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Dosing Regimen For Multiple Sclerosis - EP3199172

The patent EP3199172 was granted to Yeda Research on Jul 11, 2018. The application was originally filed on Aug 19, 2010 under application number EP17157735A. The patent is currently recorded with a legal status of "Revoked".

EP3199172

YEDA RESEARCH
Application Number
EP17157735A
Filing Date
Aug 19, 2010
Status
Revoked
May 10, 2024
Grant Date
Jul 11, 2018
External Links
Slate, Register, Google Patents

Patent Summary

Patent Family

Patent Family

Patent Oppositions (5)

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ALVOGEN IPCOApr 11, 2019HAMM & WITTKOPPADMISSIBLE
G L PHARMAApr 11, 2019HAMM & WITTKOPPADMISSIBLE
SYNTHONApr 11, 2019HAMM & WITTKOPPADMISSIBLE
HEXALApr 10, 2019KIESWITHDRAWN
GENERICS UK TRADING MYLANMar 25, 2019GILL JENNINGS & EVERYADMISSIBLE

Patent Citations (21) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication Number
DESCRIPTIONUS2002037848
DESCRIPTIONUS2002055466
DESCRIPTIONUS2002077278
DESCRIPTIONUS2003004099
DESCRIPTIONUS2005014694
DESCRIPTIONUS2009149541
DESCRIPTIONUS6514938
DESCRIPTIONWO0027417
DESCRIPTIONWO0160392
DESCRIPTIONWO0197846
DESCRIPTIONWO2009070298
OPPOSITIONEP1210115
OPPOSITIONEP2949335
OPPOSITIONUS2007161566
OPPOSITIONWO0020010
OPPOSITIONWO2007081975
OPPOSITIONWO2011022063
OTHEREP2405749
OTHEREP2949335
OTHERUS2007161566
SEARCHUS2007161566

Non-Patent Literature (NPL) Citations (42) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference Text
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OPPOSITION- BEJAOUI K. et al., "There is no rebound worsening of multiple sclerosis after stopping disease-modifying therapies", Multiple Sclerosis, (20080000), vol. 14, pages S 31 - S32, XP055508582
OPPOSITION- CAON et al., "Randomized, Prospective, Rater-Blinded, Four Year Pilot Study To Compare the Effect of Daily Versus Every Other Day Glatiramer Acetate 20 mg Subcutaneous Injections in RRMS", Neurology, (20090317), vol. 72, no. 11, page A317, XP009161100
OPPOSITION- "Chapter 100 Patient Compliance", Remington's Pharmaceutical Sciences, page 1813, XP055581493
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OPPOSITION- Costello Kathleen et al., "Recognizing nonadherence in patients with multiple sclerosis and maintaining treatment adherence in the long term", Medscape J Med., (20080930), vol. 10, no. 9, page 225, XP055579991
OPPOSITION- DEVONSHIRE et al., "The Global Adherence Project - A multicentre observational study on adherence to disease-modifying therapies in patients suffering from relapsing-remitting multiple sclerosis", Mult. Scler., (20061200), vol. 12, no. s1, page 316, XP055579999
OPPOSITION- "Doubling the Dose of Glatiramer Acetate Does Not Increase Efficacy", MedScape, (20080922), XP055579985
OPPOSITION- GAGNON L. POSTER, "Every-Other-Day Dosing of Glaliramer Acetate Reduces Adverse Reactions With Comparable Efficacy lo Daily Dosing: Presented al WCTRMS", WCTRIMS, (20080921), XP055580027
OPPOSITION- "Joint Meeting of the American , European , and Latin America Committees on Treatment and Research in Multiple Sclerosis (ACTRIMS, ECTRIMS, LACTRIMS", Multiple Sclerosis, (20080000), XP055580013
OPPOSITION- Jurgen Koch, "Product Life-Cycle Management for Injectable Drugs: A Good Outlook for Proactive Market Players", Pharmteceutical Technology, (20061202), URL: http://www.pharmtech.com/product-life-cycle-management-injectable-drugs-good-outl ook-proactive-market-players, XP055579996
OPPOSITION- KHAN et al., "Randomized, prospective, rater-blinded, four-year, pilot study to compare the effect of daily versus every-other-day injections in relapsing-remitting multiple", Multiple Sclerosis, (20080000), vol. 14, no. 1, page 295, XP009161078
OPPOSITION- KHAN O. et al., "P902 Randomized, prospective, rater-blinded, four-year , pilot study to compare the effect of daily versus every-other-day glatiramer acetate 20", MULTIPLE SCLEROSIS, (20080900), vol. 14, page S296, XP009161078
OPPOSITION- M. ROVARIS et al., "Results of a randomised, double-blind, parallel-group study assessing safety and efficacy of 40 mg vs. 20 mg of glatiramer acetate on MRI- measured disease activity in relapsing-remitting multiple sclerosis", Multiple Sclerosis, (20060531), vol. 12, no. 1, page 585, XP009157336
OPPOSITION- Multiple Sclerosis, (20090000), vol. 15, pages S249 - S250
OPPOSITION- Rebif@ (interferon beta-1 a
OPPOSITION- "View of NCT01067521 on 2010_02_11; A Multinational, Multicenter, Randomized, Parallel-group Study in Subjects With Relapsing-Remitting Multiple Sclerosis to Assess Efficacy, Safety and Tolerability of Glatiramer Acetate Injection 40mg Compared to Placebo in a Double-blind Design", ClinicalTrials.gov archive, (20100211), XP055465229
OPPOSITION- "View of NCT01067521 on 2010_02_11; A Multinational, Multicenter, Randomized, Parallel-group Study in Subjects With Relapsing-Remitting Multiple Sclerosis to Assess Efficacy, Safety and Tolerability of Glatiramer Acetate Injection 40mg Compared to Placebo in a Double-blind Design", Clinical Trial Study Summary (ClinicalTrials.gov archive) for NCT01067521, (20100210), XP055465229
OPPOSITION- Wee V. Yong et al., "Immunological responses to different doses of GA in MS: Analyses from the FORTE", Immunology, (20090428), vol. 72, no. 11, XP002743818
OPPOSITION- FLECHTER et al., "Comparison of glatiramer acetate (Copaxone(R)) and interferon beta-1b (Betaferon(R)) in multiple sclerosis patients: An open-label 2-year follow-up", J Neurol Sci, (20020515), vol. 197, no. 1-2, pages 51 - 55, XP002679780
OPPOSITION- CALABRESI, "Investigating glatiramer acetate for relapsing-remitting mltiple sclerosis at the double dose - is more better?", Nature Clinical Practice, (20071000), pages 540 - 541, XP055580629
OPPOSITION- FLECHTER ET et al., "Copolymer 1 (glatiramer acetate) in relapsing forms of multiple sclerosis: open multicenter study of alternate-day administration", Clin Neuropharm, (20020000), vol. 25, no. 1, pages 11 - 15, XP009161076
OPPOSITION- COHEN et al., "Randomized, double-blind, dose-comparison study of glatiramer acetate in relapsing-remitting MS.", Neurology, (20070000), vol. 68, no. 12, pages 939 - 944, XP002679784
OPPOSITION- Lizheng Shi et al., "Impact of dose frequency on compliance and health outcomes: a literature review (1966-2006)", Expert Rev. Pharmacoeconomics Outcomes Res., (20070000), vol. 7, no. 2, pages 187 - 202, XP055579988
OPPOSITION- SIMPSON et al., "Glatiramer acetate: A review of its use in relapsing-remitting multiple sclerosis.", Adis Drug Evaluation, Glatiramer Acetate, (20020000), vol. 16, no. 12, pages 925 - 850, XP009161077
OPPOSITION- GAGNON L., "Every-Other-Day Dosing of Glatiramer Acetate Reduces Adverse Reactions with Comparable Efficacy to Daily Dosing", WCTRMS, (20080921), XP055508581
OTHER- Anonymous, "Highlights of Prescribing Information Copaxone (glatiramer acetate)", (20090200), pages 2pp, 1 - 20, XP055495213
OTHER- DEVONSHIRE, "The Global Adherence Project - A multicentre observational study on adherence to disease-modifying therapies in patients suffering from relapsing-remitting multiple sclerosis", Mult. Scler., (20060000), vol. 12, no. S1, page 316
OTHER- Expert Rev. Pharmacoeconomics Outcomes Res., (20070000), vol. 7, no. 2, pages 187 - 202
OTHER- Medscape J Med., (20080930), vol. 10, no. 9, page 225
OTHER- Teva Pharmaceutical Industries, "View of NCT01067521 on 2010_02_11; A Multinational, Multicenter, Randomized, Parallel-group Study in Subjects With Relapsing-Remitting Multiple Sclerosis to Assess Efficacy, Safety and Tolerability of Glatiramer Acetate Injection 40mg Compared to Placebo in a Double-blind Design", ClinicalTrials.com archive, (20100211), URL: https://clinicaltrials.gov/archive/NCT01067521/2010_02_11, XP055465229
OTHER- G. CO MI et al., "European/Canadian Multicenter, Double-Blind, Randomized, Placebo-Controlled Study of the Effects of Glatiramer Acetate on Magnetic Resonance Imaging-Measured Disease Activity and Burden in Patients with Relapsing Multiple Sclerosis", Ann. Neurol., (20010000), vol. 49, doi:doi:10.1002/ana.64, pages 290 - 297, XP009042363
SEARCH- CAON CHRISTINA ET AL, "Randomized, Prospective, Rater-Blinded, Four Year Pilot Study To Compare the Effect of Daily Versus Every Other Day Glatiramer Acetate 20 mg Subcutaneous Injections in RRMS", NEUROLOGY, & 61ST ANNUAL MEETING OF AMERICAN-ACADEMY-OF-NEUROLOGY; SEATTLE, WA, USA; APRIL 28 -29, 2009, (200903), vol. 72, no. 11, Suppl. 3, ISSN 0028-3878, page A317, XP009161100 [A] 1-12 * abstract *
SEARCH- KHAN O ET AL, "Randomized, prospective, rater-blinded, four-year, pilot study to compare the effect of daily versus every - other - day injections in relapsing -remitting multiple", MULT.SCLER. (14, SUPPL. 1, S296, 2008) 0 REF. ISSN: 1352-4585 AV - WAYNE STATE UNIV, SCH MED, DETROIT, MI, USA., (2008), XP009161078 [A] 1-12 * abstract *
SEARCH- FLECHTER S ET AL, "Comparison of glatiramer acetate (Copaxone(R)) and interferon beta-1b (Betaferon(R)) in multiple sclerosis patients: An open-label 2-year follow-up", JOURNAL OF THE NEUROLOGICAL SCIENCES, (20020515), vol. 197, no. 1-2, ISSN 0022-510X, pages 51 - 55, XP002679780 [A] 1-12 * abstract *
SEARCH- FLECHTER SHLOMO ET AL, "Copolymer 1 (glatiramer acetate) in relapsing forms of multiple sclerosis: open multicenter study of alternate-day administration.", CLINICAL NEUROPHARMACOLOGY 2002 JAN-FEB LNKD- PUBMED:11852290, (200201), vol. 25, no. 1, ISSN 0362-5664, pages 11 - 15, XP009161076 [A] 1-12 * abstract * * "Comparison of daily with alternate-day treatment" on page 14 and "Drug Supply" on page 12 *
SEARCH- COHEN J A ET AL, "Randomized, double-blind, dose-comparison study of glatiramer acetate in relapsing-remitting MS.", NEUROLOGY 20 MAR 2007 LNKD- PUBMED:17372130, (20070320), vol. 68, no. 12, ISSN 1526-632X, pages 939 - 944, XP002679784 [A] 1-12 * abstract *
SEARCH- SIMPSON DENE ET AL, "Glatiramer acetate: A review of its use in relapsing-remitting multiple sclerosis.", CNS DRUGS, (2002), vol. 16, no. 12, ISSN 1172-7047, pages 825 - 850, XP009161077 [A] 1-12 * "Therapeutic efficacy" on page 835 and "Dosage and Administration" on page 844 * * table II *

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