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Composition For Treating Or Preventing Metabolic Disease, Containing, As Active Ingredient, Extracellular Vesicles Derived From Akkermansia Muciniphila Bacteria - EP3165227

The patent EP3165227 was granted to MD Healthcare on Oct 27, 2021. The application was originally filed on May 19, 2015 under application number EP15796520A. The patent is currently recorded with a legal status of "Patent Maintained As Amended".

EP3165227

MD HEALTHCARE
Application Number
EP15796520A
Filing Date
May 19, 2015
Status
Patent Maintained As Amended
Sep 24, 2021
Grant Date
Oct 27, 2021
External Links
Slate, Register, Google Patents

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ICOSA EUROPEDec 13, 2019WILLNEGGERADMISSIBLE

Patent Citations (11) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication NumberPublication Link
INTERNATIONAL-SEARCH-REPORTKR20100120846
INTERNATIONAL-SEARCH-REPORTKR20130021920
INTERNATIONAL-SEARCH-REPORTUS2013224155
OPPOSITIONKR20100120846
OPPOSITIONKR20130021920
OPPOSITIONUS2012222142
OPPOSITIONUS2013224155
OPPOSITIONWO2014019271
OPPOSITIONWO2014076246
SEARCHUS2012222142
SEARCHWO2014019271

Non-Patent Literature (NPL) Citations (12) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference TextLink
INTERNATIONAL-SEARCH-REPORT- HANSEN, C. H. F. et al., "Early life treatment with vancomycin propagates Akkermansia muciniphila and reduces diabetes incidence in the NOD mouse", Diabetologia, (20120000), vol. 55, no. 8, ISSN 1432-0428, pages 2285 - 2294, XP035081573 [A] 1-9, 11 * . See abstract; and page 2286. *
INTERNATIONAL-SEARCH-REPORT- KANG , C. S. et al., "Extracellular vesicles derived from gut microbiota, especially Akkermansia muciniphila, protect the progression of dextran sulfate sodium-induced colitis", PLOS One, (20130000), vol. 8, no. 10, ISSN 1932-6203, page e76520, XP055106720 [A] 1-9, 11 * , inner pages 1-11. See abstract; and page 1, right column - page 2, left column and page 5. *
OPPOSITION- EVERARD et al., "Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity", Proc Natl Acad Sci USA, (20130528), vol. 110, no. 22, pages 9066 - 71-
OPPOSITION- "New research shows obesity is an inflammatory disease", FASEB Journal, (20131200), XP055662374-
OPPOSITION- HANSEN et al., "Early life treatment with vancomycin propagates Akkermansia muciniphila and reduces diabetes incidence in the NOD mouse", Diabetologia, (20120000), vol. 55, pages 2285 - 2294, XP035081573
OPPOSITION- EATON et al., "A direct comparison of experimental methods to measure dimensions of synthetic nanoparticles", Ultramicroscopy, (20170000), vol. 182, doi:10.1016/j.ultramic.2017.07.001, pages 179 - 190, XP085204010
OPPOSITION- EVERARD et al., "Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity", Proc Natl Acad Sci USA, (20130528), vol. 110, no. 22, doi:10.1073/pnas.1219451110, pages 9066 - 71, XP055074467
OPPOSITION- HOTAMISLIGIL et al., "Adipose expression of tumor necrosis factor-a: direct role in obesity-linked insulin resistance", Science, (19930101), vol. 259, doi:10.1126/science.7678183, pages 87 - 91, XP002973111
OPPOSITION- ELLIS et al., "Virulence and immunomodulatory roles of bacterial outer membrane vesicles", Microbiol Mol Biol Rev., (20100300), vol. 74, no. 1, doi:10.1128/MMBR.00031-09, pages 81 - 94, XP055107038
OPPOSITION- WELLEN et al., "Inflammation, stress, and diabetes", J. Clin. Invest, (20050502), vol. 115, pages 1111 - 1119, XP055662371
OPPOSITION- LUFT et al., "Chronic inflammation role in the obesity-diabetes association: a case-cohort study", Diabetology & Metabolic Syndrome, (20130627), vol. 5, doi:10.1186/1758-5996-5-31, page 31, XP021155894
OPPOSITION- KANG et al., "Extracellular vesicles derived from gut microbiota, especially Akkermansia muciniphila, protect the progression of dextran sulfate sodium- induced colitis", PLoS One., (20131024), vol. 8, no. 10, doi:10.1371/journal.pone.0076520, page e76520, XP055106720

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