The patent EP3283882 was granted to Merck Sharp & Dohme on Oct 16, 2024. The application was originally filed on Apr 12, 2016 under application number EP16780526A. The patent is currently recorded with a legal status of "Patent Maintained As Amended".

Patent oppositions filed by competitors challenge the validity of a granted patent. These oppositions are typically based on claims of prior art, lack of novelty, or non-obviousness. They are a key part of the process for determining a patent's strength and enforceability.
Patent citations refer to prior patents cited during different phases such as opposition or international search.
| Citation Phase | Publication Number |
|---|---|
| DESCRIPTION | WO2014US70232 |
| DESCRIPTION | WO2014US70236 |
| DESCRIPTION | WO2014US70237 |
| DESCRIPTION | US2015071910 |
| DESCRIPTION | US4816567 |
| DESCRIPTION | US5143854 |
| DESCRIPTION | US5242974 |
| DESCRIPTION | US5288644 |
| DESCRIPTION | US5324633 |
| DESCRIPTION | US5384261 |
| DESCRIPTION | US5405783 |
| DESCRIPTION | US5412087 |
| DESCRIPTION | US5424186 |
| DESCRIPTION | US5429807 |
| DESCRIPTION | US5432049 |
| DESCRIPTION | US5436327 |
| DESCRIPTION | US5445934 |
| DESCRIPTION | US5470710 |
| DESCRIPTION | US5472672 |
| DESCRIPTION | US5492806 |
| DESCRIPTION | US5503980 |
| DESCRIPTION | US5510270 |
| DESCRIPTION | US5525464 |
| DESCRIPTION | US5527681 |
| DESCRIPTION | US5529756 |
| DESCRIPTION | US5545531 |
| DESCRIPTION | US5547839 |
| DESCRIPTION | US5554501 |
| DESCRIPTION | US5556752 |
| DESCRIPTION | US5561071 |
| DESCRIPTION | US5571639 |
| DESCRIPTION | US5580732 |
| DESCRIPTION | US5593839 |
| DESCRIPTION | US5624711 |
| DESCRIPTION | US5631734 |
| DESCRIPTION | US5661028 |
| DESCRIPTION | US5700637 |
| DESCRIPTION | US5744305 |
| DESCRIPTION | US5770456 |
| DESCRIPTION | US5770722 |
| DESCRIPTION | US5837832 |
| DESCRIPTION | US5848659 |
| DESCRIPTION | US5856101 |
| DESCRIPTION | US5874219 |
| DESCRIPTION | US5885837 |
| DESCRIPTION | US5919523 |
| DESCRIPTION | US6022963 |
| DESCRIPTION | US6077674 |
| DESCRIPTION | US6156501 |
| DESCRIPTION | US7521051 |
| DESCRIPTION | US8008449 |
| DESCRIPTION | US8354509 |
| DESCRIPTION | US8383796 |
| DESCRIPTION | WO2008156712 |
| DESCRIPTION | WO2010027827 |
| DESCRIPTION | WO2010077634 |
| DESCRIPTION | WO2011066342 |
| DESCRIPTION | WO2012135408 |
| DESCRIPTION | WO2013019906 |
| DESCRIPTION | WO2014009535 |
| DESCRIPTION | WO9820019 |
| DESCRIPTION | WO9820020 |
| INTERNATIONAL-SEARCH-REPORT | US2013178391 |
| INTERNATIONAL-SEARCH-REPORT | US2014220580 |
| INTERNATIONAL-SEARCH-REPORT | US2015071910 |
| INTERNATIONAL-SEARCH-REPORT | WO2015016718 |
| INTERNATIONAL-SEARCH-REPORT | WO2015094992 |
| OPPOSITION | CA2905798 |
| OPPOSITION | EP2535354 |
| OPPOSITION | US2013034540 |
| OPPOSITION | US2013178391 |
| OPPOSITION | US2015071910 |
| OPPOSITION | WO2012135408 |
| OPPOSITION | WO2014165422 |
| OPPOSITION | WO2014194293 |
| OPPOSITION | WO2015094992 |
| OPPOSITION | WO2015094995 |
| OPPOSITION | WO2015094996 |
| OPPOSITION | WO2015119930 |
| SEARCH | US2015071910 |
| SEARCH | WO2012038068 |
| SEARCH | WO2014009535 |
| SEARCH | WO2015035112 |
NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.
| Citation Phase | Reference Text |
|---|---|
| OPPOSITION | - Anonymous, "Highlights of prescribing information", Keytruda Prescribing Information, (20140900), pages 1 - 16, XP055847902 |
| OPPOSITION | - Anonymous, "Yervoy 5 mg/ml concentrate solution for infusion' - summary of product characteristics", Electronic Medicines Compendium, (20210912), pages 1 - 28, XP055848070 |
| OPPOSITION | - BROOKS, J.D., "Translational genomics : The challenge of developing cancer biomarkers", Genome Res, (20120200), vol. 22, no. 2, pages 183 - 187, XP055848069 |
| OPPOSITION | - Goosens N., Nakagawa S., Shun X., Hoshida Y., "Cancer biomarker discovery and validation", Transl Cancer Res., (20150600), vol. 4, no. 3, pages 256 - 269, XP055847908 |
| OPPOSITION | - Lal N., Beggs A. D., Willcox B. E., Middleton G. W., "An immunogenomic stratification of colorectal cancer : Implications for development of targeted immunotherapy", Oncolmmunology, (20150300), vol. 4, no. 3, page e976052 |
| OPPOSITION | - Lal N., Beggs A. D., Willcox B. E., Middleton G. W., "An immunogenomic stratification of colorectal cancer : Implications for development of targeted immunotherapy", Oncolmmunology, (20150300), vol. 4, no. 3, page e976052, XP055248283 |
| SEARCH | - L Chow ET AL, "Biomarkers and response to pembrolizumab (pembro) in recurrent/metastatic head and neck squamous cell carcinoma (R/M HNSCC)", (20160501), URL: http://ascopubs.org/doi/abs/10.1200/JCO.2016.34.15_suppl.6010, (20180817), XP055500554 |
Get a free citation report including examiner, opposition, and international search citations.
Get Citation ReportThe dossier documents provide a comprehensive record of the patent’s prosecution history - including filings, correspondence, and decisions made by patent offices - and are crucial for understanding the patent’s legal journey and any challenges it may have faced during examination.
Date
Description
Get instant alerts for new documents
Sep 19, 2024
Sep 19, 2024
Sep 11, 2024
Sep 11, 2024
Sep 11, 2024
Sep 11, 2024
Sep 11, 2024
Jun 18, 2024
Jun 18, 2024
Jun 18, 2024
Jun 17, 2024
Refund of fees
Search/Exam
Jun 13, 2024
Jun 13, 2024
Jun 13, 2024
Jun 7, 2024
(Electronic) Receipt
Appeal
Jun 7, 2024
Jun 7, 2024
Withdrawal of an appeal
Appeal
Apr 12, 2024
Apr 12, 2024
Apr 8, 2024
(Electronic) Receipt
Appeal
Apr 8, 2024
Apr 8, 2024
Notice of appeal
Appeal
Feb 9, 2024
Feb 9, 2024
Feb 9, 2024
Feb 9, 2024
Feb 9, 2024
Feb 9, 2024
Feb 9, 2024
Feb 9, 2024
Feb 9, 2024
Means of redress
OPPO
Feb 9, 2024
Feb 9, 2024
Feb 9, 2024
Feb 9, 2024
Feb 9, 2024
Feb 9, 2024
Feb 9, 2024
Feb 9, 2024
Jan 22, 2024
Jan 17, 2024
Jan 16, 2024
Jan 16, 2024
Jan 16, 2024
Description
OPPO
Jan 16, 2024
Jan 16, 2024
Nov 22, 2023
Nov 21, 2023
Nov 16, 2023
Nov 16, 2023
Nov 16, 2023
Nov 15, 2023
Nov 15, 2023
Nov 15, 2023
Nov 15, 2023
Nov 15, 2023
Nov 15, 2023
Nov 15, 2023
Nov 15, 2023
Nov 15, 2023
Nov 15, 2023
Nov 15, 2023
Nov 15, 2023
Nov 15, 2023
Nov 15, 2023
Nov 15, 2023
Nov 15, 2023
Nov 15, 2023
Nov 15, 2023
Feb 8, 2023
Feb 8, 2023
Feb 8, 2023
Feb 7, 2023
Feb 7, 2023
Feb 7, 2023
Feb 7, 2023
Feb 7, 2023
Feb 7, 2023
Feb 7, 2023
Sep 19, 2022
Sep 12, 2022
Sep 12, 2022
Sep 12, 2022
Sep 12, 2022
Sep 12, 2022
Sep 5, 2022
Annexes in respect of a client data request
Search/Exam
Sep 5, 2022
Annexes in respect of a client data request
Search/Exam
Sep 5, 2022
Letter accompanying subsequently filed items
Search/Exam
Sep 5, 2022
Sep 5, 2022
Aug 26, 2022
Aug 18, 2022
Annexes in respect of a client data request
Search/Exam
Aug 18, 2022
General authorisation
Search/Exam
Aug 18, 2022
Letter concerning fees and payments
Search/Exam
Aug 18, 2022
Aug 18, 2022
Mar 10, 2022
Feb 21, 2022
Feb 15, 2022
Feb 15, 2022
Feb 15, 2022
Feb 15, 2022
Feb 15, 2022
Feb 15, 2022
Feb 15, 2022
Feb 15, 2022
Feb 15, 2022
Feb 15, 2022
Feb 15, 2022
Feb 15, 2022
Feb 15, 2022
Feb 15, 2022
Feb 15, 2022
Feb 15, 2022
Feb 15, 2022
Feb 15, 2022
Oct 5, 2021
Oct 5, 2021
Sep 28, 2021
Sep 15, 2021
Sep 15, 2021
Sep 15, 2021
Sep 15, 2021
Sep 15, 2021
Sep 15, 2021
Sep 15, 2021
Sep 15, 2021
Sep 15, 2021
Sep 15, 2021
Sep 15, 2021
Sep 15, 2021
Sep 15, 2021
Sep 15, 2021
Sep 15, 2021
Sep 15, 2021
Sep 15, 2021
Sep 15, 2021
Sep 15, 2021
Sep 15, 2021
Sep 15, 2021
Sep 15, 2021
Sep 15, 2021
Sep 15, 2021
Sep 15, 2021
Sep 15, 2021
Jan 11, 2021
Dec 15, 2020
Document concerning representation
Search/Exam
Nov 19, 2020
Decision to grant a European patent
Search/Exam
Nov 6, 2020
(Electronic) Receipt
Search/Exam
Nov 6, 2020
Filing of the translations of the claims
Search/Exam
Nov 6, 2020
French translation of claims
Search/Exam
Nov 6, 2020
German translation of the claims
Search/Exam
Nov 6, 2020
Letter accompanying subsequently filed items
Search/Exam
Jul 1, 2020
Jul 1, 2020
Jul 1, 2020
Intention to grant (signatures)
Search/Exam
Jul 1, 2020
Text intended for grant (clean copy)
Search/Exam
Jul 1, 2020
Jun 4, 2020
(Electronic) Receipt
Search/Exam
Jun 4, 2020
Amended description with annotations
Search/Exam
Jun 4, 2020
Description
Search/Exam
Jun 4, 2020
Letter accompanying subsequently filed items
Search/Exam
Jun 4, 2020
Apr 15, 2020
Apr 8, 2020
(Electronic) Receipt
Search/Exam
Apr 8, 2020
Dec 4, 2019
Annex to the communication
Search/Exam
Dec 4, 2019
Communication from the Examining Division
Search/Exam
Nov 26, 2019
Examination started
Search/Exam
Jun 27, 2019
(Electronic) Receipt
Search/Exam
Jun 27, 2019
Jun 27, 2019
Amended claims with annotations
Search/Exam
Jun 27, 2019
Amendments received before examination
Search/Exam
Jun 27, 2019
Letter accompanying subsequently filed items
Search/Exam
Jan 3, 2019
Dec 7, 2018
Dec 7, 2018
European search opinion
Search/Exam
Dec 7, 2018
Information on Search Strategy
Search/Exam
Dec 7, 2018
Supplementary European search report
Search/Exam
Nov 14, 2018
(Electronic) Receipt
Search/Exam
Nov 14, 2018
Letter accompanying subsequently filed items
Search/Exam
Nov 14, 2018
Matter concerning the application
Search/Exam
Sep 4, 2018
Sep 4, 2018
Information on Search Strategy
Search/Exam
Sep 4, 2018
Partial European search report
Search/Exam
Sep 4, 2018
Aug 17, 2018
Search started
Search/Exam
Jan 24, 2018
Nov 29, 2017
Nov 27, 2017
Communication to designated inventor
Search/Exam
Nov 27, 2017
Communication to designated inventor
Search/Exam
Nov 27, 2017
Communication to designated inventor
Search/Exam
Nov 27, 2017
Communication to designated inventor
Search/Exam
Nov 27, 2017
Communication to designated inventor
Search/Exam
Nov 27, 2017
Communication to designated inventor
Search/Exam
Nov 6, 2017
(Electronic) Receipt
Search/Exam
Nov 6, 2017
Nov 6, 2017
Amended claims with annotations
Search/Exam
Nov 6, 2017
Request for entry into the European phase
Search/Exam
Oct 31, 2017
Aug 25, 2017
Information on entry into European phase
Search/Exam
Nov 7, 2016
Oct 20, 2016
Copy of the international search report
Search/Exam
Oct 20, 2016
Published international application - A1
Search/Exam