Recombinant Adeno-Associated Virus Particle Purification With Multiple-Step Anion Exchange Chromatography - EP3256573

The patent EP3256573 was granted to Association Franaise Contre LES Myopathies on Dec 9, 2020. The application was originally filed on Feb 9, 2016 under application number EP16704575A. The patent is currently recorded with a legal status of "Granted And Under Opposition".

EP3256573

ASSOCIATION FRANAISE CONTRE LES MYOPATHIES
Application Number
EP16704575A
Filing Date
Feb 9, 2016
Status
Granted And Under Opposition
Nov 6, 2020
Publication Date
Dec 9, 2020
External Links
Slate, Register, Google Patents

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D YOUNGSep 9, 2021D YOUNGADMISSIBLE

Patent Citations (17) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication Number
DESCRIPTIONUS5139941
DESCRIPTIONUS5173414
DESCRIPTIONUS6376237
DESCRIPTIONWO03097797
DESCRIPTIONWO2011094198
DESCRIPTIONWO9201070
DESCRIPTIONWO9303769
INTERNATIONAL-SEARCH-REPORTWO2010148143
INTERNATIONAL-SEARCH-REPORTWO2011094198
OPPOSITIONWO2004020971
OPPOSITIONWO2007059473
OPPOSITIONWO2007134325
OPPOSITIONWO2011094198
OTHEREP3256573
OTHERUS2001043916
OTHERUS2004106184
OTHERWO0212455

Non-Patent Literature (NPL) Citations (16) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference Text
EXAMINATION- BRUMENT ET AL, MOLECULAR THERAPY, (2002), vol. 6, page 678
EXAMINATION- Millistak+ HC Pod filter data sheet
EXAMINATION- Opticap XL10 Express SHC filter data sheet
EXAMINATION- Polygard CN data sheet
EXAMINATION- Polysep II data sheet
EXAMINATION- WANG ET AL, MOLECULAR THERAPY, (2008), vol. 16, page S291
OPPOSITION- Barbara A Thorne, Takeya Ryan K, Peluso Richard W, "Review Manufacturing Recombinant Adeno-Associated Viral Vectors from Producer Cell Clones", HUMAN GENE THERAPY, (20090713), vol. 20, pages 707 - 714, XP055182370
OPPOSITION- "chapter 1 and 2", ION EXCHANGE CHROMATOGRAPHY & CHROMATOFOCUSING PRINCIPLE AND METHODS HANDBOOK, (2014), XP055844663
OPPOSITION- PETIT et al., "Restoration of Vision in the pde6P-deficient Dog,a Large Animal Model of Rod-cone Dystrophy", Molecular Therapy, (20120000), vol. 20, no. 11, pages 2019 - 2030, XP055844666
OPPOSITION- Piergiuseppe Nestola et al, "Improved virus purification processes for vaccines and gene therapy", Biotechnology and Bioengineering, Hoboken, USA, (20150510), vol. 112, no. 5, doi:10.1002/bit.25545, ISSN 0006-3592, pages 843 - 857, XP055265059
OPPOSITION- QU et al., "Separation of adeno-associated virus type 2 empty particles from genome containing vectors by anion-exchange column chromatography", Journal of Virological Methods, (20070000), vol. 140, pages 183 - 192, XP005870426
OPPOSITION- ZHOU et al., "PEG-modulated column chromatography for purification of recombinant adeno-associated virus serotype 9", Journal of Virological Methods, (20110000), vol. 173, pages 99 - 107, XP028162981
OPPOSITION- URABE et al., "Removal of Empty Capsids from Type 1 Adeno-Associated Virus Vector Stocks by Anion-Exchange Chromatography Potentiates Transgene Expression", Molecular Therapy, (20060000), vol. 13, no. 4, pages 823 - 828, XP005358617
OPPOSITION- Nathalie Clement, Joshua C Grieger, "Manufacturing of recombinant adeno-associated viral vectors for clinical trials", Molecular therapy- methods & clinical development, Nature Publishing Group, GB, GB , (20160101), vol. 3, doi:10.1038/mtm.2016.2, ISSN 2329-0501, page 16002, XP055387003
OPPOSITION- ALLAY et al., "Good Manufacturing Practice Production of Self-Complementary Serotype 8 Adeno-Associated Viral Vector for a Hemophilia B Clinical Trial", Human gene Therapy, (20110000), vol. 22, pages 595 - 604, XP055349809
OPPOSITION- QU et al., "Scalable Downstream Strategies for Purification of Recombinant Adeno- Associated Virus Vectors in Light of the Properties", Current Pharmaceutical Biotechnology, (20150000), vol. 16, pages 684 - 695, XP055533837

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