The patent EP3294323 was granted to Belur on Oct 13, 2021. The application was originally filed on May 13, 2016 under application number EP16797013A. The patent is currently recorded with a legal status of "Opposition Rejected".

Patent oppositions filed by competitors challenge the validity of a granted patent. These oppositions are typically based on claims of prior art, lack of novelty, or non-obviousness. They are a key part of the process for determining a patent's strength and enforceability.
Patent citations refer to prior patents cited during different phases such as opposition or international search.
| Citation Phase | Publication Number |
|---|---|
| DESCRIPTION | US5656785 |
| DESCRIPTION | US5658776 |
| DESCRIPTION | US8609088 |
| DESCRIPTION | WO2008049588 |
| DESCRIPTION | WO2014186579 |
| DESCRIPTION | WO9413788 |
| DESCRIPTION | WO9513392 |
| DESCRIPTION | WO9617947 |
| DESCRIPTION | WO9823018 |
| DESCRIPTION | WO9827204 |
| INTERNATIONAL-SEARCH-REPORT | US2014088179 |
| INTERNATIONAL-SEARCH-REPORT | WO2014186579 |
| INTERNATIONAL-SEARCH-REPORT | WO2015013148 |
| OPPOSITION | WO2014186579 |
| OPPOSITION | WO2016187017 |
| SEARCH | US2012009268 |
| SEARCH | US2012288489 |
| SEARCH | US2013039888 |
NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.
| Citation Phase | Reference Text |
|---|---|
| OPPOSITION | - LAOHARAWEE et al., "AAV9 Mediated Correction of Iduronate- 2-Sulfatase Deficiency in the Central Nervous System of Mucopolysaccharidosis Type II Mice", Molecular Therapy, (20150501), vol. 23, page S146, XP055946938 |
| OPPOSITION | - Lebkowski Jane S, "American Society of Gene & Cell Therapy 18th Annual Meeting", Molecular Therapy, (20150501), vol. 23, no. S1, pages 1 - 14, XP093103823 |
| OPPOSITION | - NEUFELD et al., "The Mucopolysaccharidoses", Online Metabolic & Molecular Bases of Inherited Disease, (20010101), pages 3421 - 3452, XP009167340 |
| OPPOSITION | - Niemir Natalia, "Gene transfer in the Sandhoff murine model using a specific recombinant AAV9 vector", These UNIVERSITE PARIS DESCARTES, (20131125), pages 1 - 209, XP055946956 |
| OPPOSITION | - Polito Vinicia Assunta, "IDS crossing of the Blood-Brain Barrier corrects CNS defects in MPSII mice", Thesis EUROPEAN SCHOOL OF MOLECULAR MEDICINE NAPLES SITE, (20100101), pages 1 - 82, URL: http://www.fedoa.unina.it/4310/1/Polito.pdf, XP055946947 |
| OPPOSITION | - Polito Vinicia Assunta, Maria Pia Cosma, "IDS Crossing of the Blood-Brain Barrier Corrects CNS Defects in MPSII Mice", American Journal Human Genetic (Supplemental Data), (20090801), pages 1 - 9, XP093102632 |
| OPPOSITION | - RODER et al., NEUROCOGNITION AND SOCIAL COGNITION IN SCHIZOPHRENIA PATIENTS, (20100101), vol. 177 |
| OPPOSITION | - Rodriguiz Ramona Marie, William C Wetsel, "Chapter 12 Assessments of Cognitive Deficits in Mutant Mice", Rodriguiz Ramona Marie, William C Wetsel, Levin E D, Buccafusco J J, Animal Models of Cognitive Impairment, CRC Press/Taylor & Francis, (20060101), pages 1 - 53, XP093102630 |
| OPPOSITION | - Vinicia Assunta Polito, and Maria Pia Cosma, "IDS Crossing of the Blood-Brain Barrier Corrects CNS Defects in MPSII Mice", The American Journal of Human Genetics, US , (20090814), vol. 85, no. 2, doi:10.1016/j.ajhg.2009.07.011, ISSN 0002-9297, pages 296 - 301, XP002692097 |
| OPPOSITION | - Kanut Laoharawee, Kelly M. Podetz-Pedersen, Tam T. Nguyen, Laura B. Evenstar, Kelley F. Kitto, Zhenhong Nan, Carolyn A. Fairbanks, Walter C. Low, Karen F. Kozarsky, R. Scott Mcivor, "Prevention of Neurocognitive Deficiency in Mucopolysaccharidosis Type II Mice by Central Nervous System–Directed, AAV9-Mediated Iduronate Sulfatase Gene Transfer", Human Gene Therapy, GB , (20170801), vol. 28, no. 8, doi:10.1089/hum.2016.184, ISSN 1043-0342, pages 626 - 638, XP055401129 |
| OPPOSITION | - LAOHARAWEE et al., "Prevention of Neurocognitive Deficiency in Mucopolysaccharidosis Type II Mice by Central Nervous System-Directed, AAV9-Mediated Iduronate Sulfatase Gene Transfer", Human Gene Therapy, (20170505), vol. 28, no. 8, doi:10.1089/hum.2016.184, pages 626 - 638, XP055401129 |
| OPPOSITION | - WOLF et al., "Gene Therapy for Neurologic Manifestations of Mucopolysaccharidoses", Expert Opin Drug Deliv, (20141216), vol. 12, no. 2, doi:10.1517/17425247.2015.966682, pages 283 - 296, XP055401272 |
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German translation of the claims
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European search opinion
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Matter concerning the application
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