Method For Regulating Glycosylation Of Recombinant Glycoprotein - EP3241908

The patent EP3241908 was granted to LG Chem on Aug 5, 2020. The application was originally filed on Dec 30, 2015 under application number EP15875732A. The patent is currently recorded with a legal status of "Revoked".

EP3241908

LG CHEM
Application Number
EP15875732A
Filing Date
Dec 30, 2015
Status
Revoked
Jun 24, 2022
Publication Date
Aug 5, 2020
External Links
Slate, Register, Google Patents

Patent Summary

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Patent Oppositions (2)

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MAIWALDMay 5, 2021LASARADMISSIBLE
NEUEFEINDMay 4, 2021NEUEFEINDADMISSIBLE

Patent Citations (20) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication Number
EXAMINATIONWO9639488
INTERNATIONAL-SEARCH-REPORTKR20090029841
INTERNATIONAL-SEARCH-REPORTKR20110139292
INTERNATIONAL-SEARCH-REPORTUS2012276631
INTERNATIONAL-SEARCH-REPORTWO2015026846
INTERNATIONAL-SEARCH-REPORTWO9961650
OPPOSITIONUS7294481
OPPOSITIONWO2006026447
OPPOSITIONWO2008008360
OPPOSITIONWO2008033517
OPPOSITIONWO2008109410
OPPOSITIONWO2010122460
OPPOSITIONWO2010138502
OPPOSITIONWO2014145091
OPPOSITIONWO2014195452
OPPOSITIONWO2015026846
OPPOSITIONWO9639488
OPPOSITIONWO9961650
SEARCHWO2011099028
SEARCHWO9639488

Non-Patent Literature (NPL) Citations (12) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference Text
OPPOSITION- LEFLOCH et al., "Related effects of cell adaptation to serum-free conditions on murine EPO production and glycosylation by CHO cells", Cytotechnology, (20060000), vol. 52, pages 39 - 53, XP019478997
OPPOSITION- "N-linked glycosylation", Wikipedia, (20210401), URL: https://en.wikipedia.org/wiki/N-linked_glycosylation, XP055808351
OPPOSITION- "O-linked glycosylation", Wikipedia, (20210205), URL: https://en.wikipedia.org/wiki/O-linked_glycosylation, XP055808356
OPPOSITION- RESTELLI et al., "THE EFFECT OF CELL CULTURE PARAMETERS ON PROTEIN GLYCOSYLATION", CELL ENGINEERING, (20020000), vol. 3, pages 61 - 92, XP001203473
OPPOSITION- OLIVEIRA et al., "ROLE OF EXTRACELLULAR SIGNALING ON ENDOTHELIAL CELL PROLIFERATION AND PROTEIN N-GLYCOSYLATION", J. Cell. Physiol., (19900000), vol. 144, pages 467 - 472, XP000946498
OPPOSITION- Liming Liu, "Antibody Glycosylation and Its Impact on the Pharmacokinetics and Pharmacodynamics of Monoclonal Antibodies and Fc-Fusion Proteins", J. Pharm. Sci., (20150000), vol. 104, pages 1866 - 1884, XP055295176
OPPOSITION- Huifeng Zhang; Haibin Wang; Mei Liu; Tao Zhang; Ji Zhang; Xiangjing Wang; Wensheng Xiang, "Rational development of serum-free medium and fed-batch process for a GS*CHO cell line expressing recombinant antibody", Cytotechnol, (20130000), vol. 65, pages 363 - 378, XP055615804
OPPOSITION- GAWLITZEK et al., "Characterization of changes in the glycosylation pattern of recombinant proteins from BHK-21 cells due to different culture conditions", J. Biotechnology, (19950000), vol. 42, pages 117 - 131, XP004036908
OPPOSITION- LEE et al., "The pharmacology study of a new recombinant TNF receptor-hyFc fusion protein", Biologicals, (20130000), vol. 41, pages 77 - 83, XP029001046
OPPOSITION- Stephane Houel; Mark Hilliard; Ying Qing Yu; Niaobh McLoughlin; Silvia Millan Martin; Pauline M Rudd; Jonathan P Williams; Weibin Chen, "N- and O-Glycosylation Analysis of Etanercept Using Liquid Chromatography and Quadrupole Time-of-Flight Mass Spectrometry Equipped with Electron-Transfer Dissociation Functionality", Anal. Chem., (20131205), vol. 86, pages 576 - 584, XP002738666
OPPOSITION- SERRATO et al., "Differences in the glycosylation profile of a monoclonal antibody produced by hybridomas cultured in serum-supplemented, serum-free or chemically defined media", Biotechnol. Appl. Biochem., (20070000), vol. 47, pages 113 - 124, XP002716095
OPPOSITION- Qingqiao Tan; Qingcheng Guo; Chen Fang; Chong Wang; Bohua Li; Hao Wang; Jing Li; Yajun Guo, "Characterization and comparison of commercially available TNF receptor 2-Fc fusion protein products", mAbs, (20120000), vol. 4, pages 761 - 774, XP055285200

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