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Animal Models And Therapeutic Molecules - EP3241435

The patent EP3241435 was granted to Kymab on May 26, 2021. The application was originally filed on Jul 7, 2010 under application number EP17174426A. The patent is currently recorded with a legal status of "Granted And Under Opposition".

EP3241435

KYMAB
Application Number
EP17174426A
Filing Date
Jul 7, 2010
Status
Granted And Under Opposition
Apr 23, 2021
Grant Date
May 26, 2021
External Links
Slate, Register, Google Patents

Patent Summary

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REGENERON PHARMACEUTICALSFeb 25, 2022J A KEMPWITHDRAWN

Patent Citations (6) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication NumberPublication Link
OPPOSITIONWO02066630
OPPOSITIONWO2009076464
OPPOSITIONWO2010039900
SEARCHUS2006015957
SEARCHWO02066630
SEARCHWO2007117410

Non-Patent Literature (NPL) Citations (13) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference TextLink
OPPOSITION- MACDONALD et al., "VELOCIGENE TECHNOLOGY EXTENDED TO HUMANIZATION OF SEVERAL MEGABASES OF COMPLEX GENE LOCI", 1st International MUGEN conference on Animal Models, Athens Greece, (20060000), XP055304452-
OPPOSITION- STEVENS et al., "VeloclmmuneTM: Humanization of immunoglobulin loci using VelociGene® technology", 1st International MUGEN conference on Animal Models, Athens Greece, (20060000), XP055670579-
OPPOSITION- QU et al., "Gene targeting of ErbB using a Cre-mediated unidirectional DNA inversion strategy", Genesis, (20060000), vol. 44, doi:10.1002/dvg.20243, pages 477 - 486, XP055500670
OPPOSITION- MURPHY, "Recombinant Antibodies in Immunotherapy", Melvyn Little, (20090000), XP055304492
OPPOSITION- LEE et al., "Complete humanisation of the mouse immunoglobulin loci enables efficient therapeutic antibody discovery", Nature Biotechnology, (20140000), vol. 32, page 356, XP055131583
OPPOSITION- OBERDOERFFER et al., "Unidirectional cre-mediated genetic inversion in mice using the mutant loxP pair lox66/lox71", Nucleic Acids Research, (20030000), vol. 31, no. 22, doi:10.1093/nar/gng140, pages 1 - 7, XP002992914
OPPOSITION- UNGRIN et al., "Strict control of telomerase activation using Cre mediated inversion", BMC Biotechnology, (20060000), vol. 6, no. 10, doi:10.1186/1472-6750-6-10, pages 1 - 9, XP002762660
OTHER- BRUGGEMANN, "Human antibody expression in transgenic mice", Archivum Immunologiae et Therapiae Experimentalis, (20010000), vol. 49, pages 203 - 208, XP009039754-
OTHER- Murphy A, "Chapter 8 - Velicimmune: Immunoglobulin Variable Region Humanized Mice", Murphy A, Melvyn Little, Recombinant Antibodies in Immunotherapy, Cambridge University Press, (20090000), pages 100 - 107, ISSN 978-0-521-88732-8, XP055308821-
OTHER- Macdonald L E; Karow M; Stevens S; Auerbach W; Poueymirou W T; Yasenchak J; Frendewey D; Valenzuela D M; Giallourakis C C; Alt F W; Yancopoulos G D; Murphy A J, "Precise and in situ genetic humanization of 6 Mb of mouse immunoglobulin genes", Proceedings of the National Academy of Sciences,, (20140000), vol. 111, no. 14, pages 5147 - 5152, XP055126064
SEARCH- YOKO TANIMOTO ET AL, "Embryonic Stem Cells Derived from C57BL/6J and C57BL/6N Mice", COMP MED, (2008), vol. 58, pages 347 - 352, XP055403872 [Y] 12 * page 349 - page 351 *-
SEARCH- JUAN RIVERA ET AL, "Genetic Background and the Dilemma of Translating Mouse Studies to Humans", IMMUNITY., US, (2008), vol. 28, no. 1, doi:10.1016/j.immuni.2007.12.008, ISSN 1074-7613, pages 1 - 4, XP055403880 [Y] 12 * page 1 *
SEARCH- OBERDOERFFER P ET AL, "Unidirectional Cre-mediated genetic inversion in mice using the mutant loxP pair lox66/lox71", NUCLEIC ACIDS RESEARCH, INFORMATION RETRIEVAL LTD, (2003), vol. 31, no. 22, doi:10.1093/NAR/GNG140, ISSN 0305-1048, pages 1 - 7, XP002992914 [Y] 8 * figure 1 *

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