IP Verse

Improved Immunoglobulin Variable Domains - EP3143042

The patent EP3143042 was granted to Ablynx on Jun 10, 2020. The application was originally filed on May 13, 2015 under application number EP15722211A. The patent is currently recorded with a legal status of "Opposition Rejected".

EP3143042

ABLYNX
Application Number
EP15722211A
Filing Date
May 13, 2015
Status
Opposition Rejected
Sep 27, 2024
Grant Date
Jun 10, 2020
External Links
Slate, Register, Google Patents

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Patent Citations (15) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication NumberPublication Link
INTERNATIONAL-SEARCH-REPORTWO2009138494
INTERNATIONAL-SEARCH-REPORTWO2011075861
INTERNATIONAL-SEARCH-REPORTWO2012175741
INTERNATIONAL-SEARCH-REPORTWO2013024059
OPPOSITIONWO2006122787
OPPOSITIONWO2009138494
OPPOSITIONWO2010019570
OPPOSITIONWO2011075861
OPPOSITIONWO2012175400
OPPOSITIONWO2012175741
OPPOSITIONWO2013024059
OPPOSITIONWO2013059230
OPPOSITIONWO2013116296
OPPOSITIONWO2014004427
OPPOSITIONWO2014043509

Non-Patent Literature (NPL) Citations (11) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference TextLink
EXAMINATION- STEVEN SHERIFF ET AL, "Redefining the minimal antigen- binding fragment Heavy-chain antibodies", NATURE STRUCT BIOL, (19960101), vol. 3, pages 733 - 736, XP055569172-
EXAMINATION- MUYLDERMANS S ET AL, "Recognition of antigens by single-domain antibody fragments: the superfluous luxury of paired domains", TRENDS IN BIOCHEMICAL SCIE, ELSEVIER, AMSTERDAM, NL, (20010401), vol. 26, no. 4, doi:10.1016/S0968-0004(01)01790-X, ISSN 0968-0004, pages 230 - 235, XP004241851
EXAMINATION- SERGE MUYLDERMANS, "Single domain camel antibodies: current status", REVIEWS IN MOLECULAR BIOTECHNOLOGY, NL, (20010601), vol. 74, no. 4, doi:10.1016/S1389-0352(01)00021-6, ISSN 1389-0352, pages 277 - 302, XP055277195
OPPOSITION- "Human immunoglobulin heavy chain variable region V3-20 (IGHV@) gene, exons 1-2.", IMGT/LIGM-DB, (19950515), Database accession no. M99657, URL: IMGT, XP055789945-
OPPOSITION- "Immunoglobulins", STRYER L., Biochemistry. 4th ed., W.H. Freeman & Company, (19950000), pages 368 - 370, XP055789085-
OPPOSITION- STEVEN SHERIFF et al., "Redefining the minimal antigen- binding fragment Heavy-chain antibodies", NATURE STRUCT BIOL, (19960101), vol. 3, pages 733 - 736, XP055569172-
OPPOSITION- HARMSEN et al., "Llama heavy-chain V regions consist of at least four distinct subfamilies revealing novel sequence features", Mol Immunol., (20000000), vol. 37, no. 10, doi:10.1016/S0161-5890(00)00081-X, pages 579 - 90, XP002244235
OPPOSITION- MUYLDERMANS S et al., "Recognition of antigens by single-domain antibody fragments: the superfluous luxury of paired domains", TRENDS IN BIOCHEMICAL SCIE, AMSTERDAM, NL, (20010401), vol. 26, no. 4, doi:10.1016/S0968-0004(01)01790-X, pages 230 - 235, XP004241851
OPPOSITION- SERGE MUYLDERMANS, "Single domain camel antibodies: current status", REVIEWS IN MOLECULAR BIOTECHNOLOGY, NL, (20010601), vol. 74, no. 4, doi:10.1016/S1389-0352(01)00021-6, pages 277 - 302, XP055277195
OPPOSITION- MATSUDA et al., "Structure and physical map of 64 variable segments in the 3'0.8-megabase region of the human immunoglobulin heavy-chain locus", Nat. Genet., (19930000), vol. 3, no. 1, doi:10.1038/ng0193-88, pages 88 - 94, XP000561270
OPPOSITION- NIEBA et al., "Disrupting the hydrophobic patches at the antibody variable/ constant domain interface: improved in vivo folding and physical characterization of an engineered scFv fragment", Protein Engineering, (19970000), vol. 10, no. 4, doi:10.1093/protein/10.4.435, pages 435 - 444, XP002249462

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