Aluminium Compounds For Use In Therapeutics And Vaccines - EP3269386

The patent EP3269386 was granted to Valneva Austria on Sep 14, 2022. The application was originally filed on Dec 6, 2012 under application number EP17185526A. The patent is currently recorded with a legal status of "Granted And Under Opposition".

EP3269386

VALNEVA AUSTRIA
Application Number
EP17185526A
Filing Date
Dec 6, 2012
Status
Granted And Under Opposition
Aug 12, 2022
Grant Date
Sep 14, 2022
External Links
Slate, Register, Google Patents

Patent Summary

Patent Family

Patent Family

Patent Oppositions

Patent oppositions filed by competitors challenge the validity of a granted patent. These oppositions are typically based on claims of prior art, lack of novelty, or non-obviousness. They are a key part of the process for determining a patent's strength and enforceability.

CompanyOpposition DateRepresentativeOpposition Status

Get instant alerts for new oppositions and patent status changes

MAIWALDJun 13, 2023MAIWALDADMISSIBLE

Patent Citations (22) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication NumberPublication Link
DESCRIPTIONCN101734698
DESCRIPTIONEP0497524
DESCRIPTIONEP0497525
DESCRIPTIONUS4057685
DESCRIPTIONUS4459286
DESCRIPTIONUS4663160
DESCRIPTIONUS4673574
DESCRIPTIONUS4695624
DESCRIPTIONUS4761283
DESCRIPTIONUS4761372
DESCRIPTIONUS4808700
DESCRIPTIONUS4882317
DESCRIPTIONUS4965338
DESCRIPTIONUS5308835
DESCRIPTIONWO0010599
DESCRIPTIONWO02064162
DESCRIPTIONWO9814401
DESCRIPTIONWO9842375
OPPOSITIONEP1604685
OTHEREP2788023
OTHEREP3106176
SEARCHUS2005158334

Non-Patent Literature (NPL) Citations (53) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference TextLink
DESCRIPTION- ALIPAZAGA MV; MORENO RGM; COICHEV N., "Synergistic effect of Ni(II) and Co(II) ions on the sulphite induced autoxidation of Cu(II)/tetraglycine complex", Dalton Trans, (20040000), vol. 13, pages 2036 - 2040-
DESCRIPTION- BERGLUND J; FRONAEUS S; ELDING LI, "Kinetics and mechanism for manganese-catalyzed oxidation of sulfur(IV) by oxygen in aqueous solution", Inorg Chem, (19930000), vol. 32, pages 4527 - 4538-
DESCRIPTION- BURNOUF T, Vox Sang., (19910000), vol. 60, pages 8 - 15-
DESCRIPTION- CHEMICAL ABSTRACTS, Database accession no. 21645-51-2-
DESCRIPTION- EXLEY, C, Trends in Immunol., (20100000), vol. 31, pages 103 - 109-
DESCRIPTION- GEVER et al., Med. Microbiol. Immunol, (19790000), vol. 165, pages 171 - 288-
DESCRIPTION- HUIE R.E.; NETA P, "One-electron redox reaction in aqueous solutions of sulphite with hydroquinone and other hydroxyphenols", J. Phys. Chem., (19850000), vol. 89, no. 18, pages 3918 - 3921-
DESCRIPTION- ITO, KIMIKO; KAWANASHI, SHOSUKE, "Site-specific fragmentation and modification of Albumin by sulphite in presence of metal ions or peroxidase/H202: Role of Sulphate radical", Biochem and Biophys Res Comm., (19910000), vol. 176, pages 1306 - 1312-
DESCRIPTION- JONES et al., An. Acad. Bras. Cienc, (20050000), vol. 77, no. 2, pages 293 - 324-
DESCRIPTION- KALINA RANGUELOVA; MARCELO G. BONINI; RONALD P, "Mason: (Bi)sulphite Oxidation by Copper,Zinc-Superoxide Dismutase: Sulphite- Derived, Radical-Initiated Protein Radical Formation", Environmental Health Perspectives, (20100000), vol. 118, no. 7, pages 970 - 975-
DESCRIPTION- LAMBETH D.O.; PALMER G., "The kinetics and mechanism of reduction of electron transfer proteins and other compounds of biological interest by dithionite", J.Biochem. Chem., (19730000), vol. 248, pages 6095 - 6103-
DESCRIPTION- LIMA S; BONIFACIO RL; AZZELLINI GC; COICHEV N., "Ruthenium(II) tris(bipyridyl) ion as a luminescent probe for oxygen uptake on the catalyzed oxidation of HS0", Talanta, (20020000), vol. 56, pages 547 - 556-
DESCRIPTION- LIN C.-W.; WU W.-C., J Virol., (20030000), vol. 77, no. 4, pages 2600 - 6-
DESCRIPTION- LINDBLAD, EB, Immunol. and Cell Biol., (20040000), vol. 82, pages 497 - 505-
DESCRIPTION- NETA P.; HUIE R.E., "Free Radical Chemistry of Sulphite", Environmental Health Perspectives, (19850000), vol. 64, pages 209 - 217-
DESCRIPTION- ROBBINS et al., JAMA, (19960000), vol. 276, no. 14, pages 1181 - 5-
DESCRIPTION- SHI X., "Generation of • SO and OH radicals in SO reactions with inorganic environmental pollutants and its implications to SO toxicity", J Inorg Biochem, (19940000), vol. 56, no. 3, pages 155 - 165-
DESCRIPTION- LI S; SCHONEICH C; BORCHARDT RT, "Chemical instability of protein pharmaceuticals: Mechanisms of oxidation and strategies for stabilization", Biotechnol Bioeng, (19951205), vol. 48, no. 5, doi:doi:10.1002/bit.260480511, pages 490 - 500, XP055040145
DESCRIPTION- STADTMAN ER., "Metal ion-catalyzed oxidation of proteins: biochemical mechanism and biological consequences", Free Radic Biol Med., (19900000), vol. 9, no. 4, doi:doi:10.1016/0891-5849(90)90006-5, pages 315 - 25, XP023548593
DESCRIPTION- ARUNEE WITTAYANUKULLUK; DONGPING JIANG; FRED E. REGNIER; STANLEY L. HEM, "Effect of microenvironment pH of aluminum hydroxide adjuvant on the chemical stability of adsorbed antigen", Vaccine, (20040000), vol. 22, doi:doi:10.1016/j.vaccine.2003.09.037, pages 1172 - 1176, XP004493380
DESCRIPTION- MAYO JC; TAN DX; SAINZ RM; NATARAJAN M; LOPEZ-BURILLO S; REITER RJ, "Protection against oxidative protein damage induced by metal-catalyzed reaction or alkylperoxyl radicals: comparative effects of melatonin and other antioxidants", Biochim Biophys Acta, (20030317), vol. 1620, no. 1-3, doi:doi:10.1016/S0304-4165(02)00527-5, pages 139 - 50, XP004410890
DESCRIPTION- BRANDT C; ELDING LI, "Role of chromium and vanadium in the atmospheric oxidation of sulfur (IV", Atmos Environ, (19980000), vol. 32, no. 4, doi:doi:10.1016/S1352-2310(97)00331-2, pages 797 - 800, XP004890864
EXAMINATION- (20180709), Williamson Research Centre Wiki, URL: http://wiki.manchester.ac.uk/wrc/index.php/ICP-MS-
EXAMINATION- ICP-MS Agilent Series 7500 product description (20.03.2007)-
EXAMINATION- Shihong Li ET AL, "Chemical instability of protein pharmaceuticals: Mechanisms of oxidation and strategies for stabilization", Biotechnology and Bioengineering, (19951205), vol. 48, no. 5, doi:10.1002/bit.260480511, ISSN 0006-3592, pages 490 - 500, XP055040145
EXAMINATION- ITO K ET AL, "Site-specific fragmentation and modification of albumin by sulfite in the presence of metal ions or peroxidase/H"2O"2: Role of sulfate radical", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ELSEVIER, AMSTERDAM, NL, vol. 176, no. 3, doi:10.1016/0006-291X(91)90428-A, ISSN 0006-291X, (19910515), pages 1306 - 1312, (19910515), XP024835944
EXAMINATION- STADTMAN ET AL, "Metal ion-catalyzed oxidation of proteins: Biochemical mechanism and biological consequences", FREE RADICAL BIOLOGY AND MEDICINE, ELSEVIER INC, US, vol. 9, no. 4, doi:10.1016/0891-5849(90)90006-5, ISSN 0891-5849, (19900101), pages 315 - 325, (19900101), XP023548593
EXAMINATION- MAYO J C ET AL, "Protection against oxidative protein damage induced by metal-catalyzed reaction or alkylperoxyl radicals: comparative effects of melatonin and other antioxidants", BIOCHIMICA ET BIOPHYSICA ACTA (BBA) - GENERAL SUBJ, ELSEVIER, AMSTERDAM, NL, (20030317), vol. 1620, no. 1-3, doi:10.1016/S0304-4165(02)00527-5, ISSN 0304-4165, pages 139 - 150, XP004410890
OPPOSITION- Anonymous, "Aluminium hydroxide, hydrated, for adsorption ", European Pharmacopeia 6.0, (20080101), pages 1150 - 1150, XP093122208-
OPPOSITION- Anonymous, "Assessment report for IXIARO", EMA European Medicines Agency, (20120525), pages 1 - 8, XP093122139-
OPPOSITION- Anonymous, "Assessment report for ixiaro ", EMEA European Medicines Agency, (20090101), no. EMEA/H/C/000963, pages 1 - 50, XP093122019-
OPPOSITION- Anonymous, "European Medicines Agency recommends revaccination for some travellers in need of protection with Ixiaro", EMA European Medicines Agency, (20110527), pages 1 - 2, XP093122125-
OPPOSITION- Anonymous, "Guidance for Industry Drug Stability Guidelines ", U.S. Department of Health and Human Services Food and Drug Administration Center for Veterinary Medicine (CVM), (20081209), pages 1 - 51, XP093122175-
OPPOSITION- Anonymous, "Guidance for Industry Investigating Out-of-Specification (OOS) Test Results for Pharmaceutical Production", U.S. Department of Health and Human Services Food and Drug Administration Center for Drug Evaluation and Research (CDER), (20061001), pages 1 - 17, XP093122146-
OPPOSITION- Anonymous, "Highlights of prescribing information", IXIARO, (20100901), pages 1 - 13, XP093122133-
OPPOSITION- Anonymous, "Ixiaro Procedural steps taken and scientific information after the authorisation", Procedural steps taken and scientific information after the authorisation, EMEA European Medicines Agency, (20210408), pages 1 - 30, Procedural steps taken and scientific information after the authorisation, URL: https://www.ema.europa.eu/en/documents/procedural-steps-after/ixiaro-epar-procedural-steps-taken-and-scientific-information-after-authorisation_en.pdf, XP093178902-
OPPOSITION- Anonymous, "Poliomyelitis vaccine (inactivated)", Anonymous, European Directorate for the Quality of Medicines and HealthCare (EDQM), European Pharmacopoeia; Monograph 214, European Pharmacopoeia Commission , (20010101), pages 2206 - 2209, XP009555192-
OPPOSITION- Anonymous, "Resume des caracteristiques du produit ", (20101112), pages 1 - 5, ANSM , URL: http://agence-prd.ansm.sante.fr/php/ecodex/rcp/R0184995.htm, (20240122), XP093122169-
OPPOSITION- Srivastava, A.K. ; Putnak, J. ; Lee, S.H. ; Hong, S.P. ; Moon, S.B. ; Barvir, D.A. ; Zhao, B. ; Olson, R.A. ; Kim, S.O. ; Yoo, W.D. ; Towle, A.C. ; Vaughn, D.W. ; Innis, B.L. ; Eckels, K.H., "A purified inactivated Japanese encephalitis virus vaccine made in vero cells", Vaccine, AMSTERDAM, NL , (20010814), vol. 19, no. 31, ISSN 0264-410X, pages 4557 - 4565, XP027321987-
OPPOSITION- Traveladmin, "Vaccine Recall- IXIARO- Japanese Encephalitis", Travel Clinic Biog, (20110614), pages 1 - 2, XP093122223-
OPPOSITION- Salinas Branden A., Sathish Hasige A., Shah Ambarish U., Carpenter John F., Randolph Theodore W., "Buffer-Dependent Fragmentation of a Humanized Full-Length Monoclonal Antibody", Journal of Pharmaceutical Sciences, US , (20100701), vol. 99, no. 7, doi:10.1002/jps.22056, ISSN 0022-3549, pages 2962 - 2974, XP093122010
OPPOSITION- Earl R Stadtman, "Metal ion-catalyzed oxidation of proteins: Biochemical mechanism and biological consequences", Free Radical Biology & Medicine, US , (19900101), vol. 9, no. 4, doi:10.1016/0891-5849(90)90006-5, ISSN 0891-5849, pages 315 - 325, XP023548593
OPPOSITION- Robert Schlegl, Michael Weber, Jürgen Wruss, Donald Low, Kirsten Queen, Shaun Stilwell, Erik B. Lindblad, Michael Möhlen, "Influence of elemental impurities in aluminum hydroxide adjuvant on the stability of inactivated Japanese Encephalitis vaccine, IXIARO®", Vaccine, AMSTERDAM, NL , (20151101), vol. 33, no. 44, doi:10.1016/j.vaccine.2015.05.103, ISSN 0264-410X, pages 5989 - 5996, XP055315021
OPPOSITION- Doel T.R., Osterhaus A.D.M.E., Van Wezel A.L., Van Steenis G., "The evaluation of a physical method for the quantification of inactivated poliovirus particles and its relationship to D-antigenicity and potency testing in rats", JOURNAL OF BIOLOGICAL STANDARDIZATION., ACADEMIC PRESS, LONDON., GB, GB , (19840101), vol. 12, no. 1, doi:10.1016/S0092-1157(84)80025-6, ISSN 0092-1157, pages 93 - 99, XP093178901
OPPOSITION- Anonymous, "Phosphate-buffered saline (PBS)", Cold Spring Harbor Protocols, US , (20060602), doi:10.1101/pdb.rec8247, ISSN 1559-6095, pages 1 - 1, XP093117074
OPPOSITION- Lin Cheng-Wen, Wu Suh-Chin, "A Functional Epitope Determinant on Domain III of the Japanese Encephalitis Virus Envelope Protein Interacted with Neutralizing-Antibody Combining Sites", Journal of Virology, US , (20030215), vol. 77, no. 4, doi:10.1128/JVI.77.4.2600-2606.2003, ISSN 0022-538X, pages 2600 - 2606, XP093122000
OTHER- Anonyme, "DULTAVAX, suspension injectable en seringue préremplie. Vaccin diphtérique, tétanique et poliomyélitique (inactivé), (adsorbé)", ansm, (20101112), page 7pp, ansm, URL: http://agence-prd.ansm.sante.fr/php/ecodex/frames.php?specid=67968260&typedoc=N&ref=N0184995.htm, (20190711), XP055604556-
OTHER- L'Ansm, "DULTAVAX", résumé des caractéristiques du produit, (20101112), pages 1 - 6, URL: http://agence-prd.ansm.sante.fr/php/ecodex/rcp/R0184995.htm, XP055896496-
SEARCH- ANONYMOUS, "Rehydragel Adjuvants. Product profile", (2008), pages 1 - 2, General Chemical, URL: http://www.generalchemical.com/assets/pdf/Rehydragel_Adjuvants_Product_Profile.pdf, (20121008), XP002684848 [A] 1-15 * the whole document *-
SEARCH- LI S; SCHONEICH C; BORCHARDT RT, "Chemical instability of protein pharmaceuticals: Mechanisms of oxidation and strategies for stabilization.", BIOTECHNOL BIOENG., (19951205), vol. 48, no. 5, pages 490 - 500, XP055040145 [DA] 1-15 * abstract * * page 491, column l, paragraph 2 - paragraph 3 * * page 497, column r, paragraph 3 *
SEARCH- TIA ESTEY ET AL, "Evaluation of chemical degradation of a trivalent recombinant protein vaccine against botulinum neurotoxin by LysC peptide mapping and MALDI-TOF mass spectrometry", JOURNAL OF PHARMACEUTICAL SCIENCES, (20090901), vol. 98, no. 9, doi:10.1002/jps.21543, ISSN 0022-3549, pages 2994 - 3012, XP055040203 [A] 1-15 * abstract * * page 2995, column l, paragraph 1 - column r, paragraph 1 * * page 2996, column r, paragraph 2 - page 2997, column l, paragraph 4 *
SEARCH[ ] - ROBERT SCHLEGL ET AL, "Influence of elemental impurities in aluminum hydroxide adjuvant on the stability of inactivated Japanese Encephalitis vaccine, IXIARO", VACCINE, GB, (20151101), vol. 33, no. 44, doi:10.1016/j.vaccine.2015.05.103, ISSN 0264-410X, pages 5989 - 5996, XP055315021
SEARCH- LINDBLAD, EB, "Special feature. Aluminium compounds for use in vaccines", IMMUNOL. AND CELL BIOL., (2004), vol. 82, pages 497 - 505, XP008151421 [DA] 1-15 * the whole document *

Download Citation Report

Get a free citation report including examiner, opposition, and international search citations.

Get Citation Report

Dossier Documents

The dossier documents provide a comprehensive record of the patent’s prosecution history - including filings, correspondence, and decisions made by patent offices - and are crucial for understanding the patent’s legal journey and any challenges it may have faced during examination.

  • Date

    Description

  • Get instant alerts for new documents