus Chromatography media", EMD MILLIPORE - Data sheet, (20140000), URL: https://www.merckmillipore.com/NL/en/product/ProSep-Ultra-Plus-Chromatography-Media,MM_NF-C7842#documentation
OPPOSITION- anonymous, "ProSepĀ® Ultra Plus Chromatography media", EMD MILLIPORE - Data sheet, (20140000), URL: https://www.merckmillipore.com/NL/en/product/ProSep-Ultra-Plus-Chromatography-Media,MM_NF-C7842#documentation, XP055695847
OPPOSITION- ANSPACH, BIRGER F. et al., "Purification of recombinant human basic fibroblast growth factor: stability of selective sorbents under cleaning in place conditions", Journal of Chromatography A, (19950000), vol. 711, doi:10.1016/0021-9673(95)00102-S, pages 129 - 139
OPPOSITION- BENSINGER, WILLIAM I. et al., "Immunoabsorption for removal of A and B blood-group antibodies", The New England Journal of Medicine, (19810115), vol. 304, no. 3, pages 160 - 162
OPPOSITION- "Biochromatography Portfolio Guide - Bulk Resin, Membranes and Prepacked Columns", (20191000), XP055717715
OPPOSITION- BLOMBERG et al., "Improved removal of anti-A and anti-B antibodies from plasma using blood-group-active haptens", Vox Sang, (19930000), vol. 65, pages 126 - 135
OPPOSITION- BLOMBERG et al., "Improved removal of anti-A and anti-B antibodies from plasma using blood-group-active haptens", Vox Sang, (19930000), vol. 65, pages 126 - 135, XP002941315
OPPOSITION- BLOMBERG L. et al., "Improved Removal of Anti-A and Anti-B from Plasma Using Blood-Group-Active Haptens", Vox Sang, (19930000), vol. 65, pages 126 - 135, XP002941315
OPPOSITION- FIDDLER et al., "Immobilization of proteins on aldehyde-activated polyacrylamide supports", Analytical Biochemistry, (19780000), vol. 86, doi:10.1016/0003-2697(78)90799-6, pages 716 - 724
OPPOSITION- Gary R. GRAY, "Affinity chromatography", Anal. Chem., (19800400), vol. 52, no. 5, pages 9R - 15R
OPPOSITION- Gary R. GRAY, "Affinity chromatography", Anal. Chem., (19800400), vol. 52, no. 5, pages 9R - 15R, XP001270262
OPPOSITION- HELLBERG A. et al, "Chemical and functional stability of a new protein A media with high dynamic binding capacity based on novel, highly rigid agarose beads", Amersham Biosciences, Sweden, (20000000), pages 1 - 4
OPPOSITION- HELLBERG A. et al, "Chemical and functional stability of a new protein A media with high dynamic binding capacity based on novel, highly rigid agarose beads", Amersham Biosciences, Sweden, (20000000), pages 1 - 4, XP055695853
OPPOSITION- H. Solmaz et al, "Composite cryogel with immobilized concanavalin A for affinity chromatography of glycoproteins", Journal of Separation Science, (20121101), vol. 35, no. 21, ISSN 1615-9306, pages 2978 - 2985
OPPOSITION- "Immobilized Oligosaccharides", IsoSep, IsoSep Specialists in Carbohydrates and Glycoconjugates Catalog 2002/2003, (2002), page 26, XP055695860
OPPOSITION- "Immobilized Oligosaccharides", IsoSep Specialists in Carbohydrates and Glycoconjugates Catalog 2002/2003, (20020000), page 26, XP055695860
OPPOSITION- IVANOV, ALEXANDER E. et al., "Favourable Biospecific Reactivity of Blood Group B Antigenic Trisaccharide Chemically Attached to Poly-N-(2-hydroxyethyl)acrylamide-coated Porous Glass", Biomedical Chromatography, (19920000), vol. 6, pages 39 - 42, XP055695837
OPPOSITION- IVANOV et al., "Favourable biospecific reactivity of blood group B antigenic trisaccharide chemically attached to poly-N-(hydroxyethyl)acrylamide-coated porous glass", BIOMEDICAL CHROMATOGRAPH, (19920430), vol. 6, no. 1, pages 39 - 42
OPPOSITION- IVANOV et al., "Favourable biospecific reactivity of blood group B antigenic trisaccharide chemically attached to poly-N-(hydroxyethyl)acrylamide-coated porous glass", BIOMEDICAL CHROMATOGRAPH, (19920430), vol. 6, no. 1, pages 39 - 42, XP055695837
OPPOSITION- IVANOV et al., "Inorganic supports coated with N-substituted polyacrylamides: application to biospecific chromatography of proteins", Biomedical Chromatography, (19910300), vol. 5, no. 2, pages 90 - 93
OPPOSITION- KANAMORI et al., "Preparation of high-capacity affinity adsorbents using formyl carriers and their use for low- and high-performance liquid affinity chromatography of trypsin-family proteases", Journal of Chromatography, (19860000), vol. 363, pages 231 - 242
OPPOSITION- MATSUMOTO et al., "Derivatization of epoxy-activated agarose with various carbohydrates for the preparation of stable and high-capacity affinity adsorbents: their use for affinity chromatography of carbohydrate-binding proteins", Analytical Biochemistry, (19810000), vol. 116, doi:10.1016/0003-2697(81)90329-8, pages 103 - 110
OPPOSITION- MAZID, ABDUL M. et al., "An Improved Affinity Support and Immunoadsorbent with a Synthetic Blood Group Oligosaccharide and Polymer Coating for Hemoperfusion", Journal of Applied Biomaterials, (19920000), vol. 3, doi:10.1002/jab.770030103, pages 9 - 15
OPPOSITION- MAZID et al., "Immunoadsorbents with synthetic oligosaccharide hapten representing blood group A substances", Bioconjugate Chem., (19910100), vol. 2, no. 1, pages 32 - 37
OPPOSITION- M. Urmann, "Cation-exchange chromatography of monoclonal antibodies Characterization of a novel stationary phase designed for production-scale purification", MABS, (20100801), vol. 2, no. 4, pages 395 - 404
OPPOSITION- PRITCHARD, DAVID G. et al., "Murine Monoclonal Antibodies to Type lb Polysaccharide of Group B Streptococci Bind to Human Milk Oligosaccharides", INFECTION AND IMMUNITY, (19920400), vol. 60, pages 1598 - 1602
OPPOSITION- PRITCHARD, DAVID G. et al., "Murine Monoclonal Antibodies to Type lb Polysaccharide of Group B Streptococci Bind to Human Milk Oligosaccharides", INFECTION AND IMMUNITY, (19920400), vol. 60, pages 1598 - 1602, XP055717706
OPPOSITION- IVANOV et al., "Inorganic supports coated with N-substituted polyacrylamides: application to biospecific chromatography of proteins", Biomedical Chromatography, (19910300), vol. 5, no. 2, pages 90 - 93, XP055695842
OPPOSITION- MAZID, ABDUL M. et al., "An Improved Affinity Support and Immunoadsorbent with a Synthetic Blood Group Oligosaccharide and Polymer Coating for Hemoperfusion", Journal of Applied Biomaterials, (19920000), vol. 3, doi:10.1002/jab.770030103, pages 9 - 15, XP008069266
OPPOSITION- OSTERWALDER, B. et al., "Immunoadsorption for Removal of Anti-A and Anti-B Blood Group Antibodies in ABO- Incompatible Bone Marrow Transplantation", Blut, (19860000), vol. 53, pages 379 - 390, XP055717708
OPPOSITION- FIDDLER et al., "Immobilization of proteins on aldehyde-activated polyacrylamide supports", Analytical Biochemistry, (19780000), vol. 86, doi:10.1016/0003-2697(78)90799-6, pages 716 - 724, XP024820882
OPPOSITION- MATSUMOTO et al., "Derivatization of epoxy-activated agarose with various carbohydrates for the preparation of stable and high-capacity affinity adsorbents: their use for affinity chromatography of carbohydrate-binding proteins", Analytical Biochemistry, (19810000), vol. 116, doi:10.1016/0003-2697(81)90329-8, pages 103 - 110, XP024826341
OPPOSITION- ANSPACH, BIRGER F. et al., "Purification of recombinant human basic fibroblast growth factor: stability of selective sorbents under cleaning in place conditions", Journal of Chromatography A, (19950000), vol. 711, doi:10.1016/0021-9673(95)00102-S, pages 129 - 139, XP004038958
OPPOSITION- ROGERS et al., "Development of a rapid sanitization solution for silica-based protein A affinity adsorbents", Journal of Chromatography A, (20090000), vol. 1216, pages 4589 - 4590, XP026084384
OPPOSITION- ROGERS et al., "Development of a rapid sanitization solution for silica- based protein A affinity adsorbents", Journal of Chromatography A, (20090328), vol. 1216, no. 21, pages 4589 - 4590, XP026460269
OPPOSITION- KANAMORI et al., "Preparation of high-capacity affinity adsorbents using formyl carriers and their use for low- and high-performance liquid affinity chromatography of trypsin-family proteases", Journal of Chromatography, (19860000), vol. 363, doi:10.1016/S0021-9673(01)83742-0, pages 231 - 242, XP026479926
OPPOSITION- MAZID, ABDUL M. et al., "Immunoadsorbents with Synthetic Oligosaccharide Hapten Representing Blood Group A Substances", Bioconjugate Chem, (19910000), vol. 2, pages 32 - 37, XP055695830
OPPOSITION- MAZID et al., "Immunoadsorbents with synthetic oligosaccharide hapten representing blood group A substances", Bioconjugate Chem., (19910100), vol. 2, no. 1, pages 32 - 37, XP055695830
OPPOSITION- BENSINGER, WILLIAM I. et al., "Immunoabsorption for removal of A and B blood-group antibodies", The New England Journal of Medicine, (19810115), vol. 304, no. 3, pages 160 - 162, XP008160047
SEARCH- ROGERS M ET AL, "Development of a rapid sanitization solution for silica-based protein A affinity adsorbents", JOURNAL OF CHROMATOGRAPHY A, ELSEVIER, AMSTERDAM, NL, vol. 1216, no. 21, doi:10.1016/J.CHROMA.2009.03.065, ISSN 0021-9673, (20090522), pages 4589 - 4596, (20090328), XP026460269 [X] 11,12 * paragraph [03.2] - paragraph [03.4] * * page 4596, column 1, line 22 - line 29 *

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